Anionic amino acids near the Pro-α-defensin N terminus mediate inhibition of bactericidal activity inmouse Pro-cryptdin-4

Journal of Biological Chemistry

Volumn 284, Issue 11, 2009, Pages 6826-6831

  Figueredo, Sharel M ^a   Weeks, Colby S ^a,c   Young, Steven K ^a   Ouellette, André J ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC AMINO ACIDS; ACIDIC RESIDUES; ADDITIVE EFFECTS; BACTERICIDAL ACTIVITY; CRYPTDINS; DEFENSIN; DEFENSINS; DIFFERENTIAL EFFECT; INHIBITORY MECHANISM; MATRIX METALLOPROTEINASE; MEMBRANE DISRUPTION; MEMBRANE PERMEABILIZATION; N-TERMINAL;

AMINATION; AMINO ACIDS; ESCHERICHIA COLI; MEMBRANES; ORGANIC ACIDS;

AMINES;

ALPHA DEFENSIN; ASPARAGINE; BACTERICIDAL PERMEABILITY INCREASING PROTEIN; CRYPTIDIN 4; GLUTAMIC ACID; GLYCINE; UNCLASSIFIED DRUG; AMINO ACID; CRYPTDIN 4, MOUSE; MATRILYSIN; PROTEIN PRECURSOR;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; ESCHERICHIA COLI; GENE CLUSTER; GENE DELETION; GENE MUTATION; INHIBITION KINETICS; MEMBRANE DAMAGE; MEMBRANE PERMEABILITY; MOUSE; NONHUMAN; POSITION EFFECT; PRIORITY JOURNAL; AMINO ACID SEQUENCE; ANIMAL; CELL MEMBRANE PERMEABILITY; CHEMISTRY; DRUG EFFECT; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PANETH CELL; PHYSIOLOGY;

ESCHERICHIA COLI;

ALPHA-DEFENSINS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACIDS, ACIDIC; ANIMALS; CELL MEMBRANE PERMEABILITY; ESCHERICHIA COLI; MATRIX METALLOPROTEINASE 7; MICE; PANETH CELLS; PROTEIN PRECURSORS;

EID: 65449140989     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807024200     Document Type: Article

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