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Volumn 8, Issue 5, 2009, Pages 1319-1327

Genetic inhibition of telomerase results in sensitization and recovery of breast tumor cells

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; DOXORUBICIN; PACLITAXEL; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

EID: 66849138225     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-08-0849     Document Type: Article
Times cited : (14)

References (30)
  • 1
    • 0032412818 scopus 로고    scopus 로고
    • The relationship between prognostic and predictive factors in the management of breast cancer
    • DOI 10.1023/A:1006141703224
    • Henderson IC, Patek AJ. The relationship between prognostic and predictive factors in the management of breast cancer. Breast Cancer Res Treat 1998;52:261-288 (Pubitemid 29056100)
    • (1998) Breast Cancer Research and Treatment , vol.52 , Issue.1-3 , pp. 261-288
    • Henderson, I.C.1    Patek, A.J.2
  • 2
    • 27144438252 scopus 로고    scopus 로고
    • Roles of tumor suppressor and telomere maintenance genes in cancer and aging - An epidemiological study
    • DOI 10.1093/carcin/bgi126
    • Gu J, Spitz MR, Zhao H, et al. Roles of tumor suppressor and telomere maintenance genes in cancer and aging - an epidemiological study. Carcinogenesis 2005;26:1741-1747 (Pubitemid 41487989)
    • (2005) Carcinogenesis , vol.26 , Issue.10 , pp. 1741-1747
    • Gu, J.1    Spitz, M.R.2    Zhao, H.3    Lin, J.4    Grossman, H.B.5    Dinney, C.P.6    Wu, X.7
  • 3
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • DOI 10.1038/345458a0
    • Harley CB, Futcher AB, Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature 1990;345:458-460 (Pubitemid 20178256)
    • (1990) Nature , vol.345 , Issue.6274 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 5
    • 0031047642 scopus 로고    scopus 로고
    • Block in anaphase chromosome separation caused by a telomerase template mutation
    • DOI 10.1126/science.275.5305.1478
    • Kirk KE, Harmon BP, Reichardt IK, Sedat JW, Blackburn EH. Block in anaphase chromosome separation caused by a telomerase template mutation. Science 1997;275:1478-1481 (Pubitemid 27111296)
    • (1997) Science , vol.275 , Issue.5305 , pp. 1478-1481
    • Kirk, K.E.1    Harmon, B.P.2    Reichardt, I.K.3    Sedat, J.W.4    Blackburn, E.H.5
  • 6
    • 0037148277 scopus 로고    scopus 로고
    • Protection of mammalian telomeres
    • DOI 10.1038/sj/onc/1205080
    • de Lange T. Protection of mammalian telomeres. Oncogene 2002;21:532-540 (Pubitemid 34146253)
    • (2002) Oncogene , vol.21 , Issue.4 REV. ISS. 1 , pp. 532-540
    • De Lange, T.1
  • 8
    • 36349005782 scopus 로고    scopus 로고
    • Anticancer therapy targeting telomeres and telomerase: Current status
    • Parkinson EK, Minty F. Anticancer therapy targeting telomeres and telomerase: current status. BioDrugs 2007;21:375-385 (Pubitemid 350145446)
    • (2007) BioDrugs , vol.21 , Issue.6 , pp. 375-385
    • Parkinson, E.K.1    Minty, F.2
  • 10
    • 0033568462 scopus 로고    scopus 로고
    • Telomere shortening and apoptosis in telomerase-inhibited human tumor cells
    • DOI 10.1101/gad.13.18.2388
    • Zhang X, Mar V, Zhou W, Harrington L, Robinson MO. Telomere shortening and apoptosis in telomerase-inhibited human tumor cells. Genes Dev 1999;13:2388-2399 (Pubitemid 29453610)
    • (1999) Genes and Development , vol.13 , Issue.18 , pp. 2388-2399
    • Zhang, X.1    Mar, V.2    Zhou, W.3    Harrington, L.4    Robinson, M.O.5
  • 11
    • 0034352944 scopus 로고    scopus 로고
    • The hTERTα splice variant is a dominant negative inhibitor of telomerase activity
    • Colgin LM, Wilkinson C, Englezou A, Kilian A, Robinson MO, Reddel RR. The hTERTα splice variant is a dominant negative inhibitor of telomerase activity. Neoplasia 2000;2:426-432 (Pubitemid 32044788)
