메뉴 건너뛰기




Volumn 52, Issue 2, 2003, Pages 356-364

Stimulation of insulin secretion by denatonium, one of the most bitter-tasting substances known

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; CELL PROTEIN; CYCLIC AMP; DENATONIUM BENZOATE; GLIBENCLAMIDE; GUSTDUCIN; NITRENDIPINE; POTASSIUM CHANNEL; SULFONYLUREA RECEPTOR; TRANSDUCIN; UNCLASSIFIED DRUG;

EID: 0037315194     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.52.2.356     Document Type: Article
Times cited : (26)

References (34)
  • 2
    • 0034677645 scopus 로고    scopus 로고
    • The physiology of taste, vintage 2000
    • Dulac C: The physiology of taste, vintage 2000. Cell 100:607-610, 2000
    • (2000) Cell , vol.100 , pp. 607-610
    • Dulac, C.1
  • 3
    • 0033034033 scopus 로고    scopus 로고
    • Cellular mechanisms of taste transduction
    • Herness MC, Gilbertson TA: Cellular mechanisms of taste transduction. Annu Rev Physiol 61:873-900, 1999
    • (1999) Annu Rev Physiol , vol.61 , pp. 873-900
    • Herness, M.C.1    Gilbertson, T.A.2
  • 5
    • 0034611738 scopus 로고    scopus 로고
    • A family of candidate taste receptors in human and mouse
    • Matsunami H, Montmayeur J-P, Buck LB: A family of candidate taste receptors in human and mouse. Nature 404:601-604, 2000
    • (2000) Nature , vol.404 , pp. 601-604
    • Matsunami, H.1    Montmayeur, J.-P.2    Buck, L.B.3
  • 6
    • 0034737382 scopus 로고    scopus 로고
    • Co-expression of calcium signaling components in vertebrate taste bud cells
    • Asano-Miyoshi M, Abe K, Emori Y: Co-expression of calcium signaling components in vertebrate taste bud cells. Neurosci Lett 283:61-64, 2000
    • (2000) Neurosci Lett , vol.283 , pp. 61-64
    • Asano-Miyoshi, M.1    Abe, K.2    Emori, Y.3
  • 7
    • 0035936911 scopus 로고    scopus 로고
    • Taste receptor cells that discriminate between bitter stimuli
    • Caicedo A, Roper SD: Taste receptor cells that discriminate between bitter stimuli. Science 291:1557-1560, 2001
    • (2001) Science , vol.291 , pp. 1557-1560
    • Caicedo, A.1    Roper, S.D.2
  • 9
    • 0032555142 scopus 로고    scopus 로고
    • Characterization and solubilization of bitter-responsive receptors that couple to gustducin
    • Ming D, Ruiz-Avila L, Margolskee R: Characterization and solubilization of bitter-responsive receptors that couple to gustducin. Proc Natl Acad Sci U S A 95:8933-8938, 1998
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8933-8938
    • Ming, D.1    Ruiz-Avila, L.2    Margolskee, R.3
  • 10
    • 0029957779 scopus 로고    scopus 로고
    • Transduction of bitter and sweet taste by gustducin
    • Wong GT, Gannon KS, Margolskee RF: Transduction of bitter and sweet taste by gustducin. Nature 381:796-800, 1996
    • (1996) Nature , vol.381 , pp. 796-800
    • Wong, G.T.1    Gannon, K.S.2    Margolskee, R.F.3
  • 12
    • 0032573151 scopus 로고    scopus 로고
    • The helical domain of a G protein alpha subunit is a regulator of its effector
    • Liu W, Northup JK: The helical domain of a G protein alpha subunit is a regulator of its effector. Proc Natl Acad Sci U S A 95:12878-12883, 1998
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 12878-12883
    • Liu, W.1    Northup, J.K.2
  • 13
    • 0034998556 scopus 로고    scopus 로고
    • Bitter taste transduced by PLC-beta(2)-dependent rise in IP(3) and alpha-gustducin-dependent fall in cyclic nucleotides
