-
1
-
-
2942615272
-
The epidemiology of cholangio- carcinoma
-
Shaib YA and El-Serag HB: The epidemiology of cholangio- carcinoma. Semin Liver Dis 24: 115-125, 2004.
-
(2004)
Semin Liver Dis
, vol.24
, pp. 115-125
-
-
Shaib, Y.A.1
El-Serag, H.B.2
-
2
-
-
0034982536
-
Increasing incidence and mortality of primary intrahepatic cholangiocarcinoma in the United States
-
Patel T: Increasing incidence and mortality of primary intrahepatic cholangiocarcinoma in the United States. Hepatology 33: 1353-1357, 2001.
-
(2001)
Hepatology
, vol.33
, pp. 1353-1357
-
-
Patel, T.1
-
3
-
-
0035000597
-
Increase in mortality rates from intrahepatic cholangiocarcinoma in England and Wales 1968-1998
-
Taylor-Robinson SD, Toledano MB, Arora S, Keegan J, Hargreaves S, Beck A, Khan SA, Elliott P and Thomas HC: Increase in mortality rates from intrahepatic cholangiocarcinoma in England and Wales 1968-1998. Gut 48: 816-820, 2001.
-
(2001)
Gut
, vol.48
, pp. 816-820
-
-
Taylor-Robinson, S.D.1
Toledano, M.B.2
Arora, S.3
Keegan, J.4
Hargreaves, S.5
Beck, A.6
Khan, S.A.7
Elliott, P.8
Thomas, H.C.9
-
5
-
-
0033969322
-
Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism
-
Jaiswal M, LaRusso NF, Burgart LJ and Gores GJ: Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism. Cancer Res 60: 184-190, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 184-190
-
-
Jaiswal, M.1
LaRusso, N.F.2
Burgart, L.J.3
Gores, G.J.4
-
6
-
-
2942585417
-
The molecular pathogenesis of cholangiocarcinoma
-
Berthiaume EP and Wands J: The molecular pathogenesis of cholangiocarcinoma, Semin. Liver Dis 24: 127-137, 2004.
-
(2004)
Semin. Liver Dis
, vol.24
, pp. 127-137
-
-
Berthiaume, E.P.1
Wands, J.2
-
7
-
-
33745712699
-
Nervous and neuroendocrine regulation of the pathophysiology of cholestasis and of biliary carcinogenesis, World
-
Marzioni M, Fava G and Benedetti A: Nervous and neuroendocrine regulation of the pathophysiology of cholestasis and of biliary carcinogenesis, World J Gastroenterology 12: 3471-3480, 2006.
-
(2006)
J Gastroenterology
, vol.12
, pp. 3471-3480
-
-
Marzioni, M.1
Fava, G.2
Benedetti, A.3
-
9
-
-
11244335567
-
Cholangiocarcinoma: Molecular targeting strategies for chemoprevention and therapy
-
Sirica AE: Cholangiocarcinoma: molecular targeting strategies for chemoprevention and therapy. Hepatology 41: 5-15, 2005.
-
(2005)
Hepatology
, vol.41
, pp. 5-15
-
-
Sirica, A.E.1
-
10
-
-
0031883604
-
Increased expression of interleukin- 6 and tumor necrosis factor-alpha in pathologic biliary epithelial cells: In situ and culture study
-
Yasoshima M, Kono N, Sugawara H, Katayanagi K, Harada K and Nakanuma Y: Increased expression of interleukin- 6 and tumor necrosis factor-alpha in pathologic biliary epithelial cells: in situ and culture study. Lab Invest 78: 89-100,1998.
-
(1998)
Lab Invest
, vol.78
, pp. 89-100
-
-
Yasoshima, M.1
Kono, N.2
Sugawara, H.3
Katayanagi, K.4
Harada, K.5
Nakanuma, Y.6
-
11
-
-
0033066133
-
Expression of platelet-derived growth factor in newly formed cholangiocytes during experimental biliary fibrosis in rats
-
Grappone C, Pinzani M, Parola M, Pellegrini G, Caligiuri A, DeFranco R, Marra F, Herbst H, Alpini G and Milani S: Expression of platelet-derived growth factor in newly formed cholangiocytes during experimental biliary fibrosis in rats. J Hepatol 31: 100-109, 1999.
-
(1999)
J Hepatol
, vol.31
, pp. 100-109
-
-
Grappone, C.1
Pinzani, M.2
Parola, M.3
Pellegrini, G.4
Caligiuri, A.5
DeFranco, R.6
Marra, F.7
Herbst, H.8
Alpini, G.9
Milani, S.10
-
12
-
-
0042744088
-
Transforming growth factor-beta inhibition of proteasomal activity: A potential mechanism of growth arrest
-
Tadlock L, Yamagiwa Y, Hawker J, Marienfeld C and Patel T: Transforming growth factor-beta inhibition of proteasomal activity: a potential mechanism of growth arrest. Am J Physiol Cell Physiol 285: C277-C285, 2003.
