Role of oxidative stress and intracellular glutathione in the sensitivity to apoptosis induced by proteasome inhibitor in thyroid cancer cells

BMC Cancer

Volumn 9, Issue , 2009, Pages

  Du, Zhen Xian ^a   Zhang, Hai Yan ^a   Meng, Xin ^a   Guan, Yifu ^a   Wang, Hua Qin ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; CASPASE 3; GLUTATHIONE; PROTEASOME; PROTEASOME INHIBITOR; REACTIVE OXYGEN METABOLITE; ADENOSINE TRIPHOSPHATE; BORONIC ACID DERIVATIVE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE SYNTHASE; PROTEINASE INHIBITOR; PYRAZINE DERIVATIVE; TIRON;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; FLOW CYTOMETRY; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; SPECTROPHOTOMETRY; THYROID CANCER; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVE SITE; GENE EXPRESSION REGULATION; GENETICS; INTRACELLULAR SPACE; METABOLISM; METHODOLOGY; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THYROID TUMOR; TUMOR CELL LINE;

1,2-DIHYDROXYBENZENE-3,5-DISULFONIC ACID DISODIUM SALT; ADENOSINE TRIPHOSPHATE; APOPTOSIS; BORONIC ACIDS; CATALYTIC DOMAIN; CELL LINE, TUMOR; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE SYNTHASE; HUMANS; INTRACELLULAR SPACE; OXIDATIVE STRESS; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PYRAZINES; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECTROPHOTOMETRY; THYROID NEOPLASMS;

EID: 64749106188     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-9-56     Document Type: Article

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