Apoptosis of renal cortical cells in the hemolytic-uremic syndrome: In vivo and in vitro studies

Infection and Immunity

Volumn 66, Issue 2, 1998, Pages 636-644

  Karpman, Diana ^a   Håkansson, Anders ^a   Ferez, Maria Thereza R ^a   Isaksson, Christina ^a   Carlemalm, Eric ^a   Caprioli, Alfredo ^b   Svanborg, Catharina ^a  

^a LUND UNIVERSITY   (Sweden)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL DEATH; CELL STIMULATION; CELL ULTRASTRUCTURE; CHROMATIN CONDENSATION; EPITHELIUM CELL; GENE TARGETING; HEMOLYTIC UREMIC SYNDROME; HUMAN; HUMAN TISSUE; KIDNEY CORTEX; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; TISSUE INJURY;

EID: 2642704194     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.2.636-644.1998     Document Type: Article

References (56)

1. Bardales, R. H., S.-S. Xie, and S.-M. Hsu. 1997. In situ DNA fragmentation assay for detection of apoptosis in paraffin-embedded tissue sections. Am. J. Clin. Pathol. 107:332-336.
2. Barrett, T. J., M. E. Potter, and I. K. Wachsmuth. 1989. Continuous peritoneal infusion of Shiga-like toxin-II (SLT-II) as a model for SLT-II-induced diseases. J. Infect. Dis. 159:774-777.
3. Boyce, T. G., D. L. Swerdlow, and P. M. Griffin. 1995. Escherichia coli O157:H7 and the hemolytic uremic syndrome. N. Engl. J. Med. 333:364-368.
4. Caprioli, A., I. Luzzi, F. Rosmini, P. Pasquini, R. Cirrincione, A. Gianviti, M. C. Matteucci, G. Rizzoni, and the HUS Italian Study Group. 1992. Hemolytic-uremic syndrome and vero cytotoxin-producing Escherichia coli infection in Italy. J. Infect. Dis. 166:154-158.
5. Chae, C., R. A. Moxley, J. Christopher-Hennings, D. H. Francis, and M. J. Wannemuehler. 1994. Shiga-like toxin-II-producing Escherichia coli O157:H7 infection in gnotobiotic piglets: protection against brain vascular lesions with SLT-II antiserum, p. 241-244. In M. A. Karmali and A. G. Goglio (ed.). Recent advances in verocytotoxin producing Escherichia coli infections. Elsevier Science, Amsterdam, The Netherlands.
6. Chang, M. P., J. Bramhall, S. Graves, B. Bonavida, and B. J. Wisnieski. 1989. Internucleosomal DNA cleavage precedes Diphtheria toxin-induced cytolysis. J. Biol. Chem. 264:15261-15267.
7. Chart, H., H. R. Smith, S. M. Scotland, B. Rowe, D. V. Milford, and C. M. Taylor. 1991. Serological identification of Escherichia coli O157:H7 infection in haemolytic uremic syndrome. Lancet 337:138-140.
8. Chen, Y., M. R. Smith, K. Thirumalai, and A. Zychlinsky. 1996. A bacterial invasin induces macrophage apoptosis by binding directly to ICE. EMBO J. 15:3853-3860.
9. 2+ associated with apoptosis. p. 41-55. In L. M. Schwarz, and B. A. Osborne (ed.). Cell death. Academic Press, San Diego. Calif.
10. Fitzpatrick, M. M., M. D. S. Walters, R. S. Trompeter, M. J. Dillon, and T. M. Barratt. 1993. Atypical (non-diarrhea-associated) hemolytic-uremic syndrome in childhood. J. Pediatr. 122:532-537.
11. Francis, D. H., J. E. Collins, and J. R. Duimstra. 1986. Infection of gnotobiotic pigs with an Escherichia coli O157:H7 strain associated with an out-break of hemorrhagic colitis. Infect. Immun. 51:953-956.
12. Gavrieli, Y., Y. Sherman, and S. A. Ben-Sasson. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:493-501.
13. Gentry, M. K., and J. M. Dalrymple. 1980. Quantitive microtiter cytotoxicity assay for Shigella toxin. J. Clin. Microbiol. 12:361-366.
14. Griffin, P. M. 1995. Escherichia coli O157:H7 and other enterohemorrhagic Escherichia coli, p. 739-761. In M. J. Blaser, P. D. Smith, J. I. Ravdin, H. B. Greenberg, and R. L. Cuerrant (ed.). Infections of the gastrointestinal tract. Raven Press Ltd., New York, N.Y.
15. Griffin, P. M., S. M. Ostroff, R. V. Tauxe, K. D. Greene, J. G. Wells, J. H. Lewis, and P. A. Blake. 1988. Illnesses associated with Escherichia coli O157:H7 infections. Ann. Intern. Med. 109:705-712.
16. Habib, R. 1992. Pathology of the hemolytic uremic syndrome, p. 315-353. In B. S. Kaplan, R. S. Trompeter, and J. L. Moake (ed.), Hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. Marcel Dekker Inc., New York, N.Y.
