Human, but not bovine, photoreceptor outer segments prime human retinal pigment epithelial cells for metabolic activation and massive oxidant release in response to lipopolysaccharide and interferon-γ

Experimental Eye Research

Volumn 79, Issue 3, 2004, Pages 431-435

  Kindzelskii, Andrei L ^a   Elner, Victor M ^a   Elner, Susan G ^a   Yang, Dongli ^a   Hughes, Bret A ^a   Petty, Howard R ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

outer segments; oxidants; pro inflammatory conditions; RPE activation

Indexed keywords

GAMMA INTERFERON; LIPOPOLYSACCHARIDE; OXIDIZING AGENT; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CATTLE; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATION; METABOLIC ACTIVATION; NONHUMAN; OXIDATIVE STRESS; PHOTORECEPTOR MEMBRANE; PIGMENT EPITHELIUM; PRIORITY JOURNAL; SPECIES DIFFERENCE;

ANIMALS; CATTLE; CELLS, CULTURED; HUMANS; INTERFERON TYPE II; LIPOPOLYSACCHARIDES; OXIDANTS; PIGMENT EPITHELIUM OF EYE; REACTIVE OXYGEN SPECIES; ROD OUTER SEGMENTS;

EID: 4444257018     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2004.06.005     Document Type: Article

References (27)

1. Adachi Y., Kindzelskii A.L., Ohno N., Yadomae T., Petty H.R. Amplitude and frequency modulation of metabolic signals in leukocytes: synergistic role in interferon-γ and interleukin-6-mediated cell activation. J. Immunol. 163:1999;4367-4374
2. Beatty S., Koh H.-H., Henson D., Boulton M. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Sur. Ophthalmol. 45:2000;115-134
3. Cai J., Nelson K.C., Wu M., Sternberg P., Jones D.P. Oxidative damage and protection of the RPE. Prog. Retinal Eye Res. 19:2000;205-221
4. Chanock S.J., El Benna J., Chanock S.J., Smith R.M., Babior B.M. The respiratory burst oxidase. J. Biol. Chem. 269:1994;24519-24522
5. Dorey C.K., Khouri G.G., Syniuta L.A., Curran S.A., Weiter J.J. Superoxide production by porcine retinal pigment epithelium in vitro. Invest. Ophthalmol. Vis. Sci. 30:1989;1047-1054
6. Elner V.M., Streiter R.M., Elner V.M., Rollins B.J., Del Monte M.A., Kunkel S.L. Monocyte chemotactic protein gene expression by cytokine-treated human retinal pigment epithelial cells. Lab. Invest. 64:1991;819-825
7. Elner V.M., Elner S.G., Bian Z.M., Kindezelskii A.L., Yoshida A., Petty H.R. RPE CD14 immunohistochemical, genetic, and functional expression. Exp. Eye Res. 76:2003;321-331
8. Elner V.M., Burnstine M.A., Strieter R.M., Kunkel S.L., Elner S.G. Cell-associated human retinal pigment epithelium interleukin-8 and monocyte chemotactic protein-1: immunochemical and in-situ hybridization analyses. Exp. Eye Res. 65:1997;781-789
9. Hollborn M., Kohen L., Wiedemann P., Enzmann V. The influence of pro-inflammatory cytokines on human retinal pigment epithelium cell receptors. Graefes Arch. Clin. Exp. Ophthalmol. 239:2001;294-301
10. Laskowski I., Pratschke J., Wilhelm M.J., Gasser M., Tilney N.L. Molecular and cellular events associated with ischemia/reperfusion injury. Ann. Transplant. 5:2000;29-35
11. Lefer D.J., Granger D.N. Oxidative stress and cardiac disease. Am. J. Med. 109:2000;315-323
12. Li C., Jackson R.M. Reactive species mechanisms of cellular hypoxia-reoxygenation injury. Am. J. Physiol. Cell Physiol. 282:2002;C227-C241
13. Kindzelskii A.L., Petty H.R. Apparent role of traveling metabolic waves in periodic oxidant release by living cells. Proc. Natl Acad. Sci., USA. 99:2002;9207-9212
14. Kindzelskii A.L., Zhou M.-J., Haugland R.P., Boxer L.A., Petty H.R. Oscillatory pericellular proteolysis and oxidant deposition during neutrophil locomotion. Biophys. J. 74:1998;90-97
15. Kindzelskii A.L., Huang J.B., Chaiworapongsa T., Fahmy R.M., Kim Y.M., Romero R., Petty H.R. Pregnancy alters glucose-6-phosphate dehydrogenase trafficking, cell metabolism, and oxidant release of maternal neutrophils. J. Clin. Invest. 110:2002;1801-1811
16. McLaren M.J., Inana G., Li C.Y. Double fluorescent vital assay of phagocytosis by cultured retinal pigment epithelial cells. Invest. Opthalmol. Vis. Sci. 34:1993;317-326
17. Miceli M.V., Newsome D.A., Schriver G.W. Glucose uptake, hexose monophosphate shunt activity, and oxygen consumption in cultured human retinal pigment epithelial cells. Invest. Opthalmol. Vis. Sci. 31:1990;277-283
18. Miceli M.V., Liles M.R., Newsome D.A. Evaluation of oxidative processes in human pigment epithelial cells associated with retinal outer segment phagocytosis. Exp. Cell Res. 214:1994;242-249
19. Olsen L.F., Kummer U., Kindzelskii A.L., Petty H.R. A model of the oscillatory metabolism of activated neutrophils. Biophys. J. 84:2003;69-81
20. Ophir A., Chevion M. A possible role of free radicals in the transplantation of retinal pigment epithelial cells. Ophthalmic. Surg. 23:1992;284-287
21. Petty H.R. Neutrophil oscillations: temporal and spatiotemporal aspects of cell behavior. Immunol. Res. 23:2001;85-94
22. Rao N.A. Role of oxygen free radicals in retinal damage associated with experimental uveitis. Trans. Am. Ophthalmol. Soc. 88:1990;797-850
23. Rosenbaum J.T., McDevitt H.O., Guss R.B., Egbert P.R. Endotoxin-induced uveitis in rats as a model for human disease. Nature. 286:1980;611-613
24. Tate D.J. Jr, Miceli M.V., Newsome D.A. Phagocytosis and H2O2 induce catalase and metallothionein gene expression in human retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 36:1995;1271-1279
25. Truscott R.J. Age-related nuclear cataract: a lens transport problem. Ophthalmic Res. 32:2000;185-194
26. Winkler B.S., Boulton M.E., Gottsch J.D., Sternberg P. Oxidative damage and age-related macular degeneration. Mol. Vis. 5:1999;32-42
27. Wu G.S., Rao N.A. Activation of NADPH oxidase by docosahexaenoic acid hydroperoxide and its inhibition by a novel retinal pigment epithelial protein. Invest. Ophthalmol. Vis. Sci. 40:1999;831-839