Ion transporters and ischemic mitochondrial dysfunction

Cell Adhesion and Migration

Volumn 3, Issue 1, 2009, Pages 94-98

  Liu, Yan ^a,b   Liu, Xiang Jun ^b   Sun, Dandan ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b Tsinghua University   (China)

Author keywords

Apoptosis; Changes of mitochondrial Ca2+; Cytochrome c; Intracellular Ca2+ dysregulation; Ischemia

Indexed keywords

CALCIUM; CARRIER PROTEIN; CYTOCHROME C; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; SODIUM CALCIUM EXCHANGE PROTEIN;

APOPTOSIS; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CELL DAMAGE; CHLORIDE TRANSPORT; DEPOLARIZATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; HUMAN; ION TRANSPORT; ISCHEMIA; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL PERMEABILITY; NONHUMAN; OUTER MEMBRANE; OXIDATIVE PHOSPHORYLATION; REVIEW; STROKE; TRAUMATIC BRAIN INJURY;

EID: 67049136005     PISSN: 19336918     EISSN: 19336926     Source Type: Journal    
DOI: 10.4161/cam.3.1.7516     Document Type: Review

References (59)

1. McBride HM, Neuspiel M, Wasiak S. Mitochondria: more than just a powerhouse. Curr Biol 2006; 16:551-560
2. Orrenius S, Zhivotovsky B, Nicotera P. Regulation of cell death: the calcium-apoptosis link. Nat Rev Mol Cell Biol 2003; 4:552-565 (Pubitemid 36773407)
3. Bernardi P and Rasola A. Calcium and cell death: the mitochondrial connection. Subcell Biochem 2007; 45:481-506.
4. 2+ changes in rat forebrain neurones. J Physiol (Lond) 1998; 509:103-116
5. Brookes PS, Yoon Y, Robotham JL, Anders MW, Sheu SS. Calcium, ATP and ROS: a mitochondrial love-hate triangle. Am J Physiol Cell Physiol 2004; 287:817-833 (Pubitemid 39238305)
6. Cao G, Xiao M, Sun F, Xiao X, Pei W, Li J, et al. Cloning of a novel Apaf-1-interacting protein: a potent suppressor of apoptosis and ischemic neuronal cell death. J Neurosci 2004; 24:6189-6201 (Pubitemid 38891110)
7. 2+ signaling in astrocytes in an in vitro ischemic model. J Neurosci 2004; 24:9585-9597
8. 2+ exchange in mitochondrial dysfunction in astrocytes following in vitro ischemia. Am J Physiol Cell Physiol 2007; 292:1113-1122
9. Luo J, Wang Y, Chen H, Kintner DB, Cramer SW, Gerdts JK, et al. A concerted role of Na(+)-K(+)-Cl(-) cotransporter and Na(+)/Ca(2+) exchanger in ischemic damage. J Cereb Blood Flow Metab 2008; 28:737-746
10. Chen H, Kintner DB, Jones M, Matsuda T, Baba A, Kiedrowski L, et al. AMPA-mediated excitotoxicity in oligodendrocytes: role for Na(+)-K(+)-Cl(-) co-transport and reversal of Na(+)/Ca(2+) exchanger. J Neurochem 2007; PM:17490438.
11. Chen H, Luo J, Kintner DB, Shull GE, Sun D. Na+-dependent chloride transporter (NKCC1)-null mice exhibit less gray and white matter damage after focal cerebral ischemia. J Cereb Blood Flow Metab 2005; 25:54-66. (Pubitemid 40096897)
12. Clapham DE. Calcium signaling. Cell 1995; 80:259-268
13. Fall CP and Keizer JE. Mitochondrial modulation of intracellular Ca(2+) signaling. J Theor Biol 2001; 210:151-165
14. Lipton P. Ischemic cell death in brain neurons. Physiol Rev 1999; 79:1431-1568 (Pubitemid 29473320)
15. Saris NE and Eriksson KO. Mitochondrial dysfunction in ischaemia-reperfusion. Acta Anaesthesiol Scand Suppl 1995; 107:171-176
16. Grinwald PM. Calcium uptake during post-ischemic reperfusion in the isolated rat heart: influence of extracellular sodium. J Mol Cell Cardiol 1982; 14:359-365 (Pubitemid 12056783)
