-
1
-
-
0034981177
-
The rate and extent of oral bioavailability versus the rate and extent of oral absorption:clarification and recommendation of terminology
-
Chiou WL. The rate and extent of oral bioavailability versus the rate and extent of oral absorption:clarification and recommendation of terminology. J Pharmacokinet Pharmacodyn 2001;28(1):3-6.
-
(2001)
J Pharmacokinet Pharmacodyn
, vol.28
, Issue.1
, pp. 3-6
-
-
Chiou, W.L.1
-
4
-
-
0025311288
-
Epithelial transport of drugs in cell culture. I:A model for studying the passive diffusion of drugs over intestinal absorptive(Caco-2) cells
-
Artursson P. Epithelial transport of drugs in cell culture. I:A model for studying the passive diffusion of drugs over intestinal absorptive(Caco-2) cells. J Pharm Sci 1990;79(6):476-482.
-
(1990)
J Pharm Sci
, vol.79
, Issue.6
, pp. 476-482
-
-
Artursson, P.1
-
5
-
-
0025329248
-
Epithelial transport of drugs in cell culture. II:Effect of extracellular calcium concentration on the paracellular transport of drugs of different lipophilicities across monolayers of intestinal epithelial(Caco-2) cells
-
Artursson P, Magnusson C. Epithelial transport of drugs in cell culture. II:Effect of extracellular calcium concentration on the paracellular transport of drugs of different lipophilicities across monolayers of intestinal epithelial(Caco-2) cells. J Pharm Sci 1990;79(7):595-600.
-
(1990)
J Pharm Sci
, vol.79
, Issue.7
, pp. 595-600
-
-
Artursson, P.1
Magnusson, C.2
-
6
-
-
0027312774
-
Selective paracellular permeability in two models of intestinal absorption:cultured monolayers of human intestinal epithelial cells and rat intestinal segments
-
Artursson P, Ungell AL, Lofroth JE. Selective paracellular permeability in two models of intestinal absorption:cultured monolayers of human intestinal epithelial cells and rat intestinal segments. Pharm Res 1993;10(8):1123-1129.
-
(1993)
Pharm Res
, vol.10
, Issue.8
, pp. 1123-1129
-
-
Artursson, P.1
Ungell, A.L.2
Lofroth, J.E.3
-
7
-
-
0028818676
-
The lack of effect of induced net fluid absorption on the in vivo permeability of terbutaline in the human jejunum
-
Fagerholm U, Borgstrom L, Ahrenstedt O, Lennernas H. The lack of effect of induced net fluid absorption on the in vivo permeability of terbutaline in the human jejunum. J Drug Target 1995;3(3):191-200.
-
(1995)
J Drug Target
, vol.3
, Issue.3
, pp. 191-200
-
-
Fagerholm, U.1
Borgstrom, L.2
Ahrenstedt, O.3
Lennernas, H.4
-
8
-
-
0033017677
-
Jejunal permeability in humans in vivo and rats in situ:investigation of molecular size selectivity and solvent drag
-
Fagerholm U, Nilsson D, Knutson L, Lennernas H. Jejunal permeability in humans in vivo and rats in situ:investigation of molecular size selectivity and solvent drag. Acta Physiol Scand 1999;165(3):315-324.
-
(1999)
Acta Physiol Scand
, vol.165
, Issue.3
, pp. 315-324
-
-
Fagerholm, U.1
Nilsson, D.2
Knutson, L.3
Lennernas, H.4
-
9
-
-
0028307188
-
Intestinal drug absorption during induced net water absorption in man;a mechanistic study using antipyrine, atenolol and enalaprilat
-
Lennernas H, Ahrenstedt O, Ungell AL. Intestinal drug absorption during induced net water absorption in man;a mechanistic study using antipyrine, atenolol and enalaprilat. Br J Clin Pharmacol 1994;37(6):589-596.
-
(1994)
Br J Clin Pharmacol
, vol.37
, Issue.6
, pp. 589-596
-
-
Lennernas, H.1
Ahrenstedt, O.2
Ungell, A.L.3
-
10
-
-
0001158366
-
Die Berechnung der Wasserstoffzahl des Blutes aus der freien und gebundenen Kohlensäure desselben und die Sauerstoffbindungen des Blutes als Funktion der Wasserstoffzahl
-
Hasselbalch K. Die Berechnung der Wasserstoffzahl des Blutes aus der freien und gebundenen Kohlensäure desselben und die Sauerstoffbindungen des Blutes als Funktion der Wasserstoffzahl. Biochemistry 1916;78:112.
-
(1916)
Biochemistry
, vol.78
, pp. 112
-
-
Hasselbalch, K.1
-
11
-
-
0030990091
-
The oligopeptide transporter(Pept-1) in human intestine:biology and function
-
Adibi SA. The oligopeptide transporter(Pept-1) in human intestine:biology and function. Gastroenterology 1997;113(1):332-340.
-
(1997)
Gastroenterology
, vol.113
, Issue.1
, pp. 332-340
-
-
Adibi, S.A.1
-
12
-
-
0029584879
-
Biology of membrane transport proteins
-
Sadee W, Drubbisch V, Amidon GL. Biology of membrane transport proteins. Pharm Res 1995;12(12):1823-1837.
-
(1995)
Pharm Res
, vol.12
, Issue.12
, pp. 1823-1837
-
-
Sadee, W.1
Drubbisch, V.2
Amidon, G.L.3
-
13
-
-
0036000312
-
A mechanistic approach to understanding the factors affecting drug absorption:a review of fundamentals
-
Martinez MN, Amidon GL. A mechanistic approach to understanding the factors affecting drug absorption:a review of fundamentals. J Clin Pharmacol 2002;42(6):620-643.