-
(2003)
Am J Physiol Cell Physiol
, vol.285
-
-
Tadlock, L.1
Yamagiwa, Y.2
Hawker, J.3
Marienfeld, C.4
Patel, T.5
-
13
-
-
0037370065
-
Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes
-
Spirli C, Fabris L, Duner E, Fiorotto R, Ballardini G, Roskams T, Larusso NF, Sonzogni A, Okolicsanyi L and Strazzabosco M: Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes. Gastroenterology 124: 737-753, 2003.
-
(2003)
Gastroenterology
, vol.124
, pp. 737-753
-
-
Spirli, C.1
Fabris, L.2
Duner, E.3
Fiorotto, R.4
Ballardini, G.5
Roskams, T.6
Larusso, N.F.7
Sonzogni, A.8
Okolicsanyi, L.9
Strazzabosco, M.10
-
14
-
-
19044383947
-
Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: Implications for carcinogenesis
-
Ishimura N, Bronk SF and Gores GJ: Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesis. Gastroenterology 128: 1354- 1368, 2005.
-
(2005)
Gastroenterology
, vol.128
, pp. 1354-1368
-
-
Ishimura, N.1
Bronk, S.F.2
Gores, G.J.3
-
15
-
-
0032737819
-
Hepatic jagged 1 expression studies
-
Louis AA, Van Eyken P, Haber BA, Hicks C, Weinmaster G, Taub R and Rand EB: Hepatic jagged 1 expression studies. Hepatology 30: 1269-1275, 1999.
-
(1999)
Hepatology
, vol.30
, pp. 1269-1275
-
-
Louis, A.A.1
Van Eyken, P.2
Haber, B.A.3
Hicks, C.4
Weinmaster, G.5
Taub, R.6
Rand, E.B.7
-
16
-
-
0029850324
-
Inhibition of granulocytic differentiation by mNotchl
-
Milner LA, Bigas A and Kopan R: Inhibition of granulocytic differentiation by mNotchl: Proc Natl Acad Sci USA 93: 13014- 13019,1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13014-13019
-
-
Milner, L.A.1
Bigas, A.2
Kopan, R.3
-
17
-
-
0034702303
-
Embryonic lethality in mice homozygous for a processing-deficient allele of Notchl
-
Huppert SS, Le A, Schroeter EH, Mumm JS, Saxena MT, Milner LA and Kopan R: Embryonic lethality in mice homozygous for a processing-deficient allele of Notchl. Nature 405: 966-970, 2000.
-
(2000)
Nature
, vol.405
, pp. 966-970
-
-
Huppert1
SS, L.A.2
Schroeter, E.H.3
Mumm, J.S.4
Saxena, M.T.5
Milner, L.A.6
Kopan, R.7
-
18
-
-
0033561454
-
Notch as a mediator of cell fate determination in hematopoiesis: Evicence and speculation
-
Milner LA and Bigas A: Notch as a mediator of cell fate determination in hematopoiesis: evicence and speculation. Blood 93: 243-248, 1999.
-
(1999)
Blood
, vol.93
, pp. 243-248
-
-
Milner, L.A.1
Bigas, A.2
-
19
-
-
10744223624
-
Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis
-
Miyamoto Y, Maitr A, Ghosh B, Zechner U, Argani P, Iacobuzio- Donahue CA, Sriuranpong V, Iso T, Meszoely IM, Wolfe MS, Hruban RH, Ball DW, Schmid RM and Leach SD: Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis. Cancer Cell 3: 565-576, 2003.
-
(2003)
Cancer Cell
, vol.3
, pp. 565-576
-
-
Miyamoto, Y.1
Maitr, A.2
Ghosh, B.3
Zechner, U.4
Argani, P.5
Iacobuzio- Donahue, C.A.6
Sriuranpong, V.7
Iso, T.8
Meszoely, I.M.9
Wolfe, M.S.10
Hruban, R.H.11
Ball, D.W.12
Schmid, R.M.13
Leach, S.D.14
-
20
-
-
18444408375
-
COX-2: A molecular target for colorectal cancer prevention
-
Brown JR and DuBois RN: COX-2: a molecular target for colorectal cancer prevention. J Clin Oncol 23: 2840-2855, 2005.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2840-2855
-
-
Brown, J.R.1
DuBois, R.N.2
-
21
-
-
0035476235
-
Constitutive expression of ErbB-2 in gallbladder epithelium results in development of adenocarcinoma
-
Kiguchi K, Carbajal S, Chan K, Beltran L, Ruffino L, Shen J, Matsumoto T, Yoshimi N and DiGiovanni J: Constitutive expression of ErbB-2 in gallbladder epithelium results in development of adenocarcinoma. Cancer Res 61: 6971-6976,2001.
