-
1
-
-
0029071646
-
Functions of the proteasome: The lysis at the end of the tunnel
-
Goldberg AL (1995) Functions of the proteasome: the lysis at the end of the tunnel. Science 268: 522-523.
-
(1995)
Science
, vol.268
, pp. 522-523
-
-
Goldberg, A.L.1
-
2
-
-
0030016595
-
Structure and functions of the 20S and 26S proteasomes
-
Coux O, Tanaka K, Goldberg AL (1996) Structure and functions of the 20S and 26S proteasomes. Annu Rev Biochem 65: 801-847.
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 801-847
-
-
Coux, O.1
Tanaka, K.2
Goldberg, A.L.3
-
3
-
-
0346727127
-
Protein degradation and protection against misfolded or damaged proteins
-
Goldberg AL (2003) Protein degradation and protection against misfolded or damaged proteins. Nature 426: 895-899.
-
(2003)
Nature
, vol.426
, pp. 895-899
-
-
Goldberg, A.L.1
-
4
-
-
33745879143
-
Intracellular protein degradation: From a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting
-
Ciechanover A (2006) Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting. Exp Biol Med (Maywood) 231: 1197-1211.
-
(2006)
Exp Biol Med (Maywood)
, vol.231
, pp. 1197-1211
-
-
Ciechanover, A.1
-
5
-
-
34250819839
-
Intracellular amyloid-beta in Alzheimer's disease
-
LaFerla FM, Green KN, Oddo S (2007) Intracellular amyloid-beta in Alzheimer's disease. Nat Rev Neurosci 8: 499-509.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 499-509
-
-
LaFerla, F.M.1
Green, K.N.2
Oddo, S.3
-
6
-
-
0028979993
-
Amyloid beta-protein inhibits ubiquitin-dependent protein degradation in vitro
-
Gregori L, Fuchs C, Figueiredo-Pereira ME, Van Nostrand WE, Goldgaber D (1995) Amyloid beta-protein inhibits ubiquitin-dependent protein degradation in vitro. J Biol Chem 270: 19702-19708.
-
(1995)
J Biol Chem
, vol.270
, pp. 19702-19708
-
-
Gregori, L.1
Fuchs, C.2
Figueiredo-Pereira, M.E.3
Van Nostrand, W.E.4
Goldgaber, D.5
-
7
-
-
34247185404
-
Disease-associated prion protein oligomers inhibit the 26S proteasome
-
Kristiansen M, Deriziotis P, Dimcheff DE, Jackson GS, Ovaa H, et al. (2007) Disease-associated prion protein oligomers inhibit the 26S proteasome. Mol Cell 26: 175-188.
-
(2007)
Mol Cell
, vol.26
, pp. 175-188
-
-
Kristiansen, M.1
Deriziotis, P.2
Dimcheff, D.E.3
Jackson, G.S.4
Ovaa, H.5
-
8
-
-
0029155831
-
Apoptosis induced by a human milk protein
-
Hakansson A, Zhivotovsky B, Orrenius S, Sabharwal H, Svanborg C (1995) Apoptosis induced by a human milk protein. Proc Natl Acad Sci U S A 92: 8064-8068.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 8064-8068
-
-
Hakansson, A.1
Zhivotovsky, B.2
Orrenius, S.3
Sabharwal, H.4
Svanborg, C.5
-
9
-
-
0034636156
-
Conversion of alpha-lactalbumin to a protein inducing apoptosis
-
Svensson M, Hakansson A, Mossberg AK, Linse S, Svanborg C (2000) Conversion of alpha-lactalbumin to a protein inducing apoptosis. Proc Natl Acad Sci U S A 97: 4221-4226.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 4221-4226
-
-
Svensson, M.1
Hakansson, A.2
Mossberg, A.K.3
Linse, S.4
Svanborg, C.5
-
10
-
-
34548073069
-
Bladder cancers respond to intravesical instillation of HAMLET (human alpha-lactalbumin made lethal to tumor cells)
-
Mossberg AK, Wullt B, Gustafsson L, Mansson W, Ljunggren E, et al. (2007) Bladder cancers respond to intravesical instillation of HAMLET (human alpha-lactalbumin made lethal to tumor cells). Int J Cancer 121: 1352-1359.
