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Volumn 9, Issue 3, 2009, Pages 306-317

New insight in LPS antagonist

Author keywords

Innate immunity; Lipid A; Lipopolysaccharide; Sepsis; Toll like receptor 4

Indexed keywords

6 [N (2 CHLORO 4 FLUOROPHENYL)SULFAMOYL] 1 CYCLOHEXENE 1 CARBOXYLIC ACID ETHYL ESTER; ANTIINFLAMMATORY AGENT; BACTERIUM LIPOPOLYSACCHARIDE; BESIFLOXACIN; CD200 ANTIGEN; CRX 526; CYP; LIPID A; LIPID A DERIVATIVE; LIPOPOLYSACCHARIDE; MOXIFLOXACIN; PROTEIN LP17; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TOLL LIKE RECEPTOR 4; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; UNCLASSIFIED DRUG; DRUG DERIVATIVE;

EID: 65349186058     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389557510909030306     Document Type: Review
Times cited : (56)

References (100)
  • 1
    • 0037180768 scopus 로고    scopus 로고
    • The immunopathogenesis of sepsis
    • Cohen, J. The immunopathogenesis of sepsis. Nature, 2002, 420, 885-91.
    • (2002) Nature , vol.420 , pp. 885-891
    • Cohen, J.1
  • 2
    • 0037451929 scopus 로고    scopus 로고
    • The epidemiology of sepsis in the United States from 1979 through 2000
    • Martin, G.S.; Mannino, D.M.; Eaton, S.; Moss, M. The epidemiology of sepsis in the United States from 1979 through 2000. N. Engl. J. Med., 2003, 348, 1546-54.
    • (2003) N. Engl. J. Med , vol.348 , pp. 1546-1554
    • Martin, G.S.1    Mannino, D.M.2    Eaton, S.3    Moss, M.4
  • 3
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
    • Angus, D.C.; Linde-Zwirble, W.T.; Lidicker, J.; Clermont, G.; Carcillo, J.; Pinsky M.R. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit. Care Med., 2001, 29, 1303-10.
    • (2001) Crit. Care Med , vol.29 , pp. 1303-1310
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3    Clermont, G.4    Carcillo, J.5    Pinsky, M.R.6
  • 5
    • 3242790926 scopus 로고    scopus 로고
    • Sepsis: Current status, future prospects
    • Marshall, J.C. Sepsis: current status, future prospects. Curr. Opin. Crit. Care, 2004, 10, 250-64.
    • (2004) Curr. Opin. Crit. Care , vol.10 , pp. 250-264
    • Marshall, J.C.1
  • 6
    • 0022462376 scopus 로고
    • Isolation of a lipopolysac-charide-binding acute phase reactant from rabbit serum
    • Tobias, P.S.; Soldau, K.; Ulevitch, R.J. Isolation of a lipopolysac-charide-binding acute phase reactant from rabbit serum. J. Exp. Med., 1986, 164, 777-93.
    • (1986) J. Exp. Med , vol.164 , pp. 777-793
    • Tobias, P.S.1    Soldau, K.2    Ulevitch, R.J.3
  • 7
    • 0024464813 scopus 로고
    • Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages
    • Wright, S.D.; Tobias, P.S.; Ulevitch, R.J.; Ramos, R.A. Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages. J. Exp. Med., 1989, 170, 1231-41.
    • (1989) J. Exp. Med , vol.170 , pp. 1231-1241
    • Wright, S.D.1    Tobias, P.S.2    Ulevitch, R.J.3    Ramos, R.A.4
  • 8
    • 0032519672 scopus 로고    scopus 로고
    • CD14-dependent internalization of bacterial lipopolysaccharide (LPS) is strongly influenced by LPS aggregation but not by cellular responses to LPS
    • Kitchens, R.L.; Munford, R.S. CD14-dependent internalization of bacterial lipopolysaccharide (LPS) is strongly influenced by LPS aggregation but not by cellular responses to LPS. J. Immunol., 1998, 160, 1920-8.
    • (1998) J. Immunol , vol.160 , pp. 1920-1928
    • Kitchens, R.L.1    Munford, R.S.2
  • 9
    • 0023687039 scopus 로고
    • The monocyte differentiation antigen, CD14, is anchored to the cell membrane by a phosphatidylinositol linkage
    • Haziot, A.; Chen, S.; Ferrero, E.; Low, M.G.; Silber, R.; Goyert, S.M. The monocyte differentiation antigen, CD14, is anchored to the cell membrane by a phosphatidylinositol linkage. J. Immunol., 1988, 141, 547-52.
    • (1988) J. Immunol , vol.141 , pp. 547-552
    • Haziot, A.1    Chen, S.2    Ferrero, E.3    Low, M.G.4    Silber, R.5    Goyert, S.M.6
  • 10
    • 0032738604 scopus 로고    scopus 로고
    • Role of CD14 in cellular recognition of bacterial lipopolysaccharides
    • Kitchens, R.L. Role of CD14 in cellular recognition of bacterial lipopolysaccharides. Chem. Immunol. 2000, 74, 61-82.
    • (2000) Chem. Immunol , vol.74 , pp. 61-82
    • Kitchens, R.L.1
  • 11
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov, R.; Preston-Hurlburt, P.; Janeway, C.A. Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature, 1997, 388, 394-7.
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 13
    • 0033574415 scopus 로고    scopus 로고
    • Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
    • Chow, J.C.; Young, D.W.; Golenbock, D.T.; Christ, W.J.; Gusovsky, F. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J. Biol. Chem., 1999, 274, 10689-92.
