-
1
-
-
7144250526
-
Molecular mechanisms of pancreatic beta-cell destruction in autoimmune diabetes: Potential targets for preventive therapy
-
Iwashashi I, Itoh N, Yamagata K, et al. Molecular mechanisms of pancreatic beta-cell destruction in autoimmune diabetes: potential targets for preventive therapy. Cytokines Cell Mol Ther 1998; 4: 45-51.
-
(1998)
Cytokines Cell Mol Ther
, vol.4
, pp. 45-51
-
-
Iwashashi, I.1
Itoh, N.2
Yamagata, K.3
-
2
-
-
0030030135
-
Elevated serum levels of macrophage-derived cytokines precede and accompany the onset of IDDM
-
Hussain MJ, Peakman M, Gallati H, et al. Elevated serum levels of macrophage-derived cytokines precede and accompany the onset of IDDM. Diabetologia 1996; 39: 60-69.
-
(1996)
Diabetologia
, vol.39
, pp. 60-69
-
-
Hussain, M.J.1
Peakman, M.2
Gallati, H.3
-
3
-
-
0032523104
-
Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus
-
Rabinovitch A, Suarez-Pinzon WL. Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus. Biochem Pharmacol 1998; 55: 1139-1149.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1139-1149
-
-
Rabinovitch, A.1
Suarez-Pinzon, W.L.2
-
4
-
-
0029817047
-
The role of interleukin-1 in the pathogenesis of IDDM
-
Mandrup-Poulsen T. The role of interleukin-1 in the pathogenesis of IDDM. Diabetologia 1996; 39: 1005-1029.
-
(1996)
Diabetologia
, vol.39
, pp. 1005-1029
-
-
Mandrup-Poulsen, T.1
-
5
-
-
0038755593
-
Enhanced lipid peroxidation and platelet activation in the early phase of type 1 diabetes mellitus: Role of interleukin-6 and disease duration
-
Davi G, Chiarelli F, Santilli F, et al. Enhanced lipid peroxidation and platelet activation in the early phase of type 1 diabetes mellitus: role of interleukin-6 and disease duration. Circulation 2003; 107: 3199-3203.
-
(2003)
Circulation
, vol.107
, pp. 3199-3203
-
-
Davi, G.1
Chiarelli, F.2
Santilli, F.3
-
6
-
-
12144290761
-
Differential effects of interleukin-6 and-10 on skeletal muscle and liver insulin action in vivo
-
Kim HJ, Higashimori T, Park SY, et al. Differential effects of interleukin-6 and-10 on skeletal muscle and liver insulin action in vivo. Diabetes 2004; 53: 1060-1067.
-
(2004)
Diabetes
, vol.53
, pp. 1060-1067
-
-
Kim, H.J.1
Higashimori, T.2
Park, S.Y.3
-
7
-
-
0035908632
-
C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
-
Pradhan AD, Manson JE, Rifai N, et al. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA 2001; 286: 327-334.
-
(2001)
JAMA
, vol.286
, pp. 327-334
-
-
Pradhan, A.D.1
Manson, J.E.2
Rifai, N.3
-
8
-
-
0027459878
-
Adipose expression of tumor necrosis factor-α: Direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargil NS, Spiegelman BM. Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance. Science 1993; 259: 87-91.
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargil, N.S.2
Spiegelman, B.M.3
-
9
-
-
11244258501
-
Popliteal lymph node responses to acetone and ethanol differ from those induced by streptozotocin
-
Choquet-Kastylevsky G, Descotes J. Popliteal lymph node responses to acetone and ethanol differ from those induced by streptozotocin. Arch Toxicol 2004; 78: 649-654.
-
(2004)
Arch Toxicol
, vol.78
, pp. 649-654
-
-
Choquet-Kastylevsky, G.1
Descotes, J.2
-
10
-
-
0018838435
-
Protection against streptozotocin-induced diabetes by superoxide dismutase
-
Robbins MJ, Sharp RA, Slonim AE, et al. Protection against streptozotocin-induced diabetes by superoxide dismutase. Diabetologia 1980; 18: 55-58.
