Chapter 18 Analysis of Chemokine Receptor Endocytosis and Intracellular Trafficking

Methods in Enzymology

Volumn 460, Issue A, 2009, Pages 357-377

  Kershaw, Tom ^a   Wavre Shapton, Silène T ^c   Signoret, Nathalie ^b   Marsh, Mark ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b UNIVERSITY OF HULL   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR5;

ANTIBODY LABELING; CELL MEMBRANE; CELL MIGRATION; CELL SURFACE; DEGRADATION; ELECTRON MICROSCOPY; ENDOCYTOSIS; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE SYSTEM; IMMUNOFLUORESCENCE; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOGOLD LABELING; INTERNALIZATION; MALARIA; MONITORING; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVIEW; WESTERN BLOTTING; ANIMAL; ARTICLE; CHO CELL; CRICETULUS; FLUORESCENCE MICROSCOPY; GENETICS; HAMSTER; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT;

HUMAN IMMUNODEFICIENCY VIRUS;

ANIMALS; BLOTTING, WESTERN; CHO CELLS; CRICETINAE; CRICETULUS; ENDOCYTOSIS; FLOW CYTOMETRY; HUMANS; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; PROTEIN TRANSPORT; RECEPTORS, CHEMOKINE;

EID: 65549138877     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(09)05218-5     Document Type: Review

References (37)