-
(2001)
Cancer Res
, vol.61
, pp. 6971-6976
-
-
Kiguchi, K.1
Carbajal, S.2
Chan, K.3
Beltran, L.4
Ruffino, L.5
Shen, J.6
Matsumoto, T.7
Yoshimi, N.8
DiGiovanni, J.9
-
22
-
-
1842584647
-
Celecoxib-induced apoptosis in rat cholangiocarcinoma cells mediated by Akt inactivation and Bax translocation
-
Zhang Z, Lai GH and Sirica AE: Celecoxib-induced apoptosis in rat cholangiocarcinoma cells mediated by Akt inactivation and Bax translocation. Hepatology 39: 1028-1037, 2004.
-
(2004)
Hepatology
, vol.39
, pp. 1028-1037
-
-
Zhang, Z.1
Lai, G.H.2
Sirica, A.E.3
-
23
-
-
1542724860
-
Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: Implications for biliary tract carcinogenesis
-
Yoon JH, Canbay AE, Werneburg NW, Lee SP and Gores GJ: Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: implications for biliary tract carcinogenesis. Hepatology 39: 732- 738, 2004.
-
(2004)
Hepatology
, vol.39
, pp. 732-738
-
-
Yoon, J.H.1
Canbay, A.E.2
Werneburg, N.W.3
Lee, S.P.4
Gores, G.J.5
-
24
-
-
0034957745
-
Identification of oxysterols in human bile and pigment gallstones
-
Haigh WG and Lee SP: Identification of oxysterols in human bile and pigment gallstones. Gastroenterology 121: 118-123, 2001.
-
(2001)
Gastroenterology
, vol.121
, pp. 118-123
-
-
Haigh, W.G.1
Lee, S.P.2
-
25
-
-
0036124041
-
c-erbB-2 and c-Met expression relates to cholangiocarcinogenesis and progression of intrahepatic cholangiocarcinoma
-
Aishima SI, Taguchi KI, Sugimachi K, Shimada M, Sugimachi K and Tsuneyoshi M: c-erbB-2 and c-Met expression relates to cholangiocarcinogenesis and progression of intrahepatic cholangiocarcinoma. Histopathology 40: 269-278, 2002.
-
(2002)
Histopathology
, vol.40
, pp. 269-278
-
-
Aishima, S.I.1
Taguchi, K.I.2
Sugimachi, K.3
Shimada, M.4
Sugimachi, K.5
Tsuneyoshi, M.6
-
26
-
-
0036322129
-
ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human cholangiocarcinoma and risk conditions
-
Endo K, Yoon BI, Pairojkul C, Demetris AJ and Sirica AE: ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human cholangiocarcinoma and risk conditions. Hepatology 36: 439-450, 2002.
-
(2002)
Hepatology
, vol.36
, pp. 439-450
-
-
Endo, K.1
Yoon, B.I.2
Pairojkul, C.3
Demetris, A.J.4
Sirica, A.E.5
-
27
-
-
0036697788
-
Cyclooxygenase-2 and ERBB-2 in cholangiocarcinoma: Potential therapeutic targets
-
Sirica AE, Lai GH, Endo K, Zhang Z and Yoon BI: Cyclooxygenase-2 and ERBB-2 in cholangiocarcinoma: potential therapeutic targets. Semin Liver Dis 22: 303-313, 2002.
-
(2002)
Semin Liver Dis
, vol.22
, pp. 303-313
-
-
Sirica, A.E.1
Lai, G.H.2
Endo, K.3
Zhang, Z.4
Yoon, B.I.5
-
28
-
-
28844448140
-
ErbB-2/neu transformed rat cholangiocytes recapitulate key cellular and molecular features of human bile duct cancer
-
Lai GH, Zhang Z, Shen XN, Ward DJ, Dewitt JL, Holt SE, Rozich RA, Hixson DC and Sirica AE: ErbB-2/neu transformed rat cholangiocytes recapitulate key cellular and molecular features of human bile duct cancer. Gastroenterology 129: 2047- 2057,2005.
-
(2005)
Gastroenterology
, vol.129
, pp. 2047-2057
-
-
Lai, G.H.1
Zhang, Z.2
Shen, X.N.3
Ward, D.J.4
Dewitt, J.L.5
Holt, S.E.6
Rozich, R.A.7
Hixson, D.C.8
Sirica, A.E.9
-
29
-
-
0034110586
-
Unique epithelial cell production of hepatocyte growth factor/scatter factor by putative precancerous intestinal metaplasias and associated "intestinal-type" biliary cancer chemically induced in rat liver
-
Lai GH, Radaeva S, Nakamura T and Sirica AE: Unique epithelial cell production of hepatocyte growth factor/scatter factor by putative precancerous intestinal metaplasias and associated "intestinal-type" biliary cancer chemically induced in rat liver. Hepatology 31: 1257-1265, 2000.
