메뉴 건너뛰기




Volumn 4, Issue 4, 2008, Pages 259-268

Emerging role for antioxidant therapy in protection against diabetic cardiac complications: Experimental and clinical evidence for utilization of classic and new antioxidants

Author keywords

Antioxidants; Diabetes mellitus; Diabetic cardiomyopathy; Heart failure; Myocardial infarction; Oxidative stress

Indexed keywords

3,4 DIHYDRO 4,4 DIMETHYL 1,3 BENZOSELENAZINE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CARDIOVASCULAR AGENT; GLUTATHIONE; METALLOTHIONEIN; PLACEBO; POLYUNSATURATED FATTY ACID; REACTIVE OXYGEN METABOLITE; RESVERATROL; TEMPOL; UNCLASSIFIED DRUG; ZINC;

EID: 65649090962     PISSN: 1573403X     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340308786349453     Document Type: Review
Times cited : (39)

References (112)
  • 1
    • 0043025552 scopus 로고    scopus 로고
    • Heart failure: The frequent, forgotten, and often fatal complication of diabetes
    • Bell DS. Heart failure: the frequent, forgotten, and often fatal complication of diabetes. Diabetes Care 2003; 26: 2433-41.
    • (2003) Diabetes Care , vol.26 , pp. 2433-2441
    • Bell, D.S.1
  • 2
    • 0034844049 scopus 로고    scopus 로고
    • Mortality and causes of death in the WHO Multinational Study of Vascular Disease in Diabetes
    • Morrish NJ, Wang SL, Stevens LK, Fuller JH, Keen H. Mortality and causes of death in the WHO Multinational Study of Vascular Disease in Diabetes. Diabetologia 2001; 44 (Suppl 2): S14-21.
    • (2001) Diabetologia , vol.44 , Issue.SUPPL. 2
    • Morrish, N.J.1    Wang, S.L.2    Stevens, L.K.3    Fuller, J.H.4    Keen, H.5
  • 3
    • 0030462332 scopus 로고    scopus 로고
    • Angiographic findings and outcome in diabetic patients treated with thrombolytic therapy for acute myocardial infarction: The GUSTO-I experience
    • Woodfield SL, Lundergan CF, Reiner JS, et al. Angiographic findings and outcome in diabetic patients treated with thrombolytic therapy for acute myocardial infarction: the GUSTO-I experience. J Am Coll Cardiol 1996; 28: 1661-9.
    • (1996) J Am Coll Cardiol , vol.28 , pp. 1661-1669
    • Woodfield, S.L.1    Lundergan, C.F.2    Reiner, J.S.3
  • 4
    • 0035432974 scopus 로고    scopus 로고
    • Impact of diabetes on long-term survival after acute myocardial infarction: Comparability of risk with prior myocardial infarction
    • Mukamal KJ, Nesto RW, Cohen MC, et al. Impact of diabetes on long-term survival after acute myocardial infarction: comparability of risk with prior myocardial infarction. Diabetes Care 2001; 24: 1422-7.
    • (2001) Diabetes Care , vol.24 , pp. 1422-1427
    • Mukamal, K.J.1    Nesto, R.W.2    Cohen, M.C.3
  • 5
    • 0021139777 scopus 로고
    • Increased congestive heart failure after myocardial infarction of modest extent in patients with diabetes mellitus
    • Jaffe AS, Spadaro JJ, Schechtman K, Roberts R, Geltman EM, Sobel BE. Increased congestive heart failure after myocardial infarction of modest extent in patients with diabetes mellitus. Am Heart J 1984; 108: 31-7.
    • (1984) Am Heart J , vol.108 , pp. 31-37
    • Jaffe, A.S.1    Spadaro, J.J.2    Schechtman, K.3    Roberts, R.4    Geltman, E.M.5    Sobel, B.E.6
  • 6
    • 0037015256 scopus 로고    scopus 로고
    • Survival And Ventricular Enlargement (SAVE) Investigators. Ventricular remodeling does not accompany the development of heart failure in diabetic patients after myocardial infarction
    • Solomon SD, St John Sutton M, Lamas GA, et al. Survival And Ventricular Enlargement (SAVE) Investigators. Ventricular remodeling does not accompany the development of heart failure in diabetic patients after myocardial infarction. Circulation 2002; 106: 1251-5.
    • (2002) Circulation , vol.106 , pp. 1251-1255
    • Solomon, S.D.1    St John Sutton, M.2    Lamas, G.A.3
  • 7
    • 0029945389 scopus 로고    scopus 로고
    • Clinical characteristics, left and right ventricular ejection fraction, and long-term prognosis in patients with non-insulin-dependent diabetes surviving an acute myocardial infarction
    • Melchior T, Gadsboll N, Hildebrandt P, Kober L, Torp-Pedersen C. Clinical characteristics, left and right ventricular ejection fraction, and long-term prognosis in patients with non-insulin-dependent diabetes surviving an acute myocardial infarction. Diabet Med 1996; 13: 450-6.
    • (1996) Diabet Med , vol.13 , pp. 450-456
    • Melchior, T.1    Gadsboll, N.2    Hildebrandt, P.3    Kober, L.4    Torp-Pedersen, C.5
  • 8
    • 0031051579 scopus 로고    scopus 로고
    • Mechanisms determining course and outcome of diabetic patients who have had acute myocardial infarction
    • Aronson D, Rayfield EJ, Chesebro JH. Mechanisms determining course and outcome of diabetic patients who have had acute myocardial infarction. Ann Intern Med 1997; 126: 296-306.
    • (1997) Ann Intern Med , vol.126 , pp. 296-306
    • Aronson, D.1    Rayfield, E.J.2    Chesebro, J.H.3
  • 9
    • 0031091973 scopus 로고    scopus 로고
    • Ten-year survival after acute myocardial infarction: Comparison of patients with and without diabetes. SPRINT Study Group. Secondary Prevention Reinfarction Israeli Nifedipine Trial
    • Behar S, Boyko V, Reicher-Reiss H, Goldbourt U. Ten-year survival after acute myocardial infarction: comparison of patients with and without diabetes. SPRINT Study Group. Secondary Prevention Reinfarction Israeli Nifedipine Trial. Am Heart J 1997; 133: 290-6.
    • (1997) Am Heart J , vol.133 , pp. 290-296
    • Behar, S.1    Boyko, V.2    Reicher-Reiss, H.3    Goldbourt, U.4
  • 10
    • 33644548673 scopus 로고    scopus 로고
    • Diabetic heart disease
    • Marwick TH. Diabetic heart disease. Heart 2006; 92: 296-300.
