Alternatively activated RAW264.7 macrophages enhance tumor lymphangiogenesis in mouse lung adenocarcinoma

Journal of Cellular Biochemistry

Volumn 107, Issue 1, 2009, Pages 134-143

  Zhang, Bicheng ^a,b   Wang, Jun ^b,c   Gao, Juan ^a   Guo, Yan ^b   Chen, Xi ^b   Wang, Baocheng ^c   Gao, Jianfei ^a   Rao, Zhiguo ^a   Chen, Zhengtang ^b  

^a WUHAN GENERAL HOSPITAL OF GUANGZHOU COMMAND   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

^c JINAN MILITARY GENERAL HOSPITAL   (China)

Author keywords

Alternative activation; LECs; Lymphangiogenesis; Tumor associated macrophages; VEGF C

Indexed keywords

CHIMERIC PROTEIN; GAMMA INTERFERON; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PROX 1; UNCLASSIFIED DRUG; VASCULOTROPIN C; VASCULOTROPIN D; VASCULOTROPIN RECEPTOR 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER INVASION; CANCER SURVIVAL; CAPILLARY; CELL MIGRATION; CELL PROLIFERATION; COCULTURE; CONTROLLED STUDY; DISTANT METASTASIS; ENDOTHELIUM CELL; FEMALE; INOCULATION; LEWIS CARCINOMA; LYMPH NODE METASTASIS; LYMPH VESSEL ENDOTHELIUM; LYMPHANGIOGENESIS; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR GENE; TUMOR PROMOTION; TUMOR VASCULARIZATION;

ANIMALS; BLOTTING, WESTERN; CARCINOMA, LEWIS LUNG; CELL MOVEMENT; COCULTURE TECHNIQUES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOHISTOCHEMISTRY; LYMPHANGIOGENESIS; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL; NEOPLASM INVASIVENESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIAL GROWTH FACTOR C;

MUS;

EID: 66149170239     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22110     Document Type: Article

References (51)