17. Gunter TE, Yule DI, Gunter KK, Eliseev RA, Salter JD. Calcium and mitochondria. FEBS Lett 2004; 567:96-102.
18. Crompton M. The mitochondrial permeability transition pore and its role in cell death. Biochem J 1999; 341:233-249 (Pubitemid 29373645)
19. Brustovetsky N, Brustovetsky T, Jemmerson R, Dubinsky JM. Calcium-induced cytochrome c release from CNS mitochondria is associated with the permeability transition and rupture of the outer membrane. J Neurochem 2002; 80:207-218 (Pubitemid 34809366)
20. Hunter DR and Haworth RA. The Ca2+-induced membrane transition in mitochondria I. The protective mechanisms. Arch Biochem Biophys 1979; 195:453-459
21. Haworth RA and Hunter DR. The Ca2+-induced membrane transition in mitochondria II. Nature of the Ca2+ trigger site. Arch Biochem Biophys 1979; 195:460-467
22. Rasola A and Bernardi P. The mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis. Apoptosis 2007; 12: 815-833. (Pubitemid 46653292)
23. Strasser A, O'Connor L, Dixit VM. Apoptosis signaling. Annu Rev Biochem 2000; 69:217-245
24. Eskes R, Desagher S, Antonsson B, Martinou JC. Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane. Mol Cell Biol 2000; 20:929-935 (Pubitemid 30044230)
25. Antonsson B, Conti F, Ciavatta A, Montessuit S, Lewis S, Martinou I, et al. Inhibition of Bax channel-forming activity by Bcl-2. Science 1997; 277:370-372 (Pubitemid 27450709)
26. Lindsten T, Ross AJ, King A, Zong WX, Rathmell JC, Shiels HA, et al. The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. Mol Cell 2000; 6:1389-1399 (Pubitemid 32045931)
27. Ott M, Robertson JD, Gogvadze V, Zhivotovsky B, Orrenius S. Cytochrome c release from mitochondria proceeds by a two-step process. Proc Natl Acad Sci USA 2002; 99:1259-1263 (Pubitemid 34136480)
28. Petrosillo G, Ruggiero FM, Pistolese M, Paradies G. Reactive oxygen species generated from the mitochondrial electron transport chain induce cytochrome c dissociation from beefheart submitochondrial particles via cardiolipin peroxidation. Possible role in the apoptosis. FEBS Lett 2001; 509:435-438 (Pubitemid 34031974)
29. 2+- stimulated generation of reactive oxygen species by the respiratory chain. Biochemistry 1999; 38:13279-13287
30. Boehning D, Patterson RL, Sedaghat L, Glebova NO, Kurosaki T, Snyder SH. Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis. Nat Cell Biol 2003; 5:1051-1061
31. Boehning D, Patterson RL, Snyder SH. Apoptosis and calcium: new roles for cytochrome c and inositol 1,4,5-trisphosphate. Cell Cycle 2004; 3:252-254 (Pubitemid 41359065)
32. Beresewicz M, Kowalczyk JE, Zablocka B. Cytochrome c binds to inositol (1,4,5) trisphosphate and ryanodine receptors in vivo after transient brain ischemia in gerbils. Neurochem Int 2006; 48:568-571
33. Haas M and Forbush B, III. The Na-K-Cl cotransporter of secretory epithelia. Annu Rev Physiol 2000; 62:515-534
34. Russell JM. Sodium-potassium-chloride cotransport. Physiol Rev 2000; 80:211-276 (Pubitemid 30060565)
35. 3H]bumetanide binding to membranes isolated from dog kidney outer medulla. Relationship to the Na, K, Cl co-transport system. J Biol Chem 1983; 258:11787-11792
36. Xu JC, Lytle C, Zhu TT, Payne JA, Benz E Jr, Forbush B, III. Molecular cloning and functional expression of the bumetanide-sensitive Na-K-Cl cotransporter. Proc Natl Acad Sci USA 1994; 91:2201-2205