    • (2006) Heart , vol.92 , pp. 296-300
    • Marwick, T.H.1
  • 11
    • 36649036593 scopus 로고    scopus 로고
    • Heart failure in diabetes and related conditions
    • Kamalesh M. Heart failure in diabetes and related conditions. J Card Fail 2007; 13: 861-73.
    • (2007) J Card Fail , vol.13 , pp. 861-873
    • Kamalesh, M.1
  • 12
    • 0031752685 scopus 로고    scopus 로고
    • Global burden of diabetes, 1995-2025: Prevalence, numerical estimates, and projections
    • King H, Aubert RE, Herman WH. Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care 1998; 21: 1414-31.
    • (1998) Diabetes Care , vol.21 , pp. 1414-1431
    • King, H.1    Aubert, R.E.2    Herman, W.H.3
  • 14
    • 0031871066 scopus 로고    scopus 로고
    • Altered activities of transcription factors and their related gene expression in cardiac tissues of diabetic rats
    • Nishio Y, Kashiwagi A, Taki H, et al. Altered activities of transcription factors and their related gene expression in cardiac tissues of diabetic rats. Diabetes 1998; 47: 1318-25.
    • (1998) Diabetes , vol.47 , pp. 1318-1325
    • Nishio, Y.1    Kashiwagi, A.2    Taki, H.3
  • 16
    • 0035749812 scopus 로고    scopus 로고
    • Oxidative stress and diabetic cardiomyopathy: A brief review
    • Cai L, Kang YJ. Oxidative stress and diabetic cardiomyopathy: a brief review. Cardiovasc Toxicol 2001; 1: 181-93.
    • (2001) Cardiovasc Toxicol , vol.1 , pp. 181-193
    • Cai, L.1    Kang, Y.J.2
  • 17
    • 85026134580 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular disease in type 2 diabetes: The role of antioxidants and pro-oxidants
    • Penckofer S, Schwertz D, Florczak K. Oxidative stress and cardiovascular disease in type 2 diabetes: the role of antioxidants and pro-oxidants. J Cardiovasc Nurs 2002; 6: 68-85.
    • (2002) J Cardiovasc Nurs , vol.6 , pp. 68-85
    • Penckofer, S.1    Schwertz, D.2    Florczak, K.3
  • 18
    • 0036481698 scopus 로고    scopus 로고
    • Early increase of oxidative stress and reduced antioxidant defenses in patients with uncomplicated type 1 diabetes: A case for gender difference
    • Marra G, Cotroneo P, Pitocco D, et al. Early increase of oxidative stress and reduced antioxidant defenses in patients with uncomplicated type 1 diabetes: a case for gender difference. Diabetes Care 2002; 25: 370-5.
    • (2002) Diabetes Care , vol.25 , pp. 370-375
    • Marra, G.1    Cotroneo, P.2    Pitocco, D.3
  • 19
    • 0034619027 scopus 로고    scopus 로고
    • Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): Randomised placebo-controlled trial
    • Boaz M, Smetana S, Weinstein T, et al. Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo-controlled trial. Lancet 2000; 356: 1213-8.
    • (2000) Lancet , vol.356 , pp. 1213-1218
    • Boaz, M.1    Smetana, S.2    Weinstein, T.3
  • 20
    • 0029925181 scopus 로고    scopus 로고
    • Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)
    • Stephens NG, Parsons A, Schofield PM, Kelly F, Cheeseman K, Mitchinson MJ. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS) Lancet 1996; 347: 781-6.
    • (1996) Lancet , vol.347 , pp. 781-786
    • Stephens, N.G.1    Parsons, A.2    Schofield, P.M.3    Kelly, F.4    Cheeseman, K.5    Mitchinson, M.J.6
  • 21
    • 0030052161 scopus 로고    scopus 로고
    • Usefulness of antioxidant vitamins in suspected acute myocardial infarction (the Indian experiment of infarct survival-3)
    • Singh RB, Niaz MA, Rastogi SS, Rastogi S. Usefulness of antioxidant vitamins in suspected acute myocardial infarction (the Indian experiment of infarct survival-3) Am J Cardiol 1996; 77: 232-6.
    • (1996) Am J Cardiol , vol.77 , pp. 232-236
    • Singh, R.B.1    Niaz, M.A.2    Rastogi, S.S.3    Rastogi, S.4
  • 22
    • 0345109256 scopus 로고    scopus 로고
    • Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: Results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico
    • Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet 1999; 354: 447-55.
    • (1999) Lancet , vol.354 , pp. 447-455
  • 23
    • 0034688195 scopus 로고    scopus 로고
    • Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
    • Yusuf S, Dagenais G, Pogue J, Bosch J, Sleight P. Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000; 342: 154-60.
    • (2000) N Engl J Med , vol.342 , pp. 154-160
    • Yusuf, S.1    Dagenais, G.2    Pogue, J.3    Bosch, J.4    Sleight, P.5
  • 24
    • 21444438990 scopus 로고    scopus 로고
    • Vitamin E in the primary prevention of cardiovascular disease and cancer: The Women's Health Study: a randomized controlled trial
    • Lee IM, Cook NR, Gaziano JM, et al. Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trial. JAMA 2005; 294: 56-65.
    • (2005) JAMA , vol.294 , pp. 56-65
    • Lee, I.M.1    Cook, N.R.2    Gaziano, J.M.3
  • 25
    • 0033735493 scopus 로고    scopus 로고
    • Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) study: A randomized trial of the effect of vitamins E and C on 3-year progression of carotid atherosclerosis
    • Salonen JT, Nyyssonen K, Salonen R, et al. Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) study: a randomized trial of the effect of vitamins E and C on 3-year progression of carotid atherosclerosis. J Intern Med 2000; 248: 377-86.
    • (2000) J Intern Med , vol.248 , pp. 377-386
    • Salonen, J.T.1    Nyyssonen, K.2    Salonen, R.3
  • 26
    • 0037126049 scopus 로고    scopus 로고
    • VEAPS Research Group. VEAPS Research Group: Alpha-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis: the Vitamin E Atherosclerosis Prevention Study (VEAPS)
    • Hodis HN, Mack WJ, LaBree L, et al. VEAPS Research Group. VEAPS Research Group: Alpha-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis: the Vitamin E Atherosclerosis Prevention Study (VEAPS). Circulation 2002; 106: 1453-9.
