An activating mutation in the pdgf receptor alpha results in embryonic lethality caused by malformation of the vascular system

Developmental Dynamics

Volumn 238, Issue 5, 2009, Pages 1064-1072

  Kurth, Patricia ^b   Moenning, Anne ^a   Jäger, Richard ^a   Beine, Gaby ^a   Schorle, Hubert ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

Autoactivation; Gt(ROSA)26Sortm1(PDGFRA*)Hsc; PDGFR ; Transgenic mice; Vascular system

Indexed keywords

PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR MALFORMATION; CARDIOVASCULAR SYSTEM; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GENE MUTATION; MESENCHYME CELL; MOUSE; NEURAL TUBE DEFECT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; EMBRYO LOSS; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; MICE; MICE, TRANSGENIC; MUSCLE, SMOOTH, VASCULAR; MUTATION; NEURAL TUBE DEFECTS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA;

ANIMALIA; MUS MUSCULUS;

EID: 66149128866     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.21939     Document Type: Article

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