메뉴 건너뛰기




Volumn 5, Issue 4, 2009, Pages

Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; ATR PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CIRCULAR DNA; DOUBLE STRANDED DNA; GLYCOPROTEIN E1; GLYCOPROTEIN E2; HISTONE H2AX; KU ANTIGEN; MRE11 PROTEIN; NIBRIN; ONCOPROTEIN; RAD50 PROTEIN; VIRUS PROTEIN; DNA BINDING PROTEIN; E1 PROTEIN, HUMAN PAPILLOMAVIRUS 16; E2 PROTEIN, HUMAN PAPILLOMAVIRUS TYPE 16; ONCOGENE PROTEIN E1, HUMAN PAPILLOMAVIRUS TYPE 18; ONCOGENE PROTEIN E2, HUMAN PAPILLOMAVIRUS TYPE 18;

EID: 66349112294     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000397     Document Type: Article
Times cited : (157)

References (80)
  • 1
    • 66349101207 scopus 로고    scopus 로고
    • Howley PM, Lowy DR (2001) Papillomaviruses and Their Replication. Knipe DM aH, PM, eds. Philadelphia: Lippincott Williams & Wilkins. Pp 2197-2230.
    • Howley PM, Lowy DR (2001) Papillomaviruses and Their Replication. Knipe DM aH, PM, eds. Philadelphia: Lippincott Williams & Wilkins. Pp 2197-2230.
  • 2
    • 0026034125 scopus 로고
    • Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames
    • Ustav M, Stenlund A (1991) Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames. Embo J 10: 449-457.
    • (1991) Embo J , vol.10 , pp. 449-457
    • Ustav, M.1    Stenlund, A.2
  • 3
    • 0026769936 scopus 로고
    • Viral E1 and E2 proteins support replication of homologous and heterologous papillomaviral origins
    • Chiang CM, Ustav M, Stenlund A, Ho TF, Broker TR, et al. (1992) Viral E1 and E2 proteins support replication of homologous and heterologous papillomaviral origins. Proc Natl Acad Sci U S A 89: 5799-5803.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 5799-5803
    • Chiang, C.M.1    Ustav, M.2    Stenlund, A.3    Ho, T.F.4    Broker, T.R.5
  • 4
    • 0027976786 scopus 로고
    • Replication of human papillomavirus (HPV) DNAs supported by the HPV type 18 E1 and E2 proteins
    • Sverdrup F, Khan SA (1994) Replication of human papillomavirus (HPV) DNAs supported by the HPV type 18 E1 and E2 proteins. J Virol 68: 505-509.
    • (1994) J Virol , vol.68 , pp. 505-509
    • Sverdrup, F.1    Khan, S.A.2
  • 5
    • 59349090094 scopus 로고    scopus 로고
    • Papillomavirus DNA replication - mfrom initiation to genomic instability
    • Kadaja M, Silla T, Ustav E, Ustav M (2009) Papillomavirus DNA replication - mfrom initiation to genomic instability. Virology 384: 360-368.
    • (2009) Virology , vol.384 , pp. 360-368
    • Kadaja, M.1    Silla, T.2    Ustav, E.3    Ustav, M.4
  • 6
    • 0027288327 scopus 로고
    • The E1 protein of bovine papilloma virus 1 is an ATP-dependent DNA helicase
    • Yang L, Mohr I, Fouts E, Lim DA, Nohaile M, et al. (1993) The E1 protein of bovine papilloma virus 1 is an ATP-dependent DNA helicase. Proc Natl Acad Sci U S A 90: 5086-5090.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 5086-5090
    • Yang, L.1    Mohr, I.2    Fouts, E.3    Lim, D.A.4    Nohaile, M.5
  • 7
    • 0031926580 scopus 로고    scopus 로고
    • The papillomavirus E1 protein forms a DNAdependent hexameric complex with ATPase and DNA helicase activities
    • Sedman J, Stenlund A (1998) The papillomavirus E1 protein forms a DNAdependent hexameric complex with ATPase and DNA helicase activities. J Virol 72: 6893-6897.
    • (1998) J Virol , vol.72 , pp. 6893-6897
    • Sedman, J.1    Stenlund, A.2
  • 8
    • 0026060519 scopus 로고
    • Identification of the origin of replication of bovine papillomavirus and characterization of the viral origin recognition factor E1
    • Ustav M, Ustav E, Szymanski P, Stenlund A (1991) Identification of the origin of replication of bovine papillomavirus and characterization of the viral origin recognition factor E1. Embo J 10: 4321-4329.
