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According to the Ministry of Health, Labor, and Welfare of Japan, there is no relationship between Tamiflu administration and abnormal behaviors based on animal experiments performed by the Chugai Pharmaceutical Company, which sells Tamiflu in Japan. For details, see http://www.mhlw.go.jp/shingi/2007/12/s1210-6.html, http://www.chugai-pharm.co.jp/html/info/071210.html.
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For the synthesis of 5-azido-1-pentanol, see:
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65549097644
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The reaction with 4 equiv or 10 equiv of the alcohol gave low yields (approximately 20% and 40, respectively) of the ether 16
-
The reaction with 4 equiv or 10 equiv of the alcohol gave low yields (approximately 20% and 40%, respectively) of the ether 16.
-
-
-
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28
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65549120268
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4 afforded a complex mixture.
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4 afforded a complex mixture.
-
-
-
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29
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65549137053
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Approximately, 40% of unreacted 20b was recovered based on NMR analysis of the combined solution phases.
-
Approximately, 40% of unreacted 20b was recovered based on NMR analysis of the combined solution phases.
-
-
-
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30
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47649092577
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Ullrich T., Ghobrial M., Peters C., Billich A., Guerini D., and Nussbaumer P. Chem. Med. Chem. 3 (2007) 356
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