Inhibition of phenotypic and functional maturation of dendritic cells by manassantin A

Journal of Pharmacological Sciences

Volumn 109, Issue 4, 2009, Pages 583-592

  Kim, Jee Youn ^a   Kang, Jong Soon ^b   Kim, Hwan Mook ^b   Kim, Young Kook ^b   Lee, Hong Kyung ^a   Song, Sukgil ^a   Hong, Jin Tae ^a   Kim, Youngsoo ^a   Han, Sang Bae ^a  

^a Chungbuk National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Dendritic cell; Manassantin A; Maturation; Mitogen activated protein kinase; NF B

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MANASSANTIN A; MITOGEN ACTIVATED PROTEIN KINASE P38; PLANT EXTRACT; SAURURUS CERNUUS EXTRACT; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CELL FUNCTION; CELL MATURATION; CONTROLLED STUDY; DENDRITIC CELL; DRUG INHIBITION; FEMALE; GENE EXPRESSION; IMMUNE FUNCTION TEST; IMMUNOREACTIVITY; MEDICINAL PLANT; MOUSE; NONHUMAN; PHENOTYPE; SAURURUS CERNUUS; T LYMPHOCYTE;

EID: 66249087605     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.08299FP     Document Type: Article

References (37)

1. Grabbe S, Beissert S, Schwarz T, Granstein RD. Dendritic cells as initiators of tumor immune responses: a possible strategy for tumor immunotherapy? Immunol Today. 1995;16:117-121.
2. Lanzavecchia A. Identifying strategies for immune intervention. Science. 1993;260:937-944.
3. Schuler G, Steinman RM. Dendritic cells as adjuvants for immune-mediated resistance to tumors. J Exp Med. 1997;186: 1183-1187.
4. Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med. 1994;179:1109-1118.
5. Sallusto F, Cella M, Danieli C, Lanzavecchia A. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J Exp Med. 1995;182:389-400.
6. Neumann M, Fries H, Scheicher C, Keikavoussi P, Kolb-Maurer A, Brocker E, et al. Differential expression of Rel /NF-kappaB and octamer factors is a hallmark of the generation and maturation of dendritic cells. Blood. 2000;95:277-285.
7. Oyama T, Ran S, Ishida T, Nadaf S, Kerr L, Carbone DP, et al. Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-kappa B activation in hemopoietic progenitor cells. J Immunol. 1998;160:1224-1232.
8. Hehner SP, Heinrich M, Bork PM, Vogt M, Ratter F, Lehmann V, et al. Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta. J Biol Chem. 1998;273:1288-1297.
9. Hehner SP, Hofmann TG, Droge W, Schmitz ML. The antiinflammatory sesquiterpene lactone parthenolide inhibits NFkappa B by targeting the I kappa B kinase complex. J Immunol. 1999;163:5617-5623.
10. Kwon OE, Lee HS, Lee SW, Chung MY, Bae KH, Rho MC, et al. Manassantin A and B isolated from Saururus chinensis inhibit TNF-alpha-induced cell adhesion molecule expression of human umbilical vein endothelial cells. Arch Pharm Res. 2005;28:55-60.
11. Seo CS, Lee YK, Kim YJ, Jung JS, Jahng Y, Chang HW, et al. Protective effect of lignans against sepsis from the roots of Saururus chinensis. Biol Pharm Bull. 2008;31:523-526.
12. Kim JY, Yoon YD, Ahn JM, Kang JS, Park SK, Lee K, et al. Angelan isolated from Angelica gigas Nakai induces dendritic cell maturation through toll-like receptor 4. Int Immunopharmacol. 2007;7:78-87.
13. Han SB, Kim HM, Kim YH, Lee CW, Jang ES, Son KH, et al. T-cell specific immunosuppression by prodigiosin isolated from Serratia marcescens. Int J Immunopharmacol. 1998;20:1-13.
14. Dourado F, Madureira P, Carvalho V, Coelho R, Coimbra MA, Vilanova M, et al. Purification, structure and immunobiological activity of an arabinan-rich pectic polysaccharide from the cell walls of Prunus dulcis seeds. Carbohydr Res. 2004;339:2555-2566.
15. Lehner MD, Morath S, Michelsen KS, Schumann RR, Hartung T. Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators. J Immunol. 2001;166:5161-5167.
16. Yoon YD, Kang JS, Han SB, Park SK, Lee HS, Kang JS, et al. Activation of mitogen-activated protein kinases and AP-1 by polysaccharide isolated from the radix of Platycodon grandiflorum in RAW 264.7 cells. Int Immunopharmacol. 2004; 4:1477-1487.