    • (2002) Circulation , vol.106 , pp. 1453-1459
    • Hodis, H.N.1    Mack, W.J.2    LaBree, L.3
  • 29
    • 0025214625 scopus 로고
    • A relative deficit in antioxidant reserve may contribute in cardiac failure
    • Singal PK, Kirshenbaum LA. A relative deficit in antioxidant reserve may contribute in cardiac failure. Can J Cardiol 1990; 6: 47-9.
    • (1990) Can J Cardiol , vol.6 , pp. 47-49
    • Singal, P.K.1    Kirshenbaum, L.A.2
  • 30
    • 0022464782 scopus 로고
    • Oxygen, ischemia and inflammation
    • Weiss SJ. Oxygen, ischemia and inflammation. Acta Physiol Scand Suppl 1986; 548: 9-37.
    • (1986) Acta Physiol Scand Suppl , vol.548 , pp. 9-37
    • Weiss, S.J.1
  • 31
    • 0018240723 scopus 로고
    • Species, tissue and subcellular distribution of non Se-dependent glutathione peroxidase activity
    • Lawrence RA, Burk RF. Species, tissue and subcellular distribution of non Se-dependent glutathione peroxidase activity. J Nutr 1978; 108: 211-5.
    • (1978) J Nutr , vol.108 , pp. 211-215
    • Lawrence, R.A.1    Burk, R.F.2
  • 32
    • 0002668696 scopus 로고
    • Vitamin E is nature's master antioxidant
    • Packer L. Vitamin E is nature's master antioxidant. Sci Am Sci Med 1994; 54-63.
    • (1994) Sci Am Sci Med , pp. 54-63
    • Packer, L.1
  • 33
    • 0020668901 scopus 로고
    • Potential oxidative pathways of catecholamines in the formation of lipid peroxides and genesis of heart disease
    • Singal PK, Beamish RE, Dhalla NS. Potential oxidative pathways of catecholamines in the formation of lipid peroxides and genesis of heart disease. Adv Exp Med Biol 1983; 161: 391-401.
    • (1983) Adv Exp Med Biol , vol.161 , pp. 391-401
    • Singal, P.K.1    Beamish, R.E.2    Dhalla, N.S.3
  • 34
    • 0024261046 scopus 로고
    • Vitamin E deficiency accentuates adriamycin-induced cardiomyopathy and cell surface changes
    • Singal PK, Tong JG. Vitamin E deficiency accentuates adriamycin-induced cardiomyopathy and cell surface changes. Mol Cell Biochem 1988; 84: 163-71.
    • (1988) Mol Cell Biochem , vol.84 , pp. 163-171
    • Singal, P.K.1    Tong, J.G.2
  • 35
    • 0025317268 scopus 로고
    • Glutathione: Toxicological implications
    • Reed DJ. Glutathione: toxicological implications. Annu Rev Pharmacol Toxicol 1990; 30: 603-31.
    • (1990) Annu Rev Pharmacol Toxicol , vol.30 , pp. 603-631
    • Reed, D.J.1
  • 36
    • 0022967418 scopus 로고
    • Oxygen free radicals and reperfusion injury; the effect of ischaemia and reperfusion on the cellular ability to neutralise oxygen toxicity
    • Ferrari R, Ceconi C, Curello S, Cargnoni A, Medici D. Oxygen free radicals and reperfusion injury; the effect of ischaemia and reperfusion on the cellular ability to neutralise oxygen toxicity. J Mol Cell Cardiol 1986; 18 (Suppl 4): 67-9.
    • (1986) J Mol Cell Cardiol , vol.18 , Issue.SUPPL. 4 , pp. 67-69
    • Ferrari, R.1    Ceconi, C.2    Curello, S.3    Cargnoni, A.4    Medici, D.5
  • 38
    • 0024892114 scopus 로고
    • Time course of structure, function, and metabolic changes due to an exogenous source of oxygen metabolites in rat heart
    • Gupta M, Singal PK. Time course of structure, function, and metabolic changes due to an exogenous source of oxygen metabolites in rat heart. Can J Physiol Pharmacol 1989; 67: 1549-59.
    • (1989) Can J Physiol Pharmacol , vol.67 , pp. 1549-1559
    • Gupta, M.1    Singal, P.K.2
  • 39
    • 0032211569 scopus 로고    scopus 로고
    • Subcellular remodeling and heart dysfunction in chronic diabetes
    • Dhalla NS, Liu X, Panagia V, Takeda N. Subcellular remodeling and heart dysfunction in chronic diabetes. Cardiovasc Res 1998; 40: 239-47.
    • (1998) Cardiovasc Res , vol.40 , pp. 239-247
    • Dhalla, N.S.1    Liu, X.2    Panagia, V.3    Takeda, N.4
  • 41
    • 0023259759 scopus 로고
    • Glucose autoxidation and protein modification. The potential role of 'autoxidative glycosylation' in diabetes
    • Wolff SP, Dean RT. Glucose autoxidation and protein modification. The potential role of 'autoxidative glycosylation' in diabetes. Biochem J 1987; 245: 243-50.
    • (1987) Biochem J , vol.245 , pp. 243-250
    • Wolff, S.P.1    Dean, R.T.2
  • 42
    • 0025096104 scopus 로고
    • Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose
    • Hunt JV, Smith CC, Wolff SP. Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose. Diabetes 1990; 39: 1420-4.
    • (1990) Diabetes , vol.39 , pp. 1420-1424
    • Hunt, J.V.1    Smith, C.C.2    Wolff, S.P.3
  • 43
    • 0030009314 scopus 로고    scopus 로고
    • BCL-2 expression or antioxidants prevent hyperglycemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells
    • Giardino I, Edelstein D, Brownlee M. BCL-2 expression or antioxidants prevent hyperglycemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells. J Clin Invest 1996; 97:1422-8.
    • (1996) J Clin Invest , vol.97 , pp. 1422-1428
    • Giardino, I.1    Edelstein, D.2    Brownlee, M.3
  • 44
    • 0028873551 scopus 로고
    • Elevated lipid peroxidation and vitamin Equinone levels in heart ventricles of streptozotocin-treated diabetic rats
    • Jain SK, Levine SN. Elevated lipid peroxidation and vitamin Equinone levels in heart ventricles of streptozotocin-treated diabetic rats. Free Radic Biol Med 1995; 18: 337-41.
    • (1995) Free Radic Biol Med , vol.18 , pp. 337-341
    • Jain, S.K.1    Levine, S.N.2
  • 45
    • 0025369970 scopus 로고
    • The measurement and mechanism of lipid peroxidation in biological systems
    • Gutteridge JM, Halliwell B. The measurement and mechanism of lipid peroxidation in biological systems. Trends Biochem Sci 1990; 15: 129-35.