    • (1999) J. Biol. Chem , vol.274 , pp. 10689-10692
    • Chow, J.C.1    Young, D.W.2    Golenbock, D.T.3    Christ, W.J.4    Gusovsky, F.5
  • 14
    • 0034177888 scopus 로고    scopus 로고
    • Cutting edge: Cell surface expression and lipopolysaccharide signalling via the toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages
    • Akashi, S.; Shimazu, R.; Ogata, H.; Nagai, Y.; Takeda, K.; Kimoto, M.; Miyake, K. Cutting edge: cell surface expression and lipopolysaccharide signalling via the toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages. J. Immunol., 2000, 164, 3471-5.
    • (2000) J. Immunol , vol.164 , pp. 3471-3475
    • Akashi, S.1    Shimazu, R.2    Ogata, H.3    Nagai, Y.4    Takeda, K.5    Kimoto, M.6    Miyake, K.7
  • 15
    • 0033532629 scopus 로고    scopus 로고
    • MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
    • Shimazu, R.; Akashi, S.; Ogata, H.; Nagai, Y.; Fukudome, K.; Miyake, K.; Kimoto, M. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp.Med., 1999, 189, 1777-82.
    • (1999) J. Exp.Med , vol.189 , pp. 1777-1782
    • Shimazu, R.1    Akashi, S.2    Ogata, H.3    Nagai, Y.4    Fukudome, K.5    Miyake, K.6    Kimoto, M.7
  • 17
    • 0034617274 scopus 로고    scopus 로고
    • Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4. MD-2 is required for activation of mitogen-activated protein kinases and Elk-1
    • Yang, H.; Young, D.W.; Gusovsky, F.; Chow, J.C. Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4. MD-2 is required for activation of mitogen-activated protein kinases and Elk-1. J. Biol. Chem., 2000, 275, 20861-6.
    • (2000) J. Biol. Chem , vol.275 , pp. 20861-20866
    • Yang, H.1    Young, D.W.2    Gusovsky, F.3    Chow, J.C.4
  • 18
    • 0001575306 scopus 로고
    • Chemische erforschung von lipopolysacchariden gram-negativer bakterien.
    • Westphal, O. Luderitz, O. Chemische erforschung von lipopolysacchariden gram-negativer bakterien. Angew. Chem., 1954, 66, 407-417.
    • (1954) Angew. Chem , vol.66 , pp. 407-417
    • Westphal, O.1    Luderitz, O.2
  • 20
    • 0025188131 scopus 로고
    • Cytokine induction by lipopolysaccharide (LPS) corresponds to lethal toxicity and is inhibited by nontoxic Rhodobacter capsulatus LPS
    • Loppnow, H.; Libby, P.; Freudenberg, M.; Krauss, J.H.; Weckesser, J.; Mayer, H. Cytokine induction by lipopolysaccharide (LPS) corresponds to lethal toxicity and is inhibited by nontoxic Rhodobacter capsulatus LPS. Infect. Immun., 1990, 58, 3743-50.
    • (1990) Infect. Immun , vol.58 , pp. 3743-3750
    • Loppnow, H.1    Libby, P.2    Freudenberg, M.3    Krauss, J.H.4    Weckesser, J.5    Mayer, H.6
  • 21
    • 0026088437 scopus 로고
    • Lipid A-like molecules that antagonize the effects of endotoxins on human monocytes
    • Golenbock, D.T.;, Hampton, R.Y.; Qureshi, N.; Takayama, K.; Raetz, C.R. Lipid A-like molecules that antagonize the effects of endotoxins on human monocytes. J. Biol. Chem., 1991, 266, 19490-8.
    • (1991) J. Biol. Chem , vol.266 , pp. 19490-19498
    • Golenbock, D.T.1    Hampton, R.Y.2    Qureshi, N.3    Takayama, K.4    Raetz, C.R.5
  • 24
    • 33745041451 scopus 로고    scopus 로고
    • Cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression
    • Macagno, A.; Molteni, M; Rinaldi, A; Bertoni, F; Lanzavecchia, A.; Rossetti, C.; Sallusto, F. Cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression. J. Exp. Med., 2006, 203, 1481-92.
    • (2006) J. Exp. Med , vol.203 , pp. 1481-1492
    • Macagno, A.1    Molteni, M.2    Rinaldi, A.3    Bertoni, F.4    Lanzavecchia, A.5    Rossetti, C.6    Sallusto, F.7
  • 25
    • 0020045699 scopus 로고
    • Production and properties of cyanobacterial endotoxins
    • Keleti, G.; Sykora, J.L. 1982. Production and properties of cyanobacterial endotoxins. Appl. Environ. Microbiol., 1982, 43, 104-09.
    • (1982) Appl. Environ. Microbiol , vol.1982 , Issue.43 , pp. 104-109
    • Keleti, G.1    Sykora, J.L.2
  • 26
    • 46449131185 scopus 로고    scopus 로고
    • A cyanobacterial lipopolysaccharide antagonist inhibits cytokine production induced by Neisseria meningitidis in a human whole-blood model of septicemia
    • Jemmett, K.; Macagno, A.; Molteni, M.; Heckels, J.E.; Rossetti, C.; Christodoulides, M. A cyanobacterial lipopolysaccharide antagonist inhibits cytokine production induced by Neisseria meningitidis in a human whole-blood model of septicemia. Infect. Immun. 2008, 76, 3156-63.
