Fine Mapping of the Sequence Requirements for Binding of β-Lactamase Inhibitory Protein (BLIP) to TEM-1 β-Lactamase Using a Genetic Screen for BLIP Function

Journal of Molecular Biology

Volumn 389, Issue 2, 2009, Pages 401-412

  Yuan, Ji ^a   Huang, Wanzhi ^a   Chow, Dar Chone ^b   Palzkill, Timothy ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b University of Houston   (United States)

Author keywords

antibiotic resistance; enzyme inhibition; molecular recognition; random mutagenesis

Indexed keywords

ALANINE; AMPICILLIN; BACTERIAL DNA; BETA LACTAMASE; BETA LACTAMASE INHIBITORY PROTEIN; BETA LACTAMASE SHV; BETA LACTAMASE TEM 1; INHIBITOR PROTEIN; MUTANT PROTEIN; TETRACYCLINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CHROMOSOME; CONTROLLED STUDY; DNA SEQUENCE; DRUG HYDROLYSIS; ESCHERICHIA COLI; GENE INSERTION; GENE LIBRARY; GENE LOCUS; GENETIC ANALYSIS; GENETIC SCREENING; MINIMUM INHIBITORY CONCENTRATION; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; STRAIN DIFFERENCE; WILD TYPE;

ESCHERICHIA COLI;

EID: 65549164398     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.04.028     Document Type: Article

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