Isobolographic characterization of interactions of retigabine with carbamazepine, lamotrigine, and valproate in the mouse maximal electroshock-induced seizure model

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 379, Issue 2, 2009, Pages 163-179

  Luszczki, Jarogniew J ^a   Wu, Jim Z ^c   Raszewski, Grzegorz ^b   Czuczwar, Stanislaw J ^a,b  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^b INSTITUTE OF AGRICULTURAL MEDICINE   (Poland)

^c Valeant Pharmaceuticals International   (United States)

Author keywords

Carbamazepine; Drug interactions; Isobolographic analysis; Lamotrigine; Maximal electroshock seizure test; Retigabine; Valproate

Indexed keywords

CARBAMAZEPINE; LAMOTRIGINE; RETIGABINE; VALPROIC ACID;

ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; BLOOD LEVEL; BRAIN LEVEL; CHIMNEY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; ELECTRIC SHOCK; EXPERIMENTAL MODEL; EXPERIMENTAL MOUSE; GRIP STRENGTH; LONG TERM MEMORY; MONOTHERAPY; MOTOR COORDINATION; MOTOR PERFORMANCE; MOUSE; MUSCLE STRENGTH; NONHUMAN; PASSIVE AVOIDANCE; PHARMACODYNAMICS; SEIZURE; SINGLE DRUG DOSE;

ANIMALS; ANTICONVULSANTS; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; BRAIN; CARBAMATES; CARBAMAZEPINE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; ELECTROSHOCK; INJECTIONS, INTRAPERITONEAL; MALE; MEMORY; MICE; MOTOR ACTIVITY; MUSCLE STRENGTH; PHENYLENEDIAMINES; PSYCHOMOTOR PERFORMANCE; SEIZURES; TRIAZINES; VALPROIC ACID;

EID: 64949142097     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-008-0349-9     Document Type: Article

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