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Volumn 14, Issue 12, 1997, Pages 1792-1797
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Improved prediction of in vivo peroral absorption from in vitro intestinal permeability using an internal standard to control for intra- and inter-rat variability
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Author keywords
In vitro intestinal permeability; In vitro in vivo correlation; In vivo mass balance; Peroral absorption; Rat; Ussing chamber
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Indexed keywords
APRACLONIDINE;
BISPHOSPHONIC ACID DERIVATIVE;
BRIMONIDINE;
CAFFEINE;
CLONIDINE;
HYDROCORTISONE;
HYDROXAMIC ACID DERIVATIVE;
IMIDAZOLINE DERIVATIVE;
MACROGOL;
MACROGOL 4000;
MACROGOL 900;
MANNITOL;
OXYMETAZOLINE;
PROGESTERONE;
SALICYLIC ACID;
UNCLASSIFIED DRUG;
ANIMAL TISSUE;
ARTICLE;
CALCULATION;
DRUG ABSORPTION;
DRUG BIOAVAILABILITY;
IN VITRO STUDY;
IN VIVO STUDY;
INTESTINE ABSORPTION;
INTESTINE MUCOSA PERMEABILITY;
INTRAVENOUS DRUG ADMINISTRATION;
MALE;
NONHUMAN;
ORAL DRUG ADMINISTRATION;
PREDICTION;
PRIORITY JOURNAL;
RAT;
STANDARD;
ADMINISTRATION, ORAL;
ANIMALS;
BIOLOGICAL AVAILABILITY;
CACO-2 CELLS;
HUMANS;
ILEUM;
INTESTINAL ABSORPTION;
MALE;
MANNITOL;
PHARMACEUTICAL PREPARATIONS;
RATS;
RATS, SPRAGUE-DAWLEY;
REFERENCE STANDARDS;
SPECIES SPECIFICITY;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 0031413597
PISSN: 07248741
EISSN: None
Source Type: Journal
DOI: 10.1023/A:1012148300807 Document Type: Article |
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Times cited : (26)
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References (17)
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