Characterization of the helicobacter pylori vacuolating cytotoxin gene in gastric biopsy specimens from patients living in tolima, Colombia;Caracterización del gen de la citotoxina vacuolizante de Helicobacter pylori a partir de biopsias gástricas de pacientes residentes en Tolima, Colombia

Revista Argentina de Microbiologia

Volumn 41, Issue 1, 2009, Pages 4-10

  Lopez A M ^a   Delgado, M P ^a   Jaramillo, C ^a   Amezquita A ^a   Parra, G ^b   Echeverry, M M ^b  

^a UNIVERSIDAD DE LOS ANDES   (Colombia)

^b UNIVERSIDAD DEL TOLIMA   (Colombia)

Author keywords

Colombia; Detection; Helicobacter pylori; Tolima; VacA

Indexed keywords

RIBOSOME DNA; VACUOLATING TOXIN;

ARTICLE; BACTERIAL GENE; COLOMBIA; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA EXTRACTION; FEMALE; GASTROINTESTINAL SYMPTOM; GENE AMPLIFICATION; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; STOMACH BIOPSY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTERIAL PROTEINS; BIOPSY; COLOMBIA; DNA, BACTERIAL; DNA, RIBOSOMAL; FEMALE; GASTRITIS; GENES, BACTERIAL; GENOTYPE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MIDDLE AGED; RNA, BACTERIAL; RNA, RIBOSOMAL, 16S; SENSITIVITY AND SPECIFICITY; STOMACH; VIRULENCE; YOUNG ADULT;