-
(2007)
Int J Cancer
, vol.121
, pp. 1352-1359
-
-
Mossberg, A.K.1
Wullt, B.2
Gustafsson, L.3
Mansson, W.4
Ljunggren, E.5
-
11
-
-
1542405871
-
Human alpha-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival
-
Fischer W, Gustafsson L, Mossberg AK, Gronli J, Mork S, et al. (2004) Human alpha-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival. Cancer Res 64: 2105-2112.
-
(2004)
Cancer Res
, vol.64
, pp. 2105-2112
-
-
Fischer, W.1
Gustafsson, L.2
Mossberg, A.K.3
Gronli, J.4
Mork, S.5
-
12
-
-
2942746332
-
Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid
-
Gustafsson L, Leijonhufvud I, Aronsson A, Mossberg AK, Svanborg C (2004) Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid. N Engl J Med 350: 2663-2672.
-
(2004)
N Engl J Med
, vol.350
, pp. 2663-2672
-
-
Gustafsson, L.1
Leijonhufvud, I.2
Aronsson, A.3
Mossberg, A.K.4
Svanborg, C.5
-
13
-
-
0014023116
-
The substitution of alpha-lactalbumin for the B protein of lactose synthetase
-
Ebner KE, Denton WL, Brodbeck U (1966) The substitution of alpha-lactalbumin for the B protein of lactose synthetase. Biochem Biophys Res Commun 24: 232-236.
-
(1966)
Biochem Biophys Res Commun
, vol.24
, pp. 232-236
-
-
Ebner, K.E.1
Denton, W.L.2
Brodbeck, U.3
-
14
-
-
0014010214
-
Resolution of a soluble lactose synthetase into two protein components and solubilization of microsomal lactose synthetase
-
Brodbeck U, Ebner KE (1966) Resolution of a soluble lactose synthetase into two protein components and solubilization of microsomal lactose synthetase. J Biol Chem 241: 762-764.
-
(1966)
J Biol Chem
, vol.241
, pp. 762-764
-
-
Brodbeck, U.1
Ebner, K.E.2
-
15
-
-
0014251737
-
The role of alpha-lactalbumin and the A protein in lactose synthetase: A unique mechanism for the control of a biological reaction
-
Brew K, Vanaman TC, Hill RL (1968) The role of alpha-lactalbumin and the A protein in lactose synthetase: a unique mechanism for the control of a biological reaction. Proc Natl Acad Sci U S A 59: 491-497.
-
(1968)
Proc Natl Acad Sci U S A
, vol.59
, pp. 491-497
-
-
Brew, K.1
Vanaman, T.C.2
Hill, R.L.3
-
16
-
-
10744223979
-
Alpha-lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells)
-
Svensson M, Fast J, Mossberg AK, Duringer C, Gustafsson L, et al. (2003) Alpha-lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells). Protein Sci 12: 2794-2804.
-
(2003)
Protein Sci
, vol.12
, pp. 2794-2804
-
-
Svensson, M.1
Fast, J.2
Mossberg, A.K.3
Duringer, C.4
Gustafsson, L.5
-
17
-
-
0030059690
-
The molten globule state of alpha-lactalbumin
-
Kuwajima K (1996) The molten globule state of alpha-lactalbumin. FASEB J 10: 102-109.
-
(1996)
FASEB J
, vol.10
, pp. 102-109
-
-
Kuwajima, K.1
-
18
-
-
0030025082
-
Disulfide determinants of calcium-induced packing in alpha-lactalbumin
-
Wu LC, Schulman BA, Peng ZY, Kim PS (1996) Disulfide determinants of calcium-induced packing in alpha-lactalbumin. Biochemistry 35: 859-863.
-
(1996)
Biochemistry
, vol.35
, pp. 859-863
-
-
Wu, L.C.1
Schulman, B.A.2
Peng, Z.Y.3
Kim, P.S.4
-
19
-
-
0033200063
-
Protein misfolding, evolution and disease
-
Dobson CM (1999) Protein misfolding, evolution and disease. Trends Biochem Sci 24: 329-332.
-
(1999)
Trends Biochem Sci
, vol.24
, pp. 329-332
-
-
Dobson, C.M.1
-
20
-
-
0028985861
-
Conformational constraints in protein degradation by the 20S proteasome
-
Wenzel T, Baumeister W (1995) Conformational constraints in protein degradation by the 20S proteasome. Nat Struct Biol 2: 199-204.