    • (1990) Trends Biochem Sci , vol.15 , pp. 129-135
    • Gutteridge, J.M.1    Halliwell, B.2
  • 46
    • 0028026637 scopus 로고
    • Assay of malondialdehyde in biological fluids by gas chromatography-mass spectrometry
    • Yeo HC, Helbock HJ, Chyu DW, Ames BN. Assay of malondialdehyde in biological fluids by gas chromatography-mass spectrometry. Anal Biochem 1994; 220: 391-6.
    • (1994) Anal Biochem , vol.220 , pp. 391-396
    • Yeo, H.C.1    Helbock, H.J.2    Chyu, D.W.3    Ames, B.N.4
  • 47
    • 33646932475 scopus 로고    scopus 로고
    • The generation and actions of isoprostanes
    • Roberts LJ 2nd, Morrow JD. The generation and actions of isoprostanes. Biochim Biophys Acta 1997; 1345: 121-35.
    • (1997) Biochim Biophys Acta , vol.1345 , pp. 121-135
    • Roberts 2nd, L.J.1    Morrow, J.D.2
  • 48
    • 0025572704 scopus 로고    scopus 로고
    • Morrow JD, Hill KE, Burk RF, Nammour TM, Badr KF, Roberts LJ 2nd. A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. Proc Natl Acad Sci USA 1990; 87: 9383-7.
    • Morrow JD, Hill KE, Burk RF, Nammour TM, Badr KF, Roberts LJ 2nd. A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. Proc Natl Acad Sci USA 1990; 87: 9383-7.
  • 49
    • 10044235066 scopus 로고    scopus 로고
    • Montuschi P, Barnes PJ, Roberts LJ 2nd. Isoprostanes: markers and mediators of oxidative stress. FASEB J 2004; 18: 1791-800.
    • Montuschi P, Barnes PJ, Roberts LJ 2nd. Isoprostanes: markers and mediators of oxidative stress. FASEB J 2004; 18: 1791-800.
  • 50
    • 0030610106 scopus 로고    scopus 로고
    • 8-epi PGF2 alpha generation during coronary reperfusion. A potential quantitative marker of oxidant stress in vivo
    • Delanty N, Reilly MP, Pratico D, et al. 8-epi PGF2 alpha generation during coronary reperfusion. A potential quantitative marker of oxidant stress in vivo. Circulation 1997; 95: 2492-9.
    • (1997) Circulation , vol.95 , pp. 2492-2499
    • Delanty, N.1    Reilly, M.P.2    Pratico, D.3
  • 51
    • 24944490072 scopus 로고    scopus 로고
    • Greater propensity of diabetic myocardium for oxidative stress after myocardial infarction is associated with the development of heart failure
    • Smith HM, Hamblin M, Hill MF. Greater propensity of diabetic myocardium for oxidative stress after myocardial infarction is associated with the development of heart failure. J Mol Cell Cardiol 2005; 39: 657-65.
    • (2005) J Mol Cell Cardiol , vol.39 , pp. 657-665
    • Smith, H.M.1    Hamblin, M.2    Hill, M.F.3
  • 52
    • 34047111193 scopus 로고    scopus 로고
    • Alterations in the diabetic myocardial proteome coupled with increased myocardial oxidative stress underlies diabetic cardiomyopathy
    • Hamblin M, Friedman DB, Hill S, Caprioli RM, Smith HM, Hill MF. Alterations in the diabetic myocardial proteome coupled with increased myocardial oxidative stress underlies diabetic cardiomyopathy. J Mol Cell Cardiol 2007; 42: 884-95.
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 884-895
    • Hamblin, M.1    Friedman, D.B.2    Hill, S.3    Caprioli, R.M.4    Smith, H.M.5    Hill, M.F.6
  • 53
    • 36649026948 scopus 로고    scopus 로고
    • Dietary supplementation with vitamin E ameliorates cardiac failure in type I diabetic cardiomyopathy by suppressing myocardial generation of 8-isoprostaglandin F2alpha and oxidized glutathione
    • Hamblin M, Smith HM, Hill MF. Dietary supplementation with vitamin E ameliorates cardiac failure in type I diabetic cardiomyopathy by suppressing myocardial generation of 8-isoprostaglandin F2alpha and oxidized glutathione. J Card Fail 2007; 13: 884-92.
    • (2007) J Card Fail , vol.13 , pp. 884-892
    • Hamblin, M.1    Smith, H.M.2    Hill, M.F.3
  • 54
    • 0030726212 scopus 로고    scopus 로고
    • Defective plasma antioxidant defenses and enhanced susceptibility to lipid peroxidation in uncomplicated IDDM
    • Santini SA, Marra G, Giardina B, et al. Defective plasma antioxidant defenses and enhanced susceptibility to lipid peroxidation in uncomplicated IDDM. Diabetes 1997; 46: 1853-8.
    • (1997) Diabetes , vol.46 , pp. 1853-1858
    • Santini, S.A.1    Marra, G.2    Giardina, B.3
  • 55
    • 0034645794 scopus 로고    scopus 로고
    • Comparison of oxidative stress indicators in plasma of recent-onset and long-term type 1 diabetic patients
    • Güzel S, Seven A, Satman I, Burçak G. Comparison of oxidative stress indicators in plasma of recent-onset and long-term type 1 diabetic patients. J Toxicol Environ Health A 2000; 59: 7-14.
    • (2000) J Toxicol Environ Health A , vol.59 , pp. 7-14
    • Güzel, S.1    Seven, A.2    Satman, I.3    Burçak, G.4
  • 57
    • 0019796887 scopus 로고
    • Lipid peroxide levels of serum lipoprotein fractions of diabetic patients
    • Nishigaki I, Hagihara M, Tsunekawa H, Maseki M, Yagi K. Lipid peroxide levels of serum lipoprotein fractions of diabetic patients. Biochem Med 1981; 25: 373-8.
    • (1981) Biochem Med , vol.25 , pp. 373-378
    • Nishigaki, I.1    Hagihara, M.2    Tsunekawa, H.3    Maseki, M.4    Yagi, K.5
  • 58
    • 0032905015 scopus 로고    scopus 로고
    • In vivo formation of 8-isoprostaglandin f2alpha and platelet activation in diabetes mellitus: Effects of improved metabolic control and vitamin E supplementation
    • Davì G, Ciabattoni G, Consoli A, et al. In vivo formation of 8-isoprostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation. Circulation 1999; 99: 224-9.