    • (2000) Neoplasia , vol.2 , Issue.5 , pp. 426-432
    • Colgin, L.M.1    Wilkinson, C.2    Englezou, A.3    Kilian, A.4    Robinson, M.O.5    Reddel, R.R.6
  • 13
    • 32044431688 scopus 로고    scopus 로고
    • Induction of nitric oxide synthase-dependent telomere shortening after functional inhibition of Hsp90 in human tumor cells
    • DOI 10.1128/MCB.26.4.1452-1462.2006
    • Compton SA, Elmore LW, Haydu K, Jackson-Cook CK, Holt SE. Induction ofnitric oxide synthase-dependent telomere shortening after functional inhibition of Hsp90 in human tumor cells. Mol Cell Biol 2006;26:1452-1462 (Pubitemid 43202570)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.4 , pp. 1452-1462
    • Compton, S.A.1    Elmore, L.W.2    Haydu, K.3    Jackson-Cook, C.K.4    Holt, S.E.5
  • 14
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini L, Blömer U, Gallay P, et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996;272:263-267
    • (1996) Science , vol.272 , pp. 263-267
    • Naldini, L.1    Blömer, U.2    Gallay, P.3
  • 15
    • 0029047362 scopus 로고
    • A biomarker that identifies senescent human cells in culture and in aging skin in vivo
    • Dimri GP, Lee X, Basile G, et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A 1995;92:9363-9367
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 9363-9367
    • Dimri, G.P.1    Lee, X.2    Basile, G.3
  • 17
    • 0036834259 scopus 로고    scopus 로고
    • Inhibition of human telomerase enhances the effect of chemotherapeutic agents in lung cancer cells
    • Misawa M, Tauchi T, Sashida G, et al. Inhibition of human telomerase enhances the effect of chemotherapeutic agents in lung cancer cells. Int J Oncol 2002;21:1087-1092
    • (2002) Int J Oncol , vol.21 , pp. 1087-1092
    • Misawa, M.1    Tauchi, T.2    Sashida, G.3
  • 18
    • 22144492967 scopus 로고    scopus 로고
    • Efficient inhibition of human telomerase reverse transcriptase expression by RNA interference sensitizes cancer cells to ionizing radiation and chemotherapy
    • DOI 10.1089/hum.2005.16.859
    • Nakamura M, Masutomi K, Kyo S, et al. Efficient inhibition of human telomerase reverse transcriptase expression by RNA interference sensitizes cancer cells to ionizing radiation and chemotherapy. Hum Gene Ther 2005;16:859-868 (Pubitemid 40982334)
    • (2005) Human Gene Therapy , vol.16 , Issue.7 , pp. 859-868
    • Nakamura, M.1    Masutomi, K.2    Kyo, S.3    Hashimoto, M.4    Maida, Y.5    Kanaya, T.6    Tanaka, M.7    Hahn, W.C.8    Inoue, M.9
  • 19
    • 23944516595 scopus 로고    scopus 로고
    • Pharmacological telomerase inhibition can sensitize drug-resistant and drug-sensitive cells to chemotherapeutic treatment
    • DOI 10.1124/mol.105.011494
    • Ward RJ, Autexier C. Pharmacological telomerase inhibition can sensitize drug-resistant and drug-sensitive cells to chemotherapeutic treatment. Mol Pharm 2005;68:779-786 (Pubitemid 41206032)
    • (2005) Molecular Pharmacology , vol.68 , Issue.3 , pp. 779-786
    • Ward, R.J.1    Autexier, C.2
  • 20
    • 33748316825 scopus 로고    scopus 로고
    • Telomerase inhibition enhances the response to anticancer drug treatment in human breast cancer cells
    • DOI 10.1158/1535-7163.MCT-06-0033
    • Cerone MA, Londoño-Vallejo JA, Autexier C. Telomerase inhibition enhances the response to anticancer drug treatment in human breast cancer cells. Mol Cancer Ther 2006;5:1669-1675 (Pubitemid 44323234)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.7 , pp. 1669-1675
    • Cerone, M.A.1    Londono-Vallejo, J.A.2    Autexier, C.3
  • 22
    • 3342972121 scopus 로고    scopus 로고
    • Does a sentinel or a subset ofsh ort telomeres determine replicative senescence?