-
(1995)
Nat Struct Biol
, vol.2
, pp. 199-204
-
-
Wenzel, T.1
Baumeister, W.2
-
21
-
-
65349103445
-
-
Gustafsson L (2005) HAMLET - In vivo effects and mechanisms of tumor-cell death [Doctoral Thesis]. Lund: Lund University.
-
Gustafsson L (2005) HAMLET - In vivo effects and mechanisms of tumor-cell death [Doctoral Thesis]. Lund: Lund University.
-
-
-
-
22
-
-
0024343068
-
Calcium regulates folding and disulfide-bond formation in alpha-lactalbumin
-
Rao KR, Brew K (1989) Calcium regulates folding and disulfide-bond formation in alpha-lactalbumin. Biochem Biophys Res Commun 163: 1390-1396.
-
(1989)
Biochem Biophys Res Commun
, vol.163
, pp. 1390-1396
-
-
Rao, K.R.1
Brew, K.2
-
23
-
-
0027269511
-
Pathway of disulfide-coupled unfolding and refolding of bovine alpha-lactalbumin
-
Ewbank JJ, Creighton TE (1993) Pathway of disulfide-coupled unfolding and refolding of bovine alpha-lactalbumin. Biochemistry 32: 3677-3693.
-
(1993)
Biochemistry
, vol.32
, pp. 3677-3693
-
-
Ewbank, J.J.1
Creighton, T.E.2
-
24
-
-
0032492714
-
Structural evidence for the presence of a secondary calcium binding site in human alpha-lactalbumin
-
Chandra N, Brew K, Acharya KR (1998) Structural evidence for the presence of a secondary calcium binding site in human alpha-lactalbumin. Biochemistry 37: 4767-4772.
-
(1998)
Biochemistry
, vol.37
, pp. 4767-4772
-
-
Chandra, N.1
Brew, K.2
Acharya, K.R.3
-
25
-
-
0033168453
-
Molecular dynamics simulations of human alpha-lactalbumin: Changes to the structural and dynamical properties of the protein at low pH
-
Smith LJ, Dobson CM, van Gunsteren WF (1999) Molecular dynamics simulations of human alpha-lactalbumin: changes to the structural and dynamical properties of the protein at low pH. Proteins 36: 77-86.
-
(1999)
Proteins
, vol.36
, pp. 77-86
-
-
Smith, L.J.1
Dobson, C.M.2
van Gunsteren, W.F.3
-
26
-
-
0344944630
-
Protein aggregation and aggregate toxicity: New insights into protein folding, misfolding diseases and biological evolution
-
Stefani M, Dobson CM (2003) Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution. J Mol Med 81: 678-699.
-
(2003)
J Mol Med
, vol.81
, pp. 678-699
-
-
Stefani, M.1
Dobson, C.M.2
-
27
-
-
0842281551
-
Principles of protein folding, misfolding and aggregation
-
Dobson CM (2004) Principles of protein folding, misfolding and aggregation. Semin Cell Dev Biol 15: 3-16.
-
(2004)
Semin Cell Dev Biol
, vol.15
, pp. 3-16
-
-
Dobson, C.M.1
-
28
-
-
0036853914
-
Orchestrating the unfolded protein response in health and disease
-
Kaufman RJ (2002) Orchestrating the unfolded protein response in health and disease. J Clin Invest 110: 1389-1398.
-
(2002)
J Clin Invest
, vol.110
, pp. 1389-1398
-
-
Kaufman, R.J.1
-
29
-
-
0028120343
-
Scrapie amyloid (prion) protein has the conformational characteristics of an aggregated molten globule folding intermediate
-
Safar J, Roller PP, Gajdusek DC, Gibbs CJ Jr (1994) Scrapie amyloid (prion) protein has the conformational characteristics of an aggregated molten globule folding intermediate. Biochemistry 33: 8375-8383.
-
(1994)
Biochemistry
, vol.33
, pp. 8375-8383
-
-
Safar, J.1
Roller, P.P.2
Gajdusek, D.C.3
Gibbs Jr, C.J.4
-
30
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
Prusiner SB (1982) Novel proteinaceous infectious particles cause scrapie. Science 216: 136-144.
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
31
-
-
0034597824
-
Structural basis for the activation of 20S proteasomes by 11S regulators
-
Whitby FG, Masters EI, Kramer L, Knowlton JR, Yao Y, et al. (2000) Structural basis for the activation of 20S proteasomes by 11S regulators. Nature 408: 115-120.