-
(2002)
J Clin Pharmacol
, vol.42
, Issue.6
, pp. 620-643
-
-
Martinez, M.N.1
Amidon, G.L.2
-
14
-
-
0035078138
-
Anatomical and physiological parameters affecting gastrointestinal absorption in humans and rats
-
DeSesso JM, Jacobson CF. Anatomical and physiological parameters affecting gastrointestinal absorption in humans and rats. Food Chem Toxicol 2001;39(3):209-228.
-
(2001)
Food Chem Toxicol
, vol.39
, Issue.3
, pp. 209-228
-
-
DeSesso, J.M.1
Jacobson, C.F.2
-
15
-
-
85052174441
-
-
[computer program]. Version 6.03;Amidon GL, Bermejo M. TSRL, Inc
-
Modern Biopharmaceutics. [computer program]. Version 6.03;Amidon GL, Bermejo M. TSRL, Inc; 2003.
-
(2003)
Modern Biopharmaceutics
-
-
-
16
-
-
0029055473
-
Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals
-
Kararli TT. Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals. Biopharm Drug Dispos 1995;16(5):351-380.
-
(1995)
Biopharm Drug Dispos
, vol.16
, Issue.5
, pp. 351-380
-
-
Kararli, T.T.1
-
17
-
-
0027374248
-
Gastrointestinal parameters that influence oral medications
-
Dressman JB, Bass P, Ritschel WA, Friend DR, Rubinstein A, Ziv E. Gastrointestinal parameters that influence oral medications. J Pharm Sci 1993;82(9):857-872.
-
(1993)
J Pharm Sci
, vol.82
, Issue.9
, pp. 857-872
-
-
Dressman, J.B.1
Bass, P.2
Ritschel, W.A.3
Friend, D.R.4
Rubinstein, A.5
Ziv, E.6
-
18
-
-
0033255551
-
Overview of membrane transport
-
Oh DM, Amidon GL. Overview of membrane transport. Pharm Biotechnol 1999;12:1-27.
-
(1999)
Pharm Biotechnol
, vol.12
, pp. 1-27
-
-
Oh, D.M.1
Amidon, G.L.2
-
19
-
-
0033254582
-
Drug transport and targeting. Intestinal transport
-
Oh DM, Han HK, Amidon GL. Drug transport and targeting. Intestinal transport. Pharm Biotechnol 1999;12:59-88.
-
(1999)
Pharm Biotechnol
, vol.12
, pp. 59-88
-
-
Oh, D.M.1
Han, H.K.2
Amidon, G.L.3
-
20
-
-
1442302325
-
Intestinal drug transporters:in vivo function and clinical importance
-
Kunta JR, Sinko PJ. Intestinal drug transporters:in vivo function and clinical importance. Curr Drug Metab 2004;5(1):109-124.
-
(2004)
Curr Drug Metab
, vol.5
, Issue.1
, pp. 109-124
-
-
Kunta, J.R.1
Sinko, P.J.2
-
21
-
-
0042690967
-
Transporters in the GI tract
-
Waterbeemd V-d, Lennernäs H, Pirtursson P, Eds Weinheim, Germany:Wiley-VCH
-
Shin HC, Landowski CD, Amidon GL. Transporters in the GI tract. In Waterbeemd V-d, Lennernäs H, Pirtursson P, Eds. Drug Bioavailability/Estimation of Solubility, Permeability and Absorption. Weinheim, Germany:Wiley-VCH; 2003.
-
(2003)
Drug Bioavailability/Estimation of Solubility, Permeability and Absorption
-
-
Shin, H.C.1
Landowski, C.D.2
Amidon, G.L.3
-
22
-
-
84966997026
-
Oral permeability predictions--from in silico to in vivo models
-
Bermejo M, Ruiz-Garcia A. Oral permeability predictions--from in silico to in vivo models. Business Briefing Pharma Tech 2002;175-180.
-
(2002)
Business Briefing Pharma Tech
, pp. 175-180
-
-
Bermejo, M.1
Ruiz-Garcia, A.2
-
23
-
-
0032872193
-
P aracellular drug transport across intestinal epithelia:influence of charge and induced water flux
-
Karlsson J, Ungell A, Grasjo J, Artursson P. P aracellular drug transport across intestinal epithelia:influence of charge and induced water flux. Eur J Pharm Sci 1999;9(1):47-56.
-
(1999)
Eur J Pharm Sci
, vol.9
, Issue.1
, pp. 47-56
-
-
Karlsson, J.1
Ungell, A.2
Grasjo, J.3
Artursson, P.4
-
24
-
-
0030792730
-
Estimation of the relative contribution of the transcellular and paracellular pathway to the transport of passively absorbed drugs in the Caco-2 cell culture model
-
Pade V, Stavchansky S. Estimation of the relative contribution of the transcellular and paracellular pathway to the transport of passively absorbed drugs in the Caco-2 cell culture model. Pharm Res 1997;14(9):1210-1215.
-
(1997)
Pharm Res
, vol.14
, Issue.9
, pp. 1210-1215
-
-
Pade, V.1
Stavchansky, S.2
-
25
-
-
0032905293
-
Validation of a biophysical drug absorption model by the PATQSAR system
-
Bermejo M, Merino V, Garrigues TM, et al. Validation of a biophysical drug absorption model by the PATQSAR system. J Pharm Sci 1999;88(4):398-405.
-
(1999)
J Pharm Sci
, vol.88
, Issue.4
, pp. 398-405
-
-
Bermejo, M.1
Merino, V.2
Garrigues, T.M.3
-
26
-
-
0022000211
-
The absorption of beta-adrenoceptor antagonists in rat in-situ small intestine;the effect of lipophilicity
-
Taylor DC, Pownall R, Burke W. The absorption of beta-adrenoceptor antagonists in rat in-situ small intestine;the effect of lipophilicity. J Pharm Pharmacol 1985; 37(4):280-283.
