-
1
-
-
38549166301
-
GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells
-
Mantel PY, Kuipers H, Boyman O, Rhyner C, Ouaked N, Ruckert B, Karagiannidis C, Lambrecht BN, Hendriks RW, Crameri R, Akdis CA, Blaser K, Schmidt-Weber CB: GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells. PLoS Biol 5: e329, 2007
-
(2007)
PLoS Biol
, vol.5
-
-
Mantel, P.Y.1
Kuipers, H.2
Boyman, O.3
Rhyner, C.4
Ouaked, N.5
Ruckert, B.6
Karagiannidis, C.7
Lambrecht, B.N.8
Hendriks, R.W.9
Crameri, R.10
Akdis, C.A.11
Blaser, K.12
Schmidt-Weber, C.B.13
-
2
-
-
0028179006
-
Lymphocyte responses and cytokines
-
Paul WE, Seder RA: Lymphocyte responses and cytokines. Cell 76: 241-251, 1994
-
(1994)
Cell
, vol.76
, pp. 241-251
-
-
Paul, W.E.1
Seder, R.A.2
-
3
-
-
0030474264
-
Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection
-
Hancock WW, Sayegh MH, Zheng XG, Peach R, Linsley PS, Turka LA: Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection. Proc Natl Acad Sci U S A 93: 13967-13972, 1996
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 13967-13972
-
-
Hancock, W.W.1
Sayegh, M.H.2
Zheng, X.G.3
Peach, R.4
Linsley, P.S.5
Turka, L.A.6
-
4
-
-
0029164864
-
Mechanisms of acquired thy- mic tolerance in experimental autoimmune encephalomyelitis: Thymic dendritic-enriched cells induce specific peripheral T cell unresponsiveness in vivo
-
Khoury SJ, Gallon L, Chen W, Betres K, Russell ME, Hancock WW, Carpenter CB, Sayegh MH, Weiner HL: Mechanisms of acquired thy- mic tolerance in experimental autoimmune encephalomyelitis: Thymic dendritic-enriched cells induce specific peripheral T cell unresponsiveness in vivo. J Exp Med 182: 357-366, 1995
-
(1995)
J Exp Med
, vol.182
, pp. 357-366
-
-
Khoury, S.J.1
Gallon, L.2
Chen, W.3
Betres, K.4
Russell, M.E.5
Hancock, W.W.6
Carpenter, C.B.7
Sayegh, M.H.8
Weiner, H.L.9
-
5
-
-
0030587810
-
Ex vivo treatment of antigen-presenting cells with CTLA4Ig and encephalitogenic peptide prevents experimental autoimmune encephalomyelitis in the Lewis rat
-
Khoury SJ, Gallon L, Verburg RR, Chandraker A, Peach R, Linsley PS, Turka LA, Hancock WW, Sayegh MH: Ex vivo treatment of antigen-presenting cells with CTLA4Ig and encephalitogenic peptide prevents experimental autoimmune encephalomyelitis in the Lewis rat. J Immunol 157: 3700-3705, 1996
-
(1996)
J Immunol
, vol.157
, pp. 3700-3705
-
-
Khoury, S.J.1
Gallon, L.2
Verburg, R.R.3
Chandraker, A.4
Peach, R.5
Linsley, P.S.6
Turka, L.A.7
Hancock, W.W.8
Sayegh, M.H.9
-
6
-
-
0028903939
-
CD28 -B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2
-
Sayegh MH, Akalin E, Hancock WW, Russell ME, Carpenter CB, Linsley PS, Turka LA: CD28 -B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2. J Exp Med 181: 1869-1874, 1995
-
(1995)
J Exp Med
, vol.181
, pp. 1869-1874
-
-
Sayegh, M.H.1
Akalin, E.2
Hancock, W.W.3
Russell, M.E.4
Carpenter, C.B.5
Linsley, P.S.6
Turka, L.A.7
-
7
-
-
0035869432
-
IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo
-
Hara M, Kingsley CI, Niimi M, Read S, Turvey SE, Bushell AR, Morris PJ, Powrie F, Wood KJ: IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo. J Immunol 166: 3789 -3796, 2001
-
(2001)
J Immunol
, vol.166
, pp. 3789-3796
-
-
Hara, M.1
