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Volumn 4, Issue 1, 2009, Pages 67-70

Structurally modified 'dietary flavonoids': Are these viable drug candidates for chemoprevention?

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; APIGENIN; CHRYSIN; FLAVONE DERIVATIVE; FLAVONOID; GENISTEIN; NATURAL PRODUCT; PHYTOESTROGEN; POLYPHENOL DERIVATIVE; QUERCETIN; SELENIUM; TAMOXIFEN; VITAMIN D; ANTINEOPLASTIC AGENT;

EID: 65549160008     PISSN: 15748847     EISSN: None     Source Type: Journal    
DOI: 10.2174/157488409787236065     Document Type: Review
Times cited : (13)

References (30)
  • 1
    • 34248137632 scopus 로고    scopus 로고
    • The true face of the revolution in oncology drug development: A personal reflection
    • Burgess M, de Alwis DP. The true face of the revolution in oncology drug development: A personal reflection. Curr Clin Pharmacol 2007; 2: 31-5.
    • (2007) Curr Clin Pharmacol , vol.2 , pp. 31-35
    • Burgess, M.1    de Alwis, D.P.2
  • 3
    • 0028816898 scopus 로고
    • Cancer chemoprevention agent development strategies for genistein
    • Steele VE, Pereira MA, Sigman CC, Kelloff GJ. Cancer chemoprevention agent development strategies for genistein. J Nutr 1995; 125: 713S-6S.
    • (1995) J Nutr , vol.125
    • Steele, V.E.1    Pereira, M.A.2    Sigman, C.C.3    Kelloff, G.J.4
  • 4
    • 43149124983 scopus 로고    scopus 로고
    • Biomarkers of dietary intake of flavonoids and phenolic acids for studying diet-cancer relationships in humans
    • Linseise J, Rohrmann S. Biomarkers of dietary intake of flavonoids and phenolic acids for studying diet-cancer relationships in humans. Eur J Nutr 2008; 47: 60-8.
    • (2008) Eur J Nutr , vol.47 , pp. 60-68
    • Linseise, J.1    Rohrmann, S.2
  • 5
    • 0032785391 scopus 로고    scopus 로고
    • Green tea and cacer chemoprevention
    • Suganuma M, Okabe S, Sueoka N, et al. Green tea and cacer chemoprevention. Mutat Res 1999; 428: 339-44.
    • (1999) Mutat Res , vol.428 , pp. 339-344
    • Suganuma, M.1    Okabe, S.2    Sueoka, N.3
  • 6
    • 27644546239 scopus 로고    scopus 로고
    • Anthocyans from fruits and vegetables - does bright colour signal cancer chemopreventive activity?
    • Cooke D, Steward WP, Gescher AJ, Marczylo T. Anthocyans from fruits and vegetables - does bright colour signal cancer chemopreventive activity? Eur J Cancer 2005; 41: 1931-40.
    • (2005) Eur J Cancer , vol.41 , pp. 1931-1940
    • Cooke, D.1    Steward, W.P.2    Gescher, A.J.3    Marczylo, T.4
  • 7
    • 65649094640 scopus 로고    scopus 로고
    • http://www.phytochemicals.info/phytochemicals/flavonoids.php (this website provides a description of various types of phytochemicals including flavonoids).
    • http://www.phytochemicals.info/phytochemicals/flavonoids.php (this website provides a description of various types of phytochemicals including flavonoids).
  • 9
    • 30644456411 scopus 로고    scopus 로고
    • Dietary flavonoids: Effects on xenobiotic and carcinogen metabolism
    • Moon YJ, Wang X, Morris ME. Dietary flavonoids: effects on xenobiotic and carcinogen metabolism. Toxicology 2006; 20: 187-210.
    • (2006) Toxicology , vol.20 , pp. 187-210
    • Moon, Y.J.1    Wang, X.2    Morris, M.E.3
  • 10
    • 37549040537 scopus 로고    scopus 로고
    • Metabolism and bioavailability of flavonoids in chemprevention: Current analytical strategies and future prospectus
    • Prasain JK, Barnes S. Metabolism and bioavailability of flavonoids in chemprevention: current analytical strategies and future prospectus. Mol Pharm 2007; 4: 846-64.
    • (2007) Mol Pharm , vol.4 , pp. 846-864
    • Prasain, J.K.1    Barnes, S.2
  • 11
    • 34548287203 scopus 로고    scopus 로고
    • Aromatase inhibition by bioavailable methylated flavones
    • Ta N, Walle T. Aromatase inhibition by bioavailable methylated flavones. J Steroid Biochem Mol Biol 2007; 107: 127-9.
