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Volumn 286, Issue 1 30-1, 2004, Pages

BMP4 signaling induces senescence and modulates the oncogenic phenotype of A549 lung adenocarcinoma cells

Author keywords

Bone morphogenetic protein 4; Engelbreth Holm Swarm matrix invasion; Senescence associated galactosidase activity; Telomerase; Xenograft tumor

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; PROTEIN BCL 2; SMAD1 PROTEIN; TELOMERASE; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

EID: 0346096906     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00160.2003     Document Type: Article
Times cited : (68)

References (25)
  • 1
    • 0036210318 scopus 로고    scopus 로고
    • Review of current progress in the structure and function of Smad proteins
    • Chen W, Fu X, and Sheng Z. Review of current progress in the structure and function of Smad proteins. Chin Med J (Engl) 115: 446-450, 2002.
    • (2002) Chin Med J (Engl) , vol.115 , pp. 446-450
    • Chen, W.1    Fu, X.2    Sheng, Z.3
  • 2
    • 0032710534 scopus 로고    scopus 로고
    • Identification and characterization of different subpopulations in human lung adenocarcinoma cell line (A549)
    • Croce MV, Colussi AG, Price MR, and Segal-Eiras A. Identification and characterization of different subpopulations in human lung adenocarcinoma cell line (A549). Pathol Oncol Res 5: 197-204, 1999.
    • (1999) Pathol Oncol Res , vol.5 , pp. 197-204
    • Croce, M.V.1    Colussi, A.G.2    Price, M.R.3    Segal-Eiras, A.4
  • 4
    • 0034810710 scopus 로고    scopus 로고
    • BMP-7-induced cell cycle arrest of anaplastic thyroid carcinoma cells via p21 (CIP1) and p27 (KIP1)
    • Franzen A and Heldin NE. BMP-7-induced cell cycle arrest of anaplastic thyroid carcinoma cells via p21 (CIP1) and p27 (KIP1). Biochem Biophys Res Commun 285: 773-781, 2001.
    • (2001) Biochem Biophys Res Commun , vol.285 , pp. 773-781
    • Franzen, A.1    Heldin, N.E.2
  • 6
    • 0034674353 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 blocks MDA MB231 human breast cancer cell proliferation by inhibiting cyclin-dependent kinase-mediated retinoblastome protein phosphorylation
    • Ghosh-Choudbury N, Woodruff K, Qi W, Celeste A, Abboud SL, and Ghosh-Choudbury G. Bone morphogenetic protein-2 blocks MDA MB231 human breast cancer cell proliferation by inhibiting cyclin-dependent kinase-mediated retinoblastome protein phosphorylation. Biochem Biophys Res Commun 272: 705-711, 2000.
    • (2000) Biochem Biophys Res Commun , vol.272 , pp. 705-711
    • Ghosh-Choudbury, N.1    Woodruff, K.2    Qi, W.3    Celeste, A.4    Abboud, S.L.5    Ghosh-Choudbury, G.6
  • 7
    • 0035863916 scopus 로고    scopus 로고
    • Bone morphogenetic protein-4 inhibits proliferation and induces apoptosis of multiple myeloma cells
    • Hjertner O, Hjorth-Hansen H, Borset M, Seidel C, Waage A, and Sundan A. Bone morphogenetic protein-4 inhibits proliferation and induces apoptosis of multiple myeloma cells. Blood 97: 516-522, 2001.
    • (2001) Blood , vol.97 , pp. 516-522
    • Hjertner, O.1    Hjorth-Hansen, H.2    Borset, M.3    Seidel, C.4    Waage, A.5    Sundan, A.6
  • 8
    • 0034533657 scopus 로고    scopus 로고
    • Signaling of transforming growth factor-beta family members through Smad proteins
    • Itoh S, Itoh F, Gourmans MG, and Ten Dijke P. Signaling of transforming growth factor-beta family members through Smad proteins. Eur J Biochem 267: 6954-6967, 2000.
    • (2000) Eur J Biochem , vol.267 , pp. 6954-6967
    • Itoh, S.1    Itoh, F.2    Gourmans, M.G.3    Ten Dijke, P.4
  • 9
    • 0034660656 scopus 로고    scopus 로고
    • Differential expression of a novel C-terminally truncated splice form of SMAD5 in hematopoietic stem cells and leukemia
    • Jiang Y, Liang H, Guo W, Kottickal LV, and Nagarajan L. Differential expression of a novel C-terminally truncated splice form of SMAD5 in hematopoietic stem cells and leukemia. Blood 95: 3945-3950, 2000.
    • (2000) Blood , vol.95 , pp. 3945-3950
    • Jiang, Y.1    Liang, H.2    Guo, W.3    Kottickal, L.V.4    Nagarajan, L.5
  • 11
    • 0033525019 scopus 로고    scopus 로고
    • Transforming growth factor β triggers two independent-senescent programs in cancer cells
    • Katakura Y, Nakata E, Miura T, and Shirahata S. Transforming growth factor β triggers two independent-senescent programs in cancer cells. Biochem Biophys Res Commun 255: 110-115, 1999.
    • (1999) Biochem Biophys Res Commun , vol.255 , pp. 110-115
    • Katakura, Y.1    Nakata, E.2    Miura, T.3    Shirahata, S.4
  • 13
    • 0017275417 scopus 로고
    • A continuous tumor cell line from a human lung carcinoma with properties of type II alveolar epithelial cells
    • Lieber A, Smith B, Szakal A, Nelson-Rees W, and Todaro G. A continuous tumor cell line from a human lung carcinoma with properties of type II alveolar epithelial cells. Int J Cancer 17: 62-70, 1976.