1. Allavena P, Sica A, Garlanda C, Mantovani A. 2008. The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance. Immunol Rev 222:155-161.
2. Alitalo K, Tammela T, Petrova TV. 2005. Lymphangiogenesis in development and human disease. Nature 438:946-953.
3. Anderson CA, Mosser DM. 2002. A novel phenotype for activated macrophages: The type II activated macrophage. J Leukoc Biol 72:101-106.
4. Avraamides CJ, Garmy-Susini B, Varner JA. 2008. Integrins in angiogenesis and lymphangiogenesis. Nat Rev Cancer 8:604-617.
5. Bailey C, Negus R, Morris A, Ziprin P, Goldin R, Allavena P, Peck D, Darzi A. 2007. Chemokine expression is associated with the accumulation of tumour associated macrophages (TAMs) and progression in human colorectal cancer. Clin Exp Metastasis 24:121-130.
6. Bobek V, Kolostova K, Pinterov D, Boubelik M, Jiang P, Yang M, Hoffman RM. 2004. Syngeneic lymph-node-targeting model of green fluorescent protein-expressing Lewis lung carcinoma. Clin Exp Metastasis 21:705-708.
7. Chen JJ, Lin YC, Yao PL, Yuan A, Chen HY, Shun CT, Tsai MF, Chen CH, Yang PC. 2005. Tumor-associated macrophages: The double-edged sword in cancer progression. J Clin Oncol 23:953-964.
8. Colombo MP, Mantovani A. 2005. Targeting myelomonocytic cells to revert inflammation-dependent cancer promotion. Cancer Res 65:9113-9116.
9. Craig M, Ying C, Loberg RD. 2008. Co-inoculation of prostate cancer cells with U937 enhances tumor growth and angiogenesis in vivo. J Cell Biochem 103:1-8.
10. Edwards JP, Zhang X, Frauwirth KA, Mosser DM. 2006. Biochemical and functional characterization of three activated macrophage populations. J Leukoc Biol 80:1298-1307.
11. Ghosh D, Maiti TK. 2007. Effects of native and heat-denatured Abrus agglutinin on tumor-associated macrophages in Dalton's lymphoma mice. Immunobiology 212:667-673.
12. Gordon S. 2003. Alternative activation of macrophages. Nat Rev Immunol 3:23-35.
13. Gratchev A, Guillot P, Hakiy N, Politz O, Orfanos CE, Schledzewski K, Goerdt S. 2001. Alternatively activated macrophages differentially express fibronectin and its splice variants and the extracellular matrix protein betaIG-H3. Scand J Immunol 53:386-392.
14. Gratchev A, Kzhyshkowska J, Köthe K, Muller-Molinet I, Kannookadan S, Utikal J, Goerdt S. 2006. Mphi1 and Mphi2 can be re-polarized by Th2 or Th1 cytokines, respectively, and respond to exogenous danger signals. Immunobiology 211:473-486.
15. Guiducci C, Vicari AP, Sangaletti S, Trinchieri G, Colombo MP. 2005. Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection. Cancer Res 65:3437-3446.
16. Hagemann T, Wilson J, Burke F, Kulbe H, Li NF, Plüddemann A, Charles K, Gordon S, Balkwill FR. 2006. Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype. J Immunol 176:5023-5032.
17. Kerjaschki D. 2005. The crucial role of macrophages in lymphangiogenesis. J Clin Invest 115:2316-2319.
18. Kumar S, Deepak P, Acharya A. 2007. Hsp70 induces Th1 polarization through tumor-associated macrophages in a T-cell lymphoma. Neoplasma 54:113-122.
19. Lewis CE, Pollard JW. 2006. Distinct role of macrophages in different tumor microenvironments. Cancer Res 66:605-612.
20. Luo Y, Zhou H, Krueger J, Kaplan C, Lee SH, Dolman C, Markowitz D, Wu W, Liu C, Reisfeld RA, Xiang R. 2006. Targeting tumor-associated macrophages as a novel strategy against breast cancer. J Clin Invest 116:2132-2141.
21. Mandriota SJ, Jussila L, Jeltsch M, Compagni A, Baetens D, Prevo R, Banerji S, Huarte J, Montesano R, Jackson DG, Orci L, Alitalo K, Christofori G, Pepper MS. 2001. Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J 20:672-682.
22. Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. 2002. Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23:549-555.
23. Mantovani A, Sozzani S, Locati M, Schioppa T, Saccani A, Allavena P, Sica A. 2004a. Infiltration of tumours by macrophages and dendritic cells: Tumour-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Novartis Found Symp 256:137-145.
24. Mantovani A, Allavena P, Sica A. 2004b. Tumour-associated macrophages as a prototypic type II polarised phagocyte population: Role in tumour progression. Eur J Cancer 40:1660-1667.
25. Mantovani A, Schioppa T, Porta C, Allavena P, Sica A. 2006. Role of tumorassociated macrophages in tumor progression and invasion. Cancer Metastasis Rev 25:315-322.
26. Martinez FO, Sica A, Mantovani A, Locati M. 2008. Macrophage activation and polarization. Front Biosci 13:453-461.
27. Maruyama K, Ii M, Cursiefen C, Jackson DG, Keino H, Tomita M, Van Rooijen N, Takenaka H, D'Amore PA, Stein-Streilein J, Losordo DW, Streilein JW. 2005. Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages. J Clin Invest 115:2363-2372.
28. Mosser DM. 2003. The many faces of macrophage activation. J Leukoc Biol 73:209-212.
