Angelan isolated from Angelica gigas Nakai induces dendritic cell maturation through toll-like receptor 4

International Immunopharmacology

Volumn 7, Issue 1, 2007, Pages 78-87

  Kim, Jee Youn ^a,b   Yoon, Yeo Dae ^a   Ahn, Ji Mi ^a   Kang, Jong Soon ^a   Park, Song Kyu ^a   Lee, Kiho ^a   Song, Kyung Bin ^b   Kim, Hwan Mook ^a   Han, Sang Bae ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chungnam National University   (South Korea)

Author keywords

Angelan; Angelica gigas Nakai; Dendritic cells; Polysaccharides; Toll like receptor 4

Indexed keywords

ANGELAN; B7 ANTIGEN; CD86 ANTIGEN; HERBACEOUS AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOMODULATING AGENT; INTERLEUKIN 12; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MITOGEN ACTIVATED PROTEIN KINASE; POLYSACCHARIDE; TOLL LIKE RECEPTOR 4;

ANGELICA GIGAS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CELL MATURATION; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG ISOLATION; ENDOCYTOSIS; ENZYME ACTIVATION; FEMALE; IMMUNOPHARMACOLOGY; IMMUNOSTIMULATION; MEDICINAL PLANT; MELANOMA; MELANOMA CELL; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; T LYMPHOCYTE ACTIVATION; TREATMENT OUTCOME; TUMOR MODEL;

ANGELICA; ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; ENDOCYTOSIS; FEMALE; LYMPHOCYTE CULTURE TEST, MIXED; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; POLYSACCHARIDES; SPLEEN; T-LYMPHOCYTES; TOLL-LIKE RECEPTOR 4; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 33845292913     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2006.08.017     Document Type: Article

References (38)