Kingsley, C.I.2
Niimi, M.3
Read, S.4
Turvey, S.E.5
Bushell, A.R.6
Morris, P.J.7
Powrie, F.8
Wood, K.J.9
-
8
-
-
0037025943
-
Donor- type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft- versus-host disease after allogeneic bone marrow transplantation
-
Hoffmann P, Ermann J, Edinger M, Fathman CG, Strober S: Donor- type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft- versus-host disease after allogeneic bone marrow transplantation. J Exp Med 196: 389 -399, 2002
-
(2002)
J Exp Med
, vol.196
, pp. 389-399
-
-
Hoffmann, P.1
Ermann, J.2
Edinger, M.3
Fathman, C.G.4
Strober, S.5
-
9
-
-
0028949152
-
B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
-
Kuchroo VK, Das MP, Brown JA, Ranger AM, Zamvil SS, Sobel RA, Weiner HL, Nabavi N, Glimcher LH: B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy. Cell 80: 707-718, 1995
-
(1995)
Cell
, vol.80
, pp. 707-718
-
-
Kuchroo, V.K.1
Das, M.P.2
Brown, J.A.3
Ranger, A.M.4
Zamvil, S.S.5
Sobel, R.A.6
Weiner, H.L.7
Nabavi, N.8
Glimcher, L.H.9
-
10
-
-
0037018104
-
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
-
Barrat FJ, Cua DJ, Boonstra A, Richards DF, Crain C, Savelkoul HF, de Waal-Malefyt R, Coffman RL, Hawrylowicz CM, O'Garra A: In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med 195: 603-616, 2002
-
(2002)
J Exp Med
, vol.195
, pp. 603-616
-
-
Barrat, F.J.1
Cua, D.J.2
Boonstra, A.3
Richards, D.F.4
Crain, C.5
Savelkoul, H.F.6
de Waal-Malefyt, R.7
Coffman, R.L.8
Hawrylowicz, C.M.9
O'Garra, A.10
-
11
-
-
0030849309
-
Balancing the immune system for tolerance: A case for regulatory CD4 cells
-
Field EH, Gao Q, Chen NX, Rouse TM: Balancing the immune system for tolerance: A case for regulatory CD4 cells. Transplantation 64: 1-7, 1997
-
(1997)
Transplantation
, vol.64
, pp. 1-7
-
-
Field, E.H.1
Gao, Q.2
Chen, N.X.3
Rouse, T.M.4
-
12
-
-
0031056012
-
Manipulation of cytokine networks in transplantation: False hope or realistic opportunity for tolerance?
-
Nickerson P, Steiger J, Zheng XX, Steele AW, Steurer W, Roy-Chaudhury P, Strom TB: Manipulation of cytokine networks in transplantation: False hope or realistic opportunity for tolerance? Transplantation 63: 489-494, 1997
-
(1997)
Transplantation
, vol.63
, pp. 489-494
-
-
Nickerson, P.1
Steiger, J.2
Zheng, X.X.3
Steele, A.W.4
Steurer, W.5
Roy-Chaudhury, P.6
Strom, T.B.7
-
13
-
-
0030951832
-
Are Th2 helper T lymphocytes beneficial, deleterious, or irrelevant in promoting allograft survival?
-
Piccotti JR, Chan SY, VanBuskirk AM, Eichwald EJ, Bishop DK: Are Th2 helper T lymphocytes beneficial, deleterious, or irrelevant in promoting allograft survival? Transplantation 63: 619 -624, 1997
-
(1997)
Transplantation
, vol.63
, pp. 619-624
-
-
Piccotti, J.R.1
Chan, S.Y.2
VanBuskirk, A.M.3
Eichwald, E.J.4
Bishop, D.K.5
-
14
-
-
33847667225
-
The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease
-
Afzali B, Lombardi G, Lechler RI, Lord GM: The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol 148: 32-46, 2007
-
(2007)
Clin Exp Immunol
, vol.148
, pp. 32-46
-
-
Afzali, B.1
Lombardi, G.2
Lechler, R.I.3
Lord, G.M.4
-
15
-
-
36248975343
-
Interleukin-23 and TH17 cells in transplantation immunity: Does 23+ 17 equal rejection?
