Ultra scale-down of protein refold screening in microwells: Challenges, solutions and application

Biotechnology and Bioengineering

Volumn 103, Issue 2, 2009, Pages 329-340

  Mannall, Gareth J ^a   Myers, James P ^b   Liddell, John ^c   Titchener Hooker, Nigel J ^a   Dalby, Paul A ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b BioPharm Services UK   (United Kingdom)

^c Avecia Biologics   (United Kingdom)

Author keywords

High throughput screening; IGF 1; Lysozyme; Mixing; Refolding; Ultra scale down

Indexed keywords

HIGH-THROUGHPUT SCREENING; IGF-1; LYSOZYME; REFOLDING; ULTRA SCALE-DOWN;

ASSAYS; BIOCHEMISTRY; ENZYME ACTIVITY; MICROCHANNELS; MIXING; TURBIDITY;

ENZYMES;

EGG WHITE; LYSOZYME; SOMATOMEDIN C; EGG PROTEIN;

ARTICLE; CALIBRATION; CELL INCLUSION; DENATURATION; ENZYME ACTIVITY; EVALUATION; EXPERIMENTATION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN SYNTHESIS; SCALE UP; TURBIDITY; CHEMISTRY; METABOLISM; PROTEIN CONFORMATION;

EGG PROTEINS; INSULIN-LIKE GROWTH FACTOR I; MURAMIDASE; PROTEIN CONFORMATION; PROTEIN FOLDING;

EID: 65549094031     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22245     Document Type: Article

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