    • (2008) Infect. Immun , vol.76 , pp. 3156-3163
    • Jemmett, K.1    Macagno, A.2    Molteni, M.3    Heckels, J.E.4    Rossetti, C.5    Christodoulides, M.6
  • 27
    • 46749148729 scopus 로고    scopus 로고
    • Cyanobacterial LPS antagonist (CyP)-A novel and efficient inhibitor of Escherichia coli LPS-induced cytokine response in the pig
    • Thorgersen, E.B.; Macagno, A.; Rossetti, C.; Mollnes, T.E. Cyanobacterial LPS antagonist (CyP)-A novel and efficient inhibitor of Escherichia coli LPS-induced cytokine response in the pig. Mol. Immunol., 2008, 45, 3553-57.
    • (2008) Mol. Immunol , vol.45 , pp. 3553-3557
    • Thorgersen, E.B.1    Macagno, A.2    Rossetti, C.3    Mollnes, T.E.4
  • 28
    • 0020535123 scopus 로고
    • Nontoxic lipopolysaccharide from Rhodopseudomonas sphaeroides ATCC 17023
    • Strittmatter, W.; Weckesser J., Salimath P.V.; Galanos C. 1983. Nontoxic lipopolysaccharide from Rhodopseudomonas sphaeroides ATCC 17023. J. Bacteriol., 1983, 155, 153-58.
    • (1983) J. Bacteriol , vol.1983 , Issue.155 , pp. 153-158
    • Strittmatter, W.1    Weckesser, J.2    Salimath, P.V.3    Galanos, C.4
  • 29
    • 0024391830 scopus 로고
    • 27-Hydroxyoctacosanoic acid is a major structural fatty acyl component of the LPS of Rhizobium trifolii ANU 843
    • Hollingsworth, R.I.; Carlson, R.W. 27-Hydroxyoctacosanoic acid is a major structural fatty acyl component of the LPS of Rhizobium trifolii ANU 843. J. Biol. Chem., 1989, 264, 9300-03.
    • (1989) J. Biol. Chem , vol.264 , pp. 9300-9303
    • Hollingsworth, R.I.1    Carlson, R.W.2
  • 30
    • 0001126593 scopus 로고    scopus 로고
    • Urbanik-Sypniewska, T.; Seydel, U.; Greck, M.; J. Weckesser, J.; Mayer, H. Chemical studies on the lipopolysaccharide of Rhizobium meliloti. Arch. Microbiol., 1989, 152, 527-32.
    • Urbanik-Sypniewska, T.; Seydel, U.; Greck, M.; J. Weckesser, J.; Mayer, H. Chemical studies on the lipopolysaccharide of Rhizobium meliloti. Arch. Microbiol., 1989, 152, 527-32.
  • 31
    • 0024343902 scopus 로고
    • Comparative analysis of cytokine induction in human vascular endothelial and smooth muscle cells
    • Loppnow, H.; Libby, P. Comparative analysis of cytokine induction in human vascular endothelial and smooth muscle cells. Lymphokine Res., 1989, 8, 293-99.
    • (1989) Lymphokine Res , vol.8 , pp. 293-299
    • Loppnow, H.1    Libby, P.2
  • 32
    • 0024515391 scopus 로고
    • Diphosphoryl lipid A from Rhodopseudomonas sphaeroides ATCC 17023 blocks induction of cachectin in macrophages by lipopolysaccharide
    • Takayama, K.; Qureshi, N.; Beutler, B.; Kirkland, T.N. Diphosphoryl lipid A from Rhodopseudomonas sphaeroides ATCC 17023 blocks induction of cachectin in macrophages by lipopolysaccharide. Infect. Immun., 1989, 57, 1336-38.
    • (1989) Infect. Immun , vol.57 , pp. 1336-1338
    • Takayama, K.1    Qureshi, N.2    Beutler, B.3    Kirkland, T.N.4
  • 33
    • 0025193891 scopus 로고
    • Lipid IVa inhibits synthesis and release of tumor necrosis factor induced by lipopolysaccharide in human blood ex vivo
    • Kovach, N.L.; Yee, E.; Munford, R.S.; Raetz, C.R.H.; Harlan, J.M. Lipid IVa inhibits synthesis and release of tumor necrosis factor induced by lipopolysaccharide in human blood ex vivo. J. Exp. Med., 1990, 172, 77-84.
    • (1990) J. Exp. Med , vol.172 , pp. 77-84
    • Kovach, N.L.1    Yee, E.2    Munford, R.S.3    Raetz, C.R.H.4    Harlan, J.M.5
  • 34
    • 15944384911 scopus 로고    scopus 로고
    • Lipopolysaccharides from Helicobacter pylori can act as antagonists for Toll-like receptor 4
    • Lepper, P.M.; Triantafilou, M.; Schumann, C.; Schneider, E.M.; Triantafilou, K. Lipopolysaccharides from Helicobacter pylori can act as antagonists for Toll-like receptor 4. Cell. Microbiol., 2005, 7, 519-28.
    • (2005) Cell. Microbiol , vol.7 , pp. 519-528
    • Lepper, P.M.1    Triantafilou, M.2    Schumann, C.3    Schneider, E.M.4    Triantafilou, K.5
  • 36
    • 0034977290 scopus 로고    scopus 로고
    • Type I Helicobacter pylori lipopolysaccharide stimulates Toll-like receptor 4 and activates mitogen oxidase 1 in gastric pit cells
    • Kawahara, T.; Teshima, S.; Oka, A.; Sugiyama, T.; Kishi, K.; Rokutan, K. Type I Helicobacter pylori lipopolysaccharide stimulates Toll-like receptor 4 and activates mitogen oxidase 1 in gastric pit cells. Infect. Immun., 2001, 69, 4382-89.
