Recent advances in structure-based virtual screening of G-Protein coupled receptors

AAPS Journal

Volumn 11, Issue 1, 2009, Pages 178-185

  Ananthan, Subramaniam ^a   Zhang, Wei ^a   Hobrath, Judith Varady ^a  

^a SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

GPCRs; Homology modeling; Virtual screening

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1A ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; CARAZOLOL; CARVEDILOL; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CORTICOTROPIN RELEASING FACTOR RECEPTOR; DOPAMINE 2 RECEPTOR; G PROTEIN COUPLED RECEPTOR; GLUCAGON RECEPTOR; GUANIDINE DERIVATIVE; HISTAMINE H4 RECEPTOR; KAPPA OPIATE RECEPTOR; MELANIN CONCENTRATING HORMONE RECEPTOR 1; MELANIN CONCENTRATING HORMONE RECEPTOR 1 ANTAGONIST; METABOTROPIC RECEPTOR 5; PROTIRELIN RECEPTOR; RETINAL; SALVINORIN A;

CRYSTAL STRUCTURE; DRUG IDENTIFICATION; DRUG SCREENING; DRUG STRUCTURE; HIGH THROUGHPUT SCREENING; MOLECULAR DOCKING; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; SHORT SURVEY; VIRTUAL REALITY;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; HORMONES; HUMANS; LIGANDS; MODELS, CHEMICAL; MODELS, MOLECULAR; NEUROTRANSMITTER AGENTS; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROTRANSMITTER; RECEPTORS, PEPTIDE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 65549163531     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/s12248-009-9094-3     Document Type: Short Survey

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