17. Hagberg, L., I. Engberg, R. Freter, J. Lam, S. Olling, and C. Svanborg-Edén. 1983. Ascending unobstructed urinary tract infection in mice caused by pyelonephritogenic Escherichia coli of human origin. Infect. Immun. 40:273-283.
18. Harel, Y., M. Silva, B. Giroir, A. Weinberg, T. B. Cleary, and B. Beutler. 1993. A reporter transgene indicates renal-specific induction of tumor necrosis factor (TNF) by Shiga-like toxin. J. Clin. Invest. 92:2110-2116.
19. Inward, C. D., J. Williams, I. Chant, J. Crocker, D. V. Milford, P. E. Rose, and C. M. Taylor. 1995. Verocytotoxin-1 induces apoptosis in vero cells. J. Infect. 30:213-218.
20. Kaplan, B. S. 1991. Hemolytic-uremic syndrome and thrombotic thrombocytopenic purpura, p. 326-329. In H. R. Jacobson, G. E. Striker, and S. Klahr (ed.), The principles and practice of nephrology. B. C. Decker, Philadelphia, Pa.
21. Karmali, M. A., M. Petric, C. Lim, R. Cheung, and G. S. Arbus. 1985. Sensitive method for detecting low numbers of verotoxin-producing Escherichia coli in mixed cultures by use of colony sweeps and polymyxin extraction of verotoxin. J. Clin. Microbiol. 22:614-619.
22. Karmali, M. A., M. Petric, C. Lim, P. C. Fleming, G. S. Arbus, and H. Lior. 1985. The association between idiopathic hemolytic uremic syndrome and infection by verotoxin-producing Escherichia coli. J. Infect. Dis. 151:775-782.
23. Karpman, D., A. Andreasson, H. Thysell, B. S. Kaplan, C. Svanborg. 1995. Cytokines in childhood hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. Pediatr. Nephrol. 9:694-699.
24. Karpman, D., H. Connell, M. Svensson, F. Scheutz, P. Alm, and C. Svanborg. 1997. The role of lipopolysaccharide and Shiga-like toxin in a mouse model of Escherichia coli O157:H7 infection. J. Infect. Dis. 175:611-620.
25. Keenan, K. P., D. D. Sharpnack, H. Collins, S. B. Formal, and A. D. O'Brien. 1986. Morphologic evaluation of the effects of Shiga toxin and E. coli Shigalike toxin on the rabbit intestine. Am. J. Pathol. 125:69-80.
26. Kerr, J. F. R., A. H. Wyllie, and A. R. Currie. 1972. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26:239-257.
27. Keusch, G. T., D. W. K. Acheson, L. Aaldering, J. Erban, and M. S. Jacewicz. 1996. Comparison of the effects of Shiga-like toxin I on cytokine- and butyrate-treated human umbilical and saphenous vein endothelial cells. J. Infect. Dis. 173:1164-1170.
28. Levin, M., and T. M. Barratt. 1984. Haemolytic uraemic syndrome. Arch. Dis. Child. 59:397-100.
29. Louise, C. B., and T. G. Obrig. 1991. Shiga toxin-associated hemolyticuremic syndrome: combined cytotoxic effects of Shiga toxin, interleukin-1β, and tumor necrosis factor alpha on human vascular endothelial cells in vitro. Infect. Immun. 59:4173-4179.
30. Louise, C. B., and T. G. Obrig. 1995. Specific interaction of Escherichia coli O157:H7-derived Shiga-like toxin II with human renal endothelial cells. J. Infect. Dis. 172:1397-1401.
31. Mangeney, M., C. A. Lingwood, S. Taga, B. Caillou, T. Tursz, and J. Wiels. 1993. Apoptosis induced in Burkitt's lymphoma cells via Gb3/CD77, a glycolipid antigen. Cancer Res. 53:5314-5319.
32. McConkey, D. J., P. Nicotera, and S. Orrenius, 1994. Signaling and chromatin fragmentation in thymocyte apoptosis. Immunol. Rev. 142:343-363.
33. McKee, M. L., and A. D. O'Brien. 1995. Investigation of enterohemorrhagic Escherichia coli O157:H7 adherence characteristics and invasion potential reveals a new attachment pattern shared by intestinal E. coli. Infect. Immun. 63:2070-2074.
34. Mitra, D., E. A. Jaffe, B. Weksler, K. A. Hajjar, C. Soderland, and J. Laurence. 1997. Thrombotic thrombocytopenic purpura and sporadic hemolytic-uremic syndrome plasmas induce apoptosis in restricted lineages of human microvascular endothelial cells. Blood 89:1224-1234.
35. Moll, R., W. W. Franke, and D. L. Schiller, 1982. The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 31:11-24.
36. Obrig, T. G., P. J. Del Vecchio, J. E. Brown, T. P. Moran, B. M. Rowland, T. K. Judge, and S. W. Rothman. 1988. Direct cytotoxic action of Shiga toxin on human vascular endothelial cells. Infect. Immun. 56:2373-2378.
