SAAG-4 is a novel mosquito salivary protein that programmes host CD4 + T cells to express IL-4

Parasite Immunology

Volumn 31, Issue 6, 2009, Pages 287-295

  Boppana, V D ^a,c   Thangamani, S ^a,c   Adler, A J ^b,c   Wikel, S K ^a,c  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^c UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

Author keywords

Cell activation; Cytokines; Mosquitoes; Rodent; Th1 Th2 cells

Indexed keywords

GAMMA INTERFERON; GENE PRODUCT; INTERLEUKIN 4; SALIVA PROTEIN;

ADOPTIVE TRANSFER; AEDES AEGYPTI; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CYTOKINE RELEASE; DISEASE TRANSMISSION; HOST CELL; IMMUNE SYSTEM; MALE; MOLECULAR WEIGHT; MOSQUITO; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; TH1 CELL; TH2 CELL;

ADOPTIVE TRANSFER; AEDES; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; FEMALE; INTERFERON-GAMMA; INTERLEUKIN-4; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; SALIVARY PROTEINS AND PEPTIDES;

AEDES AEGYPTI; RODENTIA;

EID: 66449088644     PISSN: 01419838     EISSN: 13653024     Source Type: Journal    
DOI: 10.1111/j.1365-3024.2009.01096.x     Document Type: Article

References (44)