    • (2001) Infect. Immun , vol.69 , pp. 4382-4389
    • Kawahara, T.1    Teshima, S.2    Oka, A.3    Sugiyama, T.4    Kishi, K.5    Rokutan, K.6
  • 37
    • 0042859750 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-κB activation and chemokine expression by epithelial cells
    • Smith, M.F.; Mitchell, A.; Li, G.; Ding, S.; Fitzmaurice, A.M.; Ryan, K. Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-κB activation and chemokine expression by epithelial cells. J. Biol. Chem., 2003, 278, 32552-560.
    • (2003) J. Biol. Chem , vol.278 , pp. 32552-32560
    • Smith, M.F.1    Mitchell, A.2    Li, G.3    Ding, S.4    Fitzmaurice, A.M.5    Ryan, K.6
  • 38
    • 0026580542 scopus 로고
    • Compositional analysis of Helicobacter pylori rough form lipopolysaccharides
    • Moran, A.P.; Helander, I.M.; Kosunen, T.U. Compositional analysis of Helicobacter pylori rough form lipopolysaccharides. J. Bacteriol., 1992, 174, 1370-77.
    • (1992) J. Bacteriol , vol.174 , pp. 1370-1377
    • Moran, A.P.1    Helander, I.M.2    Kosunen, T.U.3
  • 39
    • 0028945356 scopus 로고
    • Cell surface characteristics of Helicobacter pylori
    • Moran, A.P. Cell surface characteristics of Helicobacter pylori. FEMS Immunol. Med. Microbiol., 1995, 10, 271-80.
    • (1995) FEMS Immunol. Med. Microbiol , vol.10 , pp. 271-280
    • Moran, A.P.1
  • 40
    • 0026580542 scopus 로고
    • Compositional analysis of Helicobacter pylori rough form lipopolysaccharides
    • Moran, A.P.; Helander, I.M.; Kosunen, T.U. Compositional analysis of Helicobacter pylori rough form lipopolysaccharides. J. Bacteriol., 1992, 174, 1370-77.
    • (1992) J. Bacteriol , vol.174 , pp. 1370-1377
    • Moran, A.P.1    Helander, I.M.2    Kosunen, T.U.3
  • 41
    • 0030873605 scopus 로고    scopus 로고
    • Structural characterization of the lipid A component of Helicobacter pylori rough- and smooth-form lipopolysaccharides
    • Moran, A.P.; Lindner, B.; Walsh, E.J. Structural characterization of the lipid A component of Helicobacter pylori rough- and smooth-form lipopolysaccharides. J. Bacteriol., 1997, 179, 6453-63.
    • (1997) J. Bacteriol , vol.179 , pp. 6453-6463
    • Moran, A.P.1    Lindner, B.2    Walsh, E.J.3
  • 43
    • 0035115080 scopus 로고    scopus 로고
    • Signalling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages
    • Hirschfeld, M.; Weis, J.J.; Toshchakov, V.; Salkowski, C.A.; Cody, M.J.; Watts, D.C. Signalling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages. Infect. Immun., 2001, 69, 1477-82.
    • (2001) Infect. Immun , vol.69 , pp. 1477-1482
    • Hirschfeld, M.1    Weis, J.J.2    Toshchakov, V.3    Salkowski, C.A.4    Cody, M.J.5    Watts, D.C.6
  • 44
    • 0036137216 scopus 로고    scopus 로고
    • Lipopolysaccharides from periodontopathic bacteria Porphyromonas gingivalis and Capnocytophaga ochracea are antagonists for human toll-like receptor
    • Yoshimura, A.; Kaneko, T.; Kato, Y.; Golenbock, D.T.; Hara, Y. Lipopolysaccharides from periodontopathic bacteria Porphyromonas gingivalis and Capnocytophaga ochracea are antagonists for human toll-like receptor. Infect. Immun., 2002, 70, 218-25.
    • (2002) Infect. Immun , vol.70 , pp. 218-225
    • Yoshimura, A.1    Kaneko, T.2    Kato, Y.3    Golenbock, D.T.4    Hara, Y.5
  • 45
    • 0033198204 scopus 로고    scopus 로고
    • Hirschfeld, M.; Kirschning, C.J.; Schwandner, R.; Wesche, H.; Weis, J.H.; Wooten, R.M; Weis, J.J. Cutting edge: inflammatory signalling by Borrelia burgdorferi lipoproteins is mediated by Toll-like receptor 2. J. Immunol., 1999, 163, 2382-86.
    • Hirschfeld, M.; Kirschning, C.J.; Schwandner, R.; Wesche, H.; Weis, J.H.; Wooten, R.M; Weis, J.J. Cutting edge: inflammatory signalling by Borrelia burgdorferi lipoproteins is mediated by Toll-like receptor 2. J. Immunol., 1999, 163, 2382-86.
  • 46
    • 0028907147 scopus 로고
    • Structural study on the free lipid A isolated from lipopolysaccharide of Porphyromonas gingivalis
    • Kumada, H.; Haishima, Y.; Umemoto, T.; Tanamoto, K. Structural study on the free lipid A isolated from lipopolysaccharide of Porphyromonas gingivalis. J. Bacteriol., 1995, 177, 2098-2106.
