The integrin α 2β 1 agonist, aggretin, promotes proliferation and migration of VSMC through NF-kB translocation and PDGF production

British Journal of Pharmacology

Volumn 156, Issue 5, 2009, Pages 846-856

  Chung, Ching Hu ^a   Lin, Kuan Ting ^a   Chang, Chien Hsin ^a   Peng, Hui Chin ^a   Huang, Tur Fu ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Aggretin; Integrin 2 1; NF kB; PDGF; Smooth muscle cell

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; AGGRETIN; ANGIOGENIC FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY ALL2E10; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN TYROSINE KINASE; PYRROLIDINE DITHIOCARBAMATE; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 2; LECTIN; PHOSPHOLIPASE C; PLATELET-DERIVED GROWTH FACTOR BB; RHODOCYTIN PROTEIN, CALLOSELASMA RHODOSTOMA; VIPER VENOM;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL MOTION; CYTOLOGY; DRUG EFFECT; DRUG POTENTIATION; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN TRANSPORT;

ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INTEGRIN ALPHA2BETA1; LECTINS, C-TYPE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTEIN TRANSPORT; RATS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TYPE C PHOSPHOLIPASES; VIPER VENOMS;

EID: 66949161978     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2008.00095.x     Document Type: Article

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