An automated microscale chromatographic purification of virus-like particles as a strategy for process development

Biotechnology and Applied Biochemistry

Volumn 47, Issue 2, 2007, Pages 131-139

  Wenger, Marc D ^a,b   Dephillips, Peter ^b   Price, Colleen E ^b   Bracewell, Daniel G ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Automation; Bioprocess; Fermentation; Human papillomavirus; Microscale chromatography; Virus like particle (VLP)

Indexed keywords

AGGLOMERATION; AUTOMATION; FERMENTATION; LIQUID CHROMATOGRAPHY; PURIFICATION; VACCINES;

BIOPROCESSES; HUMAN PAPILLOMAVIRUS; MICROSCALE CHROMATOGRAPHY; VIRUS-LIKE PARTICLE (VLP);

VIRUSES;

RECOMBINANT VACCINE;

ARTICLE; BIOLOGICAL MODEL; CHROMATOGRAPHY; CONTROLLED STUDY; ELECTRONICS; FERMENTATION TECHNIQUE; LABORATORY AUTOMATION; METHODOLOGY; NONHUMAN; PROCESS DEVELOPMENT; SACCHAROMYCES CEREVISIAE; VIRUS LIKE AGENT; VIRUS PURIFICATION; WART VIRUS; YEAST;

CHROMATOGRAPHY, LIQUID; MICROFLUIDICS; MINIATURIZATION; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS VACCINES; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; VIRION; VIRUS CULTIVATION;

HUMAN PAPILLOMAVIRUS; SACCHAROMYCES CEREVISIAE;

EID: 34249873258     PISSN: 08854513     EISSN: None     Source Type: Journal    
DOI: 10.1042/BA20060240     Document Type: Article

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