-
(1985)
J Pharm Pharmacol
, vol.37
, Issue.4
, pp. 280-283
-
-
Taylor, D.C.1
Pownall, R.2
Burke, W.3
-
27
-
-
0346040093
-
The composite solubility versus pH profile and its role in intestinal absorption prediction
-
Hendriksen BA, Felix MV, Bolger MB. The composite solubility versus pH profile and its role in intestinal absorption prediction. AAPS PharmSci 2003;5(1):E4.
-
(2003)
AAPS PharmSci
, vol.5
, Issue.1
, pp. E4
-
-
Hendriksen, B.A.1
Felix, M.V.2
Bolger, M.B.3
-
28
-
-
0029557644
-
Does fluid flow across the intestinal mucosa affect quantitative oral drug absorption? Is it time for a reevaluation?
-
Lennernas H. Does fluid flow across the intestinal mucosa affect quantitative oral drug absorption? Is it time for a reevaluation? Pharm Res 1995;12(11):1573-1582.
-
(1995)
Pharm Res
, vol.12
, Issue.11
, pp. 1573-1582
-
-
Lennernas, H.1
-
29
-
-
0023881473
-
Physiological measurement of luminal stirring in perfused rat jejunum
-
Anderson BW, Levine AS, Levitt DG, Kneip JM, Levitt MD. Physiological measurement of luminal stirring in perfused rat jejunum. Am J Physiol 1988;254(6 Pt 1):G843-G848.
-
(1988)
Am J Physiol
, vol.254
, Issue.6
, pp. G843-G848
-
-
Anderson, B.W.1
Levine, A.S.2
Levitt, D.G.3
Kneip, J.M.4
Levitt, M.D.5
-
30
-
-
0025196085
-
Physiological measurements of luminal stirring in the dog and human small bowel
-
Levitt MD, Furne JK, Strocchi A, Anderson BW, Levitt DG. Physiological measurements of luminal stirring in the dog and human small bowel. J Clin Invest 1990;86(5):1540-1547.
-
(1990)
J Clin Invest
, vol.86
, Issue.5
, pp. 1540-1547
-
-
Levitt, M.D.1
Furne, J.K.2
Strocchi, A.3
Anderson, B.W.4
Levitt, D.G.5
-
31
-
-
0029782485
-
Carrier-mediated intestinal transport of drugs
-
Tsuji A, Tamai I. Carrier-mediated intestinal transport of drugs. Pharm Res 1996;13(7):963-977.
-
(1996)
Pharm Res
, vol.13
, Issue.7
, pp. 963-977
-
-
Tsuji, A.1
Tamai, I.2
-
32
-
-
2442719906
-
Unmasking the dynamic interplay between efflux transporters and metabolic enzymes
-
Benet LZ, Cummins CL, Wu CY. Unmasking the dynamic interplay between efflux transporters and metabolic enzymes. Int J Pharm 2004;277(1-2):3-9.
-
(2004)
Int J Pharm
, vol.277
, Issue.1-2
, pp. 3-9
-
-
Benet, L.Z.1
Cummins, C.L.2
Wu, C.Y.3
-
33
-
-
14544304168
-
Efflux transporters and their clinical relevance
-
Fischer V, Einolf HJ, Cohen D. Efflux transporters and their clinical relevance. Mini Rev Med Chem 2005;5(2):183-195.
-
(2005)
Mini Rev Med Chem
, vol.5
, Issue.2
, pp. 183-195
-
-
Fischer, V.1
Einolf, H.J.2
Cohen, D.3
-
34
-
-
0035478718
-
Intestinal drug efflux:formulation and food effects
-
Wagner D, Spahn-Langguth H, Hanafy A, Koggel A, Langguth P. Intestinal drug efflux:formulation and food effects. Adv Drug Deliv Rev 2001;50(Suppl 1):S13-S31.
-
(2001)
Adv Drug Deliv Rev
, vol.50
, pp. S13-S31
-
-
Wagner, D.1
Spahn-Langguth, H.2
Hanafy, A.3
Koggel, A.4
Langguth, P.5
-
35
-
-
0033739725
-
Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine
-
Suzuki H, Sugiyama Y. Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine. Eur J Pharm Sci 2000;12(1):3-12.
-
(2000)
Eur J Pharm Sci
, vol.12
, Issue.1
, pp. 3-12
-
-
Suzuki, H.1
Sugiyama, Y.2
-
36
-
-
0036481691
-
G astrointestinal transit and drug absorption
-
Kimura T, Higaki K. G astrointestinal transit and drug absorption. Biol Pharm Bull 2002;25(2):149-164.
-
(2002)
Biol Pharm Bull
, vol.25
, Issue.2
, pp. 149-164
-
-
Kimura, T.1
Higaki, K.2
-
37
-
-
0025952084
-
Developments in buccal drug delivery
-
de Vries ME, Bodde HE, Verhoef JC, Junginger HE. Developments in buccal drug delivery. Crit Rev Ther Drug Carrier Syst 1991;8(3):271-303.
-
(1991)
Crit Rev Ther Drug Carrier Syst
, vol.8
, Issue.3
, pp. 271-303
-
-
de Vries, M.E.1
Bodde, H.E.2
Verhoef, J.C.3
Junginger, H.E.4
-
38
-
-
0025794254
-
The permeability of oral mucosa
-
Squier CA. The permeability of oral mucosa. Crit Rev Oral Biol Med 1991;2(1):13-32.