17. Han SB, Moratz C, Huang NN, Kelsall B, Cho H, Shi CS, et al. Rgs1 and Gnai2 regulate the entrance of B lymphocytes into lymph nodes and B cell motility within lymph node follicles. Immunity. 2005;22:343-354.
18. Shlomchik WD, Couzens MS, Tang CB, McNiff J, Robert ME, Liu J, et al. Prevention of graft versus host disease by inactivation of host antigen-presenting cells. Science. 1999;285:412-415.
19. Ozaki Y, Amakawa R, Ito T, Iwai H, Tajima K, Uehira K, et al. Alteration of peripheral blood dendritic cells in patients with primary Sjogren's syndrome. Arthritis Rheum. 2001;44:419-431.
20. Vallin H, Perers A, Alm GV, Ronnblom L. Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN-alpha inducer in systemic lupus erythematosus. J Immunol. 1999;163:6306-6313.
21. Blanco P, Palucka AK, Gill M, Pascual V, Banchereau J. Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. Science. 2001;294:1540-1543.
22. Tajima K, Amakawa R, Ito T, Miyaji M, Takebayashi M, Fukuhara S. Immunomodulatory effects of cyclosporin A on human peripheral blood dendritic cell subsets. Immunology. 2003;108:321-328.
23. Xing N, ML LM, Bachman LA, McKean DJ, Kumar R, Griffin MD. Distinctive dendritic cell modulation by vitamin D(3) and glucocorticoid pathways. Biochem Biophys Res Commun. 2002; 297:645-652.
24. Lee JI, Ganster RW, Geller DA, Burckart GJ, Thomson AW, Lu L. Cyclosporine A inhibits the expression of costimulatory molecules on in vitro-generated dendritic cells: association with reduced nuclear translocation of nuclear factor kappa B. Transplantation. 1999;68:1255-1263.
25. Salgado CG, Nakamura K, Sugaya M, Tada Y, Asahina A, Fukuda S, et al. Differential effects of cytokines and immunosuppressive drugs on CD40, B7-1, and B7-2 expression on purified epidermal Langerhans cells1. J Invest Dermatol. 1999; 113:1021-1027.
26. Zhou LJ, Tedder TF. CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells. Proc Natl Acad Sci U S A. 1996;93:2588-2592.
27. Macatonia SE, Hosken NA, Litton M, Vieira P, Hsieh CS, Culpepper JA, et al. Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells. J Immunol. 1995;154:5071-5079.
28. Heufler C, Koch F, Stanzl U, Topar G, Wysocka M, Trinchieri G, et al. Interleukin-12 is produced by dendritic cells and mediates T helper 1 development as well as interferon-gamma production by T helper 1 cells. Eur J Immunol. 1996;26:659-668.
29. Grewal IS, Flavell RA. The role of CD40 ligand in costimulation and T-cell activation. Immunol Rev. 1996;153:85-106.
30. Gately MK, Renzetti LM, Magram J, Stern AS, Adorini L, Gubler U, et al. The interleukin-12 / interleukin-12-receptor system: role in normal and pathologic immune responses. Annu Rev Immunol. 1998;16:495-521.
31. Iwasaki A. Mucosal dendritic cells. Annu Rev Immunol. 2007; 25:381-418.
32. Klagge IM, Schneider-Schaulies S. Virus interactions with dendritic cells. J Gen Virol. 1999;80(Pt 4):823-833.
33. Fujii S, Liu K, Smith C, Bonito AJ, Steinman RM. The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation. J Exp Med. 2004;199:1607-1618.
34. Yoshimura S, Bondeson J, Foxwell BM, Brennan FM, Feldmann M. Effective antigen presentation by dendritic cells is NFkappaB dependent: coordinate regulation of MHC, costimulatory molecules and cytokines. Int Immunol. 2001;13: 675-683.
35. Hirata N, Yanagawa Y, Ebihara T, Seya T, Uematsu S, Akira S, et al. Selective synergy in anti-inflammatory cytokine production upon cooperated signaling via TLR4 and TLR2 in murine conventional dendritic cells. Mol Immunol. 2008;45:2734-2742.
36. Hwang BY, Lee JH, Nam JB, Hong YS, Lee JJ. Lignans from Saururus chinensis inhibiting the transcription factor NFkappaB. Phytochemistry. 2003;64:765-771.
37. Yamamoto Y, Gaynor RB. Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer. J Clin Invest. 2001;107:135-142.