    • (1991) Embo J , vol.10 , pp. 4321-4329
    • Ustav, M.1    Ustav, E.2    Szymanski, P.3    Stenlund, A.4
  • 9
    • 0027398356 scopus 로고
    • The bovine papillomavirus origin of replication requires a binding site for the E2 transcriptional activator
    • Ustav E, Ustav M, Szymanski P, Stenlund A (1993) The bovine papillomavirus origin of replication requires a binding site for the E2 transcriptional activator. Proc Natl Acad Sci U S A 90: 898-902.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 898-902
    • Ustav, E.1    Ustav, M.2    Szymanski, P.3    Stenlund, A.4
  • 10
    • 0026471039 scopus 로고
    • The E2 binding sites determine the efficiency of replication for the origin of human papillomavirus type 18
    • Remm M, Brain R, Jenkins JR (1992) The E2 binding sites determine the efficiency of replication for the origin of human papillomavirus type 18. Nucleic Acids Res 20: 6015-6021.
    • (1992) Nucleic Acids Res , vol.20 , pp. 6015-6021
    • Remm, M.1    Brain, R.2    Jenkins, J.R.3
  • 11
    • 0028977962 scopus 로고
    • cis-Acting components of human papillomavirus (HPV) DNA replication: Linker substitution analysis of the HPV type 11 origin
    • Russell J, Botchan MR (1995) cis-Acting components of human papillomavirus (HPV) DNA replication: linker substitution analysis of the HPV type 11 origin. J Virol 69: 651-660.
    • (1995) J Virol , vol.69 , pp. 651-660
    • Russell, J.1    Botchan, M.R.2
  • 12
    • 0141891451 scopus 로고    scopus 로고
    • Initiation of DNA replication: Lessons from viral initiator proteins
    • Stenlund A (2003) Initiation of DNA replication: lessons from viral initiator proteins. Nat Rev Mol Cell Biol 4: 777-785.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 777-785
    • Stenlund, A.1
  • 13
    • 0026495813 scopus 로고
    • Random-choice replication of extrachromosomal bovine papillomavirus (BPV) molecules in heterogeneous, clonally derived BPV-infected cell lines
    • Ravnan JB, Gilbert DM, Ten Hagen KG, Cohen SN (1992) Random-choice replication of extrachromosomal bovine papillomavirus (BPV) molecules in heterogeneous, clonally derived BPV-infected cell lines. J Virol 66: 6946-6952.
    • (1992) J Virol , vol.66 , pp. 6946-6952
    • Ravnan, J.B.1    Gilbert, D.M.2    Ten Hagen, K.G.3    Cohen, S.N.4
  • 14
    • 0030048803 scopus 로고    scopus 로고
    • Cis and trans requirements for stable episomal maintenance of the BPV-1 replicator
    • Piirsoo M, Ustav E, Mandel T, Stenlund A, Ustav M (1996) Cis and trans requirements for stable episomal maintenance of the BPV-1 replicator. Embo J 15: 1-11.
    • (1996) Embo J , vol.15 , pp. 1-11
    • Piirsoo, M.1    Ustav, E.2    Mandel, T.3    Stenlund, A.4    Ustav, M.5
  • 15
    • 0026335741 scopus 로고
    • Episomal and integrated human papillomavirus in cervical neoplasia shown by nonisotopic in situ hybridisation
    • Cooper K, Herrington CS, Stickland JE, Evans MF, McGee JO (1991) Episomal and integrated human papillomavirus in cervical neoplasia shown by nonisotopic in situ hybridisation. J Clin Pathol 44: 990-996.
    • (1991) J Clin Pathol , vol.44 , pp. 990-996
    • Cooper, K.1    Herrington, C.S.2    Stickland, J.E.3    Evans, M.F.4    McGee, J.O.5
  • 16
    • 0028262230 scopus 로고
    • Coexistence of episomal and integrated HPV16 DNA in squamous cell carcinoma of the cervix
    • Kristiansen E, Jenkins A, Holm R (1994) Coexistence of episomal and integrated HPV16 DNA in squamous cell carcinoma of the cervix. J Clin Pathol 47: 253-256.
    • (1994) J Clin Pathol , vol.47 , pp. 253-256
    • Kristiansen, E.1    Jenkins, A.2    Holm, R.3
  • 17
    • 0036895804 scopus 로고    scopus 로고
    • Changes in cervical keratinocyte gene expression associated with integration of huma papillomavirus 16
    • Alazawi W, Pett M, Arch B, Scott L, Freeman T, et al. (2002) Changes in cervical keratinocyte gene expression associated with integration of huma papillomavirus 16. Cancer Res 62: 6959-6965.
    • (2002) Cancer Res , vol.62 , pp. 6959-6965
    • Alazawi, W.1    Pett, M.2    Arch, B.3    Scott, L.4    Freeman, T.5
  • 18
    • 0036313215 scopus 로고    scopus 로고
    • Single copy heterozygote integration of HPV 33 in chromosomal band 5p14 is found in an epithelial cell clone with selective growth advantage
    • Peitsaro P, Hietanen S, Johansson B, Lakkala T, Syrjanen S (2002) Single copy heterozygote integration of HPV 33 in chromosomal band 5p14 is found in an epithelial cell clone with selective growth advantage. Carcinogenesis 23: 1057-1064.