    • (1995) J. Bacteriol , vol.177 , pp. 2098-2106
    • Kumada, H.1    Haishima, Y.2    Umemoto, T.3    Tanamoto, K.4
  • 47
    • 0027367583 scopus 로고
    • Chemical structure of lipid A from Porphyromonas (Bacteroides) gingivalis lipopolysaccharide
    • Ogawa, T. Chemical structure of lipid A from Porphyromonas (Bacteroides) gingivalis lipopolysaccharide. FEBS Lett., 1993, 332, 197-201.
    • (1993) FEBS Lett , vol.332 , pp. 197-201
    • Ogawa, T.1
  • 48
    • 0030014397 scopus 로고    scopus 로고
    • Differential induction of IL-1β and IL-6 production by the nontoxic lipid A from Porphyromonas gingivalis in comparison with synthetic Escherichia coli lipid A in human peripheral blood mononuclear cells
    • Ogawa, T.; Uchida, H. Differential induction of IL-1β and IL-6 production by the nontoxic lipid A from Porphyromonas gingivalis in comparison with synthetic Escherichia coli lipid A in human peripheral blood mononuclear cells. FEMS Immunol. Med. Microbiol., 1996, 14, 1-13.
    • (1996) FEMS Immunol. Med. Microbiol , vol.14 , pp. 1-13
    • Ogawa, T.1    Uchida, H.2
  • 49
    • 0034040212 scopus 로고    scopus 로고
    • Toll-like receptors confer responsiveness to lipopolysaccharide from Porphyromonas gingivalis in human gingival fibroblasts
    • Tabeta, K.; Yamazaki, K.; Akashi, S.; Miyake, K.; Kumada, H.; Umemoto, T.; Yoshie, H. Toll-like receptors confer responsiveness to lipopolysaccharide from Porphyromonas gingivalis in human gingival fibroblasts. Infect. Immun., 2000, 68, 3731-35.
    • (2000) Infect. Immun , vol.68 , pp. 3731-3735
    • Tabeta, K.1    Yamazaki, K.2    Akashi, S.3    Miyake, K.4    Kumada, H.5    Umemoto, T.6    Yoshie, H.7
  • 50
    • 0034647798 scopus 로고    scopus 로고
    • Toll-like receptor 4-mediated signal pathway induced by Porphyromonas gingivalis lipopolysaccharide in human gingival fibroblasts
    • Wang, P.L.; Azuma, Y.; Shinohara, M.; Ohura, K. Toll-like receptor 4-mediated signal pathway induced by Porphyromonas gingivalis lipopolysaccharide in human gingival fibroblasts. Biochem. Biophys. Res. Commun., 2000, 273, 1161-67.
    • (2000) Biochem. Biophys. Res. Commun , vol.273 , pp. 1161-1167
    • Wang, P.L.1    Azuma, Y.2    Shinohara, M.3    Ohura, K.4
  • 52
    • 38949165130 scopus 로고    scopus 로고
    • Peptides of CD200 modulate LPS-induced TNF-alpha induction and mortality in vivo
    • Gorczynski, R.; Boudakov, I.; Khatri, I. Peptides of CD200 modulate LPS-induced TNF-alpha induction and mortality in vivo. J. Surg. Res., 2008, 145, 87-96.
    • (2008) J. Surg. Res , vol.145 , pp. 87-96
    • Gorczynski, R.1    Boudakov, I.2    Khatri, I.3
  • 53
    • 33646460670 scopus 로고    scopus 로고
    • Identification of tyrosine residues crucial for CD200R-mediated inhibition of mast cell activation
    • Zhang, S.; Phillips, J.H. Identification of tyrosine residues crucial for CD200R-mediated inhibition of mast cell activation. J. Leukoc. Biol., 2006, 79, 363-68.
    • (2006) J. Leukoc. Biol , vol.79 , pp. 363-368
    • Zhang, S.1    Phillips, J.H.2
  • 54
    • 0035206952 scopus 로고    scopus 로고
    • CD200 immunoadhesin suppresses collagen-induced arthritis in mice
    • Gorczynski, R.M.; Chen, Z.Q.; Yu, K.; Hu, J. CD200 immunoadhesin suppresses collagen-induced arthritis in mice. Clin. Immunol., 2001, 101, 328-34.
    • (2001) Clin. Immunol , vol.101 , pp. 328-334
    • Gorczynski, R.M.1    Chen, Z.Q.2    Yu, K.3    Hu, J.4
  • 55
    • 0032571844 scopus 로고    scopus 로고
    • Increased expression of the novel molecule Ox-2 is involved in prolongation of murine renal allograft survival
    • Gorczynski, R.M.; Chen, Z.; Fu, X.M. Increased expression of the novel molecule Ox-2 is involved in prolongation of murine renal allograft survival. Transplantation, 1998, 65, 1106-14.
    • (1998) Transplantation , vol.65 , pp. 1106-1114
    • Gorczynski, R.M.1    Chen, Z.2    Fu, X.M.3
  • 57
    • 0035149257 scopus 로고    scopus 로고
    • Control of glial immune function by neurons
    • Neumann, H. Control of glial immune function by neurons. Glia, 2001, 36, 191-99.
    • (2001) Glia , vol.36 , pp. 191-199
    • Neumann, H.1
  • 58
    • 0028325939 scopus 로고    scopus 로고
    • Immunomodulation of experimental autoimmune uveoretinitis: A model of tolerance induction with retinal antigens
    • Dick, A.D.; Cheng, Y.F.; Liversidge, J. Immunomodulation of experimental autoimmune uveoretinitis: A model of tolerance induction with retinal antigens. Eye, 2004, 8, 52-9.
