Study of the reaction mechanism of the D-glutamic acid-adding enzyme from Escherichia coli

Microbial Drug Resistance

Volumn 2, Issue 1, 1996, Pages 51-54

  Vaganay, Sabine ^a   Tanner, Martin E ^b   Van Heijenoort, Jean ^a   Blanot, Didier ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

5,5' DITHIOBIS(2 NITROBENZOIC ACID); ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ALANINE; BACTERIAL ENZYME; BENZOIC ACID DERIVATIVE; DIPEPTIDE DERIVATIVE; ENZYME INHIBITOR; GLUTAMIC ACID; PHOSPHATE; TETRANITROMETHANE; TRINITROBENZENESULFONIC ACID; URIDINE DIPHOSPHATE N ACETYLMURAMIC ACID;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME PURIFICATION; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0029739897     PISSN: 10766294     EISSN: None     Source Type: Journal    
DOI: 10.1089/mdr.1996.2.51     Document Type: Article

References (25)

1. Auger, G., J. van Heijenoort, D. Blanot, and C. Deprun. 1995. Synthesis of N-acetylmuramic acid derivatives as potential inhibitors of the D-glutamic acid-adding enzyme. J. Prakt. Chem. 337:351-357.
2. Barnard, G., H. Roy, and Y.P. Myer. 1983. Reactions of spinach ribulose-1,5-biphosphate carboxylase with tetranitromethane. Biochemistry 22:2697-2704.
3. Bugg, T.D.H., and C.T. Walsh. 1992. Intracellular steps of bacterial cell wall peptidoglycan biosynthesis: Enzymology, antibiotics, and antibiotic resistance. Nat. Prod. Rep. 9:199-215.
4. Duncan, K., and C.T. Walsh. 1988. ATP-dependent inactivation and slow binding inhibition of Salmonella typhimurium D-alanine:D-alanine ligase (ADP) by (aminoalkyl)phosphinate and phosphonate analogues of D-alanine. Biochemistry 27:3709-3714.
5. Fan, C., P.C. Moews, Y. Shi, C.T. Walsh, and J.R. Knox. 1995. A common fold for peptide synthetases cleaving ATP to ADP: Glutathione synthetase and D-alanine:D-alanine ligase of Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 92:1172-1176.
6. Hanau, S., F. Dallochio, and M. Rippa. 1993. Use of trinitrobenzenesulfonate for affinity labeling of lysine residues at phosphate-binding sites of some enzymes. Arch. Biochem. Biophys. 302:218-221.
7. Henriques, A.O., H. de Lencastre, and P.J. Piggot. 1992. A Bacillus subtilis morphogene cluster that includes spoVE is homologous to the mra region of Escherichia coli. Biochimie 74:735-748.
8. Ikeda, M., M. Wachi, F. Ishino, and M. Matsuhashi. 1990. Nucleotide sequence involving murD and an open reading frame ORF-Y spacing murF and ftsW in Escherichia coli. Nucl. Acids Res. 18:1058.
9. Ikeda, M., M. Wachi, H.K. Jung, F. Ishino, and M. Matsuhashi. 1990. Homology among MurC, MurD, MurE and MurF proteins in Escherichia coli and that between E. coli MurG and a possible MurG protein in Bacillus subtilis. J. Gen. Appl. Microbiol. 36:179-187.
10. Krishnaswamy, P.R., V. Pamiljans, and A. Meister. 1962. Studies on the mechanism of glutamine synthesis: Evidence for the formation of enzyme-bound activated glutamic acid. J. Biol. Chem. 237:2932-2940.
11. Lane, R.S., and E.E. Dekker. 1972. Oxidation of sulfhydryl groups of bovine liver 2-keto-4-hydroxyglutarate aldolase by tetranitromethane. Biochemistry 11:3295-3303.
12. Lanzetta, P.A., L.J. Alvarez, P.S. Reinach, and O.A. Candia. 1979. An improved assay for nanomole amounts of inorganic phosphate. Anal. Biochem. 100:95-97.
13. Mengin-Lecreulx, D., and J. van Heijenoort. 1990. Nucleotide sequence of the murD gene encoding the UDP-MurNAc-L-Ala-D-Glu synthetase of Escherichia coli. Nucl. Acids Res. 18:183.
14. Michaud, C., D. Blanot, B. Flouret, and J. van Heijenoort. 1987. Partial purification and specificity studies of the D-glutamate-adding and D-alanyl-D-alanine-adding enzymes from Escherichia coli K12. Eur. J. Biochem. 166:631-637.
15. Mullins, L.S., L.E. Zawadzke, C.T. Walsh, and F.M. Raushel. 1990. Kinetic evidence for the formation of D-alanyl phosphate in the mechanism of D-alanyl-D-alanine ligase. J. Biol. Chem. 265:8993-8998.
16. Nishimura, J.S., E.A. Dodd, and A. Meister. 1963. Evidence for an intermediate in the synthesis of γ-glutamyl-α-aminobutyryl-glycine by glutathione synthetase. J. Biol. Chem. 238:PC1179-PC1180.
17. Pratviel-Sosa, F., F. Acher, F. Trigalo, D. Blanot, R. Azerad, and J. van Heijenoort. 1994. Effect of various analogues of D-glutamic acid on the D-glutamate-adding enzyme from Escherichia coli. FEMS Microbiol. Lett. 115:223-228.
18. Pratviel-Sosa, F., D. Mengin-Lecreulx, and J. van Heijenoort. 1991. Over-production, purification and properties of the uridine diphosphate N-acetylmuramoyl-L-alanine:D-glutamate ligase from Escherichia coli. Eur. J. Biochem. 202:1169-1176.
19. Randerath, K., and E. Randerath. 1964. Ion-exchange chromatography of nucleotides on poly(ethyleneimine)-cellulose thin layers. J. Chromatogr. 16:111-125.
20. Riordan, J.F., and B.L. Vallee. 1972. Nitration with tetranitromethane. Methods Enzymol. 25:515-521.
21. Seddon, A.P., Y.K. Zhao, and A. Meister. 1989. Activation of glutamate by γ-glutamate kinase: Formation of γ-cis-cycloglutamyl phosphate, an analog of γ-glutamyl phosphate. J. Biol. Chem. 264:11326-11335.
22. Segel, I.H. 1975. Enzyme kinetics, p. 860. John Wiley, New York.
23. Tanner, M.E., S. Vaganay, J. van Heijenoort, and D. Blanot. 1996. Phosphinate inhibitors of the D-glutamic acid-adding enzyme of peptidoglycan synthesis. J. Org. Chem. 61:1756-1760.
24. Tsuda, Y., R.A. Stephani, and A. Meister. 1971. Direct evidence for the formation of an acyl phosphate by glutamine synthetase. Biochemistry 10:3186-3189.
25. van Heijenoort, J. 1994. Biosynthesis of the peptidoglycan unit, pp. 39-54. In J.M. Ghuysen and R. Hakenbeck (eds.), Bacterial cell wall. Elsevier Science B.V., Amsterdam.