    • (2002) Carcinogenesis , vol.23 , pp. 1057-1064
    • Peitsaro, P.1    Hietanen, S.2    Johansson, B.3    Lakkala, T.4    Syrjanen, S.5
  • 19
    • 0036196505 scopus 로고    scopus 로고
    • Integrated human papillomavirus type 16 is frequently found in cervical cancer precursors as demonstrated by a novel quantitative real-time PCR technique
    • Peitsaro P, Johansson B, Syrjanen S (2002) Integrated human papillomavirus type 16 is frequently found in cervical cancer precursors as demonstrated by a novel quantitative real-time PCR technique. J Clin Microbiol 40: 886-891.
    • (2002) J Clin Microbiol , vol.40 , pp. 886-891
    • Peitsaro, P.1    Johansson, B.2    Syrjanen, S.3
  • 20
    • 22044437091 scopus 로고    scopus 로고
    • Type distribution, viral load and integration status of high-risk human papillomaviruses in pre-stages of cervical cancer (CIN)
    • Andersson S, Safari H, Mints M, Lewensohn-Fuchs I, Gyllensten U, et al. (2005) Type distribution, viral load and integration status of high-risk human papillomaviruses in pre-stages of cervical cancer (CIN). Br J Cancer 92: 2195-2200.
    • (2005) Br J Cancer , vol.92 , pp. 2195-2200
    • Andersson, S.1    Safari, H.2    Mints, M.3    Lewensohn-Fuchs, I.4    Gyllensten, U.5
  • 21
    • 33646596267 scopus 로고    scopus 로고
    • Human papillomavirus type 16 integration in cervical carcinoma in situ and in invasive cervical cancer
    • Arias-Pulido H, Peyton CL, Joste NE, Vargas H, Wheeler CM (2006) Human papillomavirus type 16 integration in cervical carcinoma in situ and in invasive cervical cancer. J Clin Microbiol 44: 1755-1762.
    • (2006) J Clin Microbiol , vol.44 , pp. 1755-1762
    • Arias-Pulido, H.1    Peyton, C.L.2    Joste, N.E.3    Vargas, H.4    Wheeler, C.M.5
  • 22
    • 33646426100 scopus 로고    scopus 로고
    • Early integration of high copy HPV16 detectable in women with normal and low grade cervical cytology and histology
    • Kulmala SM, Syrjanen SM, Gyllensten UB, Shabalova IP, Petrovichev N, et al. (2006) Early integration of high copy HPV16 detectable in women with normal and low grade cervical cytology and histology. J Clin Pathol 59: 513-517.
    • (2006) J Clin Pathol , vol.59 , pp. 513-517
    • Kulmala, S.M.1    Syrjanen, S.M.2    Gyllensten, U.B.3    Shabalova, I.P.4    Petrovichev, N.5
  • 23
    • 33644870575 scopus 로고    scopus 로고
    • Selection of cervical keratinocytes containing integrated HPV16 associates with episome loss and an endogenous antiviral response
    • Pett MR, Herdman MT, Palmer RD, Yeo GS, Shivji MK, et al. (2006) Selection of cervical keratinocytes containing integrated HPV16 associates with episome loss and an endogenous antiviral response. Proc Natl Acad Sci U S A 103: 3822-3827.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 3822-3827
    • Pett, M.R.1    Herdman, M.T.2    Palmer, R.D.3    Yeo, G.S.4    Shivji, M.K.5
  • 24
    • 34547099574 scopus 로고    scopus 로고
    • Integration of high-risk human papillomavirus: A key event in cervical carcinogenesis?
    • Pett M, Coleman N (2007) Integration of high-risk human papillomavirus: a key event in cervical carcinogenesis? J Pathol 212: 356-367.
    • (2007) J Pathol , vol.212 , pp. 356-367
    • Pett, M.1    Coleman, N.2
  • 25
    • 54249105939 scopus 로고    scopus 로고
    • Characterization of naturally occurring HPV16 integration sites isolated from cervical keratinocytes under noncompetitive conditions
    • Dall KL, Scarpini CG, Roberts I, Winder DM, Stanley MA, et al. (2008) Characterization of naturally occurring HPV16 integration sites isolated from cervical keratinocytes under noncompetitive conditions. Cancer Res 68: 8249-8259.
    • (2008) Cancer Res , vol.68 , pp. 8249-8259
    • Dall, K.L.1    Scarpini, C.G.2    Roberts, I.3    Winder, D.M.4    Stanley, M.A.5
  • 26
    • 1242316161 scopus 로고    scopus 로고
    • Acquisition of high-level chromosomal instability is associated with integration of human papillomavirus type 16 in cervical keratinocytes
    • Pett MR, Alazawi WO, Roberts I, Dowen S, Smith DI, et al. (2004) Acquisition of high-level chromosomal instability is associated with integration of human papillomavirus type 16 in cervical keratinocytes. Cancer Res 64: 1359-1368.