-
Chen Y, Wood KJ: Interleukin-23 and TH17 cells in transplantation immunity: Does 23+ 17 equal rejection? Transplantation 84: 1071-1074, 2007
-
(2007)
Transplantation
, vol.84
, pp. 1071-1074
-
-
Chen, Y.1
Wood, K.J.2
-
16
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT: Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 6: 1123-1132, 2005
-
(2005)
Nat Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
17
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park H, Li Z, Yang XO, Chang SH, Nurieva R, Wang YH, Wang Y, Hood L, Zhu Z, Tian Q, Dong C: A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 6: 1133-1141, 2005
-
(2005)
Nat Immunol
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.H.6
Wang, Y.7
Hood, L.8
Zhu, Z.9
Tian, Q.10
Dong, C.11
-
18
-
-
0035062434
-
Regulatory functions of self-restricted MHC class II allopeptide-specific Th2 clones in vivo
-
Waaga AM, Gasser M, Kist-van Holthe JE, Najafian N, Muller A, Vella JP, Womer KL, Chandraker A, Khoury SJ, Sayegh MH: Regulatory functions of self-restricted MHC class II allopeptide-specific Th2 clones in vivo. J Clin Invest 107: 909-916, 2001
-
(2001)
J Clin Invest
, vol.107
, pp. 909-916
-
-
Waaga, A.M.1
Gasser, M.2
Kist-van Holthe, J.E.3
Najafian, N.4
Muller, A.5
Vella, J.P.6
Womer, K.L.7
Chandraker, A.8
Khoury, S.J.9
Sayegh, M.H.10
-
19
-
-
0033932757
-
Human allograft acceptance is associated with immune regulation
-
VanBuskirk AM, Burlingham WJ, Jankowska-Gan E, Chin T, Kusaka S, Geissler F, Pelletier RP, Orosz CG: Human allograft acceptance is associated with immune regulation. J Clin Invest 106: 145-155, 2000
-
(2000)
J Clin Invest
, vol.106
, pp. 145-155
-
-
VanBuskirk, A.M.1
Burlingham, W.J.2
Jankowska-Gan, E.3
Chin, T.4
Kusaka, S.5
Geissler, F.6
Pelletier, R.P.7
Orosz, C.G.8
-
20
-
-
1542378805
-
Chronic rejection: Insights from a novel immunosuppressive-free model of kidney transplantation
-
Gasser M, Waaga-Gasser AM, Kist-van Holthe JE, Yuan X, Lenhard SM, Abdallah KA, Chandraker A: Chronic rejection: Insights from a novel immunosuppressive-free model of kidney transplantation. J Am Soc Nephrol 15: 687-694, 2004
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 687-694
-
-
Gasser, M.1
Waaga-Gasser, A.M.2
Kist-van Holthe, J.E.3
Yuan, X.4
Lenhard, S.M.5
Abdallah, K.A.6
Chandraker, A.7
-
21
-
-
0037443415
-
The role of the CD134-CD134 ligand costimulatory pathway in alloimmune responses in vivo
-
Yuan X, Salama AD, Dong V, Schmitt I, Najafian N, Chandraker A, Akiba H, Yagita H, Sayegh MH: The role of the CD134-CD134 ligand costimulatory pathway in alloimmune responses in vivo. J Immunol 170: 2949 -2955, 2003
-
(2003)
J Immunol
, vol.170
, pp. 2949-2955
-
-
Yuan, X.1
Salama, A.D.2
Dong, V.3
Schmitt, I.4
Najafian, N.5
Chandraker, A.6
Akiba, H.7
Yagita, H.8
Sayegh, M.H.9
-
22
-
-
0029864501
-
Blockade of T-cell costimulation prevents development of experimental chronic renal allograft rejection
-
Azuma H, Chandraker A, Nadeau K, Hancock WW, Carpenter CB, Tilney NL, Sayegh MH: Blockade of T-cell costimulation prevents development of experimental chronic renal allograft rejection. Proc Natl Acad Sci U S A 93: 12439-12444, 1996
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 12439-12444
-
-
Azuma, H.1
Chandraker, A.2
Nadeau, K.3
Hancock, W.W.4
Carpenter, C.B.5
Tilney, N.L.6
Sayegh, M.H.7
-
23
-
-
0029086366
-
Sequential cytokine dynamics in chronic rejection of rat renal allografts: Roles for cytokines RANTES and MCP-1
-
Nadeau KC, Azuma H, Tilney NL: Sequential cytokine dynamics in chronic rejection of rat renal allografts: roles for cytokines RANTES and MCP-1. Proc Natl Acad Sci U S A 92: 8729-8733, 1995
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 8729-8733
-
-
Nadeau, K.C.1
Azuma, H.2
Tilney, N.L.3
-
24
-
-
34547150491
-
What does the future hold for cell-based tolerogenic therapy?
