Chimeric constructs between two hepatitis B virus genomes confirm transcriptional impact of core promoter mutations and reveal multiple effects of core gene mutations

Virology

Volumn 387, Issue 2, 2009, Pages 364-372

  Tsai, Adrienne ^a   Kawai, Shigenobu ^a   Kwei, Karen ^a   Gewaily, Dina ^a   Hutter, Alexander ^a   Tong, David R ^a   Li, Jisu ^a   Wands, Jack R ^a   Tong, Shuping ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

Core gene; Core promoter; Core protein; DNA replication; Hepatitis B virus; Immature secretion; Naturally occurring mutations; Pregenomic RNA; Trans complementation

Indexed keywords

CHIMERIC PROTEIN; CORE PROTEIN; HEPATITIS B(E) ANTIGEN;

ARTICLE; GENE MUTATION; GENETIC ANALYSIS; HEPATITIS B VIRUS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RNA TRANSCRIPTION; SEQUENCE ANALYSIS; VIRION; VIRUS CORE; VIRUS GENOME; VIRUS REPLICATION;

CELL LINE, TUMOR; DNA, VIRAL; GENES, VIRAL; HEPATITIS B VIRUS; HUMANS; MUTATION; PROMOTER REGIONS, GENETIC; REASSORTANT VIRUSES; RNA, VIRAL; TRANSCRIPTION, GENETIC; VIRAL CORE PROTEINS; VIRUS REPLICATION; VIRUS SHEDDING;

HEPATITIS B VIRUS;

EID: 64849106105     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2009.03.002     Document Type: Article

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