    • (2004) Cancer Res , vol.64 , pp. 1359-1368
    • Pett, M.R.1    Alazawi, W.O.2    Roberts, I.3    Dowen, S.4    Smith, D.I.5
  • 27
    • 0028937867 scopus 로고
    • Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells
    • Jeon S, Allen-Hoffmann BL, Lambert PF (1995) Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells. J Virol 69: 2989-2997.
    • (1995) J Virol , vol.69 , pp. 2989-2997
    • Jeon, S.1    Allen-Hoffmann, B.L.2    Lambert, P.F.3
  • 28
    • 0026548255 scopus 로고
    • Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity
    • Romanczuk H, Howley PM (1992) Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity. Proc Natl Acad Sci U S A 89: 3159-3163.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 3159-3163
    • Romanczuk, H.1    Howley, P.M.2
  • 29
    • 0025311444 scopus 로고
    • Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters
    • Romanczuk H, Thierry F, Howley PM (1990) Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters. J Virol 64: 2849-2859.
    • (1990) J Virol , vol.64 , pp. 2849-2859
    • Romanczuk, H.1    Thierry, F.2    Howley, P.M.3
  • 30
    • 34247198246 scopus 로고    scopus 로고
    • Genomic instability of the host cell induced by the human papillomavirus replication machinery
    • Kadaja M, Sumerina A, Verst T, Ojarand M, Ustav E, et al. (2007) Genomic instability of the host cell induced by the human papillomavirus replication machinery. Embo J 26: 2180-2191.
    • (2007) Embo J , vol.26 , pp. 2180-2191
    • Kadaja, M.1    Sumerina, A.2    Verst, T.3    Ojarand, M.4    Ustav, E.5
  • 32
    • 0035123112 scopus 로고    scopus 로고
    • Physical state of HPV16 and chromosomal mapping of the integrated form in cervical carcinomas
    • Kalantari M, Blennow E, Hagmar B, Johansson B (2001) Physical state of HPV16 and chromosomal mapping of the integrated form in cervical carcinomas. Diagn Mol Pathol 10: 46-54.
    • (2001) Diagn Mol Pathol , vol.10 , pp. 46-54
    • Kalantari, M.1    Blennow, E.2    Hagmar, B.3    Johansson, B.4
  • 33
    • 33749187258 scopus 로고    scopus 로고
    • MYC activation associated with the integration of HPV DNA at the MYC locus in genital tumors
    • Peter M, Rosty C, Couturier J, Radvanyi F, Teshima H, et al. (2006) MYC activation associated with the integration of HPV DNA at the MYC locus in genital tumors. Oncogene 25: 5985-5993.
    • (2006) Oncogene , vol.25 , pp. 5985-5993
    • Peter, M.1    Rosty, C.2    Couturier, J.3    Radvanyi, F.4    Teshima, H.5
  • 34
    • 1242319406 scopus 로고    scopus 로고
    • Mechanisms of genomic instability in human cancer: Insights from studies with human papillomavirus oncoproteins
    • Duensing S, Munger K (2004) Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins. Int J Cancer 109: 157-162.
    • (2004) Int J Cancer , vol.109 , pp. 157-162
    • Duensing, S.1    Munger, K.2
  • 35
    • 0036897282 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability
    • Duensing S, Munger K (2002) The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability. Cancer Res 62: 7075-7082.
    • (2002) Cancer Res , vol.62 , pp. 7075-7082
    • Duensing, S.1    Munger, K.2
  • 36
    • 0242300161 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E7 oncoprotein can induce abnormal centrosome duplication through a mechanism independent of inactivation of retinoblastoma protein family members
    • Duensing S, Munger K (2003) Human papillomavirus type 16 E7 oncoprotein can induce abnormal centrosome duplication through a mechanism independent of inactivation of retinoblastoma protein family members. J Virol 77: 12331-12335.
    • (2003) J Virol , vol.77 , pp. 12331-12335
    • Duensing, S.1    Munger, K.2
  • 37
    • 0037302447 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E2 protein has no effect on transcription from episomal viral DNA
    • Bechtold V, Beard P, Raj K (2003) Human papillomavirus type 16 E2 protein has no effect on transcription from episomal viral DNA. J Virol 77: 2021-2028.
    • (2003) J Virol , vol.77 , pp. 2021-2028
    • Bechtold, V.1    Beard, P.2    Raj, K.3
  • 38
    • 0014202537 scopus 로고
    • Selective extraction of polyoma DNA from infected mouse cell cultures
    • Hirt B (1967) Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol 26: 365-369.