-
Bluestone JA, Thomson AW, Shevach EM, Weiner HL: What does the future hold for cell-based tolerogenic therapy? Nat Rev Immunol 7: 650-654, 2007
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 650-654
-
-
Bluestone, J.A.1
Thomson, A.W.2
Shevach, E.M.3
Weiner, H.L.4
-
25
-
-
0033610271
-
Chronic allograft rejection: Do the Th2 cells preferentially induced by indirect alloantigen recognition play a dominant role?
-
Shirwan H: Chronic allograft rejection: Do the Th2 cells preferentially induced by indirect alloantigen recognition play a dominant role? Transplantation 68: 715-726, 1999
-
(1999)
Transplantation
, vol.68
, pp. 715-726
-
-
Shirwan, H.1
-
26
-
-
0032706818
-
The B7-CD28/CTLA-4 costimulatory pathways in autoimmune disease of the central nervous system
-
Anderson DE, Sharpe AH, Hafler DA: The B7-CD28/CTLA-4 costimulatory pathways in autoimmune disease of the central nervous system. Curr Opin Immunol 11: 677-683, 1999
-
(1999)
Curr Opin Immunol
, vol.11
, pp. 677-683
-
-
Anderson, D.E.1
Sharpe, A.H.2
Hafler, D.A.3
-
27
-
-
0031279215
-
Distinct roles for B7-1 and B7-2 determinants during priming of effector CD8+ Tc1 and regulatory CD4+ Th2 cells for contact hypersensitivity
-
Xu H, Heeger PS, Fairchild RL: Distinct roles for B7-1 and B7-2 determinants during priming of effector CD8+ Tc1 and regulatory CD4+ Th2 cells for contact hypersensitivity. J Immunol 159: 4217-4226, 1997
-
(1997)
J Immunol
, vol.159
, pp. 4217-4226
-
-
Xu, H.1
Heeger, P.S.2
Fairchild, R.L.3
-
28
-
-
0034650487
-
Blockade of CTLA-4 signals inhibits Th2- mediated murine chronic graft-versus-host disease by an enhanced expansion of regulatory CD8+ T cells
-
Sakurai J, Ohata J, Saito K, Miyajima H, Hirano T, Kohsaka T, Enomoto S, Okumura K, Azuma M: Blockade of CTLA-4 signals inhibits Th2- mediated murine chronic graft-versus-host disease by an enhanced expansion of regulatory CD8+ T cells. J Immunol 164: 664-669, 2000
-
(2000)
J Immunol
, vol.164
, pp. 664-669
-
-
Sakurai, J.1
Ohata, J.2
Saito, K.3
Miyajima, H.4
Hirano, T.5
Kohsaka, T.6
Enomoto, S.7
Okumura, K.8
Azuma, M.9
-
29
-
-
20544435022
-
Tolerance to rat heart grafts induced by intrathymic immunomodulation is mediated by indirect recognition primed CD4+ CD25+ Treg cells
-
Koksoy S, Elpek KG, Yolcu ES, Shirwan H: Tolerance to rat heart grafts induced by intrathymic immunomodulation is mediated by indirect recognition primed CD4+ CD25+ Treg cells. Transplantation 79: 1492-1497, 2005
-
(2005)
Transplantation
, vol.79
, pp. 1492-1497
-
-
Koksoy, S.1
Elpek, K.G.2
Yolcu, E.S.3
Shirwan, H.4
-
30
-
-
0035991568
-