-
(1980)
Diabetologia
, vol.18
, pp. 55-58
-
-
Robbins, M.J.1
Sharp, R.A.2
Slonim, A.E.3
-
11
-
-
0034044814
-
The role of nitric oxide in the development of streptozotocin-induced diabetes mellitus: Experimental and clinical implications
-
Haluzik M, Nedvidkova J. The role of nitric oxide in the development of streptozotocin-induced diabetes mellitus: experimental and clinical implications. Physiol Res 2000; 49: (Suppl. 1): S37-S42.
-
(2000)
Physiol Res
, vol.49
, Issue.SUPPL. 1
-
-
Haluzik, M.1
Nedvidkova, J.2
-
13
-
-
0031757110
-
Heat shock inhibits cytokine-induced nitric oxide synthase expression by rat and human islets
-
Scarim AL, Heitmeier MR, Corbett JA. Heat shock inhibits cytokine-induced nitric oxide synthase expression by rat and human islets. Endocrinology 1998; 139: 5050-5057.
-
(1998)
Endocrinology
, vol.139
, pp. 5050-5057
-
-
Scarim, A.L.1
Heitmeier, M.R.2
Corbett, J.A.3
-
14
-
-
0035208918
-
Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells
-
Lakey JR, Suarez-Pinzon WL, Strynadka K, et al. Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells. Lab Invest 2001; 81: 1683-1692.
-
(2001)
Lab Invest
, vol.81
, pp. 1683-1692
-
-
Lakey, J.R.1
Suarez-Pinzon, W.L.2
Strynadka, K.3
-
15
-
-
0036244508
-
Nitric oxide and peroxynitrite interactions with mitochondria
-
Radi R, Cassina A, Hodara R. Nitric oxide and peroxynitrite interactions with mitochondria. Biol Chem 2002; 383: 401-409.
-
(2002)
Biol Chem
, vol.383
, pp. 401-409
-
-
Radi, R.1
Cassina, A.2
Hodara, R.3
-
16
-
-
0028900805
-
Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase
-
Corbett JA, McDaniel ML. Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase. J Exper Med 1995; 181: 559-568.
-
(1995)
J Exper Med
, vol.181
, pp. 559-568
-
-
Corbett, J.A.1
McDaniel, M.L.2
-
17
-
-
0030923812
-
Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islets cells
-
Delaney CA, Pavlovic D, Hoorens A, et al. Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islets cells. Endocrinology 1997; 138: 2610-2614.
-
(1997)
Endocrinology
, vol.138
, pp. 2610-2614
-
-
Delaney, C.A.1
Pavlovic, D.2
Hoorens, A.3
-
18
-
-
0033935559
-
K (ATP) channel openers protect rat islets against the toxic effect of streptozotocin
-
Kullin M, Li Z, Hansen JB, et al. K (ATP) channel openers protect rat islets against the toxic effect of streptozotocin. Diabetes 2000; 49: 1131-1136.
-
(2000)
Diabetes
, vol.49
, pp. 1131-1136
-
-
Kullin, M.1
Li, Z.2
Hansen, J.B.3
-
19
-
-
0024539819
-
Studies on the mechanisms causing inhibition of insulin secretion in rat pancreatic islets exposed to human interleukin-1β indicate a perturbation in the mitochondrial function
-
Sandler S, Bendtzen K, Borg LAH, et al. Studies on the mechanisms causing inhibition of insulin secretion in rat pancreatic islets exposed to human interleukin-1β indicate a perturbation in the mitochondrial function. Endocrinology 1989; 124: 1492-1501.
-
(1989)
Endocrinology
, vol.124
, pp. 1492-1501
-
-
Sandler, S.1
Bendtzen, K.2
Borg, L.A.H.3
-
20
-
-
12344270191
-
High glucose potentiates cytokine- and streptozotocin-induced apoptosis of rat islet cells: Effect on apoptosis-related genes
-
Mellado-Gil JM, Aguilar-Diosdado M. High glucose potentiates cytokine- and streptozotocin-induced apoptosis of rat islet cells: effect on apoptosis-related genes. J Endocrinology 2004; 183: 155-162.