-
(2000)
Hepatology
, vol.31
, pp. 1257-1265
-
-
Lai, G.H.1
Radaeva, S.2
Nakamura, T.3
Sirica, A.E.4
-
31
-
-
38549139744
-
Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma
-
Yoshikawa D, Ojima H, Iwasaki M, Hiraoka N, Kosuge T, Kasai S, Hirohashi S and Shibata T: Clinicopathological and prognostic significance of EGFR, VEGF, and HER2 expression in cholangiocarcinoma. Br J Cancer 98: 418-425, 2008.
-
(2008)
Br J Cancer
, vol.98
, pp. 418-425
-
-
Yoshikawa, D.1
Ojima, H.2
Iwasaki, M.3
Hiraoka, N.4
Kosuge, T.5
Kasai, S.6
Hirohashi, S.7
Shibata, T.8
-
32
-
-
0027942090
-
Interleukin-6 functions as an autocrine growth factor in a cholangiocarcinoma cell line
-
Okada K, Shimizu Y, Nambu S, Higuchi K and Watanabe A: Interleukin-6 functions as an autocrine growth factor in a cholangiocarcinoma cell line. J Gastroenterol Hepatol 9: 462- 467, 1994.
-
(1994)
J Gastroenterol Hepatol
, vol.9
, pp. 462-467
-
-
Okada, K.1
Shimizu, Y.2
Nambu, S.3
Higuchi, K.4
Watanabe, A.5
-
33
-
-
33845524970
-
Transforming growth factor-beta in cancer and metastasis
-
Jakowlew SB: Transforming growth factor-beta in cancer and metastasis, Cancer Metastasis Rev 25: 435-457, 2006.
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 435-457
-
-
Jakowlew, S.B.1
-
34
-
-
0034660412
-
Disrupted transforming growth factor-beta signaling and deregulated growth in human biliary tract cancer cells
-
Yazumi S, Ko K, Watanabe N, Yoshikawa K, Chiba T and Takahashi R: Disrupted transforming growth factor-beta signaling and deregulated growth in human biliary tract cancer cells. Int J Cancer 86: 782-789, 2000.
-
(2000)
Int J Cancer
, vol.86
, pp. 782-789
-
-
Yazumi, S.1
Ko, K.2
Watanabe, N.3
Yoshikawa, K.4
Chiba, T.5
Takahashi, R.6
-
35
-
-
20244366575
-
Intrahepatic cholangiocarcinoma escapes from growth inhibitory effect of transforming growth factor-beta 1 by overexpression of cyclin Dl
-
Zen Y, Harada K, Sasaki M, Chen TC, Chen MF, Yeh TS, Jan YY, Huang SF, Nimura Y and Nakanuma Y: Intrahepatic cholangiocarcinoma escapes from growth inhibitory effect of transforming growth factor-beta 1 by overexpression of cyclin Dl. Lab Invest 85: 572-581, 2005.
-
(2005)
Lab Invest
, vol.85
, pp. 572-581
-
-
Zen, Y.1
Harada, K.2
Sasaki, M.3
Chen, T.C.4
Chen, M.F.5
Yeh, T.S.6
Jan, Y.Y.7
Huang, S.F.8
Nimura, Y.9
Nakanuma, Y.10
-
36
-
-
12144249804
-
Immunohistochemical study of DPC4 and p53 proteins in gallbladder and bile duct cancers
-
Chuang SC, Lee KT, Tsai KB, Sheen PC, Nagai E, Mizumoto K and Tanaka M: Immunohistochemical study of DPC4 and p53 proteins in gallbladder and bile duct cancers. World J Surg 28: 995-1000,2004.
-
(2004)
World J Surg
, vol.28
, pp. 995-1000
-
-
Chuang, S.C.1
Lee, K.T.2
Tsai, K.B.3
Sheen, P.C.4
Nagai, E.5
Mizumoto, K.6
Tanaka, M.7
-
37
-
-
0032520915
-
Mutations of the DPC4/Smad4 gene in biliary tract carcinoma
-
Hahn SA, Bartsch D, Schroers A, Galehdari H, Becker M, Ramaswamy A, Schwarte-Waldhoff I, Maschek H and Schmiegel W: Mutations of the DPC4/Smad4 gene in biliary tract carcinoma. Cancer Res 58: 1124-1126, 1998.