    • (1999) Circulation , vol.99 , pp. 224-229
    • Davì, G.1    Ciabattoni, G.2    Consoli, A.3
  • 61
    • 0030837996 scopus 로고    scopus 로고
    • High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells
    • Cosentino F, Hishikawa K, Katusic ZS, Lüscher TF. High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation 1997; 96: 25-8.
    • (1997) Circulation , vol.96 , pp. 25-28
    • Cosentino, F.1    Hishikawa, K.2    Katusic, Z.S.3    Lüscher, T.F.4
  • 62
    • 0026485192 scopus 로고
    • Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase
    • Ischiropoulos H, Zhu L, Chen J, et al. Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch Biochem Biophys 1992; 298: 431-7.
    • (1992) Arch Biochem Biophys , vol.298 , pp. 431-437
    • Ischiropoulos, H.1    Zhu, L.2    Chen, J.3
  • 63
    • 4344593331 scopus 로고    scopus 로고
    • Expression of angiogenic factors during acute coronary syndromes in human type 2 diabetes
    • Marfella R, Esposito K, Nappo F, et al. Expression of angiogenic factors during acute coronary syndromes in human type 2 diabetes. Diabetes 2004; 53: 2383-91.
    • (2004) Diabetes , vol.53 , pp. 2383-2391
    • Marfella, R.1    Esposito, K.2    Nappo, F.3
  • 64
    • 33747482292 scopus 로고    scopus 로고
    • Effect of moderate red wine intake on cardiac prognosis after recent acute myocardial infarction of subjects with Type 2 diabetes mellitus
    • Marfella R, Cacciapuoti F, Siniscalchi M, et al. Effect of moderate red wine intake on cardiac prognosis after recent acute myocardial infarction of subjects with Type 2 diabetes mellitus. Diabet Med 2006; 23: 974-81.
    • (2006) Diabet Med , vol.23 , pp. 974-981
    • Marfella, R.1    Cacciapuoti, F.2    Siniscalchi, M.3
  • 65
    • 0034234302 scopus 로고    scopus 로고
    • Cardiopulmonary bypass exacerbates oxidative stress but does not increase proinflammatory cytokine release in patients with diabetes compared with patients without diabetes: Regulatory effects of exogenous nitric oxide
    • Matata BM, Galinanes M. Cardiopulmonary bypass exacerbates oxidative stress but does not increase proinflammatory cytokine release in patients with diabetes compared with patients without diabetes: regulatory effects of exogenous nitric oxide. J Thorac Cardiovasc Surg 2000; 120: 1-11.
    • (2000) J Thorac Cardiovasc Surg , vol.120 , pp. 1-11
    • Matata, B.M.1    Galinanes, M.2
  • 66
    • 3142667617 scopus 로고    scopus 로고
    • Anti-atherosclerotic effects of vitamin E- myth or reality?
    • Munteanu A, Zingg JM, Azzi A. Anti-atherosclerotic effects of vitamin E- myth or reality? J Cell Mol Med 2004; 8: 59-76.
    • (2004) J Cell Mol Med , vol.8 , pp. 59-76
    • Munteanu, A.1    Zingg, J.M.2    Azzi, A.3
  • 67
    • 23944493587 scopus 로고    scopus 로고
    • Vitamin E, oxidative stress, and inflammation
    • Singh U, Devaraj S, Jialal I. Vitamin E, oxidative stress, and inflammation. Annu Rev Nutr 2005; 25: 151-74.
    • (2005) Annu Rev Nutr , vol.25 , pp. 151-174
    • Singh, U.1    Devaraj, S.2    Jialal, I.3
  • 68
    • 24644498663 scopus 로고    scopus 로고
    • Development of atherosclerosis in the diabetic BALB/c mice. Prevention with Vitamin E administration
    • Otero P, Bonet B, Herrera E, Rabano A. Development of atherosclerosis in the diabetic BALB/c mice. Prevention with Vitamin E administration. Atherosclerosis 2005; 182: 259-65.
    • (2005) Atherosclerosis , vol.182 , pp. 259-265
    • Otero, P.1    Bonet, B.2    Herrera, E.3    Rabano, A.4
  • 69
    • 36049008500 scopus 로고    scopus 로고
    • Macrophage NADPH oxidase activation, impaired cholesterol fluxes, and increased cholesterol biosynthesis in diabetic mice: A stimulatory role for D-glucose
    • Hayek T, Kaplan M, Kerry R, Aviram M. Macrophage NADPH oxidase activation, impaired cholesterol fluxes, and increased cholesterol biosynthesis in diabetic mice: a stimulatory role for D-glucose. Atherosclerosis 2007; 195: 277-86.
    • (2007) Atherosclerosis , vol.195 , pp. 277-286
    • Hayek, T.1    Kaplan, M.2    Kerry, R.3    Aviram, M.4
  • 70
    • 0032756355 scopus 로고    scopus 로고
    • The antioxidant function of metallothionein in the heart
    • Kang YJ. The antioxidant function of metallothionein in the heart. Proc Soc Exp Biol Med 1999; 222: 263-73.
    • (1999) Proc Soc Exp Biol Med , vol.222 , pp. 263-273
    • Kang, Y.J.1
  • 71
    • 0021858066 scopus 로고
    • Absorption, transport, and hepatic metabolism of copper and zinc: Special reference to metallothionein and ceruloplasmin
    • Cousins RJ. Absorption, transport, and hepatic metabolism of copper and zinc: special reference to metallothionein and ceruloplasmin. Physiol Rev 1985; 65: 238-309.
    • (1985) Physiol Rev , vol.65 , pp. 238-309
    • Cousins, R.J.1
  • 72
    • 0027533507 scopus 로고
    • Oxygen free radicals and metallothionein
    • Sato M, Bremner I. Oxygen free radicals and metallothionein. Free Radic Biol Med 1993; 14: 325-37.
    • (1993) Free Radic Biol Med , vol.14 , pp. 325-337
    • Sato, M.1    Bremner, I.2
  • 73
    • 0032996361 scopus 로고    scopus 로고
    • Metallothionein in radiation exposure: Its induction and protective role
    • Cai L, Satoh M, Tohyama C, Cherian MG. Metallothionein in radiation exposure: its induction and protective role. Toxicology 1999; 132: 85-98.