-
(2004)
J Endocrinology
, vol.183
, pp. 155-162
-
-
Mellado-Gil, J.M.1
Aguilar-Diosdado, M.2
-
21
-
-
0036738398
-
Glucose-induced B cell production of IL-1β contributes to glucotoxicity in human pancreatic islets
-
Maedler K, Sergejeev P, Ris F, et al. Glucose-induced B cell production of IL-1β contributes to glucotoxicity in human pancreatic islets. J Clin Invest 2002; 110: 851-860.
-
(2002)
J Clin Invest
, vol.110
, pp. 851-860
-
-
Maedler, K.1
Sergejeev, P.2
Ris, F.3
-
22
-
-
12144255424
-
Hyperglycemia induces monocytic release of interleukin-6 via induction of protein kinase C-α, and β
-
Devaraj S, Venugopal SK, Singh U, et al. Hyperglycemia induces monocytic release of interleukin-6 via induction of protein kinase C-α, and β. Diabetes 2005; 54: 85-91.
-
(2005)
Diabetes
, vol.54
, pp. 85-91
-
-
Devaraj, S.1
Venugopal, S.K.2
Singh, U.3
-
23
-
-
23044468612
-
Interleukin-6 depletion selectively improves hepatic insulin action in obesity
-
Klover PJ, Clementi AH, Mooney RA. Interleukin-6 depletion selectively improves hepatic insulin action in obesity. Endocrinology 2005; 146: 3417-3427.
-
(2005)
Endocrinology
, vol.146
, pp. 3417-3427
-
-
Klover, P.J.1
Clementi, A.H.2
Mooney, R.A.3
-
24
-
-
0030782520
-
Dose-dependent effects of recombinant human interleukin-6 on glucose regulation
-
Tsigos C, Papanicolaou DA, Kyrou I, et al. Dose-dependent effects of recombinant human interleukin-6 on glucose regulation. J Clin Endocrinol Metabolism 1997; 82: 4167-4170.
-
(1997)
J Clin Endocrinol Metabolism
, vol.82
, pp. 4167-4170
-
-
Tsigos, C.1
Papanicolaou, D.A.2
Kyrou, I.3
-
25
-
-
0033921236
-
Amlodipine inhibits the production of cytokines induced by ouabain
-
Matsumori A, Ono K, Nishio R, et al. Amlodipine inhibits the production of cytokines induced by ouabain. Cytokine 2000; 12: 294-297.
-
(2000)
Cytokine
, vol.12
, pp. 294-297
-
-
Matsumori, A.1
Ono, K.2
Nishio, R.3
-
26
-
-
0037783277
-
Beneficial effects of low-dose benidipine in acute autoimmune myocarditis: Suppressive effects on inflammatory cytokines inducible nitric oxide synthase
-
Yuan Z, Kishimoto C, Shioji K. Beneficial effects of low-dose benidipine in acute autoimmune myocarditis: suppressive effects on inflammatory cytokines inducible nitric oxide synthase. Cir J 2003; 67: 545-550.
-
(2003)
Cir J
, vol.67
, pp. 545-550
-
-
Yuan, Z.1
Kishimoto, C.2
Shioji, K.3
-
27
-
-
0345040856
-
Felodipine inhibits free-radical production by cytokines and glucose in human smooth muscle cells
-
Hishikawa K, Luscher TF. Felodipine inhibits free-radical production by cytokines and glucose in human smooth muscle cells. Hypertension 1998; 32: 1011-1015.
-
(1998)
Hypertension
, vol.32
, pp. 1011-1015
-
-
Hishikawa, K.1
Luscher, T.F.2
-
28
-
-
0037177366
-
Antiinflammatory effects of cerebrocrast in a model of rat paw edema and on mononuclear THP-1 cells
-
Klegeris A, Liutkevicius E, Mikalauskiene G, et al. Antiinflammatory effects of cerebrocrast in a model of rat paw edema and on mononuclear THP-1 cells. Eur J Pharmacol 2002; 441: 203-208.