29. Mouta Carreira C, Nasser SM, di Tomaso E, Padera TP, Boucher Y, Tomarev SI, Jain RK. 2001. LYVE-1 is not restricted to the lymph vessels: Expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis. Cancer Res 61:8079-8084.
30. Ochi N, Matsuo Y, Sawai H, Yasuda A, Takahashi H, Sato M, Funahashi H, Okada Y, Manabe T. 2007. Vascular endothelial growth factor-C secreted by pancreatic cancer cell line promotes lymphatic endothelial cell migration in an in vitro model of tumor lymphangiogenesis. Pancreas 34:444-451.
31. Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R, Carey VJ, Richardson AL, Weinberg RA. 2005. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121:335-348.
32. Pollard JW. 2004. Tumour-educated macrophages promote tumor progression and metastasis. Nat Rev Cancer 4:71-78.
33. Porta C, Mantovani A. 2008. The inflammatory micro-environment in tumor progression: The role of tumor-associated macrophages. Crit Rev Oncol Hematol 66:1-9.
34. Porta C, Subhra Kumar B, Larghi P, Rubino L, Mancino A, Sica A. 2007. Tumor promotion by tumor-associated macrophages. Adv Exp Med Biol 604:67-86.
35. Ristimäki A, Narko K, Enholm B, Joukov V, Alitalo K. 1998. Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C. J Biol Chem 272:8413-8418.
36. Schneider M, Büchler P, Giese N, Giese T, Wilting J, Büchler MW, Friess H. 2006. Role of lymphangiogenesis and lymphangiogenic factors during pancreatic cancer progression and lymphatic spread. Int J Oncol 28:883-890.
37. Schoppmann SF, Birner P, Stöckl J, Kalt R, Ullrich R, Caucig C, Kriehuber E, Nagy K, Alitalo K, Kerjaschki D. 2002. Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis. Am J Pathol 161:947-956.
38. Schoppmann SF, Fenzl A, Nagy K, Unger S, Bayer G, Geleff S, Gnant M, Horvat R, Jakesz R, Birner P. 2006. VEGF-C expressing tumor-associated macrophages in lymph node positive breast cancer: Impact on lymphangiogenesis and survival. Surgery 139:839-846.
39. Sica A, Rubino L, Mancino A, Larghi P, Porta C, Rimoldi M, Solinas G, Locati M, Allavena P, Mantovani A. 2007. Targeting tumour-associated macrophages. Expert Opin Ther Targets 11:1219-1229.
40. Soumaoro LT, Uetake H, Takagi Y, Iida S, Higuchi T, Yasuno M, Enomoto M, Sugihara K. 2006. Coexpression of VEGF-C and Cox-2 in human colorectal cancer and its association with lymph node metastasis. Dis Colon Rectum 49:392-398.
41. Stacker SA, Caesar C, Baldwin ME, Thornton GE, Williams RA, Prevo R, Jackson DG, Nishikawa S, Kubo H, Achen MG. 2001. Vascular endothelial growth factor-D promotes the metastatic spread of cancer via the lymphatics. Nature Med 7:186-191.
42. Stacker SA, Farnsworth RH, Karnezis T, Shayan R, Smith DP, Paavonen K, Davydova N, Caesar C, Inder R, Baldwin ME, McColl BK, Roufail S, Williams RA, Hughes RA, Alitalo K, Achen MG. 2007. Molecular pathways for lymphangiogenesis and their role in human disease. Novartis Found Symp 281:38-43.
43. Stein M, Keshav S, Harris N, Gordon S. 1992. Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation. J Exp Med 176:287-292.
44. Takanami I, Takeuchi K, Kodaira S. 1998. Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: Association with angiogenesis and poor prognosis. Oncology 57:138-142.
45. Tang RF, Wang SX, Zhang FR, Peng L, Wang SX, Xiao Y, Zhang M. 2005. Interleukin-1alpha, 6 regulate the secretion of vascular endothelial growth factor A, C in pancreatic cancer. Hepatobiliary Pancreat Dis Int 4:460-463.
46. Varney ML, Olsen KJ, Mosley RL, Singh RK. 2005. Paracrine regulation of vascular endothelial growth factor-a expression during macrophage-melanoma cell interaction: Role of monocyte chemotactic protein-1 and macrophage colony-stimulating factor. J Interferon Cytokine Res 25:674-683.
47. Vicioso L, Gonzalez FJ, Alvarez M, Ribelles N, Molina M, Marquez A, Perez L, Matilla A, Alba E. 2006. Elevated serum levels of vascular endothelial growth factor are associated with tumor-associated macrophages in primary breast cancer. Am J Clin Pathol 125:111-118.
48. Wang J, Guo Y, Zhang BC, Chen ZT, Gao JF. 2007. Induction of apoptosis and inhibition of cell migration and tube-like formation by dihydroartemisinin in murine lymphatic endothelial cells. Pharmacology 80:207-218.
49. Wang J, Zhang B, Guo Y, Li G, Xie Q, Zhu B, Gao J, Chen Z. 2008. Artemisinin inhibits tumor lymphangiogenesis by suppression of vascular endothelial growth factor C. Pharmacology 82:148-155.
50. Watari K, Nakao S, Fotovati A, Basaki Y, Hosoi F, Bereczky B, Higuchi R, Miyamoto T, Kuwano M, Ono M. 2008. Role of macrophages in inflammatory lymphangiogenesis: Enhanced production of vascular endothelial growth factor C and D through NF-kappaB activation. Biochem Biophys Res Commun 377:826-831.
51. Yao PL, Lin YC, Wang CH, Huang YC, Liao WY, Wang SS, Chen JJ, Yang PC. 2005. Autocrine and paracrine regulation of interleukin-8 expression in lung cancer cells. Am J Respir Cell Mol Biol 32:540-547.