37. Schomberg SL, Su G, Haworth RA, Sun D. Stimulation of Na-K-2Cl cotransporter in neurons by activation of Non-NMDA ionotropic receptor and group-I mGluRs. J Neurophysiol 2001; 85:2563-2575 (Pubitemid 32525533)
38. Beck J, Lenart B, Kintner DB, Sun D. Na-K-Cl cotransporter contributes to glutamatemediated excitotoxicity. J Neurosci 2003; 23:5061-5068 (Pubitemid 36793233)
39. Su G, Kintner DB, Sun D. Contribution of Na(+)-K(+)-Cl(-) cotransporter to high-[K(+)] (o)-induced swelling and EAA release in astrocytes. Am J Physiol Cell Physiol 2002; 282:1136-1146
40. Annunziato L, Pignataro G, Di Renzo GF. Pharmacology of brain Na(+)/Ca(2+) exchanger: from molecular biology to therapeutic perspectives. Pharmacol Rev 2004; 56:633-654
41. Lee SL, Yu AS, Lytton J. Tissue-specific expression of Na(+)-Ca(2+) exchanger isoforms. J Biol Chem 1994; 269:14849-14852
42. Nicoll DA, Ottolia M, Philipson KD. Toward a topological model of the NCX1 exchanger. Ann N Y Acad Sci 2002; 976:11-18 (Pubitemid 36126864)
43. Minelli A, Castaldo P, Gobbi P, Salucci S, Magi S, Amoroso S. Cellular and subcellular localization of Na(+)-Ca(2+) exchanger protein isoforms, NCX1, NCX2 and NCX3 in cerebral cortex and hippocampus of adult rat. Cell Calcium 2007; 41:221-234
44. Kang TM and Hilgemann DW. Multiple transport modes of the cardiac Na+/Ca2+ exchanger. Nature 2004; 427:544-548
45. Iwamoto T. Na(+)/Ca(2+) exchange as a drug target - insights from molecular pharmacology and genetic engineering. Ann N Y Acad Sci 2007; 1099:516-528
46. Walz W. Role of glial cells in the regulation of the brain ion microenvironment. Prog Neurobiol 1989; 33:309-333 (Pubitemid 19263462)
47. +. Neuroscience 1999; 93:285-292
48. + exchanger isoform 1-null mice after in vitro and in vivo ischemia. J Neurosci 2005; 25:11256-11268
49. + homeostasis in rat spinal cord astrocytes. J Neurosci 1998; 18:3554-3562
50. Silver IA, Deas J, Erecinska M. Ion homeostasis in brain cells: differences in intracellular ion responses to energy limitation between cultured neurons and glial cells. Neuroscience 1997; 78:589-601. (Pubitemid 27170347)
51. Flemmer AW, Gimenez I, Dowd BF, Darman RB, Forbush B. Activation of the Na-K-Cl cotransporter NKCC1 detected with a phospho-specific antibody. J Biol Chem 2002; 277:37551-37558
52. Stys PK. Anoxic and ischemic injury of myelinated axons in CNS white matter: from mechanistic concepts to therapeutics. J Cereb Blood Flow Metab 1998; 18:2-25. (Pubitemid 28019008)
53. + exchange in spinal cord white matter injury at physiological temperature. J Neurophysiol 2000; 84:1116-1119
54. Goldman WF, Yarowsky PJ, Juhaszova M, Krueger BK, Blaustein MP. Sodium/calcium exchange in rat cortical astrocytes. J Neurosci 1994; 14:5834-5843 (Pubitemid 24307780)
55. 2+ exchanger in cultured rat astrocytes. Brain Res 2000; 887:98-109.
56. + exchange activity in response to in vitro ischemia in part depends on activation of extracellular signalregulatory kinase. Am J Physiol Cell Physiol 2005; 289:934-945
57. 2+ exchange in cortical astrocytes. Glia 2005; 51:35-46.
58. 2+ exchange in hypoxiarelated acute astrocyte death. Glia 2005; 49:143-152
59. Luo J, Wang Y, Chen H, Kintner DB, Cramer SW, Gerdts JK, et al. A concerted role of Na(+)-K(+)-Cl(-) cotransporter and Na(+)/Ca(2+) exchanger in ischemic damage. J Cereb Blood Flow Metab 2008; 28, 737-746.