Hypoxia up-regulates vascular endothelial growth factor in U-87 MG cells: Involvement of TRPC1

Neuroscience Letters

Volumn 459, Issue 3, 2009, Pages 132-136

  Wang, Bin ^a   Li, Wenjun ^a   Meng, Xiaojing ^a   Zou, Fei ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Glioblastomas; Hypoxia; TRPC; VEGF

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; BETA ACTIN; MESSENGER RNA; SMALL INTERFERING RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; TRANSIENT RECEPTOR POTENTIAL CHANNEL 4; TRANSIENT RECEPTOR POTENTIAL CHANNEL 5; VASCULOTROPIN;

ARTICLE; CELL HYPOXIA; CONTROLLED STUDY; DRUG MECHANISM; GENE OVEREXPRESSION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; HYPOXIA; PRIORITY JOURNAL; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; UPREGULATION;

CALCIUM CHANNEL BLOCKERS; CELL HYPOXIA; CELL LINE, TUMOR; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMIDAZOLES; MICROSCOPY, FLUORESCENCE; OXYGEN; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSFECTION; TRPC CATION CHANNELS; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 66049160528     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.05.015     Document Type: Article

References (26)

1. Aarts M., Iihara K., Wei W.L., Xiong Z.G., Arundine M., Cerwinski W., MacDonald J.F., and Tymianski M. A key role for TRPM7 channels in anoxic neuronal death. Cell 115 (2003) 863-877
2. Abramowitz J., and Birnbaumer L. Physiology and pathophysiology of canonical transient receptor potential channels. FASEB J. 23 (2009) 297-328
3. Alicia S., Angelica Z., Carlos S., Alfonso S., and Vaca L. STIM1 converts TRPC1 from a receptor-operated to a store-operated channel: moving TRPC1 in and out of lipid rafts. Cell Calcium 44 (2008) 479-491
4. Ding H., Roncari L., Wu X., Lau N., Shannon P., Nagy A., and Guha A. Expression and hypoxic regulation of angiopoietins in human astrocytomas. Neuro-oncol. 3 (2001) 1-10
5. 2+ entry in human pulmonary artery endothelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 285 (2003) L1233-1245
6. Fisher P.G., and Buffler P.A. Malignant gliomas in 2005: where to GO from here?. JAMA 293 (2005) 615-617
7. Fukumura D., Xu L., Chen Y., Gohongi T., Seed B., and Jain R.K. Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo. Cancer Res. 61 (2001) 6020-6024
8. Hui A.S., Bauer A.L., Striet J.B., Schnell P.O., and Czyzyk-Krzeska M.F. Calcium signaling stimulates translation of HIF-alpha during hypoxia. FASEB J. 20 (2006) 466-475
9. Jia Y., Zhou J., Tai Y., and Wang Y. TRPC channels promote cerebellar granule neuron survival. Nat. Neurosci. 10 (2007) 559-567
10. Kaur B., Khwaja F.W., Severson E.A., Matheny S.L., Brat D.J., and Van Meir E.G. Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis. Neuro-oncol. 7 (2005) 134-153
11. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25 (2001) 402-408
12. Meng F., To W.K., and Gu Y. Role of TRP channels and NCX in mediating hypoxia-induced [Ca(2+)](i) elevation in PC12 cells. Respir. Physiol. Neurobiol. 164 (2008) 386-393
13. Millhorn D.E., Beitner-Johnson D., Conforti L., Conrad P.W., Kobayashi S., Yuan Y., and Rust R. Gene regulation during hypoxia in excitable oxygen-sensing cells: depolarization-transcription coupling. Adv. Exp. Med. Biol. 475 (2000) 131-142
14. Moran M.M., Xu H., and Clapham D.E. TRP ion channels in the nervous system. Curr. Opin. Neurobiol. 14 (2004) 362-369
15. Mori Y., Wakamori M., Miyakawa T., Hermosura M., Hara Y., Nishida M., Hirose K., Mizushima A., Kurosaki M., Mori E., Gotoh K., Okada T., Fleig A., Penner R., Iino M., and Kurosaki T. Transient receptor potential 1 regulates capacitative Ca(2+) entry and Ca(2+) release from endoplasmic reticulum in B lymphocytes. J. Exp. Med. 195 (2002) 673-681
16. Pena F., and Ordaz B. Non-selective cation channel blockers: potential use in nervous system basic research and therapeutics. Mini Rev. Med. Chem. 8 (2008) 812-819
17. Pouyssegur J., Dayan F., and Mazure N.M. Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 441 (2006) 437-443
18. Rong Y., Durden D.L., Van Meir E.G., and Brat D.J. 'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis. J. Neuropathol. Exp. Neurol. 65 (2006) 529-539
19. Salnikow K., Kluz T., Costa M., Piquemal D., Demidenko Z.N., Xie K., and Blagosklonny M.V. The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia. Mol. Cell. Biol. 22 (2002) 1734-1741
20. 2+ signaling in cultured rat astrocytes. Glia 49 (2005) 153-157
21. 2+ in pulmonary arterial smooth muscle cells. Circ. Res. 98 (2006) 1528-1537
22. West A.E., Chen W.G., Dalva M.B., Dolmetsch R.E., Kornhauser J.M., Shaywitz A.J., Takasu M.A., Tao X., and Greenberg M.E. Calcium regulation of neuronal gene expression. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 11024-11031
23. Woods S.A., McGlade C.J., and Guha A. Phosphatidylinositol 3′-kinase and MAPK/ERK kinase 1/2 differentially regulate expression of vascular endothelial growth factor in human malignant astrocytoma cells. Neuro-oncol. 4 (2002) 242-252
24. 2+ exchanger. Biochim. Biophys. Acta 1593 (2003) 269-276
25. 2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia. J. Biol. Chem. 280 (2005) 4321-4328
26. Zygalaki E., Stathopoulou A., Kroupis C., Kaklamanis L., Kyriakides Z., Kremastinos D., and Lianidou E.S. Real-time reverse transcription-PCR quantification of vascular endothelial growth factor splice variants. Clin. Chem. 51 (2005) 1518-1520