    • Yan W, Sunavala G, Rosenzweig S, Dasso M, Brand JG, Spielman AI: Bitter taste transduced by PLC-beta(2)-dependent rise in IP(3) and alpha-gustducin-dependent fall in cyclic nucleotides. Am J Physiol Cell Physiol 280:C742-C751, 2001
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Yan, W.1    Sunavala, G.2    Rosenzweig, S.3    Dasso, M.4    Brand, J.G.5    Spielman, A.I.6
  • 15
    • 0031735630 scopus 로고    scopus 로고
    • Identification of a phospholipase C beta subtype in rat taste cells
    • Rossler P, Kroner C, Freitag J, Noe J, Breer H: Identification of a phospholipase C beta subtype in rat taste cells. Eur J Cell Biol 77:253-261, 1998
    • (1998) Eur J Cell Biol , vol.77 , pp. 253-261
    • Rossler, P.1    Kroner, C.2    Freitag, J.3    Noe, J.4    Breer, H.5
  • 16
    • 0029671153 scopus 로고    scopus 로고
    • 2+ in response to sugars and non-sugar sweeteners in transduction of sweet taste in the rat
    • 2+ in response to sugars and non-sugar sweeteners in transduction of sweet taste in the rat. J Physiol 490:325-336, 1996
    • (1996) J Physiol , vol.490 , pp. 325-336
    • Bernhardt, S.J.1    Naim, M.2    Zehavi, U.3    Lindmann, B.4
  • 17
    • 0025215960 scopus 로고
    • Identification of electrophysiologically distinct subpopulations of rat taste cells
    • Akabas M, Dodd J, al-Awqati Q: Identification of electrophysiologically distinct subpopulations of rat taste cells. J Membr Biol 114:71-78, 1990
    • (1990) J Membr Biol , vol.114 , pp. 71-78
    • Akabas, M.1    Dodd, J.2    Al-Awqati, Q.3
  • 19
    • 0033199911 scopus 로고    scopus 로고
    • Activation by bitter substances of a cationic channel in membrane patches excised from the bullfrog taste receptor cell
    • Tsunenari T, Kurahashi T, Kaneko A: Activation by bitter substances of a cationic channel in membrane patches excised from the bullfrog taste receptor cell. J Physiol 519:397-404, 1999
    • (1999) J Physiol , vol.519 , pp. 397-404
    • Tsunenari, T.1    Kurahashi, T.2    Kaneko, A.3
  • 20
    • 0035862066 scopus 로고    scopus 로고
    • 2+ on the quinine-activated current of bullfrog taste receptor cells
    • 2+ on the quinine-activated current of bullfrog taste receptor cells. J Physiol 530:235-241, 2001
    • (2001) J Physiol , vol.530 , pp. 235-241
    • Tsunenari, T.1    Kaneko, A.2
  • 21
    • 0026718951 scopus 로고
    • Gustducin is a taste-cell-specific G protein closely related to the transducins
    • McLaughlin SK, McKinnon PJ, Margolskee RF: Gustducin is a taste-cell-specific G protein closely related to the transducins. Nature 357:563-569, 1992
    • (1992) Nature , vol.357 , pp. 563-569
    • McLaughlin, S.K.1    McKinnon, P.J.2    Margolskee, R.F.3
  • 22
    • 0028360027 scopus 로고
    • Expression of cone transducin, Gz alpha, and other G-protein alpha-subunit messenger ribonucleic acids in pancreatic islets
    • Zigman JM, Westermark GT, LaMendola J, Steiner DF: Expression of cone transducin, Gz alpha, and other G-protein alpha-subunit messenger ribonucleic acids in pancreatic islets. Endocrinology 135:31-37, 1994
    • (1994) Endocrinology , vol.135 , pp. 31-37
    • Zigman, J.M.1    Westermark, G.T.2    LaMendola, J.3    Steiner, D.F.4
  • 23
    • 0014042613 scopus 로고
    • Method for the isolation of intact islets of Langerhans from the rat pancreas
    • Lacy PE, Kostianovsky M: Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 16:35-39, 1967
    • (1967) Diabetes , vol.16 , pp. 35-39
    • Lacy, P.E.1    Kostianovsky, M.2
  • 24
