-
1
-
-
0031905861
-
Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)
-
Achen MG, Jeltsch M, Kukk E et al 1998 Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). Proc Natl Acad Sci USA 95:548-553.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 548-553
-
-
Achen, M.G.1
Jeltsch, M.2
Kukk, E.3
-
4
-
-
0033593793
-
+ glycoprotein, is a lymph-specific receptor for hyaluronan
-
+ glycoprotein, is a lymph-specific receptor for hyaluronan. J Cell Biol 144:789-801.
-
(1999)
J Cell Biol
, vol.144
, pp. 789-801
-
-
Banerji, S.1
Ni, J.2
Wang, S.-X.3
-
5
-
-
0032582502
-
Cardiovascular failure in mouse embryos deficient in VEGF receptor-3
-
Dumont DJ, Jussila L, Taipale J et al 1998 Cardiovascular failure in mouse embryos deficient in VEGF receptor-3. Science 282:946-949.
-
(1998)
Science
, vol.282
, pp. 946-949
-
-
Dumont, D.J.1
Jussila, L.2
Taipale, J.3
-
6
-
-
21144437844
-
Vascular endothelial cell growth factor receptor 3- mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels
-
He Y, Rajantie I, Pajusola K et al 2005 Vascular endothelial cell growth factor receptor 3- mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels. Cancer Res 65:4739-4746.
-
(2005)
Cancer Res
, vol.65
, pp. 4739-4746
-
-
He, Y.1
Rajantie, I.2
Pajusola, K.3
-
7
-
-
17144402207
-
VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis
-
Hirakawa S, Kodama S, Kunstfeld R, Kajiya K, Brown LF, Detmar M 2005 VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis. J Exp Med 201:1089-1099.
-
(2005)
J Exp Med
, vol.201
, pp. 1089-1099
-
-
Hirakawa, S.1
Kodama, S.2
Kunstfeld, R.3
Kajiya, K.4
Brown, L.F.5
Detmar, M.6
-
8
-
-
0034913816
-
LYVE-1, the lymphatic system and tumor lymphangiogenesis
-
Jackson DG, Prevo R, Clasper S, Banerji S 2001 LYVE-1, the lymphatic system and tumor lymphangiogenesis. Trends Immunol 22:317-321.
-
(2001)
Trends Immunol
, vol.22
, pp. 317-321
-
-
Jackson, D.G.1
Prevo, R.2
Clasper, S.3
Banerji, S.4
-
9
-
-
0030973506
-
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
-
Jeltsch M, Kaipainen A, Joukov V et al 1997 Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science 276:1423-1425.
-
(1997)
Science
, vol.276
, pp. 1423-1425
-
-
Jeltsch, M.1
Kaipainen, A.2
Joukov, V.3
-
10
-
-
0030026897
-
A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
-
Joukov V, Pajusola K, Kaipainen A et al 1996 A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J 15:290-298.
-
(1996)
EMBO J
, vol.15
, pp. 290-298
-
-
Joukov, V.1
Pajusola, K.2
Kaipainen, A.3
-
11
-
-
0031011529
-
Proteolytic processing regulates receptor specificity and activity of VEGF-C
-
Joukov V, Sorsa T, Kumar V et al 1997 Proteolytic processing regulates receptor specificity and activity of VEGF-C. EMBO J 16:3898-3911.
-
(1997)
EMBO J
, vol.16
, pp. 3898-3911
-
-
Joukov, V.1
Sorsa, T.2
Kumar, V.3
-
12
-
-
20544471876
-
Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
-
Kabbinavar FF, Hambleton J, Mass RD, Hurwitz HI, Bergsland E, Sarkar S 2005 Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer. J Clin Oncol 23:3706-3712.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3706-3712
-
-
Kabbinavar, F.F.1
Hambleton, J.2
Mass, R.D.3
Hurwitz, H.I.4
Bergsland, E.5
Sarkar, S.6
-
13
-
-
30544452034
-
Hepatocyte growth factor promotes lymphatic vessel formation and function
-
Kajiya K, Hirakawa S, Ma B, Drinnenberg I, Detmar M 2005 Hepatocyte growth factor promotes lymphatic vessel formation and function. EMBO J 24:2885-2895.
-
(2005)
EMBO J
, vol.24
, pp. 2885-2895
-
-
Kajiya, K.1
Hirakawa, S.2
Ma, B.3
Drinnenberg, I.4
Detmar, M.5
-
14
-
-
0034041161
-
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
-
Karkkainen MJ, Ferrell RE, Lawrence EC et al 2000 Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema. Nat Genet 25:153-159.
-
(2000)
Nat Genet
, vol.25
, pp. 153-159
-
-
Karkkainen, M.J.1
Ferrell, R.E.2
Lawrence, E.C.3
-
15
-
-
9144236286
-
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
-
Karkkainen MJ, Haiko P, Sainio K et al 2004 Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol 5:74-80.
-
(2004)
Nat Immunol
, vol.5
, pp. 74-80
-
-
Karkkainen, M.J.1
Haiko, P.2
Sainio, K.3
-
16
-
-
0035266283
-
Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth
-
Karpanen T, Egeblad M, Karkkainen MJ et al 2001 Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth. Cancer Res 61:1786-1790.
-
(2001)
Cancer Res
, vol.61
, pp. 1786-1790
-
-
Karpanen, T.1
Egeblad, M.2
Karkkainen, M.J.3
-
17
-
-
0242624291
-
Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3
-
Makinen T, Veikkola T, Mustjoki S et al 2001a Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3. EMBO J 20:4762-4773.