    • (1967) J Mol Biol , vol.26 , pp. 365-369
    • Hirt, B.1
  • 39
    • 0038817792 scopus 로고    scopus 로고
    • Extrachromosomal circular DNA of tandemly repeated genomic sequences in Drosophila
    • Cohen S, Yacobi K, Segal D (2003) Extrachromosomal circular DNA of tandemly repeated genomic sequences in Drosophila. Genome Res 13: 1133-1145.
    • (2003) Genome Res , vol.13 , pp. 1133-1145
    • Cohen, S.1    Yacobi, K.2    Segal, D.3
  • 40
    • 0032863689 scopus 로고    scopus 로고
    • Physical and genetic mapping of mammalian replication origins
    • Dijkwel PA, Hamlin JL (1999) Physical and genetic mapping of mammalian replication origins. Methods 18: 418-431.
    • (1999) Methods , vol.18 , pp. 418-431
    • Dijkwel, P.A.1    Hamlin, J.L.2
  • 41
    • 0036093959 scopus 로고    scopus 로고
    • Induction of the bovine papillomavirus origin "onion skin"-type DNA replication at high E1 protein concentrations in vivo
    • Mannik A, Runkorg K, Jaanson N, Ustav M, Ustav E (2002) Induction of the bovine papillomavirus origin "onion skin"-type DNA replication at high E1 protein concentrations in vivo. J Virol 76: 5835-5845.
    • (2002) J Virol , vol.76 , pp. 5835-5845
    • Mannik, A.1    Runkorg, K.2    Jaanson, N.3    Ustav, M.4    Ustav, E.5
  • 42
    • 33947099546 scopus 로고    scopus 로고
    • Replication foci dynamics: Replication patterns are modulated by S-phase checkpoint kinases in fission yeast
    • Meister P, Taddei A, Ponti A, Baldacci G, Gasser SM (2007) Replication foci dynamics: replication patterns are modulated by S-phase checkpoint kinases in fission yeast. Embo J 26: 1315-1326.
    • (2007) Embo J , vol.26 , pp. 1315-1326
    • Meister, P.1    Taddei, A.2    Ponti, A.3    Baldacci, G.4    Gasser, S.M.5
  • 45
    • 0000557716 scopus 로고    scopus 로고
    • Human papillomavirus DNA replication compartments in a transient DNA replication system
    • Swindle CS, Zou N, Van Tine BA, Shaw GM, Engler JA, et al. (1999) Human papillomavirus DNA replication compartments in a transient DNA replication system. J Virol 73: 1001-1009.
    • (1999) J Virol , vol.73 , pp. 1001-1009
    • Swindle, C.S.1    Zou, N.2    Van Tine, B.A.3    Shaw, G.M.4    Engler, J.A.5
  • 46
    • 0023231597 scopus 로고
    • Molecular analysis of integrated human papillomavirus 16 sequences in the cervical cancer cell line SiHa
    • el Awady MK, Kaplan JB, O'Brien SJ, Burk RD (1987) Molecular analysis of integrated human papillomavirus 16 sequences in the cervical cancer cell line SiHa. Virology 159: 389-398.
    • (1987) Virology , vol.159 , pp. 389-398
    • el Awady, M.K.1    Kaplan, J.B.2    O'Brien, S.J.3    Burk, R.D.4
  • 47
    • 0032987565 scopus 로고    scopus 로고
    • Nucleotide sequences and further characterization of human papillomavirus DNA present in the CaSki, SiHa and HeLa cervical carcinoma cell lines
    • Meissner JD (1999) Nucleotide sequences and further characterization of human papillomavirus DNA present in the CaSki, SiHa and HeLa cervical carcinoma cell lines. J Gen Virol 80(Pt 7): 1725-1733.
    • (1999) J Gen Virol , vol.80 , Issue.PART 7 , pp. 1725-1733
    • Meissner, J.D.1
  • 48
    • 0034107327 scopus 로고    scopus 로고
    • Simultaneous molecular karyotyping and mapping of viral DNA integration sites by 25-color COBRA-FISH
    • Szuhai K, Bezrookove V, Wiegant J, Vrolijk J, Dirks RW, et al. (2000) Simultaneous molecular karyotyping and mapping of viral DNA integration sites by 25-color COBRA-FISH. Genes Chromosomes Cancer 28: 92-97.
    • (2000) Genes Chromosomes Cancer , vol.28 , pp. 92-97
    • Szuhai, K.1    Bezrookove, V.2    Wiegant, J.3    Vrolijk, J.4    Dirks, R.W.5
  • 49
    • 0344076342 scopus 로고    scopus 로고
    • Comprehensive and definitive molecular cytogenetic characterization of HeLa cells by spectral karyotyping
    • Macville M, Schrock E, Padilla-Nash H, Keck C, Ghadimi BM, et al. (1999) Comprehensive and definitive molecular cytogenetic characterization of HeLa cells by spectral karyotyping. Cancer Res 59: 141-150.
