Bone-vascular axis in chronic kidney disease: A reality?

Clinical Journal of the American Society of Nephrology

Volumn 4, Issue 2, 2009, Pages 254-257

  London, Gérard M ^a,b  

^a Centre Hospitalier Manhes   (France)

^b PARIS CARDIOVASCULAR RESEARCH CENTER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR RUNX2;

ARTERIAL STIFFNESS; ATHEROGENESIS; BLOOD VESSEL CALCIFICATION; BONE DEMINERALIZATION; BONE TURNOVER; CHRONIC KIDNEY DISEASE; CORONARY ARTERY ATHEROSCLEROSIS; DYSLIPIDEMIA; EDITORIAL; HEMODIALYSIS; HUMAN; HYPERPHOSPHATEMIA; HYPERTENSION; INFLAMMATION; KIDNEY FAILURE; MINERAL METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; OSTEOPENIA; OSTEOPOROSIS; SECONDARY HYPERPARATHYROIDISM; VASCULAR SMOOTH MUSCLE; AGE; BONE REMODELING; CALCINOSIS; CHRONIC DISEASE; CORONARY ARTERY DISEASE; HOSPITALIZATION; ILIAC BONE; KIDNEY DISEASE; NOTE; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY; RENAL REPLACEMENT THERAPY; RISK ASSESSMENT; RISK FACTOR;

AGE FACTORS; BONE REMODELING; CALCINOSIS; CHRONIC DISEASE; CORONARY ARTERY DISEASE; HUMANS; ILIUM; KIDNEY DISEASES; ORGAN SIZE; RENAL DIALYSIS; RISK ASSESSMENT; RISK FACTORS; SEVERITY OF ILLNESS INDEX;

EID: 66849104250     PISSN: 15559041     EISSN: 1555905X     Source Type: Journal    
DOI: 10.2215/CJN.06661208     Document Type: Editorial

References (46)