-
(2001)
EMBO J
, vol.20
, pp. 4762-4773
-
-
Makinen, T.1
Veikkola, T.2
Mustjoki, S.3
-
18
-
-
0035122695
-
Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3
-
Makinen T, Jussila L, Veikkola, T et al 2001b Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. Nat Med 7:199-205.
-
(2001)
Nat Med
, vol.7
, pp. 199-205
-
-
Makinen, T.1
Jussila, L.2
Veikkola, T.3
-
19
-
-
17744390184
-
Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis
-
Mandriota SJ, Jussila L, Jeltsch M et al 2001 Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J 20:672-682.
-
(2001)
EMBO J
, vol.20
, pp. 672-682
-
-
Mandriota, S.J.1
Jussila, L.2
Jeltsch, M.3
-
20
-
-
0141672945
-
Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D
-
McColl BK, Baldwin ME, Roufail S et al 2003 Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D. J Exp Med 198:863-868.
-
(2003)
J Exp Med
, vol.198
, pp. 863-868
-
-
McColl, B.K.1
Baldwin, M.E.2
Roufail, S.3
-
21
-
-
0036208217
-
The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature
-
Oliver G, Detmar M 2002 The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature. Genes Dev 16:773-783.
-
(2002)
Genes Dev
, vol.16
, pp. 773-783
-
-
Oliver, G.1
Detmar, M.2
-
22
-
-
0037036136
-
Lymphatic metastasis in the absence of functional intratumor lymphatics
-
Padera TP, Kadambi A, di Tomaso E et al 2002 Lymphatic metastasis in the absence of functional intratumor lymphatics. Science 296:1883-1886.
-
(2002)
Science
, vol.296
, pp. 1883-1886
-
-
Padera, T.P.1
Kadambi, A.2
di Tomaso, E.3
-
23
-
-
0038481179
-
The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis
-
Siegfried G, Basak A, Cromlish JA 2003 The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis. J Clin Invest 111:1723-1732.
-
(2003)
J Clin Invest
, vol.111
, pp. 1723-1732
-
-
Siegfried, G.1
Basak, A.2
Cromlish, J.A.3
-
24
-
-
0035122537
-
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis
-
Skobe M, Hawighorst T, Jackson DG et al 2001 Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nat Med 7:192-198.
-
(2001)
Nat Med
, vol.7
, pp. 192-198
-
-
Skobe, M.1
Hawighorst, T.2
Jackson, D.G.3
-
25
-
-
0033527634
-
Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers
-
Stacker SA, Stenvers K, Caesar C et al 1999 Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers. J Biol Chem 274:32127-32136.
-
(1999)
J Biol Chem
, vol.274
, pp. 32127-32136
-
-
Stacker, S.A.1
Stenvers, K.2
Caesar, C.3
-
26
-
-
0035126049
-
VEGF-D promotes the metastatic spread of tumor cells via the lymphatics
-
Stacker SA, Caesar C, Baldwin ME et al 2001 VEGF-D promotes the metastatic spread of tumor cells via the lymphatics. Nat Med 7:186-191.
-
(2001)
Nat Med
, vol.7
, pp. 186-191
-
-
Stacker, S.A.1
Caesar, C.2
Baldwin, M.E.3
-
27
-
-
0036673666
-
Lymphangiogenesis and cancer metastasis
-
Stacker SA, Achen MG, Jussila L, Baldwin ME, Alitalo K 2002 Lymphangiogenesis and cancer metastasis. Nat Rev Cancer 2:573-583.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 573-583
-
-
Stacker, S.A.1
Achen, M.G.2
Jussila, L.3
Baldwin, M.E.4
Alitalo, K.5
-
29
-
-
10344237560
-
Lymphangiogenic growth factors as markers of tumor metastasis
-
Stacker SA, Williams RA, Achen MG 2004b Lymphangiogenic growth factors as markers of tumor metastasis. APMIS 112:539-549.
-
(2004)
APMIS
, vol.112
, pp. 539-549
-
-
Stacker, S.A.1
Williams, R.A.2
Achen, M.G.3
-
30
-
-
17744396472
-
Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice
-
Veikkola T, Jussila L, Makinen T et al 2001 Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice. EMBO J 20:1223-1231.
-
(2001)
EMBO J
, vol.20
, pp. 1223-1231
-
-
Veikkola, T.1
Jussila, L.2
Makinen, T.3
-
31
-
-
0037086278
-
Vascular endothelial growth factor-D expression is an independent prognostic marker for survival in colorectal carcinoma
-
White JD, Hewett PW, Kosuge D et al 2002 Vascular endothelial growth factor-D expression is an independent prognostic marker for survival in colorectal carcinoma. Cancer Res 62:1669-1675.
-
(2002)
Cancer Res
, vol.62
, pp. 1669-1675
-
-
White, J.D.1
Hewett, P.W.2
Kosuge, D.3
-
32
-
-
0037468102
-
Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma
-
Yokoyama Y, Charnock-Jones DS, Licence D et al 2003 Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma. Br J Cancer 88:237-244.
-
(2003)
Br J Cancer
, vol.88
, pp. 237-244
-
-
Yokoyama, Y.1
Charnock-Jones, D.S.2
Licence, D.3
-
33
-
-
28644432204
-
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
-
Kaplan RN, Riba RD, Zacharoulis S et al 2005 VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 438:820-827.
-
(2005)
Nature
, vol.438
, pp. 820-827
-
-
Kaplan, R.N.1
Riba, R.D.2
Zacharoulis, S.3
-
34
-
-
24644474779
-
Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages
-
Maruyama K, Ii M, Cursiefen C et al 2005 Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages. J Clin Invest 115:2363-2372.
-
(2005)
J Clin Invest
, vol.115
, pp. 2363-2372
-
-
Maruyama, K.1
Ii, M.2
Cursiefen, C.3
|