-
(1998)
Cancer Res
, vol.58
, pp. 1124-1126
-
-
Hahn, S.A.1
Bartsch, D.2
Schroers, A.3
Galehdari, H.4
Becker, M.5
Ramaswamy, A.6
Schwarte-Waldhoff, I.7
Maschek, H.8
Schmiegel, W.9
-
38
-
-
33745856213
-
Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice
-
Xu X, Kobayashi S, Qiao W, Li C, Xiao C, Radaeva S, Stiles B, Wang RH, Ohara N, Yoshino T, LeRoith D, Torbenson MS, Gores GJ, Wu H, Gao B and Deng CX: Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice. J Clin Invest 116: 1843- 1852, 2006.
-
(2006)
J Clin Invest
, vol.116
, pp. 1843-1852
-
-
Xu, X.1
Kobayashi, S.2
Qiao, W.3
Li, C.4
Xiao, C.5
Radaeva, S.6
Stiles, B.7
Wang, R.H.8
Ohara, N.9
Yoshino, T.10
LeRoith, D.11
Torbenson, M.S.12
Gores, G.J.13
Wu, H.14
Gao, B.15
Deng, C.X.16
-
39
-
-
0031754499
-
Glutathione depletion is associated with decreased Bel-2 expression and increased apoptosis in cholangiocytes
-
Celli A, Que FG, Gores GJ and LaRusso NF: Glutathione depletion is associated with decreased Bel-2 expression and increased apoptosis in cholangiocytes. Am J Physiol Gastrointest Liver Physiol 275: G749-G757, 1998.
-
(1998)
Am J Physiol Gastrointest Liver Physiol
, vol.275
-
-
Celli, A.1
Que, F.G.2
Gores, G.J.3
LaRusso, N.F.4
-
40
-
-
0036050125
-
Cholangiocarcinoma: Recent progress. Part 2: molecular pathology and treatment
-
Okuda K, Nakanuma Y and Miyazaki M: Cholangiocarcinoma: recent progress. Part 2: molecular pathology and treatment. J Gastroenterol Hepatol 17: 1056-1063, 2002.
-
(2002)
J Gastroenterol Hepatol
, vol.17
, pp. 1056-1063
-
-
Okuda, K.1
Nakanuma, Y.2
Miyazaki, M.3
-
41
-
-
0034760440
-
Alterations in vesicle transport and cell polarity in rat hepatocytes subjected to mechanical or chemical cholestasis
-
Torok NJ, Larusso EM and McNiven MA: Alterations in vesicle transport and cell polarity in rat hepatocytes subjected to mechanical or chemical cholestasis. Gastroenterology 121: 1176- 1184,2001.
-
(2001)
Gastroenterology
, vol.121
, pp. 1176-1184
-
-
Torok, N.J.1
Larusso, E.M.2
McNiven, M.A.3
-
42
-
-
0029942365
-
Topographical immunohistochemical expression of bcl-2 protein in human liver lesions
-
Skopelitou A, Hadjiyannakis M, Alexopoulou V, Krikoni O, Kamina S and Agnantis N: Topographical immunohistochemical expression of bcl-2 protein in human liver lesions. Anticancer Res 16: 975-978, 1996.
-
(1996)
Anticancer Res
, vol.16
, pp. 975-978
-
-
Skopelitou, A.1
Hadjiyannakis, M.2
Alexopoulou, V.3
Krikoni, O.4
Kamina, S.5
Agnantis, N.6
-
43
-
-
0030767762
-
Bcl- 2 is overexpressed and alters the threshold for apoptosis in a cholangiocarcinoma cell line
-
Harnois DM, Que FG, Celli A, LaRusso NF and Gores GJ: Bcl- 2 is overexpressed and alters the threshold for apoptosis in a cholangiocarcinoma cell line. Hepatology 26: 884-890, 1997.
-
(1997)
Hepatology
, vol.26
, pp. 884-890
-
-
Harnois, D.M.1
Que, F.G.2
Celli, A.3
LaRusso, N.F.4
Gores, G.J.5
-
44
-
-
0028828499
-
Ki-ras mutations and p53 protein expressions in intrahepatic cholangiocarcinomas: Relation to gross tumor morphology
-
Ohashi K, Nakajima Y, Kanehiro H, Tsutsumi M, Taki J, Aomatsu Y, Yoshimura A, Ko S, Kin T and Yagura K: Ki-ras mutations and p53 protein expressions in intrahepatic cholangiocarcinomas: relation to gross tumor morphology. Gastroenterology 109: 1612-1617, 1995.