1. Schoppet M, Shroff RC, Hofbauer LC, Shanahan CM: Exploring the biology of vascular calcification in chronic kidney disease: What's circulating? Kidney Int 73: 384-390, 2008 (Pubitemid 351186286)
2. Demer LL, Tintut Y: Vascular calcification: Pathobiology of multifaceted disease. Circulation 117: 2938-2948, 2008 (Pubitemid 351787058)
3. Moe S, Drüeke T, Cunningham J, Goodman W, Martin K, Olgaard K, Ott S, Sprague S, Lameire N, Eknoyan G: Definition, evaluation, and classification of renal osteodystrophy: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int 69: 1945-1953, 2006
4. Hamerman D: Osteoporosis and atherosclerosis: Biological linkage and the emergence of dual-purpose therapies. Q J Med 98: 467-484, 2005
5. Hak AE, Pols HA, van Hemert AM, Hofman A, Witteman JC: Progression of aortic calcification is associated with metacarpal bone loss during menopause: A population-based longitudinal study. Arterioscler Thromb Vasc Biol 20: 1926-1931, 2000
6. Schulz E, Arfai K, Liu X, Sayre J, Gilsanz V: Aortic calcification and the risk of osteoporosis and fractures. J Clin Endocrin Metab 89: 4246-4253, 2004 (Pubitemid 39244420)
7. Tanko LB, Christiansen C, Cox DA, Geiger MJ, McNabb MA, Cummings SR: Relationship between osteoporosis and cardiovascular disease in postmenopausal women. J Bone Mineral Res 20: 1912-1920, 2005
8. Carr JJ, Register TC, Hsu F-Ch, Lohman K, Lenchik L, Bowden DW, Langefeld CD, Xu J, Rich SS, Wagenknecht LE, Freedman BI: Calcified atherosclerotic plaque and bone mineral density in type 2 diabetes: The diabetes heart study. Bone 42: 43-52, 2008 (Pubitemid 350297171)
9. Sumino H, Ichikawa S, Kasama S, Takahashi T, Sakamoto H, Kumakura H, Takayama Y, Kanda T, Murakami M, Kurabayashi M: Elevated arterial stiffness in postmenopausal women with osteoporosis. Maturitas 55: 212-218, 2006 (Pubitemid 44404157)
10. Sumino H, Ichikawa S, Kasama S, Takahashi T, Sakamoto H, Kumakura H, Takayama Y, Kanda T, Murakami M, Kurabayashi M: Relationship between brachial arterial endothelial function and lumbar spine bone mineral density in postmenopausal women. Circ J 71: 1555-1559, 2007 (Pubitemid 47529656)
11. Braun J, Oldendorf M, Moshage W, Heidler R, Zeitler E, Luft FC: Electron-beam computed tomography in the evaluation of cardiac calcifications in chronic dialysis patients. Am J Kidney Dis 27: 394-401, 1996 (Pubitemid 26075849)
12. Barreto DV, Barreto FC, Carvalho AB, Cuppari L, Cendoroglo M, Draibe SA, Moyses RM, Neves KR, Jorgetti V, Blair A, Guiberteau R, Fernandes Canziani ME: Coronary calcification in hemodialysis patients: The contribution of traditional and uremia-related risk factors. Kidney Int 67: 1576-1582, 2005 (Pubitemid 40463138)
13. London GM, Marty C, Marchais SJ, Guérin AP, Métivier F, de Vernejoul MC: Arterial calcifications and bone histomorphometry in end-stage renal disease. J Am Soc Nephrol 15: 1943-1951, 2004
14. London GM, Marchais SJ, Guérin AP, Boutouyrie P, Métivier F, de Vernejoul MC: Association of bone activity, calcium load, aortic stiffness, and calcifications in ESRD. J Am Soc Nephrol 19: 1827-1835, 2008
15. Joki N, Hase H, Shiratake M, Kishi N, Tochigi S, Imamura Y: Calcaneal osteopenia is a new marker for arterial stiffness in chronic hemodialysis patients. Am J Nephrol 25: 196-202, 2005 (Pubitemid 41202740)
16. Raggi P, Bellasi A, Ferramosca E, Block GA, Muntner P: Pulse wave velocity is inversely related to vertebral bone density in hemodialysis patients. Hypertension 49: 1278-1284, 2007 (Pubitemid 46809369)
17. Toussaint ND, Lau KK, Strauss BJ, Polkinghorne KR, Kerr PG: Association between vascular calcification, arterial stiffness and bone mineral density in chronic kidney disease. Nephrol Dial Transplant 23: 586-593, 2008
18. Adragao T, Herberth J, Monier-Faugere M-C, Branscum AJ, Ferreira A, Frazao JM, Curto JD, Malluche HH: Low bone volume- a risk factor for coronary calcifications in hemodialysis patients. Clin J Am Soc Nephrol 4: 450-455, 2009
19. Majesky MW: Developmental basis of vascular smooth muscle diversity. Atheroscler Thromb Vasc Biol 27: 1248-1258, 2007 (Pubitemid 46809412)
20. DeBackey M, Glaser D: Patterns of atherosclerosis: Effect of risk factors on recurrence and survival - Analysis of 11,890 cases with more than 25-years follow-up. Am J Cardiol 85: 1045-1053, 2000
21. Parhami F, Garfinkel A, Demer LL: Role of lipids in osteoporosis. Arterioscler Thromb Vasc Biol 20: 2346-2348, 2000
22. Koh JM, Khang YH, Jung CH, Bae S, Kim DJ, Chung YE, Kim GS: Higher circulating hsCRP levels are associated with lower bone mineral density in healthy pre- and postmenopausal women: Evidence for a link between systemic inflammation and osteoporosis. Osteoporos Int 16: 1263-1271, 2005 (Pubitemid 41396955)
23. Braam LA, Hoeks APG, Brouns F, Hamulyák K, Gerichhausen MJ, Vermeer C: Beneficial effects of vitamins D and K on the elastic properties of the vessel wall in postmenopausal women: A follow-up study. Thromb Haemost 91: 373-380, 2004 (Pubitemid 38240185)