    • (2004) Eye , vol.8 , pp. 52-59
    • Dick, A.D.1    Cheng, Y.F.2    Liversidge, J.3
  • 59
    • 10844288840 scopus 로고    scopus 로고
    • Enhanced tolerance to autoimmune uveitis in CD200-deficient mice correlates with a pronounced Th2 switch in response to antigen challenge
    • Taylor, N.; McConnachie, K.; Calder, C.; Dawson, R.; Dick, A.; Sedgwick, J.D.; Liversidge, J. Enhanced tolerance to autoimmune uveitis in CD200-deficient mice correlates with a pronounced Th2 switch in response to antigen challenge. J. Immunol., 2005, 174, 143-54.
    • (2005) J. Immunol , vol.174 , pp. 143-154
    • Taylor, N.1    McConnachie, K.2    Calder, C.3    Dawson, R.4    Dick, A.5    Sedgwick, J.D.6    Liversidge, J.7
  • 61
    • 3142748419 scopus 로고    scopus 로고
    • Human herpesvirus 8 K14 protein mimics CD200 in down-regulating macrophage activation through CD200 receptor
    • Foster-Cuevas, M.; Wright, G.J.; Puklavec, M.J.; Brown, M.H.; Barclay, A.N. Human herpesvirus 8 K14 protein mimics CD200 in down-regulating macrophage activation through CD200 receptor. J. Virol., 2004, 78, 7667-76.
    • (2004) J. Virol , vol.78 , pp. 7667-7676
    • Foster-Cuevas, M.1    Wright, G.J.2    Puklavec, M.J.3    Brown, M.H.4    Barclay, A.N.5
  • 62
    • 30644468833 scopus 로고    scopus 로고
    • The etiology of sepsis: Turned inside out
    • Brunn, G.J.; Platt, J.L. The etiology of sepsis: Turned inside out. Trends Mol. Med., 2006, 12, 10-6.
    • (2006) Trends Mol. Med , vol.12 , pp. 10-16
    • Brunn, G.J.1    Platt, J.L.2
  • 63
    • 3242658383 scopus 로고    scopus 로고
    • The CD200 and CD200 receptor cell surface proteins interact through their N-terminal immunoglobulin-like domains
    • Hatherley, D.; Barclay, A.N. The CD200 and CD200 receptor cell surface proteins interact through their N-terminal immunoglobulin-like domains. Eur. J. Immunol., 2004, 34, 1688-94.
    • (2004) Eur. J. Immunol , vol.34 , pp. 1688-1694
    • Hatherley, D.1    Barclay, A.N.2
  • 64
    • 0034657890 scopus 로고    scopus 로고
    • Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes
    • Bouchon, A.; Dietrich, J.; Colonna, M. Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. J. Immunol., 2000, 164, 4991-95.
    • (2000) J. Immunol , vol.164 , pp. 4991-4995
    • Bouchon, A.1    Dietrich, J.2    Colonna, M.3
  • 65
    • 0037805700 scopus 로고    scopus 로고
    • TREMs in the immune system and beyond
    • Colonna, M. TREMs in the immune system and beyond. Nat. Rev. Immunol., 2003, 3, 445-53.
    • (2003) Nat. Rev. Immunol , vol.3 , pp. 445-453
    • Colonna, M.1
  • 66
    • 0035953547 scopus 로고    scopus 로고
    • TREM-1 amplifies inflammation and is a crucial mediator of septic shock
    • Bouchon, A.; Facchetti, F.; Weigand, M.A.; Colonna, M. TREM-1 amplifies inflammation and is a crucial mediator of septic shock. Nature, 2001, 410, 1103-07.
    • (2001) Nature , vol.410 , pp. 1103-1107
    • Bouchon, A.1    Facchetti, F.2    Weigand, M.A.3    Colonna, M.4
  • 67
    • 0346665750 scopus 로고    scopus 로고
    • A role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune response
    • Bleharski, J.R.; Kiessler, V.; Buonsanti, C.; Sieling, P.A.; Stenger, S.; Colonna, M.; Modlin, R.L. A role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune response. J. Immunol., 2003, 170, 3812-18.
    • (2003) J. Immunol , vol.170 , pp. 3812-3818
    • Bleharski, J.R.1    Kiessler, V.2    Buonsanti, C.3    Sieling, P.A.4    Stenger, S.5    Colonna, M.6    Modlin, R.L.7
  • 68
    • 10644237032 scopus 로고    scopus 로고
    • A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis
    • Gibot, S.; Kolopp-Sarda, M.N.; Bene, M.C.; Bollaert, P.E.; Lozniewski, A.; Mory, F.; Levy, B.; Faure, G.C. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis. J. Exp. Med., 2004, 200, 1419-26.
    • (2004) J. Exp. Med , vol.200 , pp. 1419-1426
    • Gibot, S.1    Kolopp-Sarda, M.N.2    Bene, M.C.3    Bollaert, P.E.4    Lozniewski, A.5    Mory, F.6    Levy, B.7    Faure, G.C.8
  • 69
    • 0344234282 scopus 로고    scopus 로고
    • Crystal structure of the human myeloid cell activating receptor TREM-1
    • Radaev, S.; Kattah, M.; Rostro, B.; Colonna, M.; Sun, P. Crystal structure of the human myeloid cell activating receptor TREM-1. Structure, 2003, 11, 1527-35.
