Gsα deficiency in skeletal muscle leads to reduced muscle mass, fiber-type switching, and glucose intolerance without insulin resistance or deficiency

American Journal of Physiology - Cell Physiology

Volumn 296, Issue 4, 2009, Pages

  Chen, Min ^a   Feng, Han Zhong ^b   Gupta, Divakar ^a,c   Kelleher, James ^a,f   Dickerson, Kathryn E ^a,d   Wang, Jie ^a   Hunt, Desmond ^a,e   Jou, William ^a   Gavrilova, Oksana ^a   Jin, Jian Ping ^b   Weinstein, Lee S ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNITED STATES PHARMACOPEIA   (United States)

^f RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Atrophy; G protein

Indexed keywords

CREATINE KINASE MM; CYCLIC AMP; FATTY ACID; GLUCOSE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MYOSIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; BODY WEIGHT; CONTROLLED STUDY; ENERGY METABOLISM; FATTY ACID BLOOD LEVEL; FORCE; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HEAVY CHAIN; INSULIN BLOOD LEVEL; INSULIN DEFICIENCY; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; KINETICS; KNOCKOUT MOUSE; MALE; METABOLISM; MITOCHONDRION; MOUSE; MUSCLE CELL; MUSCLE FUNCTION; MUSCLE MASS; NONHUMAN; OXIDATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TRANSGENIC MOUSE; TRIACYLGLYCEROL BLOOD LEVEL;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BLOOD GLUCOSE; ENERGY METABOLISM; FATTY ACIDS; FEMALE; GLUCOSE INTOLERANCE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; INSULIN; INSULIN RESISTANCE; MALE; MICE; MICE, KNOCKOUT; MUSCLE CONTRACTION; MUSCLE FIBERS, FAST-TWITCH; MUSCLE FIBERS, SLOW-TWITCH; MUSCLE STRENGTH; MUSCLE, SKELETAL; MUSCULAR ATROPHY; MYOSIN HEAVY CHAINS; OXIDATION-REDUCTION; SIGNAL TRANSDUCTION; TIME FACTORS; TRANS-ACTIVATORS;

MUS; MUS MUSCULUS;

EID: 65649096620     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00443.2008     Document Type: Article

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