-
(1991)
Crit Rev Oral Biol Med
, vol.2
, Issue.1
, pp. 13-32
-
-
Squier, C.A.1
-
39
-
-
0024110674
-
Hydrogels for buccal drug delivery:properties relevant for muco-adhesion
-
de Vries ME, Bodde HE, Busscher HJ, Junginger HE. Hydrogels for buccal drug delivery:properties relevant for muco-adhesion. J Biomed Mater Res 1988;22(11):1023-1032.
-
(1988)
J Biomed Mater Res
, vol.22
, Issue.11
, pp. 1023-1032
-
-
de Vries, M.E.1
Bodde, H.E.2
Busscher, H.J.3
Junginger, H.E.4
-
40
-
-
0031597891
-
Buccal mucosa as a route for systemic drug delivery:a review
-
Shojaei AH. Buccal mucosa as a route for systemic drug delivery:a review. J Pharm Pharm Sci 1998;1(1):15-30.
-
(1998)
J Pharm Pharm Sci
, vol.1
, Issue.1
, pp. 15-30
-
-
Shojaei, A.H.1
-
41
-
-
0026564618
-
Drug delivery via the mucous membranes of the oral cavity
-
Harris D, Robinson JR. Drug delivery via the mucous membranes of the oral cavity. J Pharm Sci 1992;81(1):1-10.
-
(1992)
J Pharm Sci
, vol.81
, Issue.1
, pp. 1-10
-
-
Harris, D.1
Robinson, J.R.2
-
42
-
-
0017033158
-
The in vitro permeability of skin and buccal mucosa to selected drugs and tritiated water
-
Galey WR, Lonsdale HK, Nacht S. The in vitro permeability of skin and buccal mucosa to selected drugs and tritiated water. J Invest Dermatol 1976;67(6):713-717.
-
(1976)
J Invest Dermatol
, vol.67
, Issue.6
, pp. 713-717
-
-
Galey, W.R.1
Lonsdale, H.K.2
Nacht, S.3
-
43
-
-
0026045125
-
Cellular and molecular basis of barrier function in oral epithelium
-
Wertz PW, Squier CA. Cellular and molecular basis of barrier function in oral epithelium. Crit Rev Ther Drug Carrier Syst 1991;8(3):237-269.
-
(1991)
Crit Rev Ther Drug Carrier Syst
, vol.8
, Issue.3
, pp. 237-269
-
-
Wertz, P.W.1
Squier, C.A.2
-
44
-
-
0025976524
-
Lipid content and water permeability of skin and oral mucosa
-
Squier CA, Cox P, Wertz PW. Lipid content and water permeability of skin and oral mucosa. J Invest Dermatol 1991;96(1):123-126.
-
(1991)
J Invest Dermatol
, vol.96
, Issue.1
, pp. 123-126
-
-
Squier, C.A.1
Cox, P.2
Wertz, P.W.3
-
45
-
-
0025246336
-
Effects of first-pass metabolism on metabolite mean residence time determination after oral administration of parent drug
-
Chan KK, Gibaldi M. Effects of first-pass metabolism on metabolite mean residence time determination after oral administration of parent drug. Pharm Res 1990;7(1):59-63.
-
(1990)
Pharm Res
, vol.7
, Issue.1
, pp. 59-63
-
-
Chan, K.K.1
Gibaldi, M.2
-
46
-
-
0028950358
-
Buccal absorption of fentanyl is pH-dependent in dogs
-
Streisand JB, Zhang J, Niu S, McJames S, Natte R, Pace NL. Buccal absorption of fentanyl is pH-dependent in dogs. Anesthesiology 1995;82(3):759-764.
-
(1995)
Anesthesiology
, vol.82
, Issue.3
, pp. 759-764
-
-
Streisand, J.B.1
Zhang, J.2
Niu, S.3
McJames, S.4
Natte, R.5
Pace, N.L.6
-
48
-
-
0026719630
-
Existence of specialized absorption mechanism for cephadroxyl, an aminocephalosporin antibiotic, in the human oral cavity
-
Kurosaki YNH, Terao K, Nakayama T, Kimura T. Existence of specialized absorption mechanism for cephadroxyl, an aminocephalosporin antibiotic, in the human oral cavity. Int J Pharm 1992;82:165-169.
-
(1992)
Int J Pharm
, vol.82
, pp. 165-169
-
-
Kurosaki, Y.N.H.1
Terao, K.2
Nakayama, T.3
Kimura, T.4
-
49
-
-
0023520197
-
Rectal administration of antiepileptic drugs in children
-
Graves NM, Kriel RL. Rectal administration of antiepileptic drugs in children. Pediatr Neurol 1987;3(6):321-326.
-
(1987)
Pediatr Neurol
, vol.3
, Issue.6
, pp. 321-326
-
-
Graves, N.M.1
Kriel, R.L.2
-
50
-
-
0025294915
-
Preanesthetic medication with rectal midazolam in children undergoing dental extractions
-
discussion 797
-
Roelofse JA, van der Bijl P, Stegmann DH, Hartshorne JE. Preanesthetic medication with rectal midazolam in children undergoing dental extractions. J Oral Maxillofac Surg 1990;48(8):791-797;discussion 797.
-
(1990)
J Oral Maxillofac Surg
, vol.48
, Issue.8
, pp. 791-797
-
-
Roelofse, J.A.1
van der Bijl, P.2
Stegmann, D.H.3
Hartshorne, J.E.4
-
51
-
-
0027159526
-
Plasma concentrations of midazolam after i.v., nasal or rectal administration in children
-
Malinovsky JM, Lejus C, Servin F, et al. Plasma concentrations of midazolam after i.v., nasal or rectal administration in children. Br J Anaesth 1993;70(6):617-620.
