Molecular characterization of α-lactalbumin folding variants that induce apoptosis in tumor cells

Journal of Biological Chemistry

Volumn 274, Issue 10, 1999, Pages 6388-6396

  Svensson, Malin ^a   Sabharwal, Hemant ^b   Håkansson, Anders ^a   Mossberg, Ann Kristin ^a   Lipniunas, Peter ^c,d   Leffler, Hakon ^a   Svanborg, Catharina ^a   Linse, Sara ^a  

^a LUND UNIVERSITY   (Sweden)

^b ROCKEFELLER UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA LACTALBUMIN; CASEIN; MONOMER; OLIGOMER;

AMINO ACID SEQUENCE; ANIMAL CELL; ANION EXCHANGE CHROMATOGRAPHY; APOPTOSIS; ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; FLUORESCENCE SPECTROSCOPY; GEL PERMEATION CHROMATOGRAPHY; LEUKEMIA L 1210; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN VARIANT; SEQUENCE HOMOLOGY; TUMOR CELL; ULTRAVIOLET SPECTROSCOPY;

AMINO ACID SEQUENCE; APOPTOSIS; DIMERIZATION; FEMALE; HUMANS; LACTALBUMIN; MILK, HUMAN; MOLECULAR SEQUENCE DATA; NEOPLASMS; PROTEIN FOLDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033525523     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.10.6388     Document Type: Article

References (38)

1. Lonnerdal, B., and Forsum, E. (1985) Am. J. Clin. Nutr. 41, 113-120
2. Redhead, K., Hill,T., and Mulloy, B. (1990) FEMS Microbiol. Lett. 70, 269-274
3. Sarkar, N. H., Charney, J., Dion, A., and Moore, D. (1973) Cancer Res. 33, 626-629
4. Svanborg, C., Aniansson, G., Mestecky, J., Sabharwal, H., and Wold, A. (1991) Adv. Exp. Med. Biol. 310, 167-171
5. Andersson, B., Dahmén, J., Freijd, T., Leffler, H., Magnusson, G., Noori, G., and Svanborg-Edén, C. (1983) J. Exp. Med. 158, 559-570
6. Davis, M. K., Savitz, D. A., and Graubard, B. I. (1988) Lancet ii, 365-368
7. Hakansson, A., Zhivotovsky, B., Orrenius, S., Sabharwal, H., and Svanborg, C. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8064-8068
8. Heine, W. E., Klein, P. D., and Reeds, P. J. (1991) J. Nutr. 121, 277-283
9. Brew, K., and Grobler, J. (1992) in Advanced Dairy Chemistry 1 (Fox, P., ed) pp. 191-229, Elsevier, London
10. Hill, R., and Brew, K. (1975) Adv. Enzymol. Relat. Mol. Biol. 43, 411-490
11. Acharya, K. R., Ren, J. S., Stuart, D. I., Phillips, D. C., and Fenna, R. E. (1991) J. Mol. Biol. 221, 571-581
12. Aramini, J. M., Hiraoki, T., Grace, M. R., Swaddle, T. W., Chiancone, E., and Vogel, H. J. (1996) Biochim. Biophys. Acta 1293, 72-82
13. Ren, J., Stuart, D. I., and Acharya, K. R. (1993) J. Biol. Chem. 268, 19292-19298
14. Musci, G., and Berliner, L. (1985) Biochemistry 24, 6945-6948
15. Rao, K. R., and Brew, K. (1989) Biochem. Biophys. Res. Commun. 163, 1390-1396
16. Wu, L. C., Schulman, B. A., Peng, Z. Y., and Kim, P. S. (1996) Biochemistry 35, 859-863
17. Dolgikh, D., Gilmanshin, R., Brazhnikov, E., Bychkova, V., Semisotnov, G., Venyaminov, S., and Ptitsyn, O. (1981) FEBS Lett. 136, 311-315
18. Kuwajima, K. (1985) Proteins Struct. Funct. Genet. 6, 87-103
19. Kuwajima, K. (1996) FASEB J. 10, 102-109
20. Pfeil, W. (1987) Biochim. Biophys. Acta 911, 114-116
21. Sander, B., Andersson, J., and Andersson, U. (1991) Immunol. Rev. 119, 65-92
22. Sreerama, N., and Woody, R. (1993) Anal. Biochem. 209, 32-44
23. Schmidt, D. W., and Ebner, K. E. (1972) Biochim. Biophys. Acta 263, 714-720
24. Hákansson, A., Andréasson, J., Karpman, D., Zhivotovsky, B., Orrenius, S., and Svanborg, C. (1999) Exp. Cell Res. 246, in press
25. Bychkova, V., Pain, R., and Ptitsyn, O. (1988) FEBS Lett. 238, 231-234
26. Banuelos, S., and Muga, A. (1995) J. Biol. Chem. 270, 29910-29915
27. Schulman, B. A., Redfield, C., Peng, Z., Dobson, C. N., and Kim, P. S. (1995) J. Mol. Biol. 253, 651-657
28. Semisotnov, G., Rodinova, N., Kutyshenko, V., Ebert, B., Blank, J., and Ptitsyn, O. (1987) FEBS Lett. 244, 9-13
29. Semisotnov, G. V., Rodionova, N. A., Razgulyaev, O. I., Uversky, V. N., Gripas, A. F., and Gilmanshin, R. I. (1991) Biopolymers 31, 119-128
30. Dolgikh, D., Kolomiets, A., Bolotina, I., and Ptitsyn, O. (1984) FEBS Lett. 165, 88-92
31. Prusiner, S., McKinley, M., Bowman, K., Bolton, D., Bendheim, P., Groth, D., and Glenner, G. (1983) Cell 35, 349-358
32. Safar, J., Roller, P., Gajdusek, D., and Gibbs, C. J. (1993) Protein Sci. 2, 2206-2216
33. Safar, J., Roller, P., Gajdusek, D., and Gibbs, C. J., Jr. (1993) J. Biol. Chem. 268, 20276-20284
34. Basler, K., Oesch, B., Scott, M., Westaway, D., Wälichli, M., Groth, D., McKinely, M., Prusiner, S., and Weissmann, C. (1986) Cell 46, 417-428
35. Stahl, N., Baldwin, M., Teplow, D., Hood, L., Gibson, B., Burlingame, A., and Prusiner, S. (1993) Biochemistry 32, 1991-2002
36. Safar, J., Roller, P. P., Gajdusek, D., and Gibbs, C. J., Jr. (1994) Biochemistry 33, 8375-8383
37. Ferrin, T., Huang, C., Jarvis, L., and Langridge, R. (1988) J. Mol. Graph. 6, 13-27
38. Wu, L. C., Peng, Z.-Y., and Kim, P. S. (1995) Structural Biol. 2, 281-286