    • (1999) Cancer Res , vol.59 , pp. 141-150
    • Macville, M.1    Schrock, E.2    Padilla-Nash, H.3    Keck, C.4    Ghadimi, B.M.5
  • 50
    • 36448975490 scopus 로고    scopus 로고
    • Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies
    • Bernardi R, Pandolfi PP (2007) Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies. Nat Rev Mol Cell Biol 8: 1006-1016.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 1006-1016
    • Bernardi, R.1    Pandolfi, P.P.2
  • 51
    • 37749036302 scopus 로고    scopus 로고
    • Daxx mediates SUMOdependent transcriptional control and subnuclear compartmentalization
    • Shih HM, Chang CC, Kuo HY, Lin DY (2007) Daxx mediates SUMOdependent transcriptional control and subnuclear compartmentalization. Biochem Soc Trans 35: 1397-1400.
    • (2007) Biochem Soc Trans , vol.35 , pp. 1397-1400
    • Shih, H.M.1    Chang, C.C.2    Kuo, H.Y.3    Lin, D.Y.4
  • 52
    • 38049125555 scopus 로고    scopus 로고
    • The endless tale of non-homologous end-joining
    • Weterings E, Chen DJ (2008) The endless tale of non-homologous end-joining. Cell Res 18: 114-124.
    • (2008) Cell Res , vol.18 , pp. 114-124
    • Weterings, E.1    Chen, D.J.2
  • 53
    • 38049155945 scopus 로고    scopus 로고
    • Regulation of DNA doublestrand break repair pathway choice
    • Shrivastav M, De Haro LP, Nickoloff JA (2008) Regulation of DNA doublestrand break repair pathway choice. Cell Res 18: 134-147.
    • (2008) Cell Res , vol.18 , pp. 134-147
    • Shrivastav, M.1    De Haro, L.P.2    Nickoloff, J.A.3
  • 54
    • 33747889217 scopus 로고    scopus 로고
    • Differential usage of non-homologous end-joining and homologous recombination in double strand break repair
    • Sonoda E, Hochegger H, Saberi A, Taniguchi Y, Takeda S (2006) Differential usage of non-homologous end-joining and homologous recombination in double strand break repair. DNA Repair (Amst) 5: 1021-1029.
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1021-1029
    • Sonoda, E.1    Hochegger, H.2    Saberi, A.3    Taniguchi, Y.4    Takeda, S.5
  • 55
    • 0034641724 scopus 로고    scopus 로고
    • Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro
    • Matsuoka S, Rotman G, Ogawa A, Shiloh Y, Tamai K, et al. (2000) Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro. Proc Natl Acad Sci U S A 97: 10389-10394.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 10389-10394
    • Matsuoka, S.1    Rotman, G.2    Ogawa, A.3    Shiloh, Y.4    Tamai, K.5
  • 56
    • 0036258583 scopus 로고    scopus 로고
    • Chk2 activation and phosphorylationdependent oligomerization
    • Xu X, Tsvetkov LM, Stern DF (2002) Chk2 activation and phosphorylationdependent oligomerization. Mol Cell Biol 22: 4419-4432.
    • (2002) Mol Cell Biol , vol.22 , pp. 4419-4432
    • Xu, X.1    Tsvetkov, L.M.2    Stern, D.F.3
  • 57
    • 33750340969 scopus 로고    scopus 로고
    • DNA damage-induced cell cycle regulation and function of novel Chk2 phosphoresidues
    • Buscemi G, Carlessi L, Zannini L, Lisanti S, Fontanella E, et al. (2006) DNA damage-induced cell cycle regulation and function of novel Chk2 phosphoresidues. Mol Cell Biol 26: 7832-7845.
    • (2006) Mol Cell Biol , vol.26 , pp. 7832-7845
    • Buscemi, G.1    Carlessi, L.2    Zannini, L.3    Lisanti, S.4    Fontanella, E.5
  • 58
    • 0025739333 scopus 로고
    • Integration of papillomavirus DNA near myc genes in genital carcinomas and its consequences for proto-oncogene expression
    • Couturier J, Sastre-Garau X, Schneider-Maunoury S, Labib A, Orth G (1991) Integration of papillomavirus DNA near myc genes in genital carcinomas and its consequences for proto-oncogene expression. J Virol 65: 4534-4538.
    • (1991) J Virol , vol.65 , pp. 4534-4538
    • Couturier, J.1    Sastre-Garau, X.2    Schneider-Maunoury, S.3    Labib, A.4    Orth, G.5
  • 59
    • 0037089495 scopus 로고    scopus 로고
    • Simultaneous mapping of human papillomavirus integration sites and molecular karyotyping in short-term cultures of cervical carcinomas by using 49-color combined binary ratio labeling fluorescence in situ hybridization
    • Brink AA, Wiegant JC, Szuhai K, Tanke HJ, Kenter GG, et al. (2002) Simultaneous mapping of human papillomavirus integration sites and molecular karyotyping in short-term cultures of cervical carcinomas by using 49-color combined binary ratio labeling fluorescence in situ hybridization. Cancer Genet Cytogenet 134: 145-150.