-
(1993)
Br J Anaesth
, vol.70
, Issue.6
, pp. 617-620
-
-
Malinovsky, J.M.1
Lejus, C.2
Servin, F.3
-
52
-
-
1842442330
-
The rectal absorption of opioids. In Benedetti C, Chapman CR, Giron G, Eds
-
Philadelphia:Lippincott-Raven
-
Hanning CD. The rectal absorption of opioids. In Benedetti C, Chapman CR, Giron G, Eds. Advances in Pain Research and Therapy. Philadelphia:Lippincott-Raven; 1990; 14:259-268.
-
(1990)
Advances in Pain Research and Therapy
, vol.14
, pp. 259-268
-
-
Hanning, C.D.1
-
53
-
-
0030857927
-
American Academy of Pediatrics. Committee on Drugs
-
Alternative routes of drug administration-advantages and disadvantages(subject review). American Academy of Pediatrics. Committee on Drugs. Pediatrics 1997;100(1):143-152.
-
(1997)
Pediatrics
, vol.100
, Issue.1
, pp. 143-152
-
-
-
54
-
-
0025893088
-
Pharmacokinetics of rectal drug administration. Part II. Clinical applications of peripherally acting drugs, and conclusions
-
van Hoogdalem EJ, de Boer AG, Breimer DD. Pharmacokinetics of rectal drug administration. Part II. Clinical applications of peripherally acting drugs, and conclusions. Clin Pharmacokinet 1991;21(2):110-128.
-
(1991)
Clin Pharmacokinet
, vol.21
, Issue.2
, pp. 110-128
-
-
Van Hoogdalem, E.J.1
De Boer, A.G.2
Breimer, D.D.3
-
55
-
-
0023227952
-
Giving drugs per rectum for systemic effect
-
Choonara IA. Giving drugs per rectum for systemic effect. Arch Dis Child 1987; 62(8):771-772.
-
(1987)
Arch Dis Child
, vol.62
, Issue.8
, pp. 771-772
-
-
Choonara, I.A.1
-
56
-
-
0025152984
-
Rectal methohexital:concentration and length of the rectal catheters
-
Khalil SN, Florence FB, Van den Nieuwenhuyzen MC, Wu AH, Stanley TH. Rectal methohexital:concentration and length of the rectal catheters. Anesth Analg 1990; 70(6):645-649.
-
(1990)
Anesth Analg
, vol.70
, Issue.6
, pp. 645-649
-
-
Khalil, S.N.1
Florence, F.B.2
Van den Nieuwenhuyzen, M.C.3
Wu, A.H.4
Stanley, T.H.5
-
57
-
-
0025778611
-
Pharmacokinetics of rectal drug administration. Part I. General considerations and clinical applications of centrally acting drugs
-
van Hoogdalem E, de Boer AG, Breimer DD. Pharmacokinetics of rectal drug administration. Part I. General considerations and clinical applications of centrally acting drugs. Clin Pharmacokinet 1991;21(1):11-26.
-
(1991)
Clin Pharmacokinet
, vol.21
, Issue.1
, pp. 11-26
-
-
Van Hoogdalem, E.1
De Boer, A.G.2
Breimer, D.D.3
-
58
-
-
0023758679
-
Comparison of two and ten percent rectal methohexitone for induction of anaesthesia in children
-
Forbes RB, Vandewalker GE. Comparison of two and ten percent rectal methohexitone for induction of anaesthesia in children. Can J Anaesth 1988;35(4):345-349.
-
(1988)
Can J Anaesth
, vol.35
, Issue.4
, pp. 345-349
-
-
Forbes, R.B.1
Vandewalker, G.E.2
-
59
-
-
0022534991
-
The effect of rectal pH values on the absorption of methohexital
-
Jantzen JP, Erdmann K, Witton PK, Klein AM. The effect of rectal pH values on the absorption of methohexital. Anaesthesist 1986;35(8):496-499.
-
(1986)
Anaesthesist
, vol.35
, Issue.8
, pp. 496-499
-
-
Jantzen, J.P.1
Erdmann, K.2
Witton, P.K.3
Klein, A.M.4
-
60
-
-
0024853750
-
Rectal pH In children
-
Jantzen JP, Tzanova I, Witton PK, Klein AM. Rectal pH In children. Can J Anaesth 1989;36(6):665-667.
-
(1989)
Can J Anaesth
, vol.36
, Issue.6
, pp. 665-667
-
-
Jantzen, J.P.1
Tzanova, I.2
Witton, P.K.3
Klein, A.M.4
-
61
-
-
0020961251
-
Measurements of pulmonary epithelial permeability in vivo
-
Effros RM, Mason GR. Measurements of pulmonary epithelial permeability in vivo. Am Rev Respir Dis 1983;127(5 Pt 2):S59-S65.
-
(1983)
Am Rev Respir Dis
, vol.127
, Issue.5
, pp. S59-S65
-
-
Effros, R.M.1
Mason, G.R.2
-
62
-
-
0037107001
-
Permeability issues in nasal drug delivery
-
Arora P, Sharma S, Garg S. Permeability issues in nasal drug delivery. Drug Discov Today 2002;7(18):967-975.
-
(2002)
Drug Discov Today
, vol.7
, Issue.18
, pp. 967-975
-
-
Arora, P.1
Sharma, S.2
Garg, S.3
-
63
-
-
3542998669
-
Nasal route and drug delivery systems
-
Turker S, Onur E, Ozer Y. Nasal route and drug delivery systems. P harm World Sci 2004;26(3):137-142.