    • (2003) Structure , vol.11 , pp. 1527-1535
    • Radaev, S.1    Kattah, M.2    Rostro, B.3    Colonna, M.4    Sun, P.5
  • 70
    • 0025054391 scopus 로고
    • Characterization in vitro of a human tumor necrosis factor binding protein. A soluble form of tumor necrosis factor receptor
    • Lantz, M.; Gullberg, U.; Nilsson, E. Characterization in vitro of a human tumor necrosis factor binding protein. A soluble form of tumor necrosis factor receptor. J. Clin. Invest., 1990, 86, 1396-01.
    • (1990) J. Clin. Invest , vol.86 , pp. 1396-1401
    • Lantz, M.1    Gullberg, U.2    Nilsson, E.3
  • 71
    • 0026741275 scopus 로고
    • Tumor necrosis soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor β in vitro and in vivo
    • van Zee, K.J.; Kohno, T.; Fischer, E. Tumor necrosis soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor β in vitro and in vivo. Proc. Natl. Acad. Sci. USA., 1992, 89, 4845-53.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4845-4853
    • van Zee, K.J.1    Kohno, T.2    Fischer, E.3
  • 72
    • 0025260779 scopus 로고
    • Regulation of tumor necrosis factor alpha transcription in macrophages. Involvement of four NFκB motifs and constitutive and inducible form of NFκB
    • Collart, M.A.; Baeuerle, P.; Vassalli, P. Regulation of tumor necrosis factor alpha transcription in macrophages. Involvement of four NFκB motifs and constitutive and inducible form of NFκB. Mol. Cell. Biol., 1990, 10, 1498-06.
    • (1990) Mol. Cell. Biol , vol.10 , pp. 1498-1506
    • Collart, M.A.1    Baeuerle, P.2    Vassalli, P.3
  • 73
    • 0025782658 scopus 로고
    • NFκB contacts DNA by a heterodimer of the p50 and p65 subunit
    • Urban, M.B.; Schreck, R.; Baeuerle, P.A. NFκB contacts DNA by a heterodimer of the p50 and p65 subunit. EMBO J., 1991, 10, 1817-25.
    • (1991) EMBO J , vol.10 , pp. 1817-1825
    • Urban, M.B.1    Schreck, R.2    Baeuerle, P.A.3
  • 74
    • 0031452476 scopus 로고    scopus 로고
    • Proinflammatory and anti-inflammatory cytokines as mediators in the pathogenesis of septic shock
    • Dinarello, C.A. Proinflammatory and anti-inflammatory cytokines as mediators in the pathogenesis of septic shock. Chest, 1997, 112, S321-S329.
    • (1997) Chest , vol.112
    • Dinarello, C.A.1
  • 76
    • 0037426726 scopus 로고    scopus 로고
    • The pathophysiology and treatment of sepsis
    • Hotchkiss, R.S.; Karl, I.E. The pathophysiology and treatment of sepsis. N. Engl. J. Med., 2003, 348, 138-50.
    • (2003) N. Engl. J. Med , vol.348 , pp. 138-150
    • Hotchkiss, R.S.1    Karl, I.E.2
  • 78
    • 28544447821 scopus 로고    scopus 로고
    • Discovery of novel and potent small-molecule inhibitors of NO and cytokine production as antisepsis agents: Synthesis and biological activity of alkyl 6-(N-substituted sulfamoyl) cyclohex-1-ene-1-carboxylate
    • Yamada, M.; Ichikawa, T.; Ii, M.; Sunamoto, M.; Itoh, K.; Tamura, N.; Kitazaki, T. Discovery of novel and potent small-molecule inhibitors of NO and cytokine production as antisepsis agents: synthesis and biological activity of alkyl 6-(N-substituted sulfamoyl) cyclohex-1-ene-1-carboxylate. J. Med. Chem., 2005, 48, 7457-67.
    • (2005) J. Med. Chem , vol.48 , pp. 7457-7467
    • Yamada, M.1    Ichikawa, T.2    Ii, M.3    Sunamoto, M.4    Itoh, K.5    Tamura, N.6    Kitazaki, T.7
  • 79
    • 34548496023 scopus 로고    scopus 로고
    • Therapeutic effects of TAK-242, a novel selective Toll-like receptor 4 signal transduction inhibitor, in mouse endotoxin shock model
    • Sha, T.; Sunamoto, M.; Kitazaki, T.; Sato, J.; Ii, M.; Iizawa, Y. Therapeutic effects of TAK-242, a novel selective Toll-like receptor 4 signal transduction inhibitor, in mouse endotoxin shock model. Eur. J. Pharmacol., 2007, 571, 231-39.
    • (2007) Eur. J. Pharmacol , vol.571 , pp. 231-239
    • Sha, T.1    Sunamoto, M.2    Kitazaki, T.3    Sato, J.4    Ii, M.5    Iizawa, Y.6
  • 80
    • 33645097021 scopus 로고    scopus 로고
    • A novel cyclohexene derivative, TAK-242, selectively inhibits Toll-like receptor 4-mediated cytokine production through suppression of intracellular signalling
    • Ii, M.; Matsunaga, N.; Hazeki, K.; Nakamura, K.; Takashima, K.; Seya, T.; Hazeki, O.; Kitazaki, T.; Iizawa, Y. A novel cyclohexene derivative, TAK-242, selectively inhibits Toll-like receptor 4-mediated cytokine production through suppression of intracellular signalling. Mol. Pharmacol., 2006, 69, 1288-95.
