메뉴 건너뛰기




Volumn 50, Issue 26, 2009, Pages 3205-3208

Design and synthesis of immobilized Tamiflu analog on resin for affinity chromatography

Author keywords

Abnormal behavior; Affinity chromatography; Immobilization; Neuraminidase; Tamiflu

Indexed keywords

ANTIVIRUS AGENT; OSELTAMIVIR; OSELTAMIVIR DERIVATIVE; RESIN; SIALIDASE; UNCLASSIFIED DRUG; VIRUS ENZYME;

EID: 65549152349     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.01.142     Document Type: Article
Times cited : (17)

References (30)
  • 2
    • 33646567839 scopus 로고    scopus 로고
    • For studies on the synthesis of Tamiflu, see:
    • For studies on the synthesis of Tamiflu, see:. Yueng Y.-Y., Hong S., and Corey E.J. J. Am. Chem. Soc. 128 (2006) 6310
    • (2006) J. Am. Chem. Soc. , vol.128 , pp. 6310
    • Yueng, Y.-Y.1    Hong, S.2    Corey, E.J.3
  • 17
    • 65549086533 scopus 로고    scopus 로고
    • For reviews on the synthesis of Tamiflu, see:
    • For reviews on the synthesis of Tamiflu, see:. Farina N., and Brown J.D. Angew. Chem., Int. Ed. 45 (2006) 7300
    • (2006) Angew. Chem., Int. Ed. , vol.45 , pp. 7300
    • Farina, N.1    Brown, J.D.2
  • 23
    • 5044224236 scopus 로고    scopus 로고
    • According to the Ministry of Health, is no relationship between Tamiflu administration and abnormal behaviors based on animal experiments performed by the Chugai Pharmaceutical Company, which sells Tamiflu in Japan. For details, see, http://www.chugai-pharm.co.jp/html/info/071210.html
    • According to the Ministry of Health, Labor, and Welfare of Japan, there is no relationship between Tamiflu administration and abnormal behaviors based on animal experiments performed by the Chugai Pharmaceutical Company, which sells Tamiflu in Japan. For details, see http://www.mhlw.go.jp/shingi/2007/12/s1210-6.html, http://www.chugai-pharm.co.jp/html/info/071210.html.
    • Labor, and Welfare of Japan, there
  • 27
    • 65549097644 scopus 로고    scopus 로고
    • The reaction with 4 equiv or 10 equiv of the alcohol gave low yields (approximately 20% and 40, respectively) of the ether 16
    • The reaction with 4 equiv or 10 equiv of the alcohol gave low yields (approximately 20% and 40%, respectively) of the ether 16.
  • 28
    • 65549120268 scopus 로고    scopus 로고
    • 4 afforded a complex mixture.
    • 4 afforded a complex mixture.
  • 29
    • 65549137053 scopus 로고    scopus 로고
    • Approximately, 40% of unreacted 20b was recovered based on NMR analysis of the combined solution phases.
    • Approximately, 40% of unreacted 20b was recovered based on NMR analysis of the combined solution phases.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.