    • (1999) Toxicology , vol.132 , pp. 85-98
    • Cai, L.1    Satoh, M.2    Tohyama, C.3    Cherian, M.G.4
  • 74
    • 0034671886 scopus 로고    scopus 로고
    • Metallothionein inhibits peroxynitrite-induced DNA and lipoprotein damage
    • Cai L, Klein JB, Kang YJ. Metallothionein inhibits peroxynitrite-induced DNA and lipoprotein damage. J Biol Chem 2000; 275: 38957-60.
    • (2000) J Biol Chem , vol.275 , pp. 38957-38960
    • Cai, L.1    Klein, J.B.2    Kang, Y.J.3
  • 75
    • 0037433953 scopus 로고    scopus 로고
    • Zinc-metallothionein protects from DNA damage induced by radiation better than glutathione and copper- or cadmium- metallothioneins
    • Cai L, Cherian MG. Zinc-metallothionein protects from DNA damage induced by radiation better than glutathione and copper- or cadmium- metallothioneins. Toxicol Lett 2003; 136: 193-8.
    • (2003) Toxicol Lett , vol.136 , pp. 193-198
    • Cai, L.1    Cherian, M.G.2
  • 76
    • 33749513188 scopus 로고    scopus 로고
    • Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy
    • Cai L, Wang Y, Zhou G, et al. Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy. J Am Coll Cardiol 2006; 48: 1688-97.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1688-1697
    • Cai, L.1    Wang, Y.2    Zhou, G.3
  • 77
    • 20044362943 scopus 로고    scopus 로고
    • Inhibition of superoxide generation and associated nitrosative damage is involved in metallothionein prevention of diabetic cardiomyopathy
    • Cai L, Wang J, Li Y, et al. Inhibition of superoxide generation and associated nitrosative damage is involved in metallothionein prevention of diabetic cardiomyopathy. Diabetes 2005; 54: 1829-37.
    • (2005) Diabetes , vol.54 , pp. 1829-1837
    • Cai, L.1    Wang, J.2    Li, Y.3
  • 78
    • 21244502594 scopus 로고    scopus 로고
    • Cardiac metallothionein synthesis in streptozotocin-induced diabetic mice, and its protection against diabetes- induced cardiac injury
    • Song Y, Wang J, Li Y, et al. Cardiac metallothionein synthesis in streptozotocin-induced diabetic mice, and its protection against diabetes- induced cardiac injury. Am J Pathol 2005; 167: 17-26.
    • (2005) Am J Pathol , vol.167 , pp. 17-26
    • Song, Y.1    Wang, J.2    Li, Y.3
  • 80
    • 0037339706 scopus 로고    scopus 로고
    • Metallothionein prevents diabetes- induced deficits in cardiomyocytes by inhibiting reactive oxygen species production
    • Ye G, Metreveli NS, Ren J, Epstein PN. Metallothionein prevents diabetes- induced deficits in cardiomyocytes by inhibiting reactive oxygen species production. Diabetes 2003; 52: 777-83.
    • (2003) Diabetes , vol.52 , pp. 777-783
    • Ye, G.1    Metreveli, N.S.2    Ren, J.3    Epstein, P.N.4
  • 81
    • 0037200841 scopus 로고    scopus 로고
    • Induction of metallothionein by zinc protects from daunorubicin toxicity in rats
    • Ali MM, Frei E, Straub J, Breuer A, Wiessler M. Induction of metallothionein by zinc protects from daunorubicin toxicity in rats. Toxicology 2002; 179: 85-93.
    • (2002) Toxicology , vol.179 , pp. 85-93
    • Ali, M.M.1    Frei, E.2    Straub, J.3    Breuer, A.4    Wiessler, M.5
  • 82
    • 0034705510 scopus 로고    scopus 로고
    • Modulation of adriamycin toxicity by tissue-specific induction of metallothionein synthesis in mice
    • Satoh M, Naganuma A, Imura N. Modulation of adriamycin toxicity by tissue-specific induction of metallothionein synthesis in mice. Life Sci 2000; 67: 627-34.
    • (2000) Life Sci , vol.67 , pp. 627-634
    • Satoh, M.1    Naganuma, A.2    Imura, N.3
  • 83
    • 33644862200 scopus 로고    scopus 로고
    • Cardiac metallothionein induction plays the major role in the prevention of diabetic cardiomyopathy by zinc supplementation
    • Wang J, Song Y, Elsherif L, et al. Cardiac metallothionein induction plays the major role in the prevention of diabetic cardiomyopathy by zinc supplementation. Circulation 2006; 113: 544-54.
    • (2006) Circulation , vol.113 , pp. 544-554
    • Wang, J.1    Song, Y.2    Elsherif, L.3
  • 84
    • 0031839670 scopus 로고    scopus 로고
    • Resveratrol, a phytoestrogen found in red wine. A possible explanation for the conundrum of the 'French paradox'?
    • Kopp P. Resveratrol, a phytoestrogen found in red wine. A possible explanation for the conundrum of the 'French paradox'? Eur J Endocrinol 1998; 138: 619-20.
    • (1998) Eur J Endocrinol , vol.138 , pp. 619-620
    • Kopp, P.1
  • 85
    • 0034682983 scopus 로고    scopus 로고
    • Cardioprotective effect of resveratrol, a natural antioxidant derived from grapes
    • Hung LM, Chen JK, Huang SS, Lee RS, Su MJ. Cardioprotective effect of resveratrol, a natural antioxidant derived from grapes. Cardiovasc Res 2000; 47: 549-55.
    • (2000) Cardiovasc Res , vol.47 , pp. 549-555
    • Hung, L.M.1    Chen, J.K.2    Huang, S.S.3    Lee, R.S.4    Su, M.J.5
  • 86
    • 0032801975 scopus 로고    scopus 로고
    • The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury
    • Ray PS, Maulik G, Cordis GA, Bertelli AA, Bertelli A, Das DK. The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury. Free Radic Biol Med 1999; 27: 160-9.
    • (1999) Free Radic Biol Med , vol.27 , pp. 160-169
    • Ray, P.S.1    Maulik, G.2    Cordis, G.A.3    Bertelli, A.A.4    Bertelli, A.5    Das, D.K.6
  • 87
    • 34547101726 scopus 로고    scopus 로고
    • Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase
    • Thirunavukkarasu M, Penumathsa SV, Koneru S, et al. Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase. Free Radic Biol Med 2007; 43: 720-9.