    • (2007) J Steroid Biochem Mol Biol , vol.107 , pp. 127-129
    • Ta, N.1    Walle, T.2
  • 12
    • 34548267589 scopus 로고    scopus 로고
    • Improving metabolic stability of cancer chemopreventive polyphenols
    • Walle T, Wen X, Walle UK. Improving metabolic stability of cancer chemopreventive polyphenols. Toxicology 2007; 3: 379-88.
    • (2007) Toxicology , vol.3 , pp. 379-388
    • Walle, T.1    Wen, X.2    Walle, U.K.3
  • 13
    • 33745083616 scopus 로고    scopus 로고
    • Methylation protects dietary flavonoids from rapid hepatic metabolism
    • Wen X, Walle T. Methylation protects dietary flavonoids from rapid hepatic metabolism. Xenobiotica 2006; 36: 387-97.
    • (2006) Xenobiotica , vol.36 , pp. 387-397
    • Wen, X.1    Walle, T.2
  • 14
    • 33748916241 scopus 로고    scopus 로고
    • Methylated flavonoids have greatly improved intestinal absorption and metabolic stability
    • Wen X, Walle T. Methylated flavonoids have greatly improved intestinal absorption and metabolic stability. Drug Metab Dispos 2006; 34: 1786-92.
    • (2006) Drug Metab Dispos , vol.34 , pp. 1786-1792
    • Wen, X.1    Walle, T.2
  • 15
    • 34548423695 scopus 로고    scopus 로고
    • Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass
    • Walle T. Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass. Semin Cancer Biol 2007; 17: 354-62.
    • (2007) Semin Cancer Biol , vol.17 , pp. 354-362
    • Walle, T.1
  • 16
    • 33947359919 scopus 로고    scopus 로고
    • Cancer chemopreventive properties of orally bioavailable flavonoids - methylated versus unmethylated flavones
    • Walle T, Ta N, Kawamori T, Wen X, Tsuji PA, Walle UK. Cancer chemopreventive properties of orally bioavailable flavonoids - methylated versus unmethylated flavones. Biochem Pharmacol 2007; 73: 1288-96.
    • (2007) Biochem Pharmacol , vol.73 , pp. 1288-1296
    • Walle, T.1    Ta, N.2    Kawamori, T.3    Wen, X.4    Tsuji, P.A.5    Walle, U.K.6
  • 17
    • 37549024168 scopus 로고    scopus 로고
    • Methylation of dietary flavones greatly improves their hepatic metabolic stability and intestinal absorption
    • Walle T. Methylation of dietary flavones greatly improves their hepatic metabolic stability and intestinal absorption. Mol Pharm 2007; 4: 826-7.
    • (2007) Mol Pharm , vol.4 , pp. 826-827
    • Walle, T.1
  • 18
    • 34248350462 scopus 로고    scopus 로고
    • Tissue distribution in mice and metabolism in murine and human liver of apigenin and tricin, flavones with putative cancer chemopreventive properties
    • Cai H, Boocock DJ, Steward WP, Geschler AJ. Tissue distribution in mice and metabolism in murine and human liver of apigenin and tricin, flavones with putative cancer chemopreventive properties. Cancer Chemother Pharmacol 2007; 60: 257-66.
    • (2007) Cancer Chemother Pharmacol , vol.60 , pp. 257-266
    • Cai, H.1    Boocock, D.J.2    Steward, W.P.3    Geschler, A.J.4
  • 19
    • 33645294093 scopus 로고    scopus 로고
    • Enhanced bioavailability of tamoxifen after oral administration of tamoxifen with quercetin in rats
    • Shin SC, Choi JS, Li X. Enhanced bioavailability of tamoxifen after oral administration of tamoxifen with quercetin in rats. Int J Pharm 2006; 313: 144-9.
