An A3-subtype adenosine receptor is highly expressed in rat vascular smooth muscle cells: Its role in attenuating adenosine-induced increase in cAMP

Microvascular Research

Volumn 54, Issue 3, 1997, Pages 243-252

  Zhao, Zhihui ^a   Francis, Cynthia E ^a   Ravid, Katya ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine; Adenosine receptors; Vascular smooth muscle

Indexed keywords

6 N (3 IODOBENZYL)ADENOSINE 5' N METHYLCARBOXAMIDE; 6 N CYCLOPENTYLADENOSINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A3 RECEPTOR; ADENOSINE DERIVATIVE; ADENYLATE CYCLASE; ANTISENSE OLIGONUCLEOTIDE; COMPLEMENTARY DNA; CYCLIC AMP; FORSKOLIN; MESSENGER RNA; PHENYLISOPROPYLADENOSINE;

ADOLESCENT; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; NEWBORN; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTO ONCOGENE; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALIA;

EID: 0031951593     PISSN: 00262862     EISSN: None     Source Type: Journal    
DOI: 10.1006/mvre.1997.2044     Document Type: Article

References (32)

1. 1. Belardinelli, L., Linden, J., and Berne, R. M. (1989). The cardiac effects of adenosine. Prog. Cardiovasc. Dis. 32, 73-97.
2. 2. Biaggioni, I., Olafsson, B., Robertson, R. M., Hollister, A. S., and Robertson, D. (1987). Cardiovascular and respiratory effects of adenosine in conscious man: Evidence for chemoreceptor activation. Circ. Res. 61, 779-786.
3. 3. Jonzon, B., Nilsson, J., and Fredholm, B. B. (1985). Adenosine receptor-mediated changes in cyclic AMP production and DNA synthesis in cultured arterial smooth muscle cells. J. Cell. Physiol. 124, 451-456.
4. 4. Ribeiro, J. A., and Sebastiao, A. M. (1986). Adenosine receptors and calcium: Basis for proposing a third (A3) adenosine receptor. Prog. Neurobiol. 26, 179-209.
5. 5. Querol-Ferrer, V., Hultgardth-Nilsson, A., Ringertz, N. R., Nilsson, J., and Jonzon, B. (1992). Adenosine receptors, cAMP accumulation, and DNA-synthesis in aortic smooth muscle cell culture of adult and neonatal rats. J. Cell. Phys. 151, 555-560.
6. 6. Stiles, G. L. (1992). Adenosine receptors. J. Biol. Chem. 267, 6451-6454.
7. 7. Reppert, S. M., Weaver, D. R., Stehle, J. H., and Rivkees, S. A. (1991). Molecular cloning and characterization of a rat A1-adenosine receptor that is widely expressed in brain and spinal cord. Mol. Endocrinol. 5, 1037-1048.
8. 8. Fink, J. S., Weaver, D. R., Rivkees, S. A., Paterfreund, R. A., Pollak, A. E., Adler, E. M., and Reppert, S. M. (1992). Molecular cloning of the rat A2 adenosine receptor: Selective co-expression with D2 dopamine receptors in rat striatum. Mol. Brain. Res. 14, 186-195.
9. 9. Stehle, J. H., Rivkees, S. A., Lee, J. J., Weaver, D. R., Deeds, J. D., and Reppert, S. M. (1992). Molecular cloning and expression of the cDNA for a novel A2-adenosine receptor subtype. Mol. Endocrinol. 6, 384-393.
10. 10. Pierce, K. D., Furlong, T. J., Selbie, L. A., and Shine, J. (1992). Molecular cloning and expression of an adenosine A2b receptor from human brain. Biochem. Biophys. Res. Commun. 187, 86-93.
11. 11. Zhou, Q., Li, C., Olah, M. E., Johnson, R. A., Stiles, G. L., and Civelli, O. (1992). Molecular cloning and characterization of an adenosine receptor: The A3 adenosine receptor. Proc. Natl. Acad. Sci. USA 89, 7432-7436.
12. 12. Salvatore, C., Jacobson, M. A., Taylor, H. E., Linden, J., and Johnson, R. G. (1993). Molecular cloning and characterization of the human A3 adenosine receptor. Proc. Natl. Acad. Sci. USA 90, 10365-10369.
13. 13. Sajjadi, F. G., and Firestein, G. S. (1993). cDNA cloning and sequence analysis of the human A3 adenosine receptor. Biochim. Biophys. Acta 1179, 105-107.
14. 14. Linden, J., Taylor, H. E., Robera, A. S., Tucker, A. L., Stehle, J. H., Rivkees, S. A., Fink, S. J., and Reppert, S. M. (1993). Molecular cloning and functional expression of a sheep A3 adenosine receptor with widespread tissue distribution. Mol. Pharmacol. 44, 524-532.