    • 0019441262 scopus 로고
    • Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
    • Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ: Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 391:85-100, 1981
    • (1981) Pflugers Arch , vol.391 , pp. 85-100
    • Hamill, O.P.1    Marty, A.2    Neher, E.3    Sakmann, B.4    Sigworth, F.J.5
  • 25
    • 0023795593 scopus 로고
    • Muscarinic activation of ionic currents measured by a new whole-cell recording method
    • Horn R, Marty A: Muscarinic activation of ionic currents measured by a new whole-cell recording method. J Gen Physiol 92:145-159, 1988
    • (1988) J Gen Physiol , vol.92 , pp. 145-159
    • Horn, R.1    Marty, A.2
  • 26
    • 0028070045 scopus 로고
    • Analysis of G-protein alpha and beta gamma subunits by in vitro translation
    • Neer EJ, Denker BM, Thomas TC, Schmidt CJ: Analysis of G-protein alpha and beta gamma subunits by in vitro translation. Methods Enzymol 237:226-239, 1994
    • (1994) Methods Enzymol , vol.237 , pp. 226-239
    • Neer, E.J.1    Denker, B.M.2    Thomas, T.C.3    Schmidt, C.J.4
  • 27
    • 0034053981 scopus 로고    scopus 로고
    • Pancreatic beta-cell K(ATP) channel activity and membrane-binding studies with nateglinide: A comparison with sulfonylureas and repaglinide
    • Hu S, Wang S, Fanelli B, Bell PA, Dunning BE, Geisse S, Schmitz R, Boettcher BR: Pancreatic beta-cell K(ATP) channel activity and membrane-binding studies with nateglinide: A comparison with sulfonylureas and repaglinide. J Pharmacol Exp Ther 293:444-452, 2000
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 444-452
    • Hu, S.1    Wang, S.2    Fanelli, B.3    Bell, P.A.4    Dunning, B.E.5    Geisse, S.6    Schmitz, R.7    Boettcher, B.R.8
  • 28
    • 0023819834 scopus 로고
    • 2+ currents in insulin-secreting cells are activated by glyceraldehyde stimulation
    • 2+ currents in insulin-secreting cells are activated by glyceraldehyde stimulation. FEBS Lett 231:366-370, 1988
    • (1988) FEBS Lett , vol.231 , pp. 366-370
    • Velasco, J.M.1    Petersen, J.U.H.2    Petersen, O.H.3
  • 31
    • 0032885235 scopus 로고    scopus 로고
    • Structural requirements of sulphonylureas and analogues for interaction with sulphonylurea receptor subtypes
    • Meyer M, Chudziak F, Schwanstecher C, Schwanstecher M, Panten U: Structural requirements of sulphonylureas and analogues for interaction with sulphonylurea receptor subtypes. Br J Pharmacol 128:27-34, 1999
    • (1999) Br J Pharmacol , vol.128 , pp. 27-34
    • Meyer, M.1    Chudziak, F.2    Schwanstecher, C.3    Schwanstecher, M.4    Panten, U.5
  • 32
    • 0032858577 scopus 로고    scopus 로고
    • Mechanism of action of a new class of insulin secretagogues
    • Malaisse WJ: Mechanism of action of a new class of insulin secretagogues. Exp Clin Endocrinol Diabetes 107:S140-S143, 1999
    • (1999) Exp Clin Endocrinol Diabetes , vol.107
    • Malaisse, W.J.1
  • 34
    • 0036723838 scopus 로고    scopus 로고
    • Differential interactions of nateglinide and repaglinide on the human β-cell sulphonylurea receptor 1
    • Hansen AMK, Christensen IT, Hansen JB, Carr RD, Wahl P: Differential interactions of nateglinide and repaglinide on the human β-cell sulphonylurea receptor 1. Diabetes 51:2789-2795, 2002
    • (2002) Diabetes , vol.51 , pp. 2789-2795
    • Hansen, A.M.K.1    Christensen, I.T.2    Hansen, J.B.3    Carr, R.D.4    Wahl, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.