-
(1995)
Gastroenterology
, vol.109
, pp. 1612-1617
-
-
Ohashi, K.1
Nakajima, Y.2
Kanehiro, H.3
Tsutsumi, M.4
Taki, J.5
Aomatsu, Y.6
Yoshimura, A.7
Ko, S.8
Kin, T.9
Yagura, K.10
-
45
-
-
0036016638
-
Analysis of microsatellite instability, K-ras gene mutation and p53 protein overexpression in intrahepatic cholangiocarcinoma
-
Isa T, Tomita S, Nakachi A, Miyazato H, Shimoji H, Kusano T, Muto Y and Furukawa M: Analysis of microsatellite instability, K-ras gene mutation and p53 protein overexpression in intrahepatic cholangiocarcinoma. Hepatogastroenterology 49: 604-608, 2002.
-
(2002)
Hepatogastroenterology
, vol.49
, pp. 604-608
-
-
Isa, T.1
Tomita, S.2
Nakachi, A.3
Miyazato, H.4
Shimoji, H.5
Kusano, T.6
Muto, Y.7
Furukawa, M.8
-
46
-
-
0037085929
-
Nitric oxide inhibits apoptosis downstream of cytochrome c release by nitrosylating caspase 9
-
Torok NJ, Higuchi H, Bronk S and Gores GJ: Nitric oxide inhibits apoptosis downstream of cytochrome c release by nitrosylating caspase 9. Cancer Res 62: 1648-1653, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 1648-1653
-
-
Torok, N.J.1
Higuchi, H.2
Bronk, S.3
Gores, G.J.4
-
47
-
-
3042544355
-
Inducible nitric oxide synthase up-regulates cyclooxygenase-2 in mouse cholangiocytes promoting cell growth
-
Ishimura N, Bronk SF and Gores GJ: Inducible nitric oxide synthase up-regulates cyclooxygenase-2 in mouse cholangiocytes promoting cell growth. Am J Physiol Gastrointest Liver Physiol 287: G88-G95, 2004.
-
(2004)
Am J Physiol Gastrointest Liver Physiol
, vol.287
-
-
Ishimura, N.1
Bronk, S.F.2
Gores, G.J.3
-
48
-
-
0037624602
-
Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma
-
Tannapfel A, Sommerer F, Benicke M, Katalinic A, Uhlmann D, Witzigmann H, Hauss J and Wittekind C: Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma. Gut 52: 706-712, 2003.
-
(2003)
Gut
, vol.52
, pp. 706-712
-
-
Tannapfel, A.1
Sommerer, F.2
Benicke, M.3
Katalinic, A.4
Uhlmann, D.5
Witzigmann, H.6
Hauss, J.7
Wittekind, C.8
-
49
-
-
33845334168
-
Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma
-
Ura K, Obama K, Satoh S, Sakai Y, Nakamura Y and Furukawa Y: Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma. Clin Cancer Res 12: 6611-6616,2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6611-6616
-
-
Ura, K.1
Obama, K.2
Satoh, S.3
Sakai, Y.4
Nakamura, Y.5
Furukawa, Y.6
-
50
-
-
0037373855
-
Transforming growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cells
-
Benckert C, Jonas S, Cramer T, Schäfer G, Peters M, Wagner K, Radke C, Wiedenmann B, Neuhaus P, Höcker M and Rosewicz S: Transforming growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cells. Cancer Res 63: 1083-1092, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 1083-1092
-
-
Benckert, C.1
Jonas, S.2
Cramer, T.3
Schäfer, G.4
Peters, M.5
Wagner, K.6
Radke, C.7
Wiedenmann, B.8
Neuhaus, P.9
Höcker, M.10
Rosewicz, S.11
-
51
-
-
0029954681
-
Expression of immunoreactive matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in human normal livers and primary liver tumors
-
Terada T, Okada Y and Nakanuma Y: Expression of immunoreactive matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in human normal livers and primary liver tumors. Hepatology 23: 1341-1344, 1996.
-
(1996)
Hepatology
, vol.23
, pp. 1341-1344
-
-
Terada, T.1
Okada, Y.2
Nakanuma, Y.3
-
52
-
-
0037847455
-
Antisense oligodeoxynucleotides directed against aspartyl (asparaginyl) beta-hydroxylase suppress migration of cholangiocarcinoma cells
-
Maeda T, Lahousse S, Tamaki S, Tamaki S, Enjoji M, Wands JR and de la Monte SM: Antisense oligodeoxynucleotides directed against aspartyl (asparaginyl) beta-hydroxylase suppress migration of cholangiocarcinoma cells. J Hepatol 38: 615-622, 2003.
-
(2003)
J Hepatol
, vol.38
, pp. 615-622
-
-
Maeda, T.1
Lahousse, S.2
Tamaki, S.3
Tamaki, S.4
Enjoji, M.5
Wands, J.R.6
de la Monte, S.M.7
-
53
-
-
0035060101
-
NOV (nephroblastoma overexpressed) and the CCN family of genes: Structural and functional issues
-
Perbal B: NOV (nephroblastoma overexpressed) and the CCN family of genes: structural and functional issues. Mol Pathol 54: 57-79,2001.