15. 6-(3-iodobenzyl) adenosine-5′-N-mehylcarboxamides as A3 selective adenosine agonists. J. Med. Chem. 37, 636-646.
16. 16. Scott-Burden, T., Schini, V. B., Elizodo, E., Junquero, D. C., and Vanhoutte, P.M. (1992). Platelet-derived growth factor suppresses and fibroblast growth factor enhances cytokine-induced production of nitric oxide by cultured smooth muscle cells. Circ. Res. 71, 1088-1100.
17. 17. Wolfe, B. L., Rich, C. B., Goud, H. D., Terpstra, A. J., Bashir, M., Rosenbloom, J., Sonensheim, G. E., and Foster, J. A. (1993). Insulin-like growth factor-I regulates transcription of the elastin gene. J. Biol. Chem. 268, 12418-12426.
18. 18. Ravid, K., Li, Y. C., Rayburn, H. B., and Rosenberg, R. D. (1993). Targeted expression of a conditional oncogene in hematopoietic cells of transgenic mice. J. Cell. Biol. 123, 1545-1553.
19. 19. Anand-Srivastava, M. B., Franks, D. J., Cantin, M., and Genest, J. (1982). Presence of "Ra" and "P"-site receptors for adenosine coupled to adenylyl cyclase in cultured vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 108, 213-219.
20. 20. Inouye, M. (1988). Antisense RNA: Its function and application in gene regulation - A review. Gene 72, 25-35.
21. 21. Meucci, O., Scorziello, A., Avallone, A., Ventra, C., Grimald, M., Berlingieri, M. T., Fusco, A., and Schettini, G. (1994). Alpha 1A- and alpha 1B-adrenergic receptors mediate the effect of norepinephrine on cytosolic calcium levels in rat PC C13 thyroid cells: Thyrotropin modulation of alpha 1B-linked response via a adenosine 3′,5′-monophosphate-protein kinase-A-dependent pathway. Endocrinology 134, 424-431.
22. 22. Angel, P., Smeal, T., Meek, J., and Karin, M. (1989). Jun and v-jun contain multiple regions that participate in transcriptional activation in an interdependent manner. New Biol. 1, 35-43.
23. 23. Chiu, R., Boyle, W. J., Meek, J., Smeal, T., Hunter, T., and Karin, M. (1988). The c-fos protein interacts with c-Jun/AP-1 to stimulate transcription from AP-1 responsive genes. Cell 54, 541-552.
24. 24. Rauscher, R. J., Voulalas, P. J., Franza, B. R., Jr., and Curran, T. (1988). Fos and Jun bind cooperatively to the AP-1 site: Reconstitution in vitro. Gene Dep. 2, 1687-1699.
25. 25. Gubits, R. M., Wollack, J. B., Yu, H., and Liu, W. K. (1990). Activation of adenosine receptors induces c-fos, but not c-jun, expression in neuron-glia hybrids and fibroblasts. Brain Res. Mol. Brain Res. 8, 275-281.
26. 26. Lerman, B. B., and Belardinelli, L. (1991). Cardiac electrophysiology of adenosine. Circulation 83, 1499-1509.
27. 27. Ravid, K., and Lowenstein, J. M. (1988). Changes in adenosine receptors during differentiation of 3T3-F442A cells to adipocytes. Biochem. J. 249, 377-381.
28. 28. Frick, G. P., and Lowenstein, L. M. (1976). Studies of 5′-nucleotidase in the perfused rat heart: Including measurements of the enzyme in perfused skeletal muscle and liver. J. Biol. Chem. 251, 6372-6378.
29. 29. Wang, Z., Zhang, Y., Kamen, D., Lees, E., and Ravid, K. (1995). Cyclin D3 is essential for megakaryocytopoiesis. Blood 86, 3783-3788.
30. 30. Szentmiklosi, A. J., Ujfalusi, A., Cseppento, A., Nosztray, K., Kovacs, P., and Szabo, J. Z. (1995). Adenosine receptors mediate both contractile and relaxant effects of adenosine in main pulmonary artery of guinea pigs. Naunyn-Schmiedeberg Arch. Pharmacol. 351, 417-425.
31. 31. Linden, J. (1994). Cloned adenosine A3 receptors: Pharmacological properties, species differences and receptor function. TiPS 15, 298-306.
32. 32. Zhang, Y., Wang, Z., and Ravid, K. (1996). The cell cycle in polyploid megakaryocytes is associated with reduced activity of cyclin B1-dependent Cdc2 kinase. J. Biol. Chem. 271, 4266-4272.