Chronic hypoxia attenuates VEGF signaling and angiogenic responses by downregulation of KDR in human endothelial cells

American Journal of Physiology - Cell Physiology

Volumn 296, Issue 5, 2009, Pages

  Olszewska Pazdrak, Barbara ^a   Hein, Travis W ^b   Olszewska, Paulina ^a   Carney, Darrell H ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b SCOTT AND WHITE MEMORIAL HOSPITAL   (United States)

Author keywords

Angiogenesis; Endothelial dysfunction; Endothelial nitric oxide synthase; Ischemia

Indexed keywords

NITRIC OXIDE SYNTHASE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HYPOXIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADULT; ANOXIA; CAPILLARIES; CELL DIVISION; CELL MOVEMENT; CELLS, CULTURED; CHRONIC DISEASE; CORONARY VESSELS; DOWN-REGULATION; ENDOTHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; HUMANS; MYOCARDIAL ISCHEMIA; NEOVASCULARIZATION, PHYSIOLOGIC; NITRIC OXIDE SYNTHASE TYPE III; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 66149137539     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00533.2008     Document Type: Article

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