New high-throughput fluorimetric assay for discovering inhibitors of UDP-N-Acetylmuramyl-l-Alanine: D-Glutamate (MurD) Ligase

Journal of Biomolecular Screening

Volumn 14, Issue 4, 2009, Pages 412-418

  Kristan, Katja ^a   Kotnik, Miha ^a   Oblak, Marko ^a   Urleb, Uroŝ ^a  

^a Lek dd   (Slovenia)

Author keywords

Cell wall biosynthesis; Fluorimetric assay; High throughput screening; Mur ligases; MurD inhibitors

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ALANINE DERIVATIVE; BETA,GAMMA METHYLENEADENOSINE TRIPHOSPHATE; DEXTRO GLUTAMIC ACID; LIGASE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE N ACETYLMURAMYL ALANINE; URIDINE DIPHOSPHATE N ACETYLMURAMYL ALANINE DEXTRO GLUTAMATE LIGASE;

ARTICLE; CATALYSIS; ENZYME ACTIVATION; FLUORESCENCE; FLUOROMETRY; HIGH THROUGHPUT SCREENING; IC 50; INHIBITION KINETICS; NONHUMAN; PERFORMANCE; PRIORITY JOURNAL; SCREENING; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; ENZYME INHIBITORS; ESCHERICHIA COLI; FLUOROMETRY; GLUTAMIC ACID; INHIBITORY CONCENTRATION 50; KINETICS; PEPTIDE SYNTHASES; SMALL MOLECULE LIBRARIES; URIDINE DIPHOSPHATE N-ACETYLMURAMIC ACID;

BACTERIA (MICROORGANISMS);

EID: 65449184560     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057109332597     Document Type: Article

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