    • Zou Y, Sfeir A, Gryaznov SM, Shay JW, Wright WE. Does a sentinel or a subset ofsh ort telomeres determine replicative senescence? Mol Biol Cell 2004;15:3709-3718
    • (2004) Mol Biol Cell , vol.15 , pp. 3709-3718
    • Zou, Y.1    Sfeir, A.2    Gryaznov, S.M.3    Shay, J.W.4    Wright, W.E.5
  • 24
    • 0142244336 scopus 로고    scopus 로고
    • DNA damage transiently increases TRF2 mRNA expression and telomerase activity
    • DOI 10.1038/sj.leu.2403086
    • Klapper W, Qian W, Schulte C, Parwaresch R. DNA damage transiently increases TRF2 mRNA expression and telomerase activity. Leukemia 2003;17:2007-2015 (Pubitemid 37322131)
    • (2003) Leukemia , vol.17 , Issue.10 , pp. 2007-2015
    • Klapper, W.1    Qian, W.2    Schulte, C.3    Parwaresch, R.4
  • 25
    • 0035878750 scopus 로고    scopus 로고
    • Telomerase inhibition in RenCa, a murine tumor cell line with short telomeres, by overexpression of a dominant negative mTERT mutant, reveals fundamental differences in telomerase regulation between human and murine cells
    • Sachsinger J, González-Suárez E, Samper E, Heicappell R, Müller M, Blasco MA. Telomerase inhibition in RenCa, a murine tumor cell line with short telomeres, by overexpression of a dominant negative mTERT mutant, reveals fundamental differences in telomerase regulation between human and murine cells. Cancer Res 2001;61:5580-5586 (Pubitemid 32694946)
    • (2001) Cancer Research , vol.61 , Issue.14 , pp. 5580-5586
    • Sachsinger, J.1    Gonzalez-Suarez, E.2    Samper, E.3    Heicappell, R.4    Muller, M.5    Blasco, M.A.6
  • 27
    • 2342570379 scopus 로고    scopus 로고
    • Hallmarks of senescence in carcinogenesis and cancer therapy
    • DOI 10.1038/sj.onc.1207518
    • Shay JW, Roninson IB. Hallmarks of senescence in carcinogenesis and cancer therapy. Oncogene 2004;23:2919-2933 (Pubitemid 38638853)
    • (2004) Oncogene , vol.23 , Issue.16 REV. ISS. 2 , pp. 2919-2933
    • Shay, J.W.1    Roninson, I.B.2
  • 28
    • 38349049184 scopus 로고    scopus 로고
    • Telomerase inhibition in a mouse cell line with long telomeres leads to rapid telomerase reactivation
    • Marie-Egyptienne DT, Brault ME, Zhu S, Autexier C. Telomerase inhibition in a mouse cell line with long telomeres leads to rapid telomerase reactivation. Exp Cell Res 2008;314:668-675
    • (2008) Exp Cell Res , vol.314 , pp. 668-675
    • Marie-Egyptienne, D.T.1    Brault, M.E.2    Zhu, S.3    Autexier, C.4
  • 29
    • 33749630045 scopus 로고    scopus 로고
    • Telomerase with mutated catalytic motifs has dominant negative effects on telomerase activity and inhibits cell growth
    • DOI 10.1016/j.bbrc.2006.09.125, PII S0006291X06021826
    • Rahman R, Mo L, Cui W. Telomerase with mutated catalytic motifs has dominant negative effects on telomerase activity and inhibits cell growth. Biochem Biophys Res Commun 2006;350:796-802. (Pubitemid 44547916)
    • (2006) Biochemical and Biophysical Research Communications , vol.350 , Issue.3 , pp. 796-802
    • Rahman, R.1    Mo, L.2    Cui, W.3
  • 30
    • 46749152214 scopus 로고    scopus 로고
    • Actions of human telomerase beyond telomeres
    • Cong Y, Shay JW. Actions of human telomerase beyond telomeres. Cell Res 2008;18:725-732
    • (2008) Cell Res , vol.18 , pp. 725-732
    • Cong, Y.1    Shay, J.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.