α-lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human α-lactalbumin made lethal to tumor cells)

Protein Science

Volumn 12, Issue 12, 2003, Pages 2794-2804

  Svensson, Malin ^a   Fast, Jonas ^a   Mossberg, Ann Kristin ^a   Düringer, Caroline ^a   Gustafsson, Lotta ^a   Hallgren, Oskar ^a   Brooks, Charles L ^b   Berliner, Lawrence ^c   Linse, Sara ^a   Svanborg, Catharina ^a  

^a LUND UNIVERSITY   (Sweden)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF DENVER   (United States)

Author keywords

Lactalbumin; Ca2+ binding site; HAMLET; Protein folding; Tumor cell death

Indexed keywords

ALPHA LACTALBUMIN; CALCIUM ION; SOLVENT;

APOPTOSIS; ARTICLE; BINDING AFFINITY; BINDING SITE; CALCIUM BINDING; CELL DEATH; CONTROLLED STUDY; HUMAN; HUMAN CELL; KILLER CELL; PRIORITY JOURNAL; PROTEIN FOLDING; TUMOR CELL;

AMINO ACIDS; ANIMALS; APOPTOSIS; BINDING SITES; CALCIUM; CATTLE; CELL LINE, TUMOR; CIRCULAR DICHROISM; CULTURE MEDIA; HUMANS; LACTALBUMIN; LEUKEMIA L1210; MICE; MODELS, MOLECULAR; MUTATION; OLEIC ACID; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY;

BOVINAE;

EID: 10744223979     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.0231003     Document Type: Article

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