    • (2002) Cancer Genet Cytogenet , vol.134 , pp. 145-150
    • Brink, A.A.1    Wiegant, J.C.2    Szuhai, K.3    Tanke, H.J.4    Kenter, G.G.5
  • 60
    • 0029863784 scopus 로고    scopus 로고
    • In vitro synthesis of oncogenic human papillomaviruses requires episomal genomes for differentiation-dependent late expression
    • Frattini MG, Lim HB, Laimins LA (1996) In vitro synthesis of oncogenic human papillomaviruses requires episomal genomes for differentiation-dependent late expression. Proc Natl Acad Sci U S A 93: 3062-3067.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 3062-3067
    • Frattini, M.G.1    Lim, H.B.2    Laimins, L.A.3
  • 61
    • 15244344245 scopus 로고    scopus 로고
    • The minor capsid protein L2 contributes to two steps in the human papillomavirus type 31 life cycle
    • Holmgren SC, Patterson NA, Ozbun MA, Lambert PF (2005) The minor capsid protein L2 contributes to two steps in the human papillomavirus type 31 life cycle. J Virol 79: 3938-3948.
    • (2005) J Virol , vol.79 , pp. 3938-3948
    • Holmgren, S.C.1    Patterson, N.A.2    Ozbun, M.A.3    Lambert, P.F.4
  • 62
    • 20344396122 scopus 로고    scopus 로고
    • Preventing re-replication of chromosomal DNA
    • Blow JJ, Dutta A (2005) Preventing re-replication of chromosomal DNA. Nat Rev Mol Cell Biol 6: 476-486.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 476-486
    • Blow, J.J.1    Dutta, A.2
  • 63
    • 26244431903 scopus 로고    scopus 로고
    • Right place, right time, and only once: Replication initiation in metazoans
    • Machida YJ, Hamlin JL, Dutta A (2005) Right place, right time, and only once: replication initiation in metazoans. Cell 123: 13-24.
    • (2005) Cell , vol.123 , pp. 13-24
    • Machida, Y.J.1    Hamlin, J.L.2    Dutta, A.3
  • 64
    • 0018356259 scopus 로고
    • Studies on simian virus 40 excision from cellular chromosomes
    • Botchan M, Topp W, Sambrook J (1979) Studies on simian virus 40 excision from cellular chromosomes. Cold Spring Harb Symp Quant Biol 43 Pt 2: 709-719.
    • (1979) Cold Spring Harb Symp Quant Biol , vol.43 , Issue.PART 2 , pp. 709-719
    • Botchan, M.1    Topp, W.2    Sambrook, J.3
  • 65
    • 0018933483 scopus 로고
    • Characteristics of an SV40-plasmid recombinant and its movement into and out of the genome of a murine cell
    • Hanahan D, Lane D, Lipsich L, Wigler M, Botchan M (1980) Characteristics of an SV40-plasmid recombinant and its movement into and out of the genome of a murine cell. Cell 21: 127-139.
    • (1980) Cell , vol.21 , pp. 127-139
    • Hanahan, D.1    Lane, D.2    Lipsich, L.3    Wigler, M.4    Botchan, M.5
  • 66
    • 0021632246 scopus 로고
    • DNA sequence studies of simian virus 40 chromosomal excision and integration in rat cells
    • Bullock P, Forrester W, Botchan M (1984) DNA sequence studies of simian virus 40 chromosomal excision and integration in rat cells. J Mol Biol 174: 55-84.
    • (1984) J Mol Biol , vol.174 , pp. 55-84
    • Bullock, P.1    Forrester, W.2    Botchan, M.3
  • 67
    • 0034612308 scopus 로고    scopus 로고
    • The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations
    • Ferguson DO, Sekiguchi JM, Chang S, Frank KM, Gao Y, et al. (2000) The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations. Proc Natl Acad Sci U S A 97: 6630-6633.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 6630-6633
    • Ferguson, D.O.1    Sekiguchi, J.M.2    Chang, S.3    Frank, K.M.4    Gao, Y.5
  • 68
    • 0033576687 scopus 로고    scopus 로고
    • The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts
    • Karanjawala ZE, Grawunder U, Hsieh CL, Lieber MR (1999) The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts. Curr Biol 9: 1501-1504.
    • (1999) Curr Biol , vol.9 , pp. 1501-1504
    • Karanjawala, Z.E.1    Grawunder, U.2    Hsieh, C.L.3    Lieber, M.R.4
  • 69
    • 18244379848 scopus 로고    scopus 로고
    • Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions
    • Sharpless NE, Ferguson DO, O'Hagan RC, Castrillon DH, Lee C, et al. (2001) Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions. Mol Cell 8: 1187-1196.
