Inflammation-induced, 3′UTR-dependent translational inhibition of Hsp70 mRNA impairs intestinal homeostasis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 296, Issue 5, 2009, Pages

  Hu, Shien ^a   Zhu, Xiaorong ^a   Triggs, Joseph R ^a   Tao, Yun ^a   Wang, Yunwei ^a   Lichtenstein, Lev ^a,b   Bissonnette, Marc ^a   Musch, Mark W ^a   Chang, Eugene B ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b RABIN MEDICAL CENTER   (Israel)

Author keywords

3 untranslated region; Dextran sodium sulfate; Heat shock protein 70

Indexed keywords

HEAT SHOCK PROTEIN 70; MESSENGER RNA; VILLIN; CYTOKINE; DEXTRAN SULFATE;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; COLITIS; DISEASE SEVERITY; DOWN REGULATION; HOMEOSTASIS; INFLAMMATION; INTESTINE EPITHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; TRANSLATION REGULATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL LINE; CHEMICALLY INDUCED DISORDER; COLON; DISEASE MODEL; GENETIC TRANSFECTION; GENETICS; HOSPITALIZATION; INTESTINE MUCOSA; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PROTEIN SYNTHESIS; REPORTER GENE; TIME;

3' UNTRANSLATED REGIONS; ANIMALS; CELL LINE; COLITIS; COLON; CYTOKINES; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; GENES, REPORTER; HOMEOSTASIS; HSP70 HEAT-SHOCK PROTEINS; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROTEIN BIOSYNTHESIS; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TRANSFECTION;

EID: 66149088058     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00027.2009     Document Type: Article

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