-
(2002)
Eur J Pharmacol
, vol.441
, pp. 203-208
-
-
Klegeris, A.1
Liutkevicius, E.2
Mikalauskiene, G.3
-
29
-
-
0033030859
-
Effect of cerebrocrast on the lymphocyte blast transformation activity in normal and streptozotocin- induced diabetic rats
-
Briede J, Daija D, Stivrina M, et al. Effect of cerebrocrast on the lymphocyte blast transformation activity in normal and streptozotocin- induced diabetic rats. Cell Biochem Funct 1999; 17: 89-96.
-
(1999)
Cell Biochem Funct
, vol.17
, pp. 89-96
-
-
Briede, J.1
Daija, D.2
Stivrina, M.3
-
30
-
-
0034644766
-
Nifedipine inhibits activation of transcription factor NF-kappa B
-
Matsumori A, Nunokawa Y, Sasayama S. Nifedipine inhibits activation of transcription factor NF-kappa B. Life Sci 2000; 67: 2655-2661.
-
(2000)
Life Sci
, vol.67
, pp. 2655-2661
-
-
Matsumori, A.1
Nunokawa, Y.2
Sasayama, S.3
-
31
-
-
0018912679
-
On the relation of glucose and insulin secretion in the fasting state
-
Joost HG, Beckmann J. On the relation of glucose and insulin secretion in the fasting state. Metabolism 1980; 29(1): 23-27.
-
(1980)
Metabolism
, vol.29
, Issue.1
, pp. 23-27
-
-
Joost, H.G.1
Beckmann, J.2
-
32
-
-
0028120345
-
Reduced levels of messenger ribonucleic acid for calcium channel, glucose transporter-2, and glucokinase are associated with alterations in insulin secretion in fasted rats
-
Iwashima Y, Kondoh-Abiko A, Seino S, et al. Reduced levels of messenger ribonucleic acid for calcium channel, glucose transporter-2, and glucokinase are associated with alterations in insulin secretion in fasted rats. Endocrinology 1994; 135: 1010-1017.
-
(1994)
Endocrinology
, vol.135
, pp. 1010-1017
-
-
Iwashima, Y.1
Kondoh-Abiko, A.2
Seino, S.3
-
33
-
-
0034863625
-
Sustained hyperglycemia and insulin resistance induced by dietary restriction
-
Maeda T, Sakita R, Kaihatsu T, et al. Sustained hyperglycemia and insulin resistance induced by dietary restriction. Biol Pharm Bull 2001; 24: 950-953.
-
(2001)
Biol Pharm Bull
, vol.24
, pp. 950-953
-
-
Maeda, T.1
Sakita, R.2
Kaihatsu, T.3
-
34
-
-
0030991979
-
A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6-phosphatase gene transcription by insulin
-
Streeper RS, Svitek CA, Chapman SC. et al. A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6-phosphatase gene transcription by insulin. J Biol Chem 1997; 272: 11698-11701.
-
(1997)
J Biol Chem
, vol.272
, pp. 11698-11701
-
-
Streeper, R.S.1
Svitek, C.A.2
Chapman, S.C.3
-
35
-
-
0028287877
-
Isolation of a cDNA for the catalytic subunit of rat liver glucose-6-phosphatase: Regulation of gene expression in FAO hepatoma cells by insulin, dexamethasone and cAMP
-
Lange AJ, Argaud D, el-Maghrabi MR, et al. Isolation of a cDNA for the catalytic subunit of rat liver glucose-6-phosphatase: regulation of gene expression in FAO hepatoma cells by insulin, dexamethasone and cAMP Biochem Biophys Res Commun 1994; 201: 302-309.
-
(1994)
Biochem Biophys Res Commun
, vol.201
, pp. 302-309
-
-
Lange, A.J.1
Argaud, D.2
el-Maghrabi, M.R.3
-
36
-
-
0033034752
-
Effect of some 1,4-dihydropyridine Ca antagonists on the blast transformation of rat spleen lymphocytes
-
Briede J, Daija D, Bisenieks E, et al. Effect of some 1,4-dihydropyridine Ca antagonists on the blast transformation of rat spleen lymphocytes. Cell Biochem Funct 1999; 17: 97-105.