    • (2001) Mol Cell , vol.8 , pp. 1187-1196
    • Sharpless, N.E.1    Ferguson, D.O.2    O'Hagan, R.C.3    Castrillon, D.H.4    Lee, C.5
  • 70
    • 33747873409 scopus 로고    scopus 로고
    • Chromatin structural elements and chromosomal translocations in leukemia
    • Zhang Y, Rowley JD (2006) Chromatin structural elements and chromosomal translocations in leukemia. DNA Repair (Amst) 5: 1282-1297.
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1282-1297
    • Zhang, Y.1    Rowley, J.D.2
  • 71
    • 0037623356 scopus 로고    scopus 로고
    • A p53-dependent checkpoint pathway prevents rereplication
    • Vaziri C, Saxena S, Jeon Y, Lee C, Murata K, et al. (2003) A p53-dependent checkpoint pathway prevents rereplication. Mol Cell 11: 997-1008.
    • (2003) Mol Cell , vol.11 , pp. 997-1008
    • Vaziri, C.1    Saxena, S.2    Jeon, Y.3    Lee, C.4    Murata, K.5
  • 72
    • 0036182133 scopus 로고    scopus 로고
    • Control of DNA replication and chromosome ploidy by geminin and cyclin A
    • Mihaylov IS, Kondo T, Jones L, Ryzhikov S, Tanaka J, et al. (2002) Control of DNA replication and chromosome ploidy by geminin and cyclin A. Mol Cell Biol 22: 1868-1880.
    • (2002) Mol Cell Biol , vol.22 , pp. 1868-1880
    • Mihaylov, I.S.1    Kondo, T.2    Jones, L.3    Ryzhikov, S.4    Tanaka, J.5
  • 73
    • 3543041247 scopus 로고    scopus 로고
    • Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint
    • Zhu W, Chen Y, Dutta A (2004) Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint. Mol Cell Biol 24: 7140-7150.
    • (2004) Mol Cell Biol , vol.24 , pp. 7140-7150
    • Zhu, W.1    Chen, Y.2    Dutta, A.3
  • 74
    • 36348931639 scopus 로고    scopus 로고
    • The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted
    • Liu E, Lee AY, Chiba T, Olson E, Sun P, et al. (2007) The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted. J Cell Biol 179: 643-657.
    • (2007) J Cell Biol , vol.179 , pp. 643-657
    • Liu, E.1    Lee, A.Y.2    Chiba, T.3    Olson, E.4    Sun, P.5
  • 75
    • 33646779221 scopus 로고    scopus 로고
    • A phosphorylation map of the bovine papillomavirus E1 helicase
    • Lentz MR, Stevens SM Jr, Raynes J, Elkhoury N (2006) A phosphorylation map of the bovine papillomavirus E1 helicase. Virol J 3: 13.
    • (2006) Virol , vol.J 3 , pp. 13
    • Lentz, M.R.1    Stevens Jr, S.M.2    Raynes, J.3    Elkhoury, N.4
  • 76
    • 0142091750 scopus 로고    scopus 로고
    • Two separate replication modes of the bovine papillomavirus BPV1 origin of replication that have different sensitivity to p53
    • Ilves I, Kadaja M, Ustav M (2003) Two separate replication modes of the bovine papillomavirus BPV1 origin of replication that have different sensitivity to p53. Virus Res 96: 75-84.
    • (2003) Virus Res , vol.96 , pp. 75-84
    • Ilves, I.1    Kadaja, M.2    Ustav, M.3
  • 77
    • 4644292460 scopus 로고    scopus 로고
    • Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: Synergistic effect with mutant p53 on tumor growth and chromosomal instability-evidence of E2F-1 transcriptional control over hCdt1
    • Karakaidos P, Taraviras S, Vassiliou LV, Zacharatos P, Kastrinakis NG, et al. (2004) Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability-evidence of E2F-1 transcriptional control over hCdt1. Am J Pathol 165: 1351-1365.
    • (2004) Am J Pathol , vol.165 , pp. 1351-1365
    • Karakaidos, P.1    Taraviras, S.2    Vassiliou, L.V.3    Zacharatos, P.4    Kastrinakis, N.G.5
  • 78
    • 33748305620 scopus 로고    scopus 로고
    • Deregulation of Cdt1 induces chromosomal damage without rereplication and leads to chromosomal instability
    • Tatsumi Y, Sugimoto N, Yugawa T, Narisawa-Saito M, Kiyono T, et al. (2006) Deregulation of Cdt1 induces chromosomal damage without rereplication and leads to chromosomal instability. J Cell Sci 119: 3128-3140.
    • (2006) J Cell Sci , vol.119 , pp. 3128-3140
    • Tatsumi, Y.1    Sugimoto, N.2    Yugawa, T.3    Narisawa-Saito, M.4    Kiyono, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.