1. Hill CA, Kafatos FC, Stansfield SK Collins FH. Arthropod-borne diseases: vector control in the genomics era. Nat Rev Microbiol 2005 3 : 262 268. (Pubitemid 40298225)
2. Dennis DT Piesman JF. Overview of tick-borne infections of humans. In Goodman JL, Dennis DT Sonenshine DE (eds) : Tick-borne Diseases of Humans. Washington DC, American Society for Microbiology 2005 : 3 11.
3. Gubler DJ. The global emergence/resurgence of arboviral diseases as public health problems. Arch Med Res 2002 33 : 330 342. (Pubitemid 35299553)
4. Christophers SR. Aedes Aegypti (L.) The Yellow Fever Mosquito: Its Life History, Bionomics and Structure. Cambridge, UK, Cambridge University Press, 1960 : 1 739.
5. Kyle JL Harris E. Global spread and persistence of dengue. Ann Rev Microbiol 2008 62 : 71 92.
6. Barrett ADT Higgs S. Yellow fever: a disease that has yet to be conquered. Ann Rev Entomol 2007 52 : 209 229. (Pubitemid 46133569)
7. Pialoux G, Gauzere B-A, Jaureguiberry S Strobel M. Chikungunya, an epidemic arbovirosis. Lancet Infect Dis 2007 7 : 319 327. (Pubitemid 46613868)
8. Schneider B Higgs S. The enhancement of arbovirus transmission and disease by mosquito saliva is associated with modulation of the host immune response. Trans Royal Soc Trop Med Hyg 2008 102 : 400 408.
9. Edwards JF, Higgs S Beaty BJ. Mosquito feeding-induced enhancement of Cache Valley virus (Bunyaviridae) infection in mice. J Med Entomol 1998 35 : 261 265. (Pubitemid 128462282)
10. Schneider BS, Soong L, Girard YA, Campbell G, Mason P Higgs S. Potentiation of West Nile encephalitis by mosquito feeding. Viral Immunol 2006 19 : 74 82.
11. Esmon CT. Interactions between the innate immune and blood coagulation systems. Trends Immunol 2004 25 : 536 542. (Pubitemid 39208352)
12. Stark KR James AA. Isolation and characterization of the gene encoding a novel factor Xa-directed anticoagulant from the yellow fever mosquito, Aedes aegypti. J Biol Chem 1998 273 : 20802 20809. (Pubitemid 28385358)
13. Ribeiro JM, Sarkis JJ, Rossignol PA Spielman A. Salivary apyrase of Aedes aegypti: characterization and secretory fate. Comp Biochem Physiol, Series B 1984 79 : 81 86.
14. Champagne DE, Smartt CT, Ribeiro JM James AA. The salivary gland-specific apyrase of the mosquito Aedes aegypti is a member of the 5′-nucleotidase family. Proc Natl Acad Sci USA 1995 92 : 694 698.
15. Champagne DE, Ribeiro JM. Sialokinin I and II: vasodilatory tachykinins from the yellow fever mosquito Aedes aegypti. Proc Natl Acad Sci USA 1994 91 : 138 142. (Pubitemid 24018658)
16. Ribeiro JMC Valenzuela JG. The salivary purine nucleosidase of the mosquito, Aedes aegypti. Insect Biochem Mol Biol 2003 33 : 13 22. (Pubitemid 35426640)
17. Calvo E, Mans BJ, Andersen JF Ribeiro JMC. Function and evolution of a mosquito salivary protein family. J Biol Chem 2006 281 : 1935 1942. (Pubitemid 43845779)
18. Bissonette EY, Rossignol PA Befus AD. Extracts of mosquito salivary gland inhibit tumor necrosis factor alpha. Parasite Immunol 1993 15 : 27 33.
19. Tortorella D, Gewurz BE, Furman MH, Schust DJ Ploegh HL. Viral subversion of the immune system. Ann Rev Immunol 2000 18 : 861 926. (Pubitemid 30365400)
20. Cross ML, Cupp EW Enriquez FJ. Differential modulation of murine cellular immune responses by salivary gland extracts of Aedes aegypti. Am J Trop Med Hyg 1994 51 : 690 696. (Pubitemid 24378567)
21. Zeidner NS, Higgs S, Happ CM, Beaty BJ Miller BR. Mosquito feeding modulates Th1 and Th2 cytokines in flavivirus susceptible mice: an effect mimicked by injection of sialokinins, but not demonstrated in flavivirus resistant mice. Parasite Immunol 1999 21 : 35 44. (Pubitemid 29050398)
22. Schneider BS, Soong L, Zeidner NS Higgs S. Aedes aegypti salivary gland extracts modulate anti-viral and Th1/Th2 cytokine responses to Sindbis virus infection. Viral Immunol 2004 17 : 565 573. (Pubitemid 40054236)
23. Ribeiro JMC, Arca B, Lombardo F, et al. An annotated catalogue of salivary gland transcripts in the adult female mosquito, Aedes aegypti. BMC Genomics 2007 8 : 6 doi:.
24. + T cells responding to cognate antigen to develop the capacity to express IL-4. Parasite Immunol 2007 29 : 485 499. (Pubitemid 47460177)
25. + single positive cells with a class II major histocompatibility complex-restricted receptor. J Exp Med 1994 180 : 25 34. (Pubitemid 24181052)
26. Higgins AD, Mihalyo MA, McGary PW Adler AJ. CD4 cell priming and tolerization are differentially programmed by APCs upon initial engagement. J Immunol 2002 168 : 5573 5581. (Pubitemid 34556137)
27. Doody ADH, Kovalchin JT, Mihalyo MA, Hagymasi AT, Drake CG Adler AJ. Glycoprotein 96 can chaperone both MHC class I- and class II-restricted epitopes for in vivo presentation, but selectively primes CD8+ T cell effector function. J Immunol 2004 172 : 6087 6092. (Pubitemid 38621211)
28. Higgs S. Care, maintenance, and experimental infestation of mosquitoes. In Marquardt WC, Black WC IV, Freier JE, et al. (eds) : Biology of Disease Vectors, 2nd edn. San Diego, CA, Elsevier Academic Press, 2005 733 739.
29. Smith PK, Krohn RI, Hermanson GT, et al. Measurement of protein using bicinchoninic acid. Anal Biochem 1985 150 : 76 85. (Pubitemid 16258399)
30. Klinman DM, Yamshchikov G Ishigatsubo Y. Contribution of CpG motifs to the immunogenicity of DNA vaccines. J Immunol 1997 158 : 3635 3639. (Pubitemid 127488716)
31. Martin-Orozco E, Kobayashi H, Van Uden J, Nguyen M-D, Kornbluth RS Raz E. Enhancement of antigen-presenting cell surface molecules involved in cognate interactions by immunostimulatory DNA sequences. Int Immunol 1999 11 : 1111 1118. (Pubitemid 29338753)
32. Wikel SK. Immune responses to arthropods and their products. Ann Rev Entomol 1982 27 : 21 48.
33. Ribeiro JMC. Blood-feeding arthropods: Live syringes or invertebrate pharmacologists? Infec Agents Dis 1995 4 : 143 152.
34. Schoeler GB Wikel SK. Modulation of host immunity by haematophagous arthropods. Ann Trop Med Parasitol 2001 95 : 755 771. (Pubitemid 34008366)
35. Shililu J, Ghebremeskel T, Mengistu S, et al. High seasonal variation in entomological inoculation rates in Eritrea, a semi-arid region of unstable malaria in Africa. Am J Trop Med Hyg 2003 69 : 607 613. (Pubitemid 38248231)
36. Wikel SK. Modulation of the host immune system by ectoparasitic arthropods. Bioscience 1999 49 : 311 320.
37. Peng Z Simons FE. Advances in mosquito allergy. Curr Opin Allergy Clin Immunol 2007 7 : 350 354. (Pubitemid 47052025)
38. Reese TA, Liang H-E Tager AM, et al. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 2007 447 : 92 97.
39. Dillon S, Agrawal A Van Dyke T, et al. A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells. J Immunol 2004 172 : 4733 4743. (Pubitemid 38456394)
40. Whelan M, Harnett MM, Houston KM, Patel V, Harnett W Rigley KP. A filarial nematode-secreted product signals dendritic cells to acquire a phenotype that drives development of Th2 cells. J Immunol 2000 164 : 6453 6460. (Pubitemid 30408828)
41. Agrawal S, Agrawal A & Doughty B, et al. Different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen- activated protein kinases and c-Fos. J Immunol 2003 171 : 4984 4989. (Pubitemid 37432777)
42. Denkers EY. From cells to signaling cascades: manipulation of innate immunity by Toxoplasma gondii. FEMS Immunol Med Microbiol 2003 39 : 193 203. (Pubitemid 37456834)
43. MacDonald AS, Straw AD, Bauman B Pearce EJ. CD8-dendritic cell activation status plays an integral role in influencing Th2 response development. J Immunol 2001 167 : 1982 1988. (Pubitemid 32747504)
44. Pulendran B, Kumar P, Cutler CW, Mohamadzadeh M, Van Dyke T Banchereau J. Lipopolysaccharides from distinct pathogens induce different classes of immune responses in vivo. J Immunol 2001 167 : 5067 5076. (Pubitemid 33009740)