    • (2007) Free Radic Biol Med , vol.43 , pp. 720-729
    • Thirunavukkarasu, M.1    Penumathsa, S.V.2    Koneru, S.3
  • 88
    • 39149137233 scopus 로고    scopus 로고
    • Protective mechanisms of resveratrol against ischemia-reperfusion-induced damage in hearts obtained from Zucker obese rats: The role of GLUT-4 and endothelin
    • Lekli I, Szabo G, Juhasz B, et al. Protective mechanisms of resveratrol against ischemia-reperfusion-induced damage in hearts obtained from Zucker obese rats: the role of GLUT-4 and endothelin. Am J Physiol Heart Circ Physiol 2008; 294: H859-66.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294
    • Lekli, I.1    Szabo, G.2    Juhasz, B.3
  • 89
    • 18744424493 scopus 로고    scopus 로고
    • Glutathione peroxidase mimics prevent TNFalpha- and neutrophil-induced endothelial alterations
    • Moutet M, d'Alessio P, Malette P, Devaux V, Chaudière J. Glutathione peroxidase mimics prevent TNFalpha- and neutrophil-induced endothelial alterations. Free Radic Biol Med 1998; 25: 270-81.
    • (1998) Free Radic Biol Med , vol.25 , pp. 270-281
    • Moutet, M.1    d'Alessio, P.2    Malette, P.3    Devaux, V.4    Chaudière, J.5
  • 90
    • 0029440021 scopus 로고
    • Antioxidant and antiinflammatory protection of vascular endothelial cells by new synthetic mimics of glutathione peroxidase
    • Chaudière J, Moutet M, D'Alessio P. Antioxidant and antiinflammatory protection of vascular endothelial cells by new synthetic mimics of glutathione peroxidase. C R Seances Soc Biol Fil 1995; 189: 861-82.
    • (1995) C R Seances Soc Biol Fil , vol.189 , pp. 861-882
    • Chaudière, J.1    Moutet, M.2    D'Alessio, P.3
  • 91
    • 0030218917 scopus 로고    scopus 로고
    • Transgenic mice overexpressing glutathione peroxidase are resistant to myocardial ischemia reperfusion injury
    • Yoshida T, Watanabe M, Engelman DT, et al. Transgenic mice overexpressing glutathione peroxidase are resistant to myocardial ischemia reperfusion injury. J Mol Cell Cardiol 1996; 28: 1759-67.
    • (1996) J Mol Cell Cardiol , vol.28 , pp. 1759-1767
    • Yoshida, T.1    Watanabe, M.2    Engelman, D.T.3
  • 92
    • 10744225549 scopus 로고    scopus 로고
    • Overexpression of glutathione peroxidase prevents left ventricular remodeling and failure after myocardial infarction in mice
    • Shiomi T, Tsutsui H, Matsusaka H, et al. Overexpression of glutathione peroxidase prevents left ventricular remodeling and failure after myocardial infarction in mice. Circulation 2004; 109: 544-9.
    • (2004) Circulation , vol.109 , pp. 544-549
    • Shiomi, T.1    Tsutsui, H.2    Matsusaka, H.3
  • 94
    • 14844345323 scopus 로고    scopus 로고
    • Haptoglobin genotype-and diabetes-dependent differences in iron-mediated oxidative stress in vitro and in vivo
    • Asleh R, Guetta J, Kalet-Litman S, Miller-Lotan R, Levy AP. Haptoglobin genotype-and diabetes-dependent differences in iron-mediated oxidative stress in vitro and in vivo. Circ Res 2005; 96: 435-41.
    • (2005) Circ Res , vol.96 , pp. 435-441
    • Asleh, R.1    Guetta, J.2    Kalet-Litman, S.3    Miller-Lotan, R.4    Levy, A.P.5
  • 95
    • 33845900436 scopus 로고    scopus 로고
    • Haptoglobin genotype determines myocardial infarct size in diabetic mice
    • Blum S, Asaf R, Guetta J, et al. Haptoglobin genotype determines myocardial infarct size in diabetic mice. J Am Coll Cardiol 2007; 49: 82-7.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 82-87
    • Blum, S.1    Asaf, R.2    Guetta, J.3
  • 96
    • 0035146373 scopus 로고    scopus 로고
    • The stable nitroxide, tempol, attenuates the effects of peroxynitrite and oxygen-derived free radicals
    • Thiemermann C, McDonald MC, Cuzzocrea S. The stable nitroxide, tempol, attenuates the effects of peroxynitrite and oxygen-derived free radicals. Crit Care Med 2001; 29: 223-4.
    • (2001) Crit Care Med , vol.29 , pp. 223-224
    • Thiemermann, C.1    McDonald, M.C.2    Cuzzocrea, S.3
  • 97
    • 0036468992 scopus 로고    scopus 로고
    • Effects of the superoxide dismutase-mimetic compound tempol on endothelial dysfunction in streptozotocin-induced diabetic rats
    • Nassar T, Kadery B, Lotan C, Da'as N, Kleinman Y, Haj-Yehia A. Effects of the superoxide dismutase-mimetic compound tempol on endothelial dysfunction in streptozotocin-induced diabetic rats. Eur J Pharmacol 2002; 436: 111-8.
    • (2002) Eur J Pharmacol , vol.436 , pp. 111-118
    • Nassar, T.1    Kadery, B.2    Lotan, C.3    Da'as, N.4    Kleinman, Y.5    Haj-Yehia, A.6
  • 98
    • 23944518894 scopus 로고    scopus 로고
    • Tempol therapy attenuates medial smooth muscle cell apoptosis and neointima formation after balloon catheter injury in carotid artery of diabetic rats
    • Jagadeesha DK, Lindley TE, Deleon J, Sharma RV, Miller F, Bhalla RC. Tempol therapy attenuates medial smooth muscle cell apoptosis and neointima formation after balloon catheter injury in carotid artery of diabetic rats. Am J Physiol Heart Circ Physiol 2005; 289: H1047-53.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Jagadeesha, D.K.1    Lindley, T.E.2    Deleon, J.3    Sharma, R.V.4    Miller, F.5    Bhalla, R.C.6
  • 99
    • 0346098034 scopus 로고    scopus 로고
    • Threshold effects of glucose transporter-4 (GLUT4) deficiency on cardiac glucose uptake and development of hypertrophy
    • Kaczmarczyk SJ, Andrikopoulos S, Favaloro J, et al. Threshold effects of glucose transporter-4 (GLUT4) deficiency on cardiac glucose uptake and development of hypertrophy. J Mol Endocrinol 2003; 31: 449-59.