24. Gerdhem P, Obrant KJ: Effects of cigarette smoking on bone mass as assessed by dual-energy X-ray absorptiometry and ultrasound. Osteoporos Int 13: 932-936, 2002 (Pubitemid 36050270)
25. Mody N, Parhami F, Sarafian TA, Demer LL: Oxidative stress modulates osteoblastic differentiation of vascular and bone cells. Free Radic Biol Med 31: 509-519, 2001 (Pubitemid 32728438)
26. Hofbauer LC, Schoppet M: Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases. JAMA 292: 490-495, 2004
27. Collin-Osdoby P: Regulation of vascular calcification by osteoclast regulatory factors RANKL and osteoprotegerin. Circ Res 95: 1046-1057, 2004
28. Bucay N, Sarosi I, Dunstan CR, Morony S, Tarpley J, Capparelli C, Scully S, Tan HL, Xu W, Lacey DL, Boyle WJ, Simonet WS: Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev 12: 1260-1268, 1998 (Pubitemid 28213402)
29. Flore CE, Pennisi P, Ferro G, Ximenes B, Privitelli L, Mangiafico RA, Santoro F, Parisi N, Lombardo T: Altered osteoprotegerin/ RANKL ratio and low bone mineral density in celiac patients on long-term treatment with gluten-free diet. Horm Metab Res 38: 417-422, 2006 (Pubitemid 44055792)
30. Reynolds JL, Joannides AJ, Skepper JN, McNair R, Schurgers LJ, Proudfoot D, Jahnen-Dechent W, Weissberg PL, Shanahan CM: Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: A potential mechanism for accelerated vascular calcification in ESRD. J Am Soc Nephrol 15: 2857-2867, 2004 (Pubitemid 41103395)
31. Scatena M, Liaw L, Ghiachelli CM: Osteopontin: A multifunctional molecule regulating chronic inflammation and vascular disease. Arterioscler Thromb Vasc Biol 27: 2304-2309, 2007 (Pubitemid 350203943)
32. Lomashvili KA, Cobbs S, Hennigar RA, Hardcastle KI, O'Neill WC: Phosphate-induced vascular calcification: Role of pyrophosphate and osteopontin. J Am Soc Nephrol 15: 1392-1401, 2004 (Pubitemid 38679664)
33. Hermans MM, Brandenburg V, Ketteler M, Kooman JP, van der Sande FM, Gladziwa U, Rensma PL, Bartelet K, Konings CJ, Hoeks AP, Floege J, Leunissen KM: Study on the relationship of serum fetuin-A concentration with aortic stiffness in patients on dialysis. Nephrol Dial Transplant 21: 1293-1299, 2006
34. Huang JC, Sakata T, Pfleger LL, Bencsik M, Halloran BP, Bikle DD, Nissenson RA: PTH differentially regulates expression of RANKL and OPG. J Bone Miner Res 19: 234-244, 2004 (Pubitemid 38116737)
35. Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, Confavreux C, Dacquin R, Mee PJ, McKee MD, Jung DY, Zhang Z, Kim JK, Mauvais-Jarvis F, Ducy P, Karsenty G: Endocrine regulation of energy metabolism by the skeleton. Cell 130: 456-469, 2007 (Pubitemid 47208519)
36. Ferron M, Hinoi E, Karsenty G, Ducy P: Osteocalcin differentially regulates β-cells and adipocyte gene expression and affects the development of metabolic disease in wild-type mice. Proc Natl Acad Sci U S A 105: 5266-5270, 2008 (Pubitemid 351738545)
37. Richards JB, Valdes AM, Burling K, Perks UC, Spector TD: Serum adiponectin and bone mineral density in women. J Clin Endocrin Metab 92: 1517-1523, 2007 (Pubitemid 46556433)
38. Kanazawa I, Yamaguchi T, Yamamoto M, Yamauchi M, Kurioka S, Yano S, Sugimoto T. Serum osteocalcin is associated with glucose metabolism and atherosclerosis parameters in type 2 diabetes mellitus. J Clin Endocrin Metab. 2008; (ahead of print)
39. Oshima K, Nampei A, Matsuda M, Iwaki M, Fukuhara A, Hashimoto J, Yoshikawa H, Shimomura I: Adiponectin increases bone mass by suppressing osteoclasts and activating osteoblasts. Biochem Biophys Res Commun 331: 520-526, 2005 (Pubitemid 40602668)
40. Luo XH, Guo LJ, Yuan LQ, Xie H, Zhou HD, Wu XP, Liao EY: Adiponectin stimulates human osteoblast proliferation and differentiation via the MAPK signaling pathway. Exp Cell Res 309: 99-109, 2005 (Pubitemid 41191227)
41. Elefteriou F, Takeda S, Ebihara K, Magre J, Patano N, Kim CA, Ogawa Y, Liu X, Ware SM, Craigen WJ, Robert JJ, Vinson C, Nakao K, Capeau J, Karsenty G: Serum leptin level is a regulator of bone mass. PNAS 101: 3258-3263, 2004
42. Parhami F, Tintut Y, Ballard A, Fogelman AM, Demer LL: Leptin enhances the calcification of vascular cells: Artery wall as a target of leptin. Circ Res 88: 954-960, 2001 (Pubitemid 32441475)
43. Coen G, Ballanti P, Fischer MS, Balducci A, Calabria S, Colamarco L, Di Zazzo G, Lifrieri F, Manni M, Sardella D, Nofroni I, Bonucci E: Serum leptin in dialysis renal osteodystrophy. Am J Kidney Dis 42: 1036-1042, 2003 (Pubitemid 37322920)
44. Laroche M: Intraosseous circulation from physiology to disease. Joint Bone Spine 69: 262-269, 2002
45. Alagiakrishnan K, Juby A, Hanley D, Tymchak W, Sclater A: Role of vascular factors in osteoporosis. J Gerontol 4: 362-366, 2008
46. Griffith JF, Yeung DK, Tsang PH, Choi KC, Kwok TC, Ahuja AT, Leung KS, Leung PC: Compromised bone marrow perfusion in osteoporosis. J Bone Miner Res 23: 1068-1075, 2008