    • (2006) Int J Pharm , vol.313 , pp. 144-149
    • Shin, S.C.1    Choi, J.S.2    Li, X.3
  • 20
    • 27744435377 scopus 로고    scopus 로고
    • Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 cells
    • Smith CM, Graham RA, Krol WL, et al. Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 cells. J Pharmacol Exp Ther 2005; 315: 1256-64.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 1256-1264
    • Smith, C.M.1    Graham, R.A.2    Krol, W.L.3
  • 22
    • 33846598505 scopus 로고    scopus 로고
    • Pharmacokinetics of tramadol enantiomers and their respective phase I metabolites in relation to CYP2D6 phenotype
    • García-Quetglas E, Azanza JR, Sadaba B, Munoz MJ, Gil I, Campanero MA. Pharmacokinetics of tramadol enantiomers and their respective phase I metabolites in relation to CYP2D6 phenotype. Pharmacol Res 2007; 55: 122-30.
    • (2007) Pharmacol Res , vol.55 , pp. 122-130
    • García-Quetglas, E.1    Azanza, J.R.2    Sadaba, B.3    Munoz, M.J.4    Gil, I.5    Campanero, M.A.6
  • 23
    • 54849416116 scopus 로고    scopus 로고
    • Relationship between the methylation status of dietary flavonoids and their growth-inhibitory and apoptosis-inducing activities in human cancer cells
    • Landis-Piwowar KR, Milacic V, Dou QP. Relationship between the methylation status of dietary flavonoids and their growth-inhibitory and apoptosis-inducing activities in human cancer cells. J Cell Biochem 2008; 105: 514-23.
    • (2008) J Cell Biochem , vol.105 , pp. 514-523
    • Landis-Piwowar, K.R.1    Milacic, V.2    Dou, Q.P.3
  • 24
    • 33845645957 scopus 로고    scopus 로고
    • Cytochrome P450 1B1, a novel chemopreventive target for benzo1pyrene-initiated human esophageal cancer
    • Wen X, Walle T. Cytochrome P450 1B1, a novel chemopreventive target for benzo1pyrene-initiated human esophageal cancer. Cancer Lett 2007; 246: 109-14.
    • (2007) Cancer Lett , vol.246 , pp. 109-114
    • Wen, X.1    Walle, T.2
  • 25
    • 34447319174 scopus 로고    scopus 로고
    • Novel methoxylated flavone inhibitors of cytochrome P450 1B1 in SCC-9 human oral cancer cells
    • Walle T, Walle UK. Novel methoxylated flavone inhibitors of cytochrome P450 1B1 in SCC-9 human oral cancer cells. J Pharm Pharmacol 2007; 59: 857-62.
    • (2007) J Pharm Pharmacol , vol.59 , pp. 857-862
    • Walle, T.1    Walle, U.K.2
  • 26
    • 0036035557 scopus 로고    scopus 로고
    • Further investigation of the modifying effect of various chemopreventive agents on apoptosis and cell proliferation in human colon cancer cells
    • Zheng Q, Hirose Y, Yoshimi Y, et al. Further investigation of the modifying effect of various chemopreventive agents on apoptosis and cell proliferation in human colon cancer cells. J Cancer Res Clin Oncol 2002; 128: 539-46.
    • (2002) J Cancer Res Clin Oncol , vol.128 , pp. 539-546
    • Zheng, Q.1    Hirose, Y.2    Yoshimi, Y.3
  • 27
    • 38849192322 scopus 로고    scopus 로고
    • Chemoprevention of prostrate cancer through dietary agents: Progress and promise
    • Syed DN, Khan N, Afaq F, Mukhtar H. Chemoprevention of prostrate cancer through dietary agents: progress and promise. Cancer Epidemiol Biomarkers Prev 2007; 16: 2193-2203.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 2193-2203
    • Syed, D.N.1    Khan, N.2    Afaq, F.3    Mukhtar, H.4
  • 29
    • 33746983762 scopus 로고    scopus 로고
    • Inhibitory effects of fruit juices on CYP3A activity
    • Kim H, Yoon YJ, Shon JH, et al. Inhibitory effects of fruit juices on CYP3A activity. Drug Metab Dispos 2006; 34: 521-3.
    • (2006) Drug Metab Dispos , vol.34 , pp. 521-523
    • Kim, H.1    Yoon, Y.J.2    Shon, J.H.3
  • 30
    • 65649085035 scopus 로고    scopus 로고
    • Clinical use of St. John's wort: Drug-drug interaction potential of the marketed products and challenges for drug development
    • Srinivas NR. Clinical use of St. John's wort: drug-drug interaction potential of the marketed products and challenges for drug development. Asian J Pharmacodyn Pharmacokin 2008; 8: 109-26.
    • (2008) Asian J Pharmacodyn Pharmacokin , vol.8 , pp. 109-126
    • Srinivas, N.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.