-
(2004)
P harm World Sci
, vol.26
, Issue.3
, pp. 137-142
-
-
Turker, S.1
Onur, E.2
Ozer, Y.3
-
64
-
-
0036896831
-
Nasal drug delivery:new developments and strategies
-
Illum L. Nasal drug delivery:new developments and strategies. Drug Discov Today 2002;7(23):1184-1189.
-
(2002)
Drug Discov Today
, vol.7
, Issue.23
, pp. 1184-1189
-
-
Illum, L.1
-
65
-
-
0037459005
-
Nasal drug delivery-possibilities, problems and solutions
-
Illum L. Nasal drug delivery-possibilities, problems and solutions. J Control Release 2003;87(1-3):187-198.
-
(2003)
J Control Release
, vol.87
, Issue.1-3
, pp. 187-198
-
-
Illum, L.1
-
66
-
-
0035940314
-
Chitosan as a novel nasal delivery system for vaccines
-
Illum L, Jabbal-Gill I, Hinchcliffe M, Fisher AN, Davis SS. Chitosan as a novel nasal delivery system for vaccines. Adv Drug Deliv Rev 2001;51(1-3):81-96.
-
(2001)
Adv Drug Deliv Rev
, vol.51
, Issue.1-3
, pp. 81-96
-
-
Illum, L.1
Jabbal-Gill, I.2
Hinchcliffe, M.3
Fisher, A.N.4
Davis, S.S.5
-
67
-
-
1842850702
-
The influence of absorption enhancers on nasal absorption of acyclovir
-
Chavanpatil MD, Vavia PR. The influence of absorption enhancers on nasal absorption of acyclovir. Eur J Pharm Biopharm 2004;57(3):483-487.
-
(2004)
Eur J Pharm Biopharm
, vol.57
, Issue.3
, pp. 483-487
-
-
Chavanpatil, M.D.1
Vavia, P.R.2
-
68
-
-
0242288486
-
Absorption enhancers for nasal drug delivery
-
Davis SS, Illum L. Absorption enhancers for nasal drug delivery. Clin Pharmacokinet 2003;42(13):1107-1128.
-
(2003)
Clin Pharmacokinet
, vol.42
, Issue.13
, pp. 1107-1128
-
-
Davis, S.S.1
Illum, L.2
-
70
-
-
18444398943
-
Advances in the cell biology of transport via the inner blood-retinal barrier:establishment of cell lines and transport functions
-
Hosoya K, Tomi M. Advances in the cell biology of transport via the inner blood-retinal barrier:establishment of cell lines and transport functions. Biol Pharm Bull 2005;28(1):1-8.
-
(2005)
Biol Pharm Bull
, vol.28
, Issue.1
, pp. 1-8
-
-
Hosoya, K.1
Tomi, M.2
-
71
-
-
20444386592
-
Human cornea construct HCC-an alternative for in vitro permeation studies? A comparison with human donor corneas
-
Reichl S, Dohring S, Bednarz J, Muller-Goymann CC. Human cornea construct HCC-an alternative for in vitro permeation studies? A comparison with human donor corneas. Eur J Pharm Biopharm 2005;60(2):305-308.
-
(2005)
Eur J Pharm Biopharm
, vol.60
, Issue.2
, pp. 305-308
-
-
Reichl, S.1
Dohring, S.2
Bednarz, J.3
Muller-Goymann, C.C.4
-
72
-
-
0033998781
-
Skin permeation of testosterone and its ester derivatives in rats
-
Kim MK, Lee CH, Kim DD. Skin permeation of testosterone and its ester derivatives in rats. J Pharm Pharmacol 2000;52(4):369-375.
-
(2000)
J Pharm Pharmacol
, vol.52
, Issue.4
, pp. 369-375
-
-
Kim, M.K.1
Lee, C.H.2
Kim, D.D.3
-
73
-
-
0034691642
-
Comparative enhancer effects of Span20 with Tween20 and Azone on the in vitro percutaneous penetration of compounds with different lipophilicities
-
Lopez A, Llinares F, Cortell C, Herraez M. Comparative enhancer effects of Span20 with Tween20 and Azone on the in vitro percutaneous penetration of compounds with different lipophilicities. Int J Pharm 2000;202(1-2):133-140.
-
(2000)
Int J Pharm
, vol.202
, Issue.1-2
, pp. 133-140
-
-
Lopez, A.1
Llinares, F.2
Cortell, C.3
Herraez, M.4
-
75
-
-
0031924387
-
Transdermal drug delivery. Clinical aspects
-
Kalia YN, Merino V, Guy RH. Transdermal drug delivery. Clinical aspects. Dermatol Clin 1998;16(2):289-299.
-
(1998)
Dermatol Clin
, vol.16
, Issue.2
, pp. 289-299
-
-
Kalia, Y.N.1
Merino, V.2
Guy, R.H.3
-
76
-
-
0344643413
-
Vaginal ring delivery of hormone replacement therapy-a review
-
Dezarnaulds G, Fraser IS. Vaginal ring delivery of hormone replacement therapy-a review. Expert Opin Pharmacother 2003;4(2):201-212.
-
(2003)
Expert Opin Pharmacother
, vol.4
, Issue.2
, pp. 201-212
-
-
Dezarnaulds, G.1
Fraser, I.S.2
-
77
-
-
0031734451
-
Role of stromal and epithelial estrogen receptors in vaginal epithelial proliferation, stratification, and cornification
-
Buchanan DL, Kurita T, Taylor JA, Lubahn DB, Cunha GR, Cooke PS. Role of stromal and epithelial estrogen receptors in vaginal epithelial proliferation, stratification, and cornification. Endocrinology 1998;139(10):4345-4352.