-
(2001)
Mol Pathol
, vol.54
, pp. 57-79
-
-
Perbal, B.1
-
54
-
-
0038374805
-
Human WISPlv, a member of the CCN family, is associated with invasive cholangiocarcinoma
-
Tanaka S, Sugimachi K, Kameyama T, Maehara S, Shirabe K, Shimada M, Wands JR and Maehara Y: Human WISPlv, a member of the CCN family, is associated with invasive cholangiocarcinoma. Hepatology 37: 1122-1129, 2003.
-
(2003)
Hepatology
, vol.37
, pp. 1122-1129
-
-
Tanaka, S.1
Sugimachi, K.2
Kameyama, T.3
Maehara, S.4
Shirabe, K.5
Shimada, M.6
Wands, J.R.7
Maehara, Y.8
-
55
-
-
0031948695
-
Expression of E-cadherin, alpha-catenin, beta-catenin, and CD44 (standard and variant isoforms) in human cholangiocarcinoma: An immunohistochemical study
-
Ashida K, Terada T, Kitamura Y and Kaibara N: Expression of E-cadherin, alpha-catenin, beta-catenin, and CD44 (standard and variant isoforms) in human cholangiocarcinoma: an immunohistochemical study. Hepatology 27: 974-982,1998.
-
(1998)
Hepatology
, vol.27
, pp. 974-982
-
-
Ashida, K.1
Terada, T.2
Kitamura, Y.3
Kaibara, N.4
-
56
-
-
0037422201
-
MUC1 alters beta-catenin-dependent tumor formation and promotes cellular invasion
-
Schroeder JA, Adriance MC, Thompson MC, Camenisch TD and Gendler SJ: MUC1 alters beta-catenin-dependent tumor formation and promotes cellular invasion. Oncogene 22: 1324- 1332,2003.
-
(2003)
Oncogene
, vol.22
, pp. 1324-1332
-
-
Schroeder, J.A.1
Adriance, M.C.2
Thompson, M.C.3
Camenisch, T.D.4
Gendler, S.J.5
-
57
-
-
0036592038
-
Stimulation of alpha2-adrenergic receptor inhibits cholangiocarcinoma growth through modulation of Raf-1 and B- Raf activities
-
Kanno N, LeSage G, Phinizy JL, Glaser S, Francis H and Alpini G: Stimulation of alpha2-adrenergic receptor inhibits cholangiocarcinoma growth through modulation of Raf-1 and B- Raf activities. Hepatology 35: 1329-1340, 2002.
-
(2002)
Hepatology
, vol.35
, pp. 1329-1340
-
-
Kanno, N.1
LeSage, G.2
Phinizy, J.L.3
Glaser, S.4
Francis, H.5
Alpini, G.6
-
58
-
-
0030961763
-
Muscarinic acetylcholine receptor stimulation of biliary epithelial cells and its effect on bile secretion in the isolated perfused liver
-
Elsing C, Hubner C, Fitscher BA, Kassner A and Stremmel W: Muscarinic acetylcholine receptor stimulation of biliary epithelial cells and its effect on bile secretion in the isolated perfused liver. Hepatology 25: 804-813,1997.
-
(1997)
Hepatology
, vol.25
, pp. 804-813
-
-
Elsing, C.1
Hubner, C.2
Fitscher, B.A.3
Kassner, A.4
Stremmel, W.5
-
59
-
-
29244458370
-
Gamma-aminobutyric acid inhibits cholangiocarcinoma growth by cyclic AMP-dependent regulation of the protein kinase A/extracellular signal-regulated kinase 1/2 pathway
-
Fava G, Marucci L, Glaser S, Francis H, De Morrow S, Benedetti A, Alvaro D, Venter J, Meininger C, Patel T, Taffetani S, Marzioni M, Summers R, Reichenbach R and. Alpini G: Gamma-aminobutyric acid inhibits cholangiocarcinoma growth by cyclic AMP-dependent regulation of the protein kinase A/extracellular signal-regulated kinase 1/2 pathway. Cancer Res 65: 11437-11446,2005.
-
(2005)
Cancer Res
, vol.65
, pp. 11437-11446
-
-
Fava, G.1
Marucci, L.2
Glaser, S.3
Francis, H.4
De Morrow, S.5
Benedetti, A.6
Alvaro, D.7
Venter, J.8
Meininger, C.9
Patel, T.10
Taffetani, S.11
Marzioni, M.12
Summers, R.13
Reichenbach, R.14
Alpini, G.15
-
60
-
-
0035118918
-
2+- dependent protein kinase C-alpha
-
2+- dependent protein kinase C-alpha. J Hepatol 34: 284-291, 2001.