    • (1976) Int J Cancer , vol.17 , pp. 62-70
    • Lieber, A.1    Smith, B.2    Szakal, A.3    Nelson-Rees, W.4    Todaro, G.5
  • 14
    • 0034644472 scopus 로고    scopus 로고
    • TGF beta signaling in growth control cancer, and heritable disorders
    • Massague J, Blain SW, and Lo RS. TGF beta signaling in growth control, cancer, and heritable disorders. Cell 103: 295-309, 2000.
    • (2000) Cell , vol.103 , pp. 295-309
    • Massague, J.1    Blain, S.W.2    Lo, R.S.3
  • 15
    • 0037085287 scopus 로고    scopus 로고
    • The role of bone morphogenic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways
    • Nohe A, Hassel S, Ehrich M, Neubauer F, Sebald W, Henis YI, and Kraus P. The role of bone morphogenic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways. J Biol Chem 277: 5330-5338, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 5330-5338
    • Nohe, A.1    Hassel, S.2    Ehrich, M.3    Neubauer, F.4    Sebald, W.5    Henis, Y.I.6    Kraus, P.7
  • 16
    • 0036148661 scopus 로고    scopus 로고
    • Role of SMAD1 and SMAD4 proteins in the induction of p21WAF1, Cip1 during bone morphogenic protein-induced growth arrest in human breast cancer cells
    • Pouliot F and Labrie C. Role of SMAD1 and SMAD4 proteins in the induction of p21WAF1, Cip1 during bone morphogenic protein-induced growth arrest in human breast cancer cells. J Endocrinol 172: 187-198, 2002.
    • (2002) J Endocrinol , vol.172 , pp. 187-198
    • Pouliot, F.1    Labrie, C.2
  • 17
    • 0030735234 scopus 로고    scopus 로고
    • Transforming growth factor beta 1 increases the expressions of high molecular weight tropomyosin isoforms and vinculin and suppresses the transformed phenotype in lung carcinoma calls
    • Tada A, Kato H, Takenaga K, and Hagesawa S. Transforming growth factor beta 1 increases the expressions of high molecular weight tropomyosin isoforms and vinculin and suppresses the transformed phenotype in lung carcinoma calls. Cancer Lett 121: 31-37, 1997.
    • (1997) Cancer Lett , vol.121 , pp. 31-37
    • Tada, A.1    Kato, H.2    Takenaga, K.3    Hagesawa, S.4
  • 18
    • 0031855504 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 suppresses the transformed phenotype and restores actin microfilaments of human lung cancer A549 cells
    • Tada A, Nishihara T, and Kato H. Bone morphogenetic protein 2 suppresses the transformed phenotype and restores actin microfilaments of human lung cancer A549 cells. Oncol Rep 5: 1137-1140, 1998.
    • (1998) Oncol Rep , vol.5 , pp. 1137-1140
    • Tada, A.1    Nishihara, T.2    Kato, H.3
  • 20
    • 0035504887 scopus 로고    scopus 로고
    • Intracellular BMP signaling in vertebrates: Pathway or network?
    • Von Bubnoff A and Cho KW. Intracellular BMP signaling in vertebrates: pathway or network? Dev Biol 239: 1-14, 2001.
    • (2001) Dev Biol , vol.239 , pp. 1-14
    • Von Bubnoff, A.1    Cho, K.W.2
  • 21
    • 0035935996 scopus 로고    scopus 로고
    • Overexpression of bone morphogenetic protein-6 (BMP-6) in murine epidermis suppresses tumor formation by induction of apoptosis and down-regulation of fos/jun family members
    • Wach S, Schirmacher P, Protschka M, and Blessing M. Overexpression of bone morphogenetic protein-6 (BMP-6) in murine epidermis suppresses tumor formation by induction of apoptosis and down-regulation of fos/jun family members. Oncogene 20: 7761-7769, 2001.
    • (2001) Oncogene , vol.20 , pp. 7761-7769
    • Wach, S.1    Schirmacher, P.2    Protschka, M.3    Blessing, M.4
  • 24
    • 0034604108 scopus 로고    scopus 로고
    • Heterogeneities in the biological and biochemical functions of Smad2 and Smad4 mutants naturally occurring in human lung cancers
    • Yanagisawa K, Uchida K, Nagatake M, Masuda A, Sugiyama M, Saito T, Yamaki K, Takahashi T, and Osada H. Heterogeneities in the biological and biochemical functions of Smad2 and Smad4 mutants naturally occurring in human lung cancers. Oncogene 19: 2305-2311, 2000.
    • (2000) Oncogene , vol.19 , pp. 2305-2311
    • Yanagisawa, K.1    Uchida, K.2    Nagatake, M.3    Masuda, A.4    Sugiyama, M.5    Saito, T.6    Yamaki, K.7    Takahashi, T.8    Osada, H.9
  • 25
    • 0026666784 scopus 로고
    • Secretion of gelatinases and tissue inhibitors of metalloproteinases by human lung cancer cell lines and revertant cell lines: Not an invariant correlation with metastasis
    • Zucker S, Lysik RM, Malik M, Bauer BA, Caamano J, and Klein-Szanto AJ. Secretion of gelatinases and tissue inhibitors of metalloproteinases by human lung cancer cell lines and revertant cell lines: not an invariant correlation with metastasis. Int J Cancer 52: 366-371, 1992.
    • (1992) Int J Cancer , vol.52 , pp. 366-371
    • Zucker, S.1    Lysik, R.M.2    Malik, M.3    Bauer, B.A.4    Caamano, J.5    Klein-Szanto, A.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.