    • (2006) Mol. Pharmacol , vol.69 , pp. 1288-1295
    • Ii, M.1    Matsunaga, N.2    Hazeki, K.3    Nakamura, K.4    Takashima, K.5    Seya, T.6    Hazeki, O.7    Kitazaki, T.8    Iizawa, Y.9
  • 83
    • 0037114185 scopus 로고    scopus 로고
    • A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signalling
    • Yamamoto, M.; Sato, S.; Mori, K.; Hoshino, K.; Takeuchi, O.; Takeda, K.; Akira, S. A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signalling. J. Immunol., 2002, 169, 6668-72.
    • (2002) J. Immunol , vol.169 , pp. 6668-6672
    • Yamamoto, M.1    Sato, S.2    Mori, K.3    Hoshino, K.4    Takeuchi, O.5    Takeda, K.6    Akira, S.7
  • 88
    • 37549031303 scopus 로고    scopus 로고
    • Zhang, J.Z.; Ward, K.W. Besifloxacin, a novel fluoroquinolone antimicrobial agent, exhibits potent inhibition of pro-inflammatory cytokines in human THP-1 monocytes. J. Antimicrob. Chemother., 2008, 61, 111-16.
    • Zhang, J.Z.; Ward, K.W. Besifloxacin, a novel fluoroquinolone antimicrobial agent, exhibits potent inhibition of pro-inflammatory cytokines in human THP-1 monocytes. J. Antimicrob. Chemother., 2008, 61, 111-16.
  • 89
    • 2542428509 scopus 로고    scopus 로고
    • Anti-inflammatory effects of moxifloxacin on activated human monocytic cells: Inhibition of NF-κB and mitogen-activated protein kinase activation and of synthesis of proinflammatory cytokines
    • Weiss, T; Shalit, I; Blau, H; Werber, S; Halperin, D; Levitov, A; Fabian, I. Anti-inflammatory effects of moxifloxacin on activated human monocytic cells: inhibition of NF-κB and mitogen-activated protein kinase activation and of synthesis of proinflammatory cytokines. Antimicrob. Agents Chemother., 2004, 48, 1974-82.
    • (2004) Antimicrob. Agents Chemother , vol.48 , pp. 1974-1982
    • Weiss, T.1    Shalit, I.2    Blau, H.3    Werber, S.4    Halperin, D.5    Levitov, A.6    Fabian, I.7
  • 90
    • 54049137982 scopus 로고    scopus 로고
    • Yang, C.S.; Ko, S.R.; Cho, B.G.; Shin, D.M.; Yuk, J.M.; Li, S.; Kim, J.M.; Evans, R.M.; Jung, J.S.; Song, D.K.; Jo, E.K. The Ginsenoside Metabolite Compound K, a Novel Agonist of Glucocorticoid Receptor, Induces Tolerance to Endotoxin-induced Lethal Shock. J. Cell. Mol. Med., 2007, Postprint;10.1111/ j.1582-4934.2007.00181.x
    • Yang, C.S.; Ko, S.R.; Cho, B.G.; Shin, D.M.; Yuk, J.M.; Li, S.; Kim, J.M.; Evans, R.M.; Jung, J.S.; Song, D.K.; Jo, E.K. The Ginsenoside Metabolite Compound K, a Novel Agonist of Glucocorticoid Receptor, Induces Tolerance to Endotoxin-induced Lethal Shock. J. Cell. Mol. Med., 2007, "Postprint";10.1111/ j.1582-4934.2007.00181.x
  • 92
    • 0041324898 scopus 로고    scopus 로고
    • The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: Molecular mechanisms for gene repression
    • De Bosscher, K.; Vanden Berghe, W.; Haegeman, G. The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression. Endocr. Rev., 2003, 24, 488-522.
    • (2003) Endocr. Rev , vol.24 , pp. 488-522
    • De Bosscher, K.1    Vanden Berghe, W.2    Haegeman, G.3
  • 97
    • 85036842795 scopus 로고    scopus 로고
    • http://www.ClinicalTrials.gov
  • 98
    • 0028302526 scopus 로고
    • Gram-negative bacterial sepsis and sepsis syndrome
    • Dunn, D.L. Gram-negative bacterial sepsis and sepsis syndrome. Surg. Clin. North. Am., 1994, 74, 621-35.
    • (1994) Surg. Clin. North. Am , vol.74 , pp. 621-635
    • Dunn, D.L.1
  • 99
    • 1342324768 scopus 로고    scopus 로고
    • Cutting edge: Activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma
    • Redecke, V., Häcker, H., Datta, S.K., Fermin, A., Pitha, P.M., Broide, D.H., Raz, E. Cutting edge: activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma. J. Immunol., 2004, 172, 2739-2743.
    • (2004) J. Immunol , vol.172 , pp. 2739-2743
    • Redecke, V.1    Häcker, H.2    Datta, S.K.3    Fermin, A.4    Pitha, P.M.5    Broide, D.H.6    Raz, E.7
  • 100
    • 0142244180 scopus 로고    scopus 로고
    • A new model for inflammation-induced preterm birth: The role of platelet-activating factor and Toll-like receptor-4
    • Elovitz, M.A., Wang, Z., Chien, E.K., Rychlik, D.F., Phillippe, M. A new model for inflammation-induced preterm birth: the role of platelet-activating factor and Toll-like receptor-4. Am. J. Pathol., 2003, 163, 2103-11.
    • (2003) Am. J. Pathol , vol.163 , pp. 2103-2111
    • Elovitz, M.A.1    Wang, Z.2    Chien, E.K.3    Rychlik, D.F.4    Phillippe, M.5


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