-
(2001)
J Hepatol
, vol.34
, pp. 284-291
-
-
Kanno, N.1
Glaser, S.2
Chowdhury, U.3
Phinizy, J.L.4
Baiocchi, L.5
Francis, H.6
LeSage, G.7
Alpini, G.8
-
61
-
-
0028074919
-
Growth- regulatory effect of gastrin on human colon cancer cell lines is determined by protein kinase a isoform content
-
Bold RJ, Alpard V, Ishizuka J and Townsend Jr CM: Growth- regulatory effect of gastrin on human colon cancer cell lines is determined by protein kinase a isoform content. Regul Pept 53: 61-70, 1994.
-
(1994)
Regul Pept
, vol.53
, pp. 61-70
-
-
Bold, R.J.1
Alpard, V.2
Ishizuka, J.3
Townsend Jr, C.M.4
-
62
-
-
0021953813
-
Effect of cholecystokinin on human cholangiocarcinoma xenografted into nude mice
-
Hudd C, Euhus DM, LaRegina MC Herbold DR, Palmer DC and Johnson FE: Effect of cholecystokinin on human cholangiocarcinoma xenografted into nude mice. Cancer Res 45: 1372- 1377,1985.
-
(1985)
Cancer Res
, vol.45
, pp. 1372-1377
-
-
Hudd, C.1
Euhus, D.M.2
LaRegina MC Herbold, D.R.3
Palmer, D.C.4
Johnson, F.E.5
-
63
-
-
0036927820
-
Cholangiocarcinoma cells express somatostatin receptor subtype 2 and respond to octreotide treatment
-
Zhao B, Zhao H, Zhao N and Zhu XG: Cholangiocarcinoma cells express somatostatin receptor subtype 2 and respond to octreotide treatment. J Hepatobiliary Pancreat Surg 9: 497-502, 2002.
-
(2002)
J Hepatobiliary Pancreat Surg
, vol.9
, pp. 497-502
-
-
Zhao, B.1
Zhao, H.2
Zhao, N.3
Zhu, X.G.4
-
64
-
-
0029078040
-
Human cholangiocarcinomas express somatostatin receptors and respond to somatostatin with growth inhibition
-
Tan CK, Podila PV, Taylor JE, Nagorney DM, Wiseman GA, Gores GJ and LaRusso NF: Human cholangiocarcinomas express somatostatin receptors and respond to somatostatin with growth inhibition. Gastroenterology 108: 1908-1916, 1995.
-
(1995)
Gastroenterology
, vol.108
, pp. 1908-1916
-
-
Tan, C.K.1
Podila, P.V.2
Taylor, J.E.3
Nagorney, D.M.4
Wiseman, G.A.5
Gores, G.J.6
LaRusso, N.F.7
-
65
-
-
0030941284
-
Tamoxifen- mediated growth inhibition of human cholangiocarcinoma
-
Sampson LK, Vickers SM, Ying W and Phillips JO: Tamoxifen- mediated growth inhibition of human cholangiocarcinoma. Cancer Res 57: 1743-1749, 1997.
-
(1997)
Cancer Res
, vol.57
, pp. 1743-1749
-
-
Sampson, L.K.1
Vickers, S.M.2
Ying, W.3
Phillips, J.O.4
-
66
-
-
0142244186
-
The combination of calmodulin antagonists and interferongamma induces apoptosis through caspase-dependent and -independent pathways in cholangiocarcinoma cells
-
Ahn EY, Pan G, Oh JH, Tytler EM and McDonald JM: The combination of calmodulin antagonists and interferongamma induces apoptosis through caspase-dependent and -independent pathways in cholangiocarcinoma cells. Am J Pathol 163: 2053- 2063,2003.
-
(2003)
Am J Pathol
, vol.163
, pp. 2053-2063
-
-
Ahn, E.Y.1
Pan, G.2
Oh, J.H.3
Tytler, E.M.4
McDonald, J.M.5
-
67
-
-
0036103159
-
Tamoxifen (TMX)/Fas-induced growth inhibition of human cholangiocarcinoma (HCC) by gamma interferon (IFN- gamma)
-
Vickers SM, Jhala NC, Ahn EY, McDonald JM, Pan G and Bland KI: Tamoxifen (TMX)/Fas-induced growth inhibition of human cholangiocarcinoma (HCC) by gamma interferon (IFN- gamma). Ann Surg 235: 872-878, 2002.
-
(2002)
Ann Surg
, vol.235
, pp. 872-878
-
-
Vickers, S.M.1
Jhala, N.C.2
Ahn, E.Y.3
McDonald, J.M.4
Pan, G.5
Bland, K.I.6
|