-
(1998)
Endocrinology
, vol.139
, Issue.10
, pp. 4345-4352
-
-
Buchanan, D.L.1
Kurita, T.2
Taylor, J.A.3
Lubahn, D.B.4
Cunha, G.R.5
Cooke, P.S.6
-
79
-
-
3242796693
-
Why consider vaginal drug administration?
-
Alexander NJ, Baker E, Kaptein M, Karck U, Miller L, Zampaglione E. Why consider vaginal drug administration? Fertil Steril 2004;82(1):1-12.
-
(2004)
Fertil Steril
, vol.82
, Issue.1
, pp. 1-12
-
-
Alexander, N.J.1
Baker, E.2
Kaptein, M.3
Karck, U.4
Miller, L.5
Zampaglione, E.6
-
80
-
-
14844314490
-
The vagina as a route for systemic drug delivery
-
Hussain A, Ahsan F. The vagina as a route for systemic drug delivery. J Control Release 2005;103(2):301-313.
-
(2005)
J Control Release
, vol.103
, Issue.2
, pp. 301-313
-
-
Hussain, A.1
Ahsan, F.2
-
81
-
-
0043028154
-
Comparative in vitro permeability of human vaginal, small intestinal and colonic mucosa
-
van der Bijl P, Van Eyk AD. Comparative in vitro permeability of human vaginal, small intestinal and colonic mucosa. Int J Pharm 2003;261(1-2):147-152.
-
(2003)
Int J Pharm
, vol.261
, Issue.1-2
, pp. 147-152
-
-
Van der Bijl, P.1
Van Eyk, A.D.2
-
82
-
-
3242742302
-
Needle-Free and Auto Injectors-Management Forum Conference. An update on technology and application. 23-24 Feb 2004, London, UK
-
Furness G. Needle-Free and Auto Injectors-Management Forum Conference. An update on technology and application. 23-24 Feb 2004, London, UK. IDrugs 2004;7(4):329-330.
-
(2004)
IDrugs
, vol.7
, Issue.4
, pp. 329-330
-
-
Furness, G.1
-
83
-
-
85052183150
-
Going from needles to needle-free injectables
-
Ajmani D. Going from needles to needle-free injectables. Drug Deliv Technol 2004; http://www.drugdeliverytech.com/cgi-bin/articles.cgi?idArticle=318
-
(2004)
Drug Deliv Technol
-
-
Ajmani, D.1
-
85
-
-
0031913402
-
Dissolution testing as a prognostic tool for oral drug absorption:immediate release dosage forms
-
Dressman JB, Amidon GL, Reppas C, Shah VP. Dissolution testing as a prognostic tool for oral drug absorption:immediate release dosage forms. Pharm Res 1998;15(1):11-22.
-
(1998)
Pharm Res
, vol.15
, Issue.1
, pp. 11-22
-
-
Dressman, J.B.1
Amidon, G.L.2
Reppas, C.3
Shah, V.P.4
-
86
-
-
0344286485
-
Cyclodextrins in ophthalmic drug delivery
-
Loftssona T, Jarvinen T. Cyclodextrins in ophthalmic drug delivery. Adv Drug Deliv Rev 1999;36(1):59-79.
-
(1999)
Adv Drug Deliv Rev
, vol.36
, Issue.1
, pp. 59-79
-
-
Loftssona, T.1
Jarvinen, T.2
-
87
-
-
0034807548
-
Transport of peptidomimetic thrombin inhibitors with a 3-amidino-phenylalanine structure:permeability and efflux mechanism in monolayers of a human intestinal cell line(Caco-2)
-
Kamm W, Hauptmann J, Behrens I, et al. Transport of peptidomimetic thrombin inhibitors with a 3-amidino-phenylalanine structure:permeability and efflux mechanism in monolayers of a human intestinal cell line(Caco-2). Pharm Res 2001;18(8):1110-1118.
-
(2001)
Pharm Res
, vol.18
, Issue.8
, pp. 1110-1118
-
-
Kamm, W.1
Hauptmann, J.2
Behrens, I.3
-
88
-
-
0032729578
-
Prediction of the intestinal absorption of endothelin receptor antagonists using three theoretical methods of increasing complexity
-
Stenberg P, Luthman K, Ellens H, et al. Prediction of the intestinal absorption of endothelin receptor antagonists using three theoretical methods of increasing complexity. Pharm Res 1999;16(10):1520-1526.
-
(1999)
Pharm Res
, vol.16
, Issue.10
, pp. 1520-1526
-
-
Stenberg, P.1
Luthman, K.2
Ellens, H.3
-
89
-
-
0023624652
-
Studies on the reliability of a bihyperbolic functional absorption model. II. Phenylalkylamines
-
Casabo VG, Nunez-Benito E, Martinez-Coscolla A, Miralles-Loyola E, Martin-Villodre A, Pla-Delfina JM. Studies on the reliability of a bihyperbolic functional absorption model. II. Phenylalkylamines. J Pharmacokinet Biopharm 1987;15(6):633-643.
-
(1987)
J Pharmacokinet Biopharm
, vol.15
, Issue.6
, pp. 633-643
-
-
Casabo, V.G.1
Nunez-Benito, E.2
Martinez-Coscolla, A.3
Miralles-Loyola, E.4
Martin-Villodre, A.5
Pla-Delfina, J.M.6
-
90
-
-
0031413597
-
Improved prediction of in vivo peroral absorption from in vitro intestinal permeability using an internal standard to control for intra-and inter-rat variability
-
Dowty ME, Dietsch CR. Improved prediction of in vivo peroral absorption from in vitro intestinal permeability using an internal standard to control for intra-and inter-rat variability. Pharm Res 1997;14(12):1792-1797.