37. Obrig, T. G., C. B. Louise, C. A. Lingwood, B. Boyd, L. Barley-Maloney, and T. O. Daniel. 1993. Endothelial heterogeneity in Shiga toxin receptors and responses. J. Biol. Chem. 268:15484-15488.
38. Obrig, T. G., T. P. Moran, and J. E. Brown. 1987. The mode of action of Shiga toxin on peptide elongation of eukaryotic protein synthesis. Biochem. J. 244:287-294.
39. Pai, C. H., J. K. Kelly, and G. L. Meyers. 1986. Experimental infection of infant rabbits with vero toxin-producing Escherichia coli. Infect. Immun. 51:16-23.
40. Perera, L. P., L. R. M. Marques, and A. D. O'Brien. 1988. Isolation and characterization of monoclonal antibodies to Shiga-like toxin II of enterohemorrhagic Escherichia coli and use of the monoclonal antibodies in a colony enzyme-linked immunosorbent assay. J. Clin. Microbiol. 26:2127-2131.
41. Ferez, M. R., K. Arnér, and A. Håkansson. 1997. DNA fragmentation characteristic of apoptosis and cell loss induced by kainic acid in rabbit retinas. Neurochem. Int. 31:251-260.
42. Petric, M., M. A. Karmali, G. S. Arbus, M. Roscoe, S. Louie, and R. Cheung. 1987. Effects of cycloehximide and puromycin on cytotoxic activity of Escherichia coli verocytotoxin (Shiga-like toxin). J. Clin. Microbiol. 25:1265-1268.
43. Reisbig, R., S. Olsnes, and K. Eiklid. 1981. The cytotoxic activity of Shigella toxin. J. Biol. Chem. 256:8739-8744.
44. Sandvig, K., K. Prydz, M. Ryd, and B. van Deurs. 1991. Endocytosis and intracellular transport of the glycolipid-binding ligand Shiga toxin in polarized MDCK cells. J. Cell Biol. 113:553-562.
45. Sandvig, K., and B. van Deurs. 1992. Toxin-induced cell lysis: protection by 3-methyladenine and cycloheximide. Exp. Cell Res. 200:253-262.
46. Sjöblad, S., B. Larsson, G. Kahlmeter, and T. Wadström. 1989. Pojke fick SLT-associerat hemolytiskt uremiskt syndrom. Läkartidningen 86:2595-2596.
47. Tesh, V. L., J. A. Burris, J. W. Owens, V. M. Gordon, E. A. Wadolkowski, A. D. O'Brien, and J. E. Samuel. 1993. Comparison of the relative toxicities of Shiga-like toxins type I and type II for mice. Infect. Immun. 61:3392-3402.
48. Tzipori, S., H. Karen, K. I. Wachsmuth, R. M. Robins-Browne, A. D. O'Brien, H. Lior, M. L. Cohen, J. Smithers, and M. M. Levine. 1987. Role of a 60-megadalton plasmid and Shiga-like toxins in the pathogenesis of infection caused by enterohemorrhagic Escherichia coli O157:H7 in gnotobiotic piglets. Infect. Immun. 55:3117-3125.
49. van de Kar, N. C. A. J., L. A. H. Monnens, M. A. Karmali, and V. W. M. van Hinsbergh. 1992. Tumor necrosis factor and interleukin-1 induce expression of the verocytotoxin receptor globotriaosylceramide on human endothelial cells: implications for the pathogenesis of the hemolytic uremic syndrome. Blood 80:2755-2764.
50. van Setten, P. A., V. W. van Hinsbergh, T. J. van der Velden, N. C. van de Kar, M. Vermeer, J. D. Mahan, K. J. Assmann, L. P. van den Heuvel, and L. A. Monnens. 1997. Effects of TNF alpha on verocytotoxin cytotoxicity in purified human glomerular microvascular endothelial cells. Kidney Int. 51:1245-1256.
51. Wadolkowski, E. A., J. A. Burris, and A. D. O'Brien. 1990. Mouse model for colonization and disease caused by enterohemorrhagic Escherichia coli O157:H7. Infect. Immun. 58:2438-2445.
52. Wadolkowski, E. A., L. M. Sung, J. A. Burris, J. E. Samuel, and A. D. O'Brien. 1990. Acute renal tubular necrosis and death of mice orally infected with Escherichia coli strains that produce Shiga-like toxin type II. Infect. Immun. 58:3959-3965.
53. Weibel, E. W., and G. E. Palade. 1964. New cytoplasmic components in arterial endothelia. J. Cell Biol. 23:101-112.
54. Wojta, J., R. L. Hoover, and T. O. Daniel. 1989. Vascular origin determines plasminogen activator expression in human endothelial cells. J. Biol. Chem. 264:2846-2852.
55. Zhivotovsky, B., D. Wade, A. Gahm, S. Orrenius, and P. Nicotera. 1994 Formation of 50 kbp chromatin fragments in isolated liver nuclei is mediated by protease and endonuclease activation. FEBS Lett. 351:150-154.
56. Zychlinsky, A., M. C. Prevost, and P. J. Sansonetti. 1992. Shigella flexneri induces apoptosis in infected macrophages. Nature 358:167-169.