Structure and Function of the Glycopeptide N-methyltransferase MtfA, a Tool for the Biosynthesis of Modified Glycopeptide Antibiotics

Chemistry and Biology

Volumn 16, Issue 4, 2009, Pages 401-410

  Shi, Rong ^a   Lamb, Sherry S ^b   Zakeri, Bijan ^b   Proteau, Ariane ^a   Cui, Qizhi ^c   Sulea, Traian ^c   Matte, Allan ^c   Wright, Gerard D ^b   Cygler, Miroslaw ^a,c  

^a MCGILL UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

CHEMBIO

Indexed keywords

ADENOSINE; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; DRUG DERIVATIVE; METHYLTRANSFERASE; S ADENOSYL L METHIONINE DEPENDENT N METHYLTRANSFERASE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; S-ADENOSYL-L-METHIONINE-DEPENDENT N-METHYLTRANSFERASE; SINEFUNGIN; TEICOPLANIN;

ACTINOMYCETALES; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; METABOLISM; POINT MUTATION; PROTEIN BINDING; PROTEIN MULTIMERIZATION; X RAY CRYSTALLOGRAPHY;

ACTINOMYCETALES; ADENOSINE; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; METHYLTRANSFERASES; MODELS, MOLECULAR; POINT MUTATION; PROTEIN BINDING; PROTEIN MULTIMERIZATION; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE; TEICOPLANIN;

AMYCOLATOPSIS ORIENTALIS; BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; POSIBACTERIA;

EID: 64749086503     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2009.02.007     Document Type: Article

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