-
(1997)
Pharm Res
, vol.14
, Issue.12
, pp. 1792-1797
-
-
Dowty, M.E.1
Dietsch, C.R.2
-
91
-
-
0032190504
-
S hapes of membrane permeability-lipophilicity curves:extension of theoretical models with an aqueous pore pathway
-
Camenisch G, Folkers G, van de Waterbeemd H. S hapes of membrane permeability-lipophilicity curves:extension of theoretical models with an aqueous pore pathway. Eur J Pharm Sci 1998;6(4):325-329.
-
(1998)
Eur J Pharm Sci
, vol.6
, Issue.4
, pp. 325-329
-
-
Camenisch, G.1
Folkers, G.2
Van De Waterbeemd, H.3
-
92
-
-
0032979004
-
Theoretical calculation and prediction of intestinal absorption of drugs in humans using MolSurf parametrization and PLS statistics
-
Norinder U, Osterberg T, Artursson P. Theoretical calculation and prediction of intestinal absorption of drugs in humans using MolSurf parametrization and PLS statistics. Eur J Pharm Sci 1999;8(1):49-56.
-
(1999)
Eur J Pharm Sci
, vol.8
, Issue.1
, pp. 49-56
-
-
Norinder, U.1
Osterberg, T.2
Artursson, P.3
-
93
-
-
0030030608
-
Correlation of drug absorption with molecular surface properties
-
Palm K, Luthman K, Ungell AL, Strandlund G, Artursson P. Correlation of drug absorption with molecular surface properties. J Pharm Sci 1996;85(1):32-39.
-
(1996)
J Pharm Sci
, vol.85
, Issue.1
, pp. 32-39
-
-
Palm, K.1
Luthman, K.2
Ungell, A.L.3
Strandlund, G.4
Artursson, P.5
-
94
-
-
0032811868
-
Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 2. Prediction of blood-brain barrier penetration
-
Clark DE. Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 2. Prediction of blood-brain barrier penetration. J Pharm Sci 1999;88(8):815-821.
-
(1999)
J Pharm Sci
, vol.88
, Issue.8
, pp. 815-821
-
-
Clark, D.E.1
-
95
-
-
0032795192
-
Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 1. Prediction of intestinal absorption
-
Clark DE. Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 1. Prediction of intestinal absorption. J Pharm Sci 1999;88(8):807-814.
-
(1999)
J Pharm Sci
, vol.88
, Issue.8
, pp. 807-814
-
-
Clark, D.E.1
-
96
-
-
0026917279
-
Percutaneous absorption and age. Implications for therapy
-
Roskos KV, Maibach HI. Percutaneous absorption and age. Implications for therapy. Drugs Aging 1992;2(5):432-449.
-
(1992)
Drugs Aging
, vol.2
, Issue.5
, pp. 432-449
-
-
Roskos, K.V.1
Maibach, H.I.2
-
97
-
-
0027410525
-
Racial differences in the in vivo percutaneous absorption of some organic compounds:a comparison between black, Caucasian and Asian subjects
-
Lotte C, Wester RC, Rougier A, Maibach HI. Racial differences in the in vivo percutaneous absorption of some organic compounds:a comparison between black, Caucasian and Asian subjects. Arch Dermatol Res 1993;284(8):456-459.
-
(1993)
Arch Dermatol Res
, vol.284
, Issue.8
, pp. 456-459
-
-
Lotte, C.1
Wester, R.C.2
Rougier, A.3
Maibach, H.I.4
-
98
-
-
0024403861
-
Cutaneous responses to topical methyl nicotinate in black, Oriental, and Caucasian subjects
-
Gean CJ, Tur E, Maibach HI, Guy RH. Cutaneous responses to topical methyl nicotinate in black, Oriental, and Caucasian subjects. Arch Dermatol Res 1989;281(2):95-98.
-
(1989)
Arch Dermatol Res
, vol.281
, Issue.2
, pp. 95-98
-
-
Gean, C.J.1
Tur, E.2
Maibach, H.I.3
Guy, R.H.4
-
99
-
-
0027368932
-
In vivo evaluation of the stratum corneum barrier function in blacks, Caucasians and Asians with two noninvasive methods
-
Kompaore F, Marty JP, Dupont C. In vivo evaluation of the stratum corneum barrier function in blacks, Caucasians and Asians with two noninvasive methods. Skin Pharmacol 1993;6(3):200-207.
-
(1993)
Skin Pharmacol
, vol.6
, Issue.3
, pp. 200-207
-
-
Kompaore, F.1
Marty, J.P.2
Dupont, C.3
-
100
-
-
0034820963
-
Effect of barrier disruption by acetone treatment on the permeability of compounds with various lipophilicities:implications for the permeability of compromised skin
-
Tsai JC, Sheu HM, Hung PL, Cheng CL. Effect of barrier disruption by acetone treatment on the permeability of compounds with various lipophilicities:implications for the permeability of compromised skin. J Pharm Sci 2001;90(9):1242-1254.
-
(2001)
J Pharm Sci
, vol.90
, Issue.9
, pp. 1242-1254
-
-
Tsai, J.C.1
Sheu, H.M.2
Hung, P.L.3
Cheng, C.L.4
-
101
-
-
0344874651
-
Increased permeability of psoriatic skin to the protein, plasminogen activator inhibitor 2
-
Gould AR, Sharp PJ, Smith DR, et al. Increased permeability of psoriatic skin to the protein, plasminogen activator inhibitor 2. Arch Dermatol Res 2003;295(6):249-254.
-
(2003)
Arch Dermatol Res
, vol.295
, Issue.6
, pp. 249-254
-
-
Gould, A.R.1
Sharp, P.J.2
Smith, D.R.3
|