1. Banchereau J., Briere F., Caux C., Davoust J., Lebecque S., et al. Immunobiology of dendritic cells. Annu Rev Immunol 18 (2000) 767-811
2. Nestle F.O., Alijagic S., Gilliet M., Sun Y., Grabbe S., et al. Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nat Med 4 (1998) 328-332
3. Hsu F.J., Benike C., Fagnoni F., Liles T.M., Czerwinski D., et al. Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nat Med 2 (1996) 52-58
4. Timmerman J.M., and Levy R. Dendritic cell vaccines for cancer immunotherapy. Annu Rev Med 50 (1999) 507-529
5. Rescigno M., Granucci F., Citterio S., Foti M., and Ricciardi-Castagnoli P. Coordinated events during bacteria-induced DC maturation. Immunol Today 20 (1999) 200-203
6. Hartmann G., Weiner G.J., and Krieg A.M. CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells. Proc Natl Acad Sci U S A 96 (1999) 9305-9310
7. Akbari O., Panjwani N., Garcia S., Tascon R., Lowrie D., et al. DNA vaccination: transfection and activation of dendritic cells as key events for immunity. J Exp Med 189 (1999) 169-178
8. Hacker H., Mischak H., Miethke T., Liptay S., Schmid R., et al. CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. EMBO J 17 (1998) 6230-6240
9. Aiba S., and Tagami H. Dendritic cell activation induced by various stimuli, e.g. exposure to microorganisms, their products, cytokines, and simple chemicals as well as adhesion to extracellular matrix. J Dermatol Sci 20 (1998) 1-13
10. Manome H., Aiba S., and Tagami H. Simple chemicals can induce maturation and apoptosis of dendritic cells. Immunology 98 (1999) 481-490
11. Han S.B., Yoon Y.D., Ahn H.J., Lee H.S., Lee C.W., et al. Toll-like receptor-mediated activation of B cells and macrophages by polysaccharide isolated from cell culture of Acanthopanax senticosus. Int Immunopharmacol 3 (2003) 1301-1312
12. Modlin R.L. Mammalian toll-like receptors. Ann Allergy Asthma Immunol 88 (2002) 543-547 quiz 548-50, 583
13. Lehner M.D., Morath S., Michelsen K.S., Schumann R.R., and Hartung T. Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators. J Immunol 166 (2001) 5161-5167
14. Dourado F., Madureira P., Carvalho V., Coelho R., Coimbra M.A., et al. Purification, structure and immunobiological activity of an arabinan-rich pectic polysaccharide from the cell walls of Prunus dulcis seeds. Carbohydr Res 339 (2004) 2555-2566
15. Kim G.Y., Oh W.K., Shin B.C., Shin Y.I., Park Y.C., et al. Proteoglycan isolated from Phellinus linteus inhibits tumor growth through mechanisms leading to an activation of CD11c+ CD8+ DC and type I helper T cell-dominant immune state. FEBS Lett 576 (2004) 391-400
16. Kim G.Y., Han M.G., Song Y.S., Shin B.C., Shin Y.I., et al. Proteoglycan isolated from Phellinus linteus induces toll-like receptors 2- and 4-mediated maturation of murine dendritic cells via activation of ERK, p38, and NF-kappaB. Biol Pharm Bull 27 (2004) 1656-1662
17. Park S.K., Kim G.Y., Lim J.Y., Kwak J.Y., Bae Y.S., et al. Acidic polysaccharides isolated from Phellinus linteus induce phenotypic and functional maturation of murine dendritic cells. Biochem Biophys Res Commun 312 (2003) 449-458
18. Kim G.Y., Lee M.Y., Lee H.J., Moon D.O., Lee C.M., et al. Effect of water-soluble proteoglycan isolated from Agaricus blazei on the maturation of murine bone marrow-derived dendritic cells. Int Immunopharmacol 5 (2005) 1523-1532
19. Kanazawa M., Mori Y., Yoshihara K., Iwadate M., Suzuki S., et al. Effect of PSK on the maturation of dendritic cells derived from human peripheral blood monocytes. Immunol Lett 91 (2004) 229-238
20. Kim G.Y., Ko W.S., Lee J.Y., Lee J.O., Ryu C.H., et al. Water extract of Cordyceps militaris enhances maturation of murine bone marrow-derived dendritic cells in vitro. Biol Pharm Bull 29 (2006) 354-360
21. Lee J.K., Lee M.K., Yun Y.P., Kim Y., Kim J.S., et al. Acemannan purified from Aloe vera induces phenotypic and functional maturation of immature dendritic cells. Int Immunopharmacol 1 (2001) 1275-1284
22. Han S.B., Kim Y.H., Lee C.W., Park S.M., Lee H.Y., et al. Characteristic immunostimulation by angelan isolated from Angelica gigas Nakai. Immunopharmacology 40 (1998) 39-48
23. Han S.B., Lee C.W., Kang M.R., Yoon Y.D., Kang J.S., et al. Pectic polysaccharide isolated from Angelica gigas Nakai inhibits melanoma cell metastasis and growth by directly preventing cell adhesion and activating host immune functions. Cancer Lett (2006) Equb ahead of print
24. Jeon Y.J., Han S.B., Ahn K.S., and Kim H.M. Activation of NF-kappaB/Rel in angelan-stimulated macrophages. Immunopharmacology 43 (1999) 1-9
25. Shi G.X., Harrison K., Han S.B., Moratz C., and Kehrl J.H. Toll-like receptor signaling alters the expression of regulator of G protein signaling proteins in dendritic cells: implications for G protein-coupled receptor signaling. J Immunol 172 (2004) 5175-5184
26. Yoon Y.D., Kang J.S., Han S.B., Park S.K., Lee H.S., et al. Activation of mitogen-activated protein kinases and AP-1 by polysaccharide isolated from the radix of Platycodon grandiflorum in RAW 264.7 cells. Int Immunopharmacol 4 (2004) 1477-1487
27. Yoon Y.D., Han S.B., Kang J.S., Lee C.W., Park S.K., et al. Toll-like receptor 4-dependent activation of macrophages by polysaccharide isolated from the radix of Platycodon grandiflorum. Int Immunopharmacol 3 (2003) 1873-1882
28. Han S.B., Moratz C., Huang N.N., Kelsall B., Cho H., et al. Rgs1 and Gnai2 regulate the entrance of B lymphocytes into lymph nodes and B cell motility within lymph node follicles. Immunity 22 (2005) 343-354
29. Huang N.N., Han S.B., Hwang I.Y., and Kehrl J.H. B cells productively engage soluble antigen-pulsed dendritic cells: visualization of live-cell dynamics of B cell-dendritic cell interactions. J Immunol 175 (2005) 7125-7134
30. Granucci F., Ferrero E., Foti M., Aggujaro D., Vettoretto K., et al. Early events in dendritic cell maturation induced by LPS. Microbes Infect 1 (1999) 1079-1084
31. Leung M.Y., Liu C., Koon J.C., and Fung K.P. Polysaccharide biological response modifiers. Immunol Lett (2006)
32. Shao B.M., Dai H., Xu W., Lin Z.B., and Gao X.M. Immune receptors for polysaccharides from Ganoderma lucidum. Biochem Biophys Res Commun 323 (2004) 133-141
33. Shao B.M., Xu W., Dai H., Tu P., Li Z., et al. A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb. Biochem Biophys Res Commun 320 (2004) 1103-1111
34. Han S.B., Park S.K., Ahn H.J., Yoon Y.D., Kim Y.H., et al. Characterization of B cell membrane receptors of polysaccharide isolated from the root of Acanthopanax koreanum. Int Immunopharmacol 3 (2003) 683-691
35. Fu S.L., Hsu Y.H., Lee P.Y., Hou W.C., Hung L.C., et al. Dioscorin isolated from Dioscorea alata activates TLR4-signaling pathways and induces cytokine expression in macrophages. Biochem Biophys Res Commun 339 (2006) 137-144
36. Kim Y.O., Han S.B., Lee H.W., Ahn H.J., Yoon Y.D., et al. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus. Life Sci 77 (2005) 2438-2456
37. Jeon Y.J., Han S.B., Ahn K.S., and Kim H.M. Differential activation of murine macrophages by angelan and LPS. Immunopharmacology 49 (2000) 275-284
38. Kim H.M., Han S.B., Oh G.T., Kim Y.H., Hong D.H., et al. Stimulation of humoral and cell mediated immunity by polysaccharide from mushroom Phellinus linteus. Int J Immunopharmacol 18 (1996) 295-303