Edaravone (MCI-186), a free radical scavenger, attenuates retinal ischemia/reperfusion injury in rats

Acta Pharmacologica Sinica

Volumn 29, Issue 7, 2008, Pages 823-828

  Song, Yi ^a   Gong, Yuan Yuan ^a   Xie, Zheng Gao ^a   Li, Cai Hong ^a   Gu, Qing ^a   Wu, Xing Wei ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Apoptosis; Edaravone; Free radical scavenger; Ischemia reperfusion injury; Oxidative stress; Retina

Indexed keywords

MALONALDEHYDE; NORPHENAZONE; SCAVENGER; SUPEROXIDE DISMUTASE; DRUG DERIVATIVE; PHENAZONE; PHENYLMETHYLPYRAZOLONE;

A WAVE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; B WAVE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ELECTRORETINOGRAM; ENZYME ACTIVITY; EYE PROTECTION; MALE; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; RAT; REPERFUSION INJURY; RETINA ISCHEMIA; RETINA NERVE CELL; TISSUE LEVEL; ANIMAL; ELECTRORETINOGRAPHY; METABOLISM; PATHOLOGY; RETINA DISEASE; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIPYRINE; APOPTOSIS; ELECTRORETINOGRAPHY; FREE RADICAL SCAVENGERS; IN SITU NICK-END LABELING; MALE; MALONDIALDEHYDE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; RETINAL DISEASES; SUPEROXIDE DISMUTASE;

EID: 65849305886     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2008.00822.x     Document Type: Article

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