Activity-based protein profiling reveals broad reactivity of the nerve agent sarin

Chemical Research in Toxicology

Volumn 22, Issue 4, 2009, Pages 683-689

  Tuin, Adriaan W ^a   Mol, Marijke A E ^b   Van Den Berg, Roland M ^b   Fidder, A ^b   Van Der Marel, Gijs A ^a   Overkleeft, Herman S ^a   Noort, Daan ^b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b TNO   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ACYLAMINO ACID RELEASING ENZYME; CARBOXYLESTERASE; DIPEPTIDYL PEPTIDASE; DIPEPTIDYL PEPTIDASE 9; FATTY ACID SYNTHASE; METHYLPHOSPHONOFLUORIDIC ACID; ORGANOPHOSPHATE; PALMITOYL COENZYME A HYDROLASE; PROLYL ENDOPEPTIDASE; SARIN; UNCLASSIFIED DRUG; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; HYDROLASE; NERVE GAS;

ANIMAL CELL; ARTICLE; BIOTINYLATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PROTEIN ANALYSIS; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; CHEMISTRY; LIVER; METABOLISM; RHESUS MONKEY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL CULTURE;

MACACA MULATTA;

ANIMALS; BUTYRYLCHOLINESTERASE; CHOLINESTERASE INHIBITORS; HUMANS; HYDROLASES; LIVER; MACACA MULATTA; MOLECULAR STRUCTURE; NERVE AGENTS; SARIN; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 66049096147     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx8004218     Document Type: Article

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