-
(2000)
Nature
, vol.408
, pp. 115-120
-
-
Whitby, F.G.1
Masters, E.I.2
Kramer, L.3
Knowlton, J.R.4
Yao, Y.5
-
33
-
-
0033766480
-
A gated channel into the proteasome core particle
-
Groll M, Bajorek M, Kohler A, Moroder L, Rubin DM, et al. (2000) A gated channel into the proteasome core particle. Nat Struct Biol 7: 1062-1067.
-
(2000)
Nat Struct Biol
, vol.7
, pp. 1062-1067
-
-
Groll, M.1
Bajorek, M.2
Kohler, A.3
Moroder, L.4
Rubin, D.M.5
-
34
-
-
0030094434
-
Activation of 20S proteasomes from spinach leaves by fatty acids
-
Watanabe N, Yamada S (1996) Activation of 20S proteasomes from spinach leaves by fatty acids. Plant Cell Physiol 37: 147-151.
-
(1996)
Plant Cell Physiol
, vol.37
, pp. 147-151
-
-
Watanabe, N.1
Yamada, S.2
-
35
-
-
0030006201
-
Role of the ceramide-signaling pathway in cytokine responses to P-fimbriated Escherichia coli
-
Hedlund M, Svensson M, Nilsson A, Duan RD, Svanborg C (1996) Role of the ceramide-signaling pathway in cytokine responses to P-fimbriated Escherichia coli. J Exp Med 183: 1037-1044.
-
(1996)
J Exp Med
, vol.183
, pp. 1037-1044
-
-
Hedlund, M.1
Svensson, M.2
Nilsson, A.3
Duan, R.D.4
Svanborg, C.5
-
36
-
-
2642704194
-
Apoptosis of renal cortical cells in the hemolytic-uremic syndrome: In vivo and in vitro studies
-
Karpman D, Hakansson A, Perez MT, Isaksson C, Carlemalm E, et al. (1998) Apoptosis of renal cortical cells in the hemolytic-uremic syndrome: in vivo and in vitro studies. Infect Immun 66: 636-644.
-
(1998)
Infect Immun
, vol.66
, pp. 636-644
-
-
Karpman, D.1
Hakansson, A.2
Perez, M.T.3
Isaksson, C.4
Carlemalm, E.5
-
37
-
-
0033525523
-
Molecular characterization of alpha-lactalbumin folding variants that induce apoptosis in tumor cells
-
Svensson M, Sabharwal H, Hakansson A, Mossberg AK, Lipniunas P, et al. (1999) Molecular characterization of alpha-lactalbumin folding variants that induce apoptosis in tumor cells. J Biol Chem 274: 6388-6396.
-
(1999)
J Biol Chem
, vol.274
, pp. 6388-6396
-
-
Svensson, M.1
Sabharwal, H.2
Hakansson, A.3
Mossberg, A.K.4
Lipniunas, P.5
-
38
-
-
33644778718
-
Rapid identification of 14-3-3-binding proteins by protein microarray analysis
-
Satoh J, Nanri Y, Yamamura T (2006) Rapid identification of 14-3-3-binding proteins by protein microarray analysis. J Neurosci Methods 152: 278-288.
-
(2006)
J Neurosci Methods
, vol.152
, pp. 278-288
-
-
Satoh, J.1
Nanri, Y.2
Yamamura, T.3
-
39
-
-
0025916703
-
Crystal structure of human alpha-lactalbumin at 1.7 A resolution
-
Acharya KR, Ren JS, Stuart DI, Phillips DC, Fenna RE (1991) Crystal structure of human alpha-lactalbumin at 1.7 A resolution. J Mol Biol 221: 571-581.
-
(1991)
J Mol Biol
, vol.221
, pp. 571-581
-
-
Acharya, K.R.1
Ren, J.S.2
Stuart, D.I.3
Phillips, D.C.4
Fenna, R.E.5
-
40
-
-
0029881007
-
MOLMOL: A program for display and analysis of macromolecular structures
-
Koradi R, Billeter M, Wuthrich K (1996) MOLMOL: a program for display and analysis of macromolecular structures. J Mol Graph 14: 51-55, 29-32.
-
(1996)
J Mol Graph
, vol.14
, Issue.51-55
, pp. 29-32
-
-
Koradi, R.1
Billeter, M.2
Wuthrich, K.3
|