Regulatory functions of alloreactive Th2 clones in human renal transplant recipients
-
Kist-van Holthe JE, Gasser M, Womer K, Najafian N, Dong V, Sam- sonov DV, Geehan CS, Chandraker A, Sayegh MH, Waaga AM: Regulatory functions of alloreactive Th2 clones in human renal transplant recipients. Kidney Int 62: 627-631, 2002
-
(2002)
Kidney Int
, vol.62
, pp. 627-631
-
-
Kist-van Holthe, J.E.1
Gasser, M.2
Womer, K.3
Najafian, N.4
Dong, V.5
Sam- sonov, D.V.6
Geehan, C.S.7
Chandraker, A.8
Sayegh, M.H.9
Waaga, A.M.10
-
31
-
-
1642412617
-
The antagonism of calcineurin inhibitors and costimulatory blockers: Fact or fiction?
-
Izawa A, Sayegh MH, Chandraker A: The antagonism of calcineurin inhibitors and costimulatory blockers: Fact or fiction? Transplant Proc 36: 570S-573S, 2004
-
(2004)
Transplant Proc
, vol.36
-
-
Izawa, A.1
Sayegh, M.H.2
Chandraker, A.3
-
32
-
-
0032522524
-
Mechanisms of indirect allorecognition: Characterization of MHC class II allopeptide-specific T helper cell clones from animals undergoing acute allograft rejection
-
Waaga AM, Chandraker A, Spadafora-Ferreira M, Iyengar AR, Khoury SJ, Carpenter CB, Sayegh MH: Mechanisms of indirect allorecognition: Characterization of MHC class II allopeptide-specific T helper cell clones from animals undergoing acute allograft rejection. Transplantation 65: 876-883, 1998
-
(1998)
Transplantation
, vol.65
, pp. 876-883
-
-
Waaga, A.M.1
Chandraker, A.2
Spadafora-Ferreira, M.3
Iyengar, A.R.4
Khoury, S.J.5
Carpenter, C.B.6
Sayegh, M.H.7
-
33
-
-
0032975919
-
Cellular and humoral mechanisms of vascularized allograft rejection induced by indirect recognition of donor MHC allopeptides
-
Vella JP, Magee C, Vos L, Womer K, Rennke H, Carpenter CB, Hancock W, Sayegh MH: Cellular and humoral mechanisms of vascularized allograft rejection induced by indirect recognition of donor MHC allopeptides. Transplantation 67: 1523-1532, 1999
-
(1999)
Transplantation
, vol.67
, pp. 1523-1532
-
-
Vella, J.P.1
Magee, C.2
Vos, L.3
Womer, K.4
Rennke, H.5
Carpenter, C.B.6
Hancock, W.7
Sayegh, M.H.8
-
34
-
-
0027428113
-
Cytokines, adhesion molecules, and the pathogenesis of chronic rejection of rat renal allografts
-
Hancock WH, Whitley WD, Tullius SG, Heemann UW, Wasowska B, Baldwin WM, 3rd, Tilney NL: Cytokines, adhesion molecules, and the pathogenesis of chronic rejection of rat renal allografts. Transplantation 56: 643-650, 1993
-
(1993)
Transplantation
, vol.56
, pp. 643-650
-
-
Hancock, W.H.1
Whitley, W.D.2
Tullius, S.G.3
Heemann, U.W.4
Wasowska, B.5
Baldwin 3rd, W.M.6
Tilney, N.L.7
-
35
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
|