EID: 65249094822     PISSN: 03257541     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Aim RA, Ling LS, Moir DT, King BL, Brown ED, Doig PC, et al. Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori. Nature 1999, 397: 176-80.
2. Amieva MR, Salama NR, Tompkins LS, Falkow S. Helicobacter pylori enter and survive within multivesicular vacuoles of epithelial cells. Cell Microbiol 2002; 4: 677-90.
3. Atherton JC, Cao P, Peek RM Jr, Tummuru MKR, Blaser MJ, Cover TL. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. J Biol Chem 1995; 270: 17771-7.
4. Blanchard TG, Nedrud JG, Czinn SJ. Local and systemic antibody responses in humans with Helicobacter pylori infection. Can J Gastroenterol 1999; 13: 591-4.
5. Blaser MJ, Parsonnet J. Parasitism by the "slow" bacterium Helicobacter pylori leads to altered gastric homeostasis and neoplasia. J Clin Invest 1994; 94: 4-8.
6. Blaser MJ, Atherton JC. Helicobacter pylori persistence: biology and disease. J Clin Invest 2004; 113: 321-33.
7. Boncristiano M, Paccani SR, Barone S, Ulivieri C, Patrussi L, Ilver D, et al. The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms. J Exp Med 2003; 198: 1887-97.
8. Bravo LE, Cortes A, Carrascal E, Jaramillo R, Garcia LS. Helicobacter pylori: patologia y prevalencia en biopsias gastricas en Colombia. Colombia Med 2003; 34: 124 -31.
9. Cassaro M, Rugge M, Gutierrez O, Leandro G, Graham DY, Genta M. Topographic patterns of intestinal metaplasia and gastric cancer. Am J Gastroenterol 2001; 95: 1431-8.
10. Castillo-Rojas G, Mazari-Miriart M, López-Vidal Y. Helicobacter pylori: focus on CagA and VacA major virulence factors. Salud Publica de Mexico 2004; 538-48.
11. Cittelly DM, Huertas MG, Martinez JD, Oliveros R, Posso H, Bravo MM, et al. Los genotipos de Helicobacter pylori en gastritis no atrofica difieren de los encontrados en úlcera péptica, lesiones premalignas y cancer gástrico en Colombia. Rev Med Chil 2002; 130: 143-51.
12. Cover TL, Blaser MJ. Purification and characterization of the vacuolating toxin from Helicobacter pylori. J Biol Chem 1992; 267: 10570-5.
13. Cover TL, Krishna US, Israel DA, Peek RM Jr. Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin. Cancer Res 2003; 63: 951-7.
14. Czajkowsky DM, Iwamoto H, Cover TL, Shao Z. The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH. Proc Natl Acad Sci USA 1999; 96: 2001-6.
15. de Bernard M, Arico B, Papini E, Rizzuto R, Grandi G, Rappuoli R, et al. Helicobacter pylori toxin VacA induces vacuole formation by acting in the cell cytosol. Mol Microbiol 1997; 26: 665-74.
16. de Bernard M, Burroni D, Papini E, Rappuoli R, Telford J, Montecucco C. Identification of the Helicobacter pylori VacA toxin domain active in the cell cytosol. Infect Immun 1998; 66: 6014-6.
17. Fujikawa A, Shirasaka D, Yamamoto S, Ota H, Yahiro K, Fukada M, et al. Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori. Nat Genet 2003; 33: 375-81.
18. Galmiche A, Rassow J, Doye A, Cagnol S, Chambard JC, Contamin S, et al. The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome C release. EMBO J 2000; 19: 6361-70.
19. Gebert B, Fischer W, Weiss E, Hoffmann R, Haas R. Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation. Science 2003; 301: 1099-102.
20. Gebert B, Fischer W, Haas R. The Helicobacter pylori vacuolating cytotoxin: from cellular vacuolation to immunosuppressive activities. Rev Physiol Biochem Pharmacol 2004; 152: 205-20.
21. Hardin FJ, Wright RA. Helicobacter pylori: review and update. Hosp Physician 2002; 23-31.
22. Lee A, Fox J, Hazell S. Pathogenicity of Helicobacter pylori: a perspective. Infect Immun 1993; 1601-10.
23. Letley DP, Rhead JL, Twells RJ, Dove B, Atherton JC. Determinants of non-toxicity in the gastric pathogen Helicobacter pylori. J Biol Chem 2003; 278: 26734-41.
24. Li Y, Wandinger-Ness A, Goldenring JR, Cover TL. Clustering and redistribution of late endocytic compartments in response to Helicobacter pylori vacuolating toxin. Mol Biol Cell 2004; 15: 1946-59.
25. Logan RPH, Walker MM. Epidemiology and diagnosis of Helicobacter pylori infection. Br Med J 2001; 232: 920-2.
26. McNulty CAM, Wyatt JI. Helicobacter pylori. J Clin Pathol 1999; 52: 338-44.
27. Morales-Espinosa R, Castillo G, González-Valencia G, Ponce de León S, Cravioto A, Atherton JC, et al. Colonization of mexican patients by multiple Helicobacter pylori strains with different vacA and cagA genotypes. J Clin Microbiol 1999; 37: 3001-4.
28. Murillo LS, Land JA, Pleijster J, Bruggeman CA, Peña AS, Morré SA. Interleukin-1B (IL-1B) and interleukin-1 receptor antagonist (IL-1RN) gene polymorphisms are not associated with tubal pathology and Chlamydia trachomatis-related tubal factor subfertility. Hum Reprod 2003; 18: 2309-14.
29. Quiroga AJ, Cittelly DM, Bravo MM. Frecuencia de los genotipos babA2, oipA y cagE de Helicobacter pylori en pacientes con enfermedades gastroduodenales. Biomédica 2005; 25: 325-34.
30. Rivas-Traverso F, Hernández F. Helicobacter pylori: factores de virulencia, patología y diagnostico. Rev Biomed 2000; 11: 187-205.
31. Rittig MG, Shaw B, Letley DP, Thomas RJ, Argent RH, Atherton JC. Helicobacter pylori-induced homotypic phagosome fusion in human monocytes is independent of the bacterial vacA and cag status. Cell Microbiol 2003; 5: 887-99.
32. Saiki RK, Scharf S, Faloona F, Mullis KB, Horn GT, Erlich HA, et al. Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 1985; 230: 1350-4.
33. Suerbaum S, Michetti P. Helicobacter pylori Infection. N Engl J Med 2002; 347: 1175-86.
34. Telford JL, Covacci A, Rappuoli R, Chiara P. Immunobiology of Helicobacter pylori infection. Curr Opin Immunol 1997; 9: 498-503.
35. Thoreson ACE, Borre MB, Andersen LP, Elsborg S, Holck S, Conway P, et al. Development of a PCR-based technique for detection of Helicobacter pylori. Immunol Med Microbiol 1995; 10: 325-34.
36. Wilson IG. Inhibition and facilitation of nucleic acid amplification. Appl Environ Microbiol 1997; 63: 3741-51.
37. Yamaoka Y, Kodama T, Kita M, Imanishi J, Kashima K, Graham DY. Relationship of vacA genotypes of Helicobacter pylori to cagA status, cytotoxin production, and clinical outcome. Helicobacter 1998; 3: 241-53.