-
(1999)
Cell Biochem Funct
, vol.17
, pp. 97-105
-
-
Briede, J.1
Daija, D.2
Bisenieks, E.3
-
37
-
-
3142594179
-
Effect of new and known 1,4-dihydropiridine derivatives on blood glucose levels in normal and streptozotocin-induced diabetic rats
-
Briede J, Stivriņa M, Stoldere Dz, et al. Effect of new and known 1,4-dihydropiridine derivatives on blood glucose levels in normal and streptozotocin-induced diabetic rats. Cell Biochem Funct 2004; 22: 219-224.
-
(2004)
Cell Biochem Funct
, vol.22
, pp. 219-224
-
-
Briede, J.1
Stivriņa, M.2
Stoldere, D.3
-
38
-
-
0025887910
-
Interleukin-1β enhances corticosterone secretion by acting directly on the rat adrenal gland
-
Andreis PG, Neri G, Belloni AS, et al. Interleukin-1β enhances corticosterone secretion by acting directly on the rat adrenal gland. Endocrinology 1991; 129: 53-57.
-
(1991)
Endocrinology
, vol.129
, pp. 53-57
-
-
Andreis, P.G.1
Neri, G.2
Belloni, A.S.3
-
39
-
-
0023676538
-
Interleukin-6 stimulates the secretion of adrenocorticotrophic hormone in conscious, free-moving rats
-
Naitoh Y, Fukata J, Tominaga T, et al. Interleukin-6 stimulates the secretion of adrenocorticotrophic hormone in conscious, free-moving rats. Biochem Biophys Res Commun 1988; 155: 1459-1463.
-
(1988)
Biochem Biophys Res Commun
, vol.155
, pp. 1459-1463
-
-
Naitoh, Y.1
Fukata, J.2
Tominaga, T.3
-
40
-
-
0022001193
-
Effect of in vitro corticosteroids on B cell activation, proliferation and differentiation
-
Cupps TR, Gerrard TL, Falkoff RJ, et al. Effect of in vitro corticosteroids on B cell activation, proliferation and differentiation. J Clin Invest 1985; 75: 754.
-
(1985)
J Clin Invest
, vol.75
, pp. 754
-
-
Cupps, T.R.1
Gerrard, T.L.2
Falkoff, R.J.3
-
41
-
-
0018664625
-
Glucocorticoid-induced inhibition of T cell growth factor production. I. The effect of mitogen-induced lymphocyte proliferation
-
Gillis S, Crabtree G, Smith K. Glucocorticoid-induced inhibition of T cell growth factor production. I. The effect of mitogen-induced lymphocyte proliferation. J Immunol 1979; 123: 1624.
-
(1979)
J Immunol
, vol.123
, pp. 1624
-
-
Gillis, S.1
Crabtree, G.2
Smith, K.3
-
42
-
-
0024802919
-
Contrasting effects of glucocorticoids on the capacity of T cells to produce growth factors interleukins-2 and interleukins-4
-
Daynes RA, Araneo BA. Contrasting effects of glucocorticoids on the capacity of T cells to produce growth factors interleukins-2 and interleukins-4. Eur J Immunol 1989; 19: 2319-2325.
-
(1989)
Eur J Immunol
, vol.19
, pp. 2319-2325
-
-
Daynes, R.A.1
Araneo, B.A.2
-
43
-
-
0026691655
-
IL-4 and IL-2 selectively rescue Th cell subsets from glucocorticoid-induced apoptosis
-
Zubiaga AM, Munoz E, Huber BT. IL-4 and IL-2 selectively rescue Th cell subsets from glucocorticoid-induced apoptosis. J Immunol 1992; 149: 107-112.
