Factors affecting protein refolding yields in a fed-batch and batch-refolding system

Biotechnology and Bioengineering

Volumn 97, Issue 6, 2007, Pages 1523-1534

  Mannall, Gareth J ^a   Titchener Hooker, Nigel J ^a   Dalby, Paul A ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Chaotrope concentration; Fed batch; Mixing; Redox ratio; Refolding

Indexed keywords

CONCENTRATION (PROCESS); ESCHERICHIA COLI; OXIDATION; REDOX REACTIONS;

CHAOTROPE CONCENTRATION; FED BATCH; REDOX RATIO; REFOLDING;

PROTEIN FOLDING;

BUFFER; GUANIDINE; LYSOZYME;

ARTICLE; DILUTION; ENZYME ASSAY; FED BATCH CULTURE; IMPELLER; OXIDATION REDUCTION REACTION; PROTEIN DENATURATION; PROTEIN FOLDING; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

BIOREACTORS; COMBINATORIAL CHEMISTRY TECHNIQUES; COMPUTER SIMULATION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; INCLUSION BODIES; MODELS, BIOLOGICAL; PROTEIN ENGINEERING; PROTEIN FOLDING; RECOMBINANT PROTEINS;

ESCHERICHIA COLI;

EID: 34547636911     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21377     Document Type: Article

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