Rosiglitazone and fenofibrate improve insulin sensitivity of pre-diabetic OLETF rats by reducing malonyl-CoA levels in the liver and skeletal muscle

Life Sciences

Volumn 84, Issue 19-20, 2009, Pages 688-695

  Zhao, Zhengshan ^a,b   Lee, Yong Jik ^a   Kim, Soo Kyung ^a,c   Kim, Hae Jin ^a   Shim, Wan Sub ^a   Ahn, Chul Woo ^a   Lee, Hyun Chul ^a   Cha, Bong Soo ^a   Ma, Zhongmin Alex ^b  

^a Yonsei University College of Medicine   (South Korea)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c CHA University   (South Korea)

Author keywords

Acetyl CoA carboxylase; Fenofibrate; Malonyl CoA; Malonyl CoA decarboxylase; PPAR agonists; PPAR ; Rosiglitazone

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; CHOLESTEROL; FAT; FATTY ACID; FENOFIBRATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MALONYL COENZYME A; MALONYL COENZYME A DECARBOXYLASE; ROSIGLITAZONE; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY FAT; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME METABOLISM; INSULIN SENSITIVITY; LIPID DIET; LIPID PEROXIDATION; LIVER; MALE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; OTSUKA LONG EVANS TOKUSHIMA FATTY RAT; PROTEIN EXPRESSION; RAT; SKELETAL MUSCLE; TREATMENT DURATION; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT REDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTILIPEMIC AGENTS; BODY WEIGHT; DIABETES MELLITUS, EXPERIMENTAL; DIET; GLUCOSE TOLERANCE TEST; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; LIVER; MALE; MALONYL COENZYME A; MUSCLE, SKELETAL; PROCETOFEN; RATS; RATS, INBRED OLETF; THIAZOLIDINEDIONES;

ANIMALIA; RATTUS;

EID: 65049089643     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2009.02.021     Document Type: Article

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