    • (2003) J Mol Endocrinol , vol.31 , pp. 449-459
    • Kaczmarczyk, S.J.1    Andrikopoulos, S.2    Favaloro, J.3
  • 100
    • 0036157841 scopus 로고    scopus 로고
    • The renin-angiotensin and adrenergic nervous system in cardiac hypertrophy in fructose-fed rats
    • Kamide K, Rakugi H, Higaki J, et al. The renin-angiotensin and adrenergic nervous system in cardiac hypertrophy in fructose-fed rats. Am J Hypertens 2002; 15: 66-71.
    • (2002) Am J Hypertens , vol.15 , pp. 66-71
    • Kamide, K.1    Rakugi, H.2    Higaki, J.3
  • 101
    • 34249710907 scopus 로고    scopus 로고
    • The antioxidant tempol inhibits cardiac hypertrophy in the insulin-resistant GLUT4-deficient mouse in vivo
    • Ritchie RH, Quinn JM, Cao AH, et al. The antioxidant tempol inhibits cardiac hypertrophy in the insulin-resistant GLUT4-deficient mouse in vivo. J Mol Cell Cardiol 2007; 42: 1119-28.
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 1119-1128
    • Ritchie, R.H.1    Quinn, J.M.2    Cao, A.H.3
  • 102
    • 33750349748 scopus 로고    scopus 로고
    • Antioxidants and coronary artery disease among individuals with type 1 diabetes: Findings from the Pittsburgh Epidemiology of Diabetes Complications Study
    • Costacou T, Zgibor JC, Evans RW, Tyurina YY, Kagan VE, Orchard TJ. Antioxidants and coronary artery disease among individuals with type 1 diabetes: Findings from the Pittsburgh Epidemiology of Diabetes Complications Study. J Diabetes Complications 2006; 20: 387-94.
    • (2006) J Diabetes Complications , vol.20 , pp. 387-394
    • Costacou, T.1    Zgibor, J.C.2    Evans, R.W.3    Tyurina, Y.Y.4    Kagan, V.E.5    Orchard, T.J.6
  • 103
    • 7444241367 scopus 로고    scopus 로고
    • The effect of vitamin E supplementation on cardiovascular risk in diabetic individuals with different haptoglobin phenotypes
    • Levy AP, Gerstein HC, Miller-Lotan R, et al. The effect of vitamin E supplementation on cardiovascular risk in diabetic individuals with different haptoglobin phenotypes. Diabetes Care 2004; 27: 2767.
    • (2004) Diabetes Care , vol.27 , pp. 2767
    • Levy, A.P.1    Gerstein, H.C.2    Miller-Lotan, R.3
  • 104
    • 38549138535 scopus 로고    scopus 로고
    • Vitamin E supplementation reduces cardiovascular events in a subgroup of middle-aged individuals with both type 2 diabetes mellitus and the haptoglobin 2-2 genotype: A prospective double-blinded clinical trial
    • Milman U, Blum S, Shapira C, et al. Vitamin E supplementation reduces cardiovascular events in a subgroup of middle-aged individuals with both type 2 diabetes mellitus and the haptoglobin 2-2 genotype: a prospective double-blinded clinical trial. Arterioscler Thromb Vasc Biol 2008; 28: 341-7.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 341-347
    • Milman, U.1    Blum, S.2    Shapira, C.3
  • 105
    • 33747482292 scopus 로고    scopus 로고
    • Effect of moderate red wine intake on cardiac prognosis after recent acute myocardial infarction of subjects with Type 2 diabetes mellitus
    • Marfella R, Cacciapuoti F, Siniscalchi M, et al. Effect of moderate red wine intake on cardiac prognosis after recent acute myocardial infarction of subjects with Type 2 diabetes mellitus. Diabet Med 2006; 23: 974-81.
    • (2006) Diabet Med , vol.23 , pp. 974-981
    • Marfella, R.1    Cacciapuoti, F.2    Siniscalchi, M.3
  • 107
    • 2342563763 scopus 로고    scopus 로고
    • Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes
    • Ye G, Metreveli NS, Donthi RV, et al. Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes. Diabetes 2004; 53: 1336-43.
    • (2004) Diabetes , vol.53 , pp. 1336-1343
    • Ye, G.1    Metreveli, N.S.2    Donthi, R.V.3
  • 108
    • 33644766038 scopus 로고    scopus 로고
    • Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy
    • Shen X, Zheng S, Metreveli NS, Epstein PN. Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy. Diabetes 2006; 55: 798-805.
    • (2006) Diabetes , vol.55 , pp. 798-805
    • Shen, X.1    Zheng, S.2    Metreveli, N.S.3    Epstein, P.N.4
  • 109
    • 33747114039 scopus 로고    scopus 로고
    • Preventing cardiovascular disease and diabetes: A call to action from the American Diabetes Association and the American Heart Association
    • Eckel RH, Kahn R, Robertson RM, Rizza RA. Preventing cardiovascular disease and diabetes: a call to action from the American Diabetes Association and the American Heart Association. Circulation 2006; 113: 2943-6.
    • (2006) Circulation , vol.113 , pp. 2943-2946
    • Eckel, R.H.1    Kahn, R.2    Robertson, R.M.3    Rizza, R.A.4
  • 110
    • 33746465014 scopus 로고    scopus 로고
    • Preventing cardiovascular disease and diabetes: A call to action from the American Diabetes Association and the American Heart Association
    • Eckel RH, Kahn R, Robertson RM, Rizza RA. Preventing cardiovascular disease and diabetes: a call to action from the American Diabetes Association and the American Heart Association. Diabetes Care 2006; 29: 1697-9.
    • (2006) Diabetes Care , vol.29 , pp. 1697-1699
    • Eckel, R.H.1    Kahn, R.2    Robertson, R.M.3    Rizza, R.A.4
  • 111
    • 0035573705 scopus 로고    scopus 로고
    • Is the emperor wearing clothes? Clinical trials of vitamin E and the LDL oxidation hypothesis
    • Heinecke JW. Is the emperor wearing clothes? Clinical trials of vitamin E and the LDL oxidation hypothesis. Arterioscler Thromb Vasc Biol 2001; 21: 1261-4.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1261-1264
    • Heinecke, J.W.1
  • 112
    • 34948814624 scopus 로고    scopus 로고
    • The relationship between dose of vitamin E and suppression of oxidative stress in humans
    • Roberts LJ 2nd, Oates JA, Linton MF, et al. The relationship between dose of vitamin E and suppression of oxidative stress in humans. Free Radic Biol Med 2007; 43: 1388-93.
    • (2007) Free Radic Biol Med , vol.43 , pp. 1388-1393
    • Roberts 2nd, L.J.1    Oates, J.A.2    Linton, M.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.