Structure of nicotinamide mononucleotide adenylyltransferase: A key enzyme in NAD+ biosynthesis

Structure

Volumn 8, Issue 9, 2000, Pages 993-1004

  D'Angelo, Igor ^a   Raffaelli, Nadia ^b   Dabusti, Valerio ^a   Lorenzi, Teresa ^b   Magni, Giulio ^b   Rizzi, Menico ^a,c  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^c UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

Catalysis; Enzyme structure; NAD biosynthesis; NMN adenylyltransferase; Nucleotidyltransferase family

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE NUCLEOTIDE ADENYLYLTRANSFERASE; PANTETHEINE PHOSPHATE;

ARTICLE; CELL METABOLISM; ENZYME STRUCTURE; METHANOCOCCUS JANNASCHII; NONHUMAN; NUCLEOTIDE METABOLISM; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FOLDING; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS;

METHANOCALDOCOCCUS JANNASCHII; METHANOCOCCUS; METHANOCOCCUS JANNASCHII;

EID: 0034665459     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(00)00190-8     Document Type: Article

References (51)

1. NAD biosynthesis and recycling
2. + biosynthesis
3. The stereochemical course of nucleotydyl transfer catalysed by NAD pyrophosphorylase
4. Nuclear matrix-associated NMN adenylyltransferase activity in human placenta
5. Evidence of an inhibitory effect exerted by yeast NMN adenylyltransferase on poly(ADP-ribose) polymerase activity
6. The antitumor drug, 1,'-bis-(2-chloroethyl)-1-nitrosourea, inactivates human nicotinamide mononucleotide adenylyltransferase
7. Mechanism of resistance to tiazofurin in hepatoma 3924A
8. Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis
9. Aminoacyl-tRNA synthetase
10. Molecular uniformity in biological catalyses. The enzymes concerned with firefly luciferin, amino acid, and fatty acid utilization are compared
11. Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzyme
12. Site-selected mutagenesis of a conserved nucleotide binding HXGH motif located in the ATP sulfurylase domain of human bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase
13. 'ADP sulfurylase' from Thiobacillus denitrificans is an adenylylsulfate: Phosphate adenylyltransferase and belongs to a new family of nucleotidyltransferases
14. The crystal structure of a novel bacterial adenylyltransferase reveals half of sites reactivity
15. A prototypical cytydyltransferase: CTP:glycerol-3-phosphate cytydyltransferase from Bacillus subtilis
16. The cytydyltransferase superfamily: Identification of the nucleotide-binding site and fold prediction
17. + synthetase from Bacillus subtilis
18. A new function for a common fold: The crystal structure of quinolinic acid phosphoribosyltransferase
19. Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: A potent TB drug target
20. Structure of L-aspartate oxidase: Implications for the succinate dehydrogenase/fumarate reductase oxidoreductase family
21. PROCHECK: A program to check the stereochemistry of protein structures
22. Evolutionary and structure relationships among dehydrogenases
23. The CCP4 suite: Programs for protein crystallography
24. The α-helix dipole and the properties of proteins
25. Aromatic-aromatic interaction: A mechanism of protein structure stabilisation
26. Cation-pi interactions in structural biology
27. Structural basis for transfer RNA aminoacylation by Escherichia coli glutamyl-tRNA synthetase
28. Comparison of the Coordinative behavior of calcium (II) and magnesium (II) from crystallographic data
29. Structural basis of anticodon loop recognition by glutaminyl-tRNA synthetase
30. Protein structure comparison by alignment of distance matrices
31. Purification and characterisation of phosphopantetheine adenylyltransferase from Escherichia coli
32. Characterization of nicotinamide mononucleotide adenylyltransferase from Thermophilic archea
33. Identification of the archaeal NMN adenylytransferase gene
34. Dissection of the structure and activity of the tyrosyl-tRNA synthetase by site-directed mutagenesis
35. A novel deamido-NAD-binding site revealed by the trapped NAD-adenylate intermediate in NAD synthetase structure
36. Solvent content of protein crystals
37. Heavy atom location using SHELXS-90
38. Maximum likelihood refinement of heavy atom parameters
39. AMoRe: An automated procedure for molecular replacement
40. The detections of subunits within the crystallographic asymmetric unit
41. The locked rotation function
42. Not your average density
43. Phase combination and cross validation in iterated density-modification calculations
44. Improved methods for building models in electron density maps and the location of errors in these models
45. Refinement of macromolecular structures by the maximum-likelihood method
46. The free R value: A novel statistical quantity for assessing the accuracy of crystal structures
47. Automated refinement of protein models
48. CLUSTAL: A package for performing multiple sequence alignment on a microcomputer
49. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
50. GRASP: Graphical representation and analysis of surface properties