1. Baba M., Nishimura O., Kanzaki N., Okamoto M., Sawada H., Iizawa Y., Shiraishi M., Aramaki Y., Okonogi K., Ogawa Y., Meguro K., and Fujino M. A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity. Proc. Natl. Acad. Sci. USA 96 (1999) 5698-5703
2. Blanpain C., Vanderwinden J.M., Cihak J., Wittamer V., Le Poul E., Issafras H., Stangassinger M., Vassart G., Marullo S., Schlndorff D., Parmentier M., and Mack M. Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies. Mol. Biol. Cell 13 (2002) 723-737
3. Defea K. Beta-arrestins and heterotrimeric G-proteins: Collaborators and competitors in signal transduction. Br. J. Pharmacol. 153 Suppl 1 (2008) S298-S309
4. Delhaye M., Gravot A., Ayinde D., Niedergang F., Alizon M., and Brelot A. Identification of a postendocytic sorting sequence in CCR5. Mol. Pharmacol. 72 (2007) 1497-1507
5. Endres M.J., Clapham P.R., Marsh M., Ahuja M., Davis-Turner J., McKnight A., Thomas J., Stoebenau-Haggarty B., Choe S., Vance P.J., Wells T.N.C., Power C.A., et al. CD4-independent infection by HIV-2 is mediated by fusin. Cell 87 (1996) 745-756
6. Fraile-Ramos A., Kohout T., Waldhoer M., and Marsh M. Endocytosis of the viral chemokine receptor US28 does not require beta-arrestins but is dependent on the clathrin-mediated pathway. Traffic 4 (2003) 243-253
7. Hanyaloglu A.C., and von Zastrow M. Regulation of GPCRs by endocytic membrane trafficking and its potential implications. Annu. Rev. Pharmacol. Toxicol. 48 (2008) 537-568
8. Hill C.M., Kwon D., Jones M., Davis C.B., Marmon S., Daugherty B.L., DeMartino J.A., Springer M.S., Unutmaz D., and Littman D.R. The amino terminus of human CCR5 is required for its function as a receptor for diverse human and simian immunodeficiency virus envelope glycoproteins. Virology 248 (1998) 357-371
9. Huttenrauch F., Pollok-Kopp B., and Oppermann M. G protein-coupled receptor kinases promote phosphorylation and beta-arrestin-mediated internalization of CCR5 homo- and hetero-oligomers. J. Biol. Chem. 280 (2005) 37503-37515
10. Klasse P.J., Rosenkilde M.M., Signoret N., Pelchen-Matthews A., Schwartz T.W., and Marsh M. CD4-chemokine-receptor hybrids in human immunodeficiency virus type 1 (HIV-1) infection. J. Virol. 73 (1999) 7453-7466
11. Lee B., Sharron M., Blanpain C., Doranz B.J., Vakili J., Setoh P., Berg E., Liu G., Guy H.R., Durell S.R., Parmentier M., Chang C.N., et al. Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function. J. Biol. Chem. 274 (1999) 9617-9626
12. Lusso P. HIV and the chemokine system: 10 years later. EMBO J. 25 (2006) 447-456
13. Mack M., Luckow B., Nelson P.J., Cihak J., Simmons G., Clapham P.R., Signoret N., Marsh M., Stangassinger M., Borlat F., Wells T.N.C., Schlondorff D., and Proudfoot A.E. Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: A novel inhibitory mechanism of HIV infectivity. J. Exp. Med. 187 (1998) 1215-1224
14. Marchese A., Raiborg C., Santini F., Keen J.H., Stenmark H., and Benovic J.L. The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4. Dev. Cell 5 (2003) 709-722
15. Marsh M., and Helenius A. Adsorptive endocytosis of Semliki Forest virus. J. Mol. Biol. 142 (1980) 439-454
16. Martinez M.A., Gutierrez A., Armand-Ugon M., Blanco J., Parera M., Gomez J., Clotet B., and Este J.A. Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication. AIDS 16 (2002) 2385-2390
17. McKnight A., Wilkinson D., Simmons G., Talbot S., Picard L., Ahuja M., Marsh M., Hoxie J.A., and Clapham P.R. Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependent. J. Virol. 71 (1997) 1692-1696
18. McLean A.J., and Milligan G. Ligand regulation of green fluorescent protein-tagged forms of the human beta(1)- and beta(2)-adrenoceptors; comparisons with the unmodified receptors. Br. J. Pharmacol. 130 (2000) 1825-1832
19. Miller K., Shipman M., Trowbridge I.S., and Hopkins C.R. Transferrin receptors promote the formation of clathrin lattices. Cell 65 (1991) 621-632
20. Murphy P.M., Baggiolini M., Charo I.F., Hebert C.A., Horuk R., Matsushima K., Miller L.H., Oppenheim J.J., and Power C.A. International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol. Rev. 52 (2000) 145-176
21. Pelchen-Matthews A., Armes J.E., and Marsh M. Internalization and recycling of CD4 transfected into HeLa and NIH-3T3 cells. EMBO J. 8 (1989) 3641-3649
22. Pelchen-Matthews A., and Marsh M. EM analysis of viral morphogenesis. Methods Cell Biol. 79 (2007) 515-542
23. Sallusto F., and Baggiolini M. Chemokines and leukocyte traffic. Nat. Immunol. 9 (2008) 949-952
24. Sanan D.A., and Anderson R.G. Simultaneous visualization of LDL receptor distribution and clathrin lattices on membranes torn from the upper surface of cultured cells. J. Histochem. Cytochem. 39 (1991) 1017-1024
25. Schulte G., and Levy F.O. Novel aspects of G-protein-coupled receptor signalling-Different ways to achieve specificity. Acta Physiol. (Oxford) 190 (2007) 33-38
26. Segerer S., Mack M., Regele H., Kerjaschki D., and Schlondorff D. Expression of the C-C chemokine receptor 5 in human kidney diseases. Kidney Int. 56 (1999) 52-64
27. Shiraishi M., Aramaki Y., Seto M., Imoto H., Nishikawa Y., Kanzaki N., Okamoto M., Sawada H., Nishimura O., Baba M., and Fujino M. Discovery of novel, potent, and selective small-molecule CCR5 antagonists as anti-HIV-1 agents: Synthesis and biological evaluation of anilide derivatives with a quaternary ammonium moiety. J. Med. Chem. 43 (2000) 2049-2063
28. Signoret N., Christophe T., Oppermann M., and Marsh M. pH-independent endocytic cycling of the chemokine receptor CCR5. Traffic 5 (2004) 529-543
29. Signoret N., Hewlett L., Wavre S., Pelchen-Matthews A., Oppermann M., and Marsh M. Agonist-induced endocytosis of CC chemokine receptor 5 is clathrin dependent. Mol. Biol. Cell 16 (2005) 902-917
30. Signoret N., and Marsh M. Analysis of chemokine receptor endocytosis and recycling. Methods Mol. Biol. 138 (2000) 197-207
31. Signoret N., Oldridge J., Pelchen-Matthews A., Klasse P.J., Tran T., Brass L.F., Rosenkilde M.M., Schwartz T.W., Holmes W., Dallas W., Luther M.A., Wells T.N.C., Hoxie J.A., and Marsh M. Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4. J. Cell Biol. 139 (1997) 651-664
32. Signoret N., Pelchen-Matthews A., Mack M., Proudfoot A.E.I., and Marsh M. Endocytosis and recycling of the HIV co-receptor CCR5. J. Cell Biol. 151 (2000) 1281-1294
33. Simmons G., Reeves J.D., Hibbitts S., Stine J.T., Gray P.W., Proudfoot A.E., and Clapham P.R. Co-receptor use by HIV and inhibition of HIV infection by chemokine receptor ligands. Immunol. Rev. 177 (2000) 112-126
34. Slot J.W., and Geuze H.J. Cryosectioning and immunolabeling. Nat. Protocols 2 (2007) 2480-2491
35. Tarasova N.I., Stauber R.H., and Michejda C.J. Spontaneous and ligand-induced trafficking of CXC-chemokine receptor 4. J. Biol. Chem. 273 (1998) 15883-15886
36. Verani A., and Lusso P. Chemokines as natural HIV antagonists. Curr. Mol. Med. 2 (2002) 691-702
37. Zanussi S., D'Andrea M., Simonelli C., Tirelli U., and De Paoli P. Serum levels of RANTES and MIP-1 alpha in HIV-positive long-term survivors and progressor patients. AIDS 10 (1996) 1431-1432