-
(1992)
J Immunol
, vol.149
, pp. 107-112
-
-
Zubiaga, A.M.1
Munoz, E.2
Huber, B.T.3
-
44
-
-
0026568337
-
Apoptosis in human thymocytes after treatment with glucocorticoids
-
Nieto MA, Gonzalez F, Gambon F, et al. Apoptosis in human thymocytes after treatment with glucocorticoids. Clin Exp Immunol 1992; 88: 341-344.
-
(1992)
Clin Exp Immunol
, vol.88
, pp. 341-344
-
-
Nieto, M.A.1
Gonzalez, F.2
Gambon, F.3
-
45
-
-
0031059756
-
Effects of glucocorticoid excess on the sensitivity of glucose transport and metabolism to insulin in rat skeletal muscle
-
Dimitriadis G, Leighton B, Parry-Billings M, et al. Effects of glucocorticoid excess on the sensitivity of glucose transport and metabolism to insulin in rat skeletal muscle. Biochem J 1997; 321: 707-712.
-
(1997)
Biochem J
, vol.321
, pp. 707-712
-
-
Dimitriadis, G.1
Leighton, B.2
Parry-Billings, M.3
-
46
-
-
0026730101
-
Low dose streptozotocin-induced diabetes in mice: Reduced IL-2 production and modulation of streptozotocin-induced hyperglycemia by IL-2
-
Burkart V, Zielasek J, Kantwerk-Funke G, et al. Low dose streptozotocin-induced diabetes in mice: reduced IL-2 production and modulation of streptozotocin-induced hyperglycemia by IL-2. Int J Immunopharmacol 1992; 14: 1037-1044.
-
(1992)
Int J Immunopharmacol
, vol.14
, pp. 1037-1044
-
-
Burkart, V.1
Zielasek, J.2
Kantwerk-Funke, G.3
-
47
-
-
0025735437
-
Defective thymic T cell activation by concanavalin A and anti-CD3 in autoimmune non-obese diabetic mice. Evidence for thymic T cell anergy that correlates with the onset of insulitis
-
Zipris D, Lazarus AH, Crow AR, et al. Defective thymic T cell activation by concanavalin A and anti-CD3 in autoimmune non-obese diabetic mice. Evidence for thymic T cell anergy that correlates with the onset of insulitis. J Immunol 1991; 146: 3763-3771.
-
(1991)
J Immunol
, vol.146
, pp. 3763-3771
-
-
Zipris, D.1
Lazarus, A.H.2
Crow, A.R.3
-
48
-
-
14644405653
-
Differential regulation of human blood glucose level by interleukin-2 and-6
-
Harnish MJ, Lange T, Dimitrov S, et al. Differential regulation of human blood glucose level by interleukin-2 and-6. Exp Clin Endocrinol Diabetes 2005; 113: 43-48.
-
(2005)
Exp Clin Endocrinol Diabetes
, vol.113
, pp. 43-48
-
-
Harnish, M.J.1
Lange, T.2
Dimitrov, S.3
-
49
-
-
24844480446
-
Effect of cerebrocrast on glucose uptake in heart, brain of rats and on glucose transport in isolated human erythrocytes
-
Briede J, Stivrina M, Heidemanis K, et al. Effect of cerebrocrast on glucose uptake in heart, brain of rats and on glucose transport in isolated human erythrocytes. Fundamental & Clin Pharmacol 1999; 13(Suppl. 1): 170.
-
(1999)
Fundamental & Clin Pharmacol
, vol.13
, Issue.SUPPL. 1
, pp. 170
-
-
Briede, J.1
Stivrina, M.2
Heidemanis, K.3
-
50
-
-
0030667121
-
Evidence for the presence of type I IL-1 receptors on beta-cells of islets of Langerhans
-
Scarim AL, Arnush M, Hill JR, et al. Evidence for the presence of type I IL-1 receptors on beta-cells of islets of Langerhans. Biochim Biophys Acta 1997; 1361: 313-320.
-
(1997)
Biochim Biophys Acta
, vol.1361
, pp. 313-320
-
-